Search Results - "DANHORN, Thomas"

Biofilm formation by plant-associated bacteria by DANHORN, Thomas, FUQUA, Clay

“…Plants support a diverse array of bacteria, including parasites, mutualists, and commensals on and around their roots, in the vasculature, and on aerial…”
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Dietary Lipids Differentially Shape Nonalcoholic Steatohepatitis Progression and the Transcriptome of Kupffer Cells and Infiltrating Macrophages by McGettigan, Brett, McMahan, Rachel, Orlicky, David, Burchill, Matthew, Danhorn, Thomas, Francis, Prashanth, Cheng, Lin Ling, Golden‐Mason, Lucy, Jakubzick, Claudia V., Rosen, Hugo R.

“…A crucial component of nonalcoholic fatty liver disease (NAFLD) pathogenesis is lipid stress, which may contribute to hepatic inflammation and activation of…”
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Virtual memory T cells develop and mediate bystander protective immunity in an IL-15-dependent manner by White, Jason T., Cross, Eric W., Burchill, Matthew A., Danhorn, Thomas, McCarter, Martin D., Rosen, Hugo R., O’Connor, Brian, Kedl, Ross M.

“…Virtual memory cells (VM) are an antigen-specific, memory phenotype CD8 T-cell subset found in lymphoreplete, unchallenged mice. Previous studies indicated…”
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Phenazine-1-Carboxylic Acid Promotes Bacterial Biofilm Development via Ferrous Iron Acquisition by Wang, Yun, Wilks, Jessica C, Danhorn, Thomas, Ramos, Itzel, Croal, Laura, Newman, Dianne K

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GATA2 regulates mast cell identity and responsiveness to antigenic stimulation by promoting chromatin remodeling at super-enhancers by Li, Yapeng, Gao, Junfeng, Kamran, Mohammad, Harmacek, Laura, Danhorn, Thomas, Leach, Sonia M., O’Connor, Brian P., Hagman, James R., Huang, Hua

“…Mast cells are critical effectors of allergic inflammation and protection against parasitic infections. We previously demonstrated that transcription factors…”
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Motility and Chemotaxis in Agrobacterium tumefaciens Surface Attachment and Biofilm Formation by Merritt, Peter M, Danhorn, Thomas, Fuqua, Clay

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Human and Mouse Transcriptome Profiling Identifies Cross-Species Homology in Pulmonary and Lymph Node Mononuclear Phagocytes by Leach, Sonia M., Gibbings, Sophie L., Tewari, Anita D., Atif, Shaikh M., Vestal, Brian, Danhorn, Thomas, Janssen, William J., Wager, Tor D., Jakubzick, Claudia V.

“…The mononuclear phagocyte (MP) system consists of macrophages, monocytes, and dendritic cells (DCs). MP subtypes play distinct functional roles in steady-state…”
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Examination of Wnt signaling as a therapeutic target for pancreatic ductal adenocarcinoma (PDAC) using a pancreatic tumor organoid library (PTOL) by Hawkins, Hayley J, Yacob, Betelehem W, Brown, Monica E, Goldstein, Brandon R, Arcaroli, John J, Bagby, Stacey M, Hartman, Sarah J, Macbeth, Morgan, Goodspeed, Andrew, Danhorn, Thomas, Lentz, Robert W, Lieu, Christopher H, Leal, Alexis D, Messersmith, Wells A, Dempsey, Peter J, Pitts, Todd M

“…Pancreatic ductal adenocarcinoma (PDAC) presents at advanced stages and is refractory to most treatment modalities. Wnt signaling activation plays a critical…”
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Innate and adaptive signals enhance differentiation and expansion of dual-antibody autoreactive B cells in lupus by Sang, Allison, Danhorn, Thomas, Peterson, Jacob N., Rankin, Andrew L., O’Connor, Brian P., Leach, Sonia M., Torres, Raul M., Pelanda, Roberta

“…Autoreactive B cells have a major function in autoimmunity. A small subset of B cells expressing two distinct B-cell-antigen-receptors (B 2R cells) is elevated…”
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BATF acts as an essential regulator of IL-25-responsive migratory ILC2 cell fate and function by Miller, Mindy M, Patel, Preeyam S, Bao, Katherine, Danhorn, Thomas, O'Connor, Brian P, Reinhardt, R Lee

“…A transitory, interleukin-25 (IL-25)-responsive, group 2 innate lymphoid cell (ILC2) subset induced during type 2 inflammation was recently identified as…”
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Quorum sensing and motility mediate interactions between Pseudomonas aeruginosa and Agrobacterium tumefaciens in biofilm cocultures by An, D, Danhorn, T, Fuqua, C, Parsek, M.R

“…In the environment, multiple microbial taxa typically coexist as communities, competing for resources and, often, physically associated within biofilms. A…”
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Single cell analysis of host response to helminth infection reveals the clonal breadth, heterogeneity, and tissue-specific programming of the responding CD4+ T cell repertoire by Brown, Ivy K., Dyjack, Nathan, Miller, Mindy M., Krovi, Harsha, Rios, Cydney, Woolaver, Rachel, Harmacek, Laura, Tu, Ting-Hui, O’Connor, Brian P., Danhorn, Thomas, Vestal, Brian, Gapin, Laurent, Pinilla, Clemencia, Seibold, Max A., Scott-Browne, James, Santos, Radleigh G., Reinhardt, R. Lee

“…The CD4 + T cell response is critical to host protection against helminth infection. How this response varies across different hosts and tissues remains an…”
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Regulation of toll-like receptor signaling by the SF3a mRNA splicing complex by O'Connor, Brian P, Danhorn, Thomas, De Arras, Lesly, Flatley, Brenna R, Marcus, Roland A, Farias-Hesson, Eveline, Leach, Sonia M, Alper, Scott

“…The innate immune response plays a key role in fighting infection by activating inflammation and stimulating the adaptive immune response. However, chronic…”
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Gene and metabolite time-course response to cigarette smoking in mouse lung and plasma by Miller, Mikaela A, Danhorn, Thomas, Cruickshank-Quinn, Charmion I, Leach, Sonia M, Jacobson, Sean, Strand, Matthew J, Reisdorph, Nichole A, Bowler, Russell P, Petrache, Irina, Kechris, Katerina

“…Prolonged cigarette smoking (CS) causes chronic obstructive pulmonary disease (COPD), a prevalent serious condition that may persist or progress after smoking…”
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Inflammation-Induced Alternative Pre-mRNA Splicing in Mouse Alveolar Macrophages by Janssen, William J, Danhorn, Thomas, Harris, Chelsea, Mould, Kara J, Lee, Frank Fang-Yao, Hedin, Brenna R, D'Alessandro, Angelo, Leach, Sonia M, Alper, Scott

“…Alveolar macrophages serve as central orchestrators of inflammatory responses in the lungs, both initiating their onset and promoting their resolution…”
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The somatically generated portion of T cell receptor CDR3α contributes to the MHC allele specificity of the T cell receptor by Marrack, Philippa, Krovi, Sai Harsha, Silberman, Daniel, White, Janice, Kushnir, Eleanor, Nakayama, Maki, Crooks, James, Danhorn, Thomas, Leach, Sonia, Anselment, Randy, Scott-Browne, James, Gapin, Laurent, Kappler, John

“…Mature T cells bearing αβ T cell receptors react with foreign antigens bound to alleles of major histocompatibility complex proteins (MHC) that they were…”
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Deletion of c-FLIP from CD11bhi Macrophages Prevents Development of Bleomycin-induced Lung Fibrosis by McCubbrey, Alexandra L, Barthel, Lea, Mohning, Michael P, Redente, Elizabeth F, Mould, Kara J, Thomas, Stacey M, Leach, Sonia M, Danhorn, Thomas, Gibbings, Sophie L, Jakubzick, Claudia V, Henson, Peter M, Janssen, William J

“…Idiopathic pulmonary fibrosis is a progressive lung disease with complex pathophysiology and fatal prognosis. Macrophages (MΦ) contribute to the development of…”
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Phosphorus Limitation Enhances Biofilm Formation of the Plant Pathogen Agrobacterium tumefaciens through the PhoR-PhoB Regulatory System by DANHORN, Thomas, HENTZER, Morten, GIVSKOV, Michael, PARSEK, Matthew R, FUQUA, Clay

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Three Unique Interstitial Macrophages in the Murine Lung at Steady State by Gibbings, Sophie L, Thomas, Stacey M, Atif, Shaikh M, McCubbrey, Alexandra L, Desch, A Nicole, Danhorn, Thomas, Leach, Sonia M, Bratton, Donna L, Henson, Peter M, Janssen, William J, Jakubzick, Claudia V

“…The current paradigm in macrophage biology is that some tissues mainly contain macrophages from embryonic origin, such as microglia in the brain, whereas other…”
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IL-25-responsive migratory iILC2s require BATF and stably convert to tissue-resident nILC2s by Miller, Mindy M, Danhorn, Thomas, Reinhardt, R. Lee

“…Abstract Inflammatory ILC2s (iILC2s) are a transient subset of group-2 innate lymphoid cells that migrate to the lung shortly after helminth infection or IL-25…”
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