Search Results - "DANIELE, F."
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1
Overcoming TGFβ-mediated immune evasion in cancer
Published in Nature reviews. Cancer (01-01-2022)“…Transforming growth factor-β (TGFβ) signalling controls multiple cell fate decisions during development and tissue homeostasis; hence, dysregulation of this…”
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2
Genomic profiling of DNA methyltransferases reveals a role for DNMT3B in genic methylation
Published in Nature (London) (09-04-2015)“…Genome-wide localization and activity analysis of the de novo DNA methyltransferases DNMT3A and DNMT3B in mouse embryonic stem cells identifies overlapping and…”
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3
Determinants of metastatic competency in colorectal cancer
Published in Molecular oncology (01-01-2017)“…Colorectal cancer (CRC) is one of the most common cancer types and represents a major therapeutic challenge. Although initial events in colorectal…”
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4
Visualization of a short-range Wnt gradient in the intestinal stem-cell niche
Published in Nature (London) (18-02-2016)“…Generation of an epitope-tagged, functional Wnt3 knock-in allele, the signal produced by Paneth cells to regulate intestinal stem cells. Wnt signalling in the…”
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5
Site-specific integration and tailoring of cassette design for sustainable gene transfer
Published in Nature methods (01-10-2011)“…Presented is an experimental analysis of the stability of transgene expression, the perturbation of endogenous expression and the perturbation of epigenetic…”
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6
Binding of high mobility group A proteins to the mammalian genome occurs as a function of AT-content
Published in PLoS genetics (21-12-2017)“…Genomic location can inform on potential function and recruitment signals for chromatin-associated proteins. High mobility group (Hmg) proteins are of similar…”
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7
Guanine inhibits the growth of human glioma and melanoma cell lines by interacting with GPR23
Published in Frontiers in pharmacology (19-09-2022)“…Guanine-based purines (GBPs) exert numerous biological effects at the central nervous system through putative membrane receptors, the existence of which is…”
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8
Brominated Flame Retardants: Cause for Concern?
Published in Environmental health perspectives (01-01-2004)“…Brominated flame retardants (BFRs) have routinely been added to consumer products for several decades in a successful effort to reduce fire-related injury and…”
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9
Mutagenic Analysis of Hazara Nairovirus Nontranslated Regions during Single- and Multistep Growth Identifies both Attenuating and Functionally Critical Sequences for Virus Replication
Published in Journal of virology (17-08-2020)“…Hazara nairovirus (HAZV) is a member of the family in the order and closely related to Crimean-Congo hemorrhagic fever virus, which is responsible for severe…”
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10
From poor prognosis to promising treatment
Published in Science (American Association for the Advancement of Science) (08-03-2019)“…A better mouse model sheds light on immunotherapy's potential for treating metastatic cancer Over the past several decades, evidence has accumulated that…”
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11
Wnt/β-catenin signaling requires interaction of the Dishevelled DEP domain and C terminus with a discontinuous motif in Frizzled
Published in Proceedings of the National Academy of Sciences - PNAS (03-04-2012)“…Wnt binding to members of the seven-span transmembrane Frizzled (Fz) receptor family controls essential cell fate decisions and tissue polarity during…”
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12
Guanosine-Mediated Anxiolytic-Like Effect: Interplay with Adenosine A1 and A2A Receptors
Published in International journal of molecular sciences (05-12-2020)“…Acute or chronic administration of guanosine (GUO) induces anxiolytic-like effects, for which the adenosine (ADO) system involvement has been postulated yet…”
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13
NUP-98 Rearrangements Led to the Identification of Candidate Biomarkers for Primary Induction Failure in Pediatric Acute Myeloid Leukemia
Published in International journal of molecular sciences (27-04-2021)“…Conventional chemotherapy for acute myeloid leukemia regimens generally encompass an intensive induction phase, in order to achieve a morphological remission…”
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14
Tilapia fish microbial spoilage monitored by a single optical gas sensor
Published in Food control (01-07-2018)“…As consumption of fish and fish-based foods increases, non-destructive monitoring of fish freshness also becomes more prominent. Fish products are very…”
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15
Positive Caricature Transcriptomic Effects Associated with Broad Genomic Aberrations in Colorectal Cancer
Published in Scientific reports (04-10-2018)“…We re-examined the correlation between Broad Genomic Aberrations (BGAs) and transcriptomic profiles in Colorectal Cancer (CRC). Two types of BGAs have been…”
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16
Gene expression profiles in genome instability-based classes of colorectal cancer
Published in BMC cancer (18-12-2018)“…Broad copy number aberrations (BCNAs) represent a common form of genome instability in colorectal cancer (CRC). CRCs show large variations in their level of…”
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17
The Therapeutic Potential of Tackling Tumor-Induced Dendritic Cell Dysfunction in Colorectal Cancer
Published in Frontiers in immunology (06-10-2021)“…Colorectal cancer (CRC) is the third most diagnosed malignancy and the second leading cause of cancer-related deaths worldwide. Locally advanced and metastatic…”
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18
Antagonists of Wnt/β‐catenin signalling in the periodontitis associated with type 2 diabetes and smoking
Published in Journal of clinical periodontology (01-03-2018)“…Aim This study evaluated the levels of sclerostin (SOST) and Dickkopf (DKK)‐1 in the chronic periodontitis (CP) associated with type 2 diabetes (DM) and/or…”
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19
Microwave hydrodiffusion and gravity as pretreatment for grape dehydration with simultaneous obtaining of high phenolic grape extract
Published in Food chemistry (01-02-2021)“…•Obtaining two simultaneous products by MHG (pre-dehydrated grape and grape extract).•Grapes pre-dried in 10 min by MHG, other methods took over 17 h.•Grapes…”
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Assisted mobilisation in critical patients with COVID-19
Published in Pulmonology (01-03-2024)“…The therapeutic value of early physiotherapeutic treatment in critical respiratory settings has already been clearly outlined in the last fifteen years by…”
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