Search Results - "DANCHIN, Antoine"

In vivo, in vitro and in silico: an open space for the development of microbe‐based applications of synthetic biology by Danchin, Antoine

“…Summary Living systems are studied using three complementary approaches: living cells, cell‐free systems and computer‐mediated modelling. Progresses in…”
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Zinc, an unexpected integrator of metabolism? by Danchin, Antoine

“…Summary Even when they no longer require the presence of iron, cells use zinc as a divalent cation, involved in a large variety of catalytic and regulatory…”
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Artificial intelligence‐based prediction of pathogen emergence and evolution in the world of synthetic biology by Danchin, Antoine

“…The emergence of new techniques in both microbial biotechnology and artificial intelligence (AI) is opening up a completely new field for monitoring and…”
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Science, method and critical thinking by Danchin, Antoine

“…Science is founded on a method based on critical thinking. A prerequisite for this is not only a sufficient command of language but also the comprehension of…”
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SARS‐CoV‐2 variants: Relevance for symptom granularity, epidemiology, immunity (herd, vaccines), virus origin and containment? by Danchin, Antoine, Timmis, Kenneth

“…Summary The origin of the SARS‐CoV‐2 virus remains enigmatic. It is likely to be a continuum resulting from inevitable mutations and recombination events…”
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From chemical metabolism to life: the origin of the genetic coding process by Danchin, Antoine

“…Looking for origins is so much rooted in ideology that most studies reflect opinions that fail to explore the first realistic scenarios. To be sure, trying to…”
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From dirt to industrial applications: Pseudomonas putida as a Synthetic Biology chassis for hosting harsh biochemical reactions by Nikel, Pablo I, Chavarría, Max, Danchin, Antoine, de Lorenzo, Víctor

“…[Display omitted] •SynBio needs chassis with superior genetic, biochemical, and physiological traits.•Environmental bacteria are endowed with many advantageous…”
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Phylogenomics of expanding uncultured environmental Tenericutes provides insights into their pathogenicity and evolutionary relationship with Bacilli by Wang, Yong, Huang, Jiao-Mei, Zhou, Ying-Li, Almeida, Alexandre, Finn, Robert D, Danchin, Antoine, He, Li-Sheng

“…The metabolic capacity, stress response and evolution of uncultured environmental Tenericutes have remained elusive, since previous studies have been largely…”
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Queuine, a bacterial-derived hypermodified nucleobase, shows protection in in vitro models of neurodegeneration by Richard, Patricia, Kozlowski, Lucie, Guillorit, Hélène, Garnier, Patrice, McKnight, Nicole C, Danchin, Antoine, Manière, Xavier

“…Growing evidence suggests that human gut bacteria, which comprise the microbiome, are linked to several neurodegenerative disorders. An imbalance in the…”
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Temporal evolution of master regulator Crp identifies pyrimidines as catabolite modulator factors by Lauritsen, Ida, Frendorf, Pernille Ott, Capucci, Silvia, Heyde, Sophia A. H., Blomquist, Sarah D., Wendel, Sofie, Fischer, Emil C., Sekowska, Agnieszka, Danchin, Antoine, Nørholm, Morten H. H.

“…The evolution of microorganisms often involves changes of unclear relevance, such as transient phenotypes and sequential development of multiple adaptive…”
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One‐carbon metabolism, folate, zinc and translation by Danchin, Antoine, Sekowska, Agnieszka, You, Conghui

“…Summary The translation process, central to life, is tightly connected to the one‐carbon (1‐C) metabolism via a plethora of macromolecule modifications and…”
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Recursive genome engineering decodes the evolutionary origin of an essential thymidylate kinase activity in Pseudomonas putida KT2440 by Wirth, Nicolas T, Rohr, Katja, Danchin, Antoine, Nikel, Pablo I

“…Investigating fundamental aspects of metabolism is vital for advancing our understanding of the diverse biochemical capabilities and biotechnological…”
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A New Transmission Route for the Propagation of the SARS-CoV-2 Coronavirus by Danchin, Antoine, Ng, Tuen Wai, Turinici, Gabriel

“…Starting late 2019, a novel coronavirus spread from the capital of the Hubei province in China to the rest of the country, then to most of the world. To…”
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Revisiting the methionine salvage pathway and its paralogues by Sekowska, Agnieszka, Ashida, Hiroki, Danchin, Antoine

“…Summary Methionine is essential for life. Its chemistry makes it fragile in the presence of oxygen. Aerobic living organisms have selected a salvage pathway…”
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COVID-19 Adaptive Humoral Immunity Models: Weakly Neutralizing Versus Antibody-Disease Enhancement Scenarios by Danchin, Antoine, Pagani-Azizi, Oriane, Turinici, Gabriel, Yahiaoui, Ghozlane

“…The interplay between the virus, infected cells and immune responses to SARS-CoV-2 is still under debate. By extending the basic model of viral dynamics, we…”
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From a consortium sequence to a unified sequence: the Bacillus subtilis 168 reference genome a decade later by Barbe, Valerie, Cruveiller, Stephane, Kunst, Frank, Lenoble, Patricia, Meurice, Guillaume, Sekowska, Agnieszka, Vallenet, David, Wang, Tingzhang, Moszer, Ivan, Medigue, Claudine, Danchin, Antoine

“…1 CEA, Institut de Génomique, Génoscope, 2 rue Gaston Crémieux, 91057 Évry, France 2 CEA, Institut de Génomique, Laboratoire de Génomique Comparative/CNRS…”
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Open-Source Genomic Analysis of Shiga-Toxin–Producing E. coli O104:H4 by Rohde, Holger, Qin, Junjie, Cui, Yujun, Li, Dongfang, Li, Yin, Li, Junhua, Li, Shenghui, Li, Yingrui, Loman, Nicholas J, Hentschke, Moritz, Chen, Wentong, Pu, Fei, Peng, Yangqing, Xi, Feng, Zhang, Zhaoxi, Yang, Liang, Yang, Huanming, Yang, Ruifu, Yang, Xianwei, Zhao, Xiangna, Zhao, Meiru, Wang, Jian, Wang, Jun, Wang, Peng, Guan, Yuanlin, Cen, Zhong, Christner, Martin, Kobbe, Robin, Loos, Sebastian, Oh, Jun, Danchin, Antoine, Gao, George F, Song, Yajun, Xu, Jianguo, Pallen, Mark J, Aepfelbacher, Martin

“…The authors sequenced the genome of an isolate of E. coli obtained from a German girl with bloody diarrhea and shared the data online with other researchers,…”
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Bacillus subtilis, the model Gram‐positive bacterium: 20 years of annotation refinement by Borriss, Rainer, Danchin, Antoine, Harwood, Colin R., Médigue, Claudine, Rocha, Eduardo P.C., Sekowska, Agnieszka, Vallenet, David

“…Summary Genome annotation is, nowadays, performed via automatic pipelines that cannot discriminate between right and wrong annotations. Given their importance…”
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The Enigmatic Genome of an Obligate Ancient Spiroplasma Symbiont in a Hadal Holothurian by He, Li-Sheng, Zhang, Pei-Wei, Huang, Jiao-Mei, Zhu, Fang-Chao, Danchin, Antoine, Wang, Yong

“…Protective symbiosis has been reported in many organisms, but the molecular mechanisms of the mutualistic interactions between the symbionts and their hosts…”
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The importance of naturally attenuated SARS‐CoV‐2in the fight against COVID‐19 by Armengaud, Jean, Delaunay‐Moisan, Agnès, Thuret, Jean‐Yves, Anken, Eelco, Acosta‐Alvear, Diego, Aragón, Tomás, Arias, Carolina, Blondel, Marc, Braakman, Ineke, Collet, Jean‐François, Courcol, René, Danchin, Antoine, Deleuze, Jean‐François, Lavigne, Jean‐Philippe, Lucas, Sophie, Michiels, Thomas, Moore, Edward R. B., Nixon‐Abell, Jonathon, Rossello‐Mora, Ramon, Shi, Zheng‐Li, Siccardi, Antonio G., Sitia, Roberto, Tillett, Daniel, Timmis, Kenneth N., Toledano, Michel B., Sluijs, Peter, Vicenzi, Elisa

“…The current SARS‐CoV‐2 pandemic is wreaking havoc throughout the world and has rapidly become a global health emergency. A central question concerning COVID‐19…”
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