Search Results - "DALRYMPLE, Brian"

Beyond differential expression: the quest for causal mutations and effector molecules by Hudson, Nicholas J, Dalrymple, Brian P, Reverter, Antonio

“…High throughput gene expression technologies are a popular choice for researchers seeking molecular or systems-level explanations of biological phenomena…”
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A differential wiring analysis of expression data correctly identifies the gene containing the causal mutation by Hudson, Nicholas J, Reverter, Antonio, Dalrymple, Brian P

“…Transcription factor (TF) regulation is often post-translational. TF modifications such as reversible phosphorylation and missense mutations, which can act…”
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Fast fourier transform: A Niche, but critical strategy in optimizing impression evidence by Dalrymple, Brian

“…The evolution from film to digital as the recording medium for forensic imaging has extended the reach of forensic photographers, both in original capture and…”
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Genome Wide Survey of SNP Variation Reveals the Genetic Structure of Sheep Breeds by Kijas, James W, Townley, David, Dalrymple, Brian P, Heaton, Michael P, Maddox, Jillian F, McGrath, Annette, Wilson, Peter, Ingersoll, Roxann G, McCulloch, Russell, McWilliam, Sean, Tang, Dave, McEwan, John, Cockett, Noelle, Oddy, V. Hutton, Nicholas, Frank W, Raadsma, Herman

“…The genetic structure of sheep reflects their domestication and subsequent formation into discrete breeds. Understanding genetic structure is essential for…”
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A microRNA catalog of the developing chicken embryo identified by a deep sequencing approach by Glazov, Evgeny A, Cottee, Pauline A, Barris, Wesley C, Moore, Robert J, Dalrymple, Brian P, Tizard, Mark L

“…MicroRNA (miRNA) and other types of small regulatory RNAs play a crucial role in the regulation of gene expression in eukaryotes. Several distinct classes of…”
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Genome-wide analysis of the world's sheep breeds reveals high levels of historic mixture and strong recent selection by Kijas, James W, Lenstra, Johannes A, Hayes, Ben, Boitard, Simon, Porto Neto, Laercio R, San Cristobal, Magali, Servin, Bertrand, McCulloch, Russell, Whan, Vicki, Gietzen, Kimberly, Paiva, Samuel, Barendse, William, Ciani, Elena, Raadsma, Herman, McEwan, John, Dalrymple, Brian

“…Through their domestication and subsequent selection, sheep have been adapted to thrive in a diverse range of environments. To characterise the genetic…”
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Regulatory impact factors: unraveling the transcriptional regulation of complex traits from expression data by Reverter, Antonio, Hudson, Nicholas J., Nagaraj, Shivashankar H., Pérez-Enciso, Miguel, Dalrymple, Brian P.

“…Motivation: Although transcription factors (TF) play a central regulatory role, their detection from expression data is limited due to their low, and often…”
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Transcriptome analysis of cattle muscle identifies potential markers for skeletal muscle growth rate and major cell types by Guo, Bing, Greenwood, Paul L, Cafe, Linda M, Zhou, Guanghong, Zhang, Wangang, Dalrymple, Brian P

“…This study aimed to identify markers for muscle growth rate and the different cellular contributors to cattle muscle and to link the muscle growth rate markers…”
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A comparison of transcriptomic patterns measured in the skin of Chinese fine and coarse wool sheep breeds by Zhang, Lichun, Sun, Fuliang, Jin, Haiguo, Dalrymple, Brian P., Cao, Yang, Wei, Tian, Vuocolo, Tony, Zhang, Mingxin, Piao, Qinlin, Ingham, Aaron B.

“…We characterised wool traits, and skin gene expression profiles of fine wool Super Merino (SM) and coarse wool Small Tail Han (STH) sheep. SM sheep had a…”
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Epithelial, metabolic and innate immunity transcriptomic signatures differentiating the rumen from other sheep and mammalian gastrointestinal tract tissues by Xiang, Ruidong, Oddy, Victor Hutton, Archibald, Alan L, Vercoe, Phillip E, Dalrymple, Brian P

“…Background. Ruminants are successful herbivorous mammals, in part due to their specialized forestomachs, the rumen complex, which facilitates the conversion of…”
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Inferring the Transcriptional Landscape of Bovine Skeletal Muscle by Integrating Co-Expression Networks by Hudson, Nicholas J, Reverter, Antonio, Wang, YongHong, Greenwood, Paul L, Dalrymple, Brian P

“…Background: Despite modern technologies and novel computational approaches, decoding causal transcriptional regulation remains challenging. This is…”
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Gene network analysis identifies rumen epithelial cell proliferation, differentiation and metabolic pathways perturbed by diet and correlated with methane production by Xiang, Ruidong, McNally, Jody, Rowe, Suzanne, Jonker, Arjan, Pinares-Patino, Cesar S., Oddy, V. Hutton, Vercoe, Phil E., McEwan, John C., Dalrymple, Brian P.

“…Ruminants obtain nutrients from microbial fermentation of plant material, primarily in their rumen, a multilayered forestomach. How the different layers of the…”
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Porcine tissue-specific regulatory networks derived from meta-analysis of the transcriptome by Pérez-Montarelo, Dafne, Hudson, Nicholas J, Fernández, Ana I, Ramayo-Caldas, Yuliaxis, Dalrymple, Brian P, Reverter, Antonio

“…The processes that drive tissue identity and differentiation remain unclear for most tissue types. So are the gene networks and transcription factors (TF)…”
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A divergent Artiodactyl MYADM-like repeat is associated with erythrocyte traits and weight of lamb weaned in domestic sheep by Gonzalez, Michael V, Mousel, Michelle R, Herndon, David R, Jiang, Yu, Dalrymple, Brian P, Reynolds, James O, Johnson, Wendell C, Herrmann-Hoesing, Lynn M, White, Stephen N

“…A genome-wide association study (GWAS) was performed to investigate seven red blood cell (RBC) phenotypes in over 500 domestic sheep (Ovis aries) from three…”
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Genome-wide patterns of promoter sharing and co-expression in bovine skeletal muscle by Gu, Quan, Nagaraj, Shivashankar H, Hudson, Nicholas J, Dalrymple, Brian P, Reverter, Antonio

“…Gene regulation by transcription factors (TF) is species, tissue and time specific. To better understand how the genetic code controls gene expression in…”
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Origin, Evolution, and Biological Role of miRNA Cluster in DLK-DIO3 Genomic Region in Placental Mammals by Glazov, Evgeny A., McWilliam, Sean, Barris, Wesley C., Dalrymple, Brian P.

“…MicroRNAs (miRNAs) are a rapidly growing family of small regulatory RNAs modulating gene expression in plants and animals. In animals, most of the miRNAs…”
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A gene expression estimator of intramuscular fat percentage for use in both cattle and sheep by Guo, Bing, Kongsuwan, Kritaya, Greenwood, Paul L, Zhou, Guanghong, Zhang, Wangang, Dalrymple, Brian P

“…Background：The expression of genes encoding proteins involved in triacyglyceride and fatty acid synthesis and storage in cattle muscle are correlated with…”
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Modes of genetic adaptations underlying functional innovations in the rumen by Pan, Xiangyu, Cai, Yudong, Li, Zongjun, Chen, Xianqing, Heller, Rasmus, Wang, Nini, Wang, Yu, Zhao, Chen, Wang, Yong, Xu, Han, Li, Songhai, Li, Ming, Li, Cunyuan, Hu, Shengwei, Li, Hui, Wang, Kun, Chen, Lei, Wei, Bin, Zheng, Zhuqing, Fu, Weiwei, Yang, Yue, Zhang, Tingting, Hou, Zhuoting, Yan, Yueyang, Lv, Xiaoyang, Sun, Wei, Li, Xinyu, Huang, Shisheng, Liu, Lixiang, Mao, Shengyong, Liu, Wenqing, Hua, Jinlian, Li, Zhipeng, Zhang, Guojie, Chen, Yulin, Wang, Xihong, Qiu, Qiang, Dalrymple, Brian P., Wang, Wen, Jiang, Yu

“…The rumen is the hallmark organ of ruminants and hosts a diverse ecosystem of microorganisms that facilitates efficient digestion of plant fibers. We analyzed…”
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Mammalian genomic regulatory regions predicted by utilizing human genomics, transcriptomics, and epigenetics data by Nguyen, Quan H, Tellam, Ross L, Naval-Sanchez, Marina, Porto-Neto, Laercio R, Barendse, William, Reverter, Antonio, Hayes, Benjamin, Kijas, James, Dalrymple, Brian P

“…Genome sequences for hundreds of mammalian species are available, but an understanding of their genomic regulatory regions, which control gene expression, is…”
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A Universal Protein-Protein Interaction Motif in the Eubacterial DNA Replication and Repair Systems by Dalrymple, Brian P., Kongsuwan, Kritaya, Wijffels, Gene, Dixon, Nicholas E., Jennings, Philip A.

“…The interaction between DNA polymerases and sliding clamp proteins confers processivity in DNA synthesis. This interaction is critical for most DNA replication…”
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