Search Results - "DANIELS, P."
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The Nucleotide Sensor ZBP1 and Kinase RIPK3 Induce the Enzyme IRG1 to Promote an Antiviral Metabolic State in Neurons
Published in Immunity (Cambridge, Mass.) (15-01-2019)“…As long-lived post-mitotic cells, neurons employ unique strategies to resist pathogen infection while preserving cellular function. Here, using a murine model…”
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Distinct α-Synuclein Strains Differentially Promote Tau Inclusions in Neurons
Published in Cell (03-07-2013)“…Many neurodegenerative diseases are characterized by the accumulation of insoluble protein aggregates, including neurofibrillary tangles comprised of tau…”
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Uterine-Artery Embolization or Myomectomy for Uterine Fibroids
Published in The New England journal of medicine (30-07-2020)“…In this multicenter, randomized, open-label trial that compared myomectomy with uterine-artery embolization in women who had symptomatic uterine fibroids and…”
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Fungal Planet description sheets: 625-715
Published in Persoonia (01-12-2017)“…Novel species of fungi described in this study include those from various countries as follows: Antarctica: Cadophora antarctica from soil. Australia: Alfaria…”
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Intratumoral activation of the necroptotic pathway components RIPK1 and RIPK3 potentiates antitumor immunity
Published in Science immunology (21-06-2019)“…Although the signaling events that induce different forms of programmed cell death are well defined, the subsequent immune responses to dying cells in the…”
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Knocking on Closed Doors: Host Interferons Dynamically Regulate Blood-Brain Barrier Function during Viral Infections of the Central Nervous System
Published in PLoS pathogens (01-09-2015)“… Neurotropic arboviruses capable of infecting the CNS include members of the Flaviviridae (e.g., West Nile and Japanese encephalitis viruses), Bunyaviridae…”
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Pulse oximetry screening for congenital heart defects in newborn infants (PulseOx): a test accuracy study
Published in The Lancet (British edition) (2011)“…Summary Background Screening for congenital heart defects relies on antenatal ultrasonography and postnatal clinical examination; however, life-threatening…”
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Secretion of fatty acid binding protein aP2 from adipocytes through a nonclassical pathway in response to adipocyte lipase activity
Published in Journal of lipid research (01-02-2015)“…Adipocyte fatty acid binding protein 4, aP2, contributes to the pathogenesis of several common diseases including type 2 diabetes, atherosclerosis, fatty liver…”
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The connection between water and energy in cities: a review
Published in Water science and technology (01-01-2011)“…We have only rudimentary understanding of the complex and pervasive connections between water and energy in cities. As water security now threatens energy and…”
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Scurvy Due to Selective Diet in a Seemingly Healthy 4-Year-Old Boy
Published in Pediatrics (Evanston) (01-09-2019)“…Scurvy is a rare disease in developed nations. In the field of pediatrics, it primarily is seen in children with developmental and behavioral issues,…”
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Viral pathogen-associated molecular patterns regulate blood-brain barrier integrity via competing innate cytokine signals
Published in mBio (26-08-2014)“…Pattern recognition receptor (PRR) detection of pathogen-associated molecular patterns (PAMPs), such as viral RNA, drives innate immune responses against West…”
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RIPK3 Activation Leads to Cytokine Synthesis that Continues after Loss of Cell Membrane Integrity
Published in Cell reports (Cambridge) (27-08-2019)“…Necroptosis is a form of programmed cell death that is defined by activation of the kinase RIPK3 and subsequent cell membrane permeabilization by the effector…”
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Percutaneous vesicoamniotic shunting versus conservative management for fetal lower urinary tract obstruction (PLUTO): a randomised trial
Published in The Lancet (British edition) (02-11-2013)“…Summary Background Fetal lower urinary tract obstruction (LUTO) is associated with high perinatal and long-term childhood mortality and morbidity. We aimed to…”
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Research Priorities in Pelvic Venous Disorders in Women: Recommendations from a Multidisciplinary Research Consensus Panel
Published in Journal of vascular and interventional radiology (01-06-2019)“…Pelvic venous disorders (PeVDs) in women can present with chronic pelvic pain, lower-extremity and vulvar varicosities, lower-extremity swelling and pain, and…”
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A Randomized Trial of Progesterone in Women with Bleeding in Early Pregnancy
Published in The New England journal of medicine (09-05-2019)“…In this multicenter, randomized, double-blind, placebo-controlled trial involving women with vaginal bleeding in early pregnancy, treatment with progesterone…”
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2'-O methylation of the viral mRNA cap by West Nile virus evades ifit1-dependent and -independent mechanisms of host restriction in vivo
Published in PLoS pathogens (2012)“…Prior studies have shown that 2'-O methyltransferase activity of flaviviruses, coronaviruses, and poxviruses promotes viral evasion of Ifit1, an…”
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An X-ray diffraction study of the effects of heat treatment on bone mineral microstructure
Published in Biomaterials (01-06-2002)“…A series of human cortical bone specimens has been heated to temperatures up to 1200°C and the mineral content examined in detail by X-ray diffraction. Line…”
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RIPK3 promotes brain region-specific interferon signaling and restriction of tick-borne flavivirus infection
Published in PLoS pathogens (01-11-2023)“…Innate immune signaling in the central nervous system (CNS) exhibits many remarkable specializations that vary across cell types and CNS regions. In the…”
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Autophagic dysfunction in mucolipidosis type IV patients
Published in Human molecular genetics (01-09-2008)“…Mutations in Mucolipin 1 (MCOLN1) have been linked to mucolipidosis type IV (MLIV), a lysosomal storage disease characterized by several neurological and…”
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Fibrillar α-synuclein induces neurotoxic astrocyte activation via RIP kinase signaling and NF-κB
Published in Cell death & disease (31-07-2021)“…Parkinson’s disease (PD) is a neurodegenerative disorder characterized by the death of midbrain dopamine neurons. The pathogenesis of PD is poorly understood,…”
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