Search Results - "DANIEL, Hannelore"

Dietary proteins: from evolution to engineering by Daniel, Hannelore

“…Because of the indispensable amino acids dietary proteins are the most important macronutrients. Proper growth and body maintenance depends on the quantity and…”
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Diet and Gut Microbiome and the "Chicken or Egg" Problem by Daniel, Hannelore

“…Quantity and quality of the intestinal and fecal microbiome vary considerably between individuals and are dependent on a very large number of intrinsic and…”
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Molecular and integrative physiology of intestinal peptide transport by Daniel, Hannelore

“…Intestinal protein digestion generates a huge variety and quantity of short chain peptides that are absorbed into intestinal epithelial cells by the PEPT1…”
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Intestinal organoids for assessing nutrient transport, sensing and incretin secretion by Zietek, Tamara, Rath, Eva, Haller, Dirk, Daniel, Hannelore

“…Intestinal nutrient transport and sensing are of emerging interest in research on obesity and diabetes and as drug targets. Appropriate in vitro models are…”
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Taste and move: glucose and peptide transporters in the gastrointestinal tract by Daniel, Hannelore, Zietek, Tamara

“…New Findings What is the topic of this review? Nutrient absorption in the gastrointestinal tract requires membrane proteins embedded in the apical membrane of…”
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Genetics and Epigenetics in Personalized Nutrition: Evidence, Expectations, and Experiences by Holzapfel, Christina, Waldenberger, Melanie, Lorkowski, Stefan, Daniel, Hannelore

“…With the presentation of the blueprint of the first human genome in 2001 and the advent of technologies for high‐throughput genetic analysis, personalized…”
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An LC-MS/MS method to quantify acylcarnitine species including isomeric and odd-numbered forms in plasma and tissues by Giesbertz, Pieter, Ecker, Josef, Haag, Alexander, Spanier, Britta, Daniel, Hannelore

“…Acylcarnitines are intermediates of fatty acid and amino acid oxidation found in tissues and body fluids. They are important diagnostic markers for inherited…”
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The gut microbiota promotes hepatic fatty acid desaturation and elongation in mice by Kindt, Alida, Liebisch, Gerhard, Clavel, Thomas, Haller, Dirk, Hörmannsperger, Gabriele, Yoon, Hongsup, Kolmeder, Daniela, Sigruener, Alexander, Krautbauer, Sabrina, Seeliger, Claudine, Ganzha, Alexandra, Schweizer, Sabine, Morisset, Rosalie, Strowig, Till, Daniel, Hannelore, Helm, Dominic, Küster, Bernhard, Krumsiek, Jan, Ecker, Josef

“…Interactions between the gut microbial ecosystem and host lipid homeostasis are highly relevant to host physiology and metabolic diseases. We present a…”
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The role of SGLT1 and GLUT2 in intestinal glucose transport and sensing by Röder, Pia V, Geillinger, Kerstin E, Zietek, Tamara S, Thorens, Bernard, Koepsell, Hermann, Daniel, Hannelore

“…Intestinal glucose absorption is mediated by SGLT1 whereas GLUT2 is considered to provide basolateral exit. Recently, it was proposed that GLUT2 can be…”
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High-fat diet alters gut microbiota physiology in mice by Daniel, Hannelore, Gholami, Amin Moghaddas, Berry, David, Desmarchelier, Charles, Hahne, Hannes, Loh, Gunnar, Mondot, Stanislas, Lepage, Patricia, Rothballer, Michael, Walker, Alesia, Böhm, Christoph, Wenning, Mareike, Wagner, Michael, Blaut, Michael, Schmitt-Kopplin, Philippe, Kuster, Bernhard, Haller, Dirk, Clavel, Thomas

“…The intestinal microbiota is known to regulate host energy homeostasis and can be influenced by high-calorie diets. However, changes affecting the ecosystem at…”
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Metabolite profiling in plasma and tissues of ob/ob and db/db mice identifies novel markers of obesity and type 2 diabetes by Giesbertz, Pieter, Padberg, Inken, Rein, Dietrich, Ecker, Josef, Höfle, Anja S., Spanier, Britta, Daniel, Hannelore

“…Aims/hypothesis Metabolomics approaches in humans have identified around 40 plasma metabolites associated with insulin resistance (IR) and type 2 diabetes,…”
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Transport Versus Hydrolysis: Reassessing Intestinal Assimilation of Di‐ and Tripeptides by LC–MS/MS Analysis by Rohm, Florian, Daniel, Hannelore, Spanier, Britta

“…Scope The role of PEPT1 in the uptake of intact peptides as compared to hydrolysis prior to uptake of their constituents is unknown. Here, dipeptides,…”
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Flavonoid glycosides are not transported by the human Na+/glucose transporter when expressed in Xenopus laevis oocytes, but effectively inhibit electrogenic glucose uptake by Kottra, Gabor, Daniel, Hannelore

“…There is controversy as to whether intestinal absorption of glycosylated flavonoids, and particularly quercetin glycosides, involves their uptake in intact…”
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Plasma concentrations of anserine, carnosine and pi-methylhistidine as biomarkers of habitual meat consumption by Mitry, Patricia, Wawro, Nina, Rohrmann, Sabine, Giesbertz, Pieter, Daniel, Hannelore, Linseisen, Jakob

“…Background/Objectives Dietary intake of red and processed meat has been associated with disease risk. Since dietary intake assessment methods are prone to…”
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Inhibition of the intestinal sodium‐coupled glucose transporter 1 (SGLT1) by extracts and polyphenols from apple reduces postprandial blood glucose levels in mice and humans by Schulze, Christine, Bangert, Adina, Kottra, Gabor, Geillinger, Kerstin Elisabeth, Schwanck, Bettina, Vollert, Henning, Blaschek, Wolfgang, Daniel, Hannelore

“…SCOPE: There is a growing interest in food constituents that could reduce intestinal glucose absorption to prevent overshooting plasma glucose and insulin…”
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The proton oligopeptide cotransporter family SLC15 in physiology and pharmacology by Daniel, Hannelore, Kottra, Gabor

“…Mammalian members of the SLC15 family are electrogenic transporters that utilize the proton-motive force for uphill transport of short chain peptides and…”
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Biopsy samples from patients with irritable bowel syndrome, but not from those with mastocytosis or unspecific gastrointestinal complaints reveal unique nerve activation in all gut regions independent of mast cell density, histamine content or specific gastrointestinal symptoms by Vignali, Sheila, Buhner, Sabine, Greiter, Wolfgang, Daniel, Hannelore, Frieling, Thomas, Schemann, Michael, Annahazi, Anita

“…We previously showed enteric nerve activation after application of colonic mucosal biopsy supernatants from patients with irritable bowel syndrome (IBS). The…”
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Dietary fat and gut microbiota interactions determine diet-induced obesity in mice by Kübeck, Raphaela, Bonet-Ripoll, Catalina, Hoffmann, Christina, Walker, Alesia, Müller, Veronika Maria, Schüppel, Valentina Luise, Lagkouvardos, Ilias, Scholz, Birgit, Engel, Karl-Heinz, Daniel, Hannelore, Schmitt-Kopplin, Philippe, Haller, Dirk, Clavel, Thomas, Klingenspor, Martin

“…Abstract Objective Gut microbiota may promote positive energy balance; however, germfree mice can be either resistant or susceptible to diet-induced obesity…”
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The dynamic range of the human metabolome revealed by challenges by Krug, Susanne, Kastenmüller, Gabi, Stückler, Ferdinand, Rist, Manuela J., Skurk, Thomas, Sailer, Manuela, Raffler, Johannes, Römisch‐Margl, Werner, Adamski, Jerzy, Prehn, Cornelia, Frank, Thomas, Engel, Karl‐Heinz, Hofmann, Thomas, Luy, Burkhard, Zimmermann, Ralf, Moritz, Franco, Schmitt‐Kopplin, Philippe, Krumsiek, Jan, Kremer, Werner, Huber, Fritz, Oeh, Uwe, Theis, Fabian J., Szymczak, Wilfried, Hauner, Hans, Suhre, Karsten, Daniel, Hannelore

“…Metabolic challenge protocols, such as the oral glucose tolerance test, can uncover early alterations in metabolism preceding chronic diseases. Nevertheless,…”
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The HuMet Repository: Watching human metabolism at work by Weinisch, Patrick, Raffler, Johannes, Römisch-Margl, Werner, Arnold, Matthias, Mohney, Robert P., Rist, Manuela J., Prehn, Cornelia, Skurk, Thomas, Hauner, Hans, Daniel, Hannelore, Suhre, Karsten, Kastenmüller, Gabi

“…Metabolism oscillates between catabolic and anabolic states depending on food intake, exercise, or stresses that change a multitude of metabolic pathways…”
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