Search Results - "DALEY, P"

CRISPR-mediated live imaging of genome editing and transcription by Wang, Haifeng, Nakamura, Muneaki, Abbott, Timothy R, Zhao, Dehua, Luo, Kaiwen, Yu, Cordelia, Nguyen, Cindy M, Lo, Albert, Daley, Timothy P, La Russa, Marie, Liu, Yanxia, Qi, Lei S

“…We report a robust, versatile approach called CRISPR live-cell fluorescent in situ hybridization (LiveFISH) using fluorescent oligonucleotides for genome…”
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Extracellular matrix dynamics in development and regenerative medicine by Daley, William P, Peters, Sarah B, Larsen, Melinda

“…The extracellular matrix (ECM) regulates cell behavior by influencing cell proliferation, survival, shape, migration and differentiation. Far from being a…”
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Patterned cell and matrix dynamics in branching morphogenesis by Wang, Shaohe, Sekiguchi, Rei, Daley, William P, Yamada, Kenneth M

“…Many embryonic organs undergo branching morphogenesis to maximize their functional epithelial surface area. Branching morphogenesis requires the coordinated…”
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A benchmark of algorithms for the analysis of pooled CRISPR screens by Bodapati, Sunil, Daley, Timothy P, Lin, Xueqiu, Zou, James, Qi, Lei S

“…Genome-wide pooled CRISPR-Cas-mediated knockout, activation, and repression screens are powerful tools for functional genomic investigations. Despite their…”
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CRISPhieRmix: a hierarchical mixture model for CRISPR pooled screens by Daley, Timothy P, Lin, Zhixiang, Lin, Xueqiu, Liu, Yanxia, Wong, Wing Hung, Qi, Lei S

“…Pooled CRISPR screens allow researchers to interrogate genetic causes of complex phenotypes at the genome-wide scale and promise higher specificity and…”
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GEMINI: a variational Bayesian approach to identify genetic interactions from combinatorial CRISPR screens by Zamanighomi, Mahdi, Jain, Sidharth S, Ito, Takahiro, Pal, Debjani, Daley, Timothy P, Sellers, William R

“…Systems for CRISPR-based combinatorial perturbation of two or more genes are emerging as powerful tools for uncovering genetic interactions. However,…”
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RIP1 suppresses innate immune necrotic as well as apoptotic cell death during mammalian parturition by Kaiser, William J., Daley-Bauer, Lisa P., Thapa, Roshan J., Mandal, Pratyusha, Berger, Scott B., Huang, Chunzi, Sundararajan, Aarthi, Guo, Hongyan, Roback, Linda, Speck, Samuel H., Bertin, John, Gough, Peter J., Balachandran, Siddharth, Mocarski, Edward S.

“…The pronecrotic kinase, receptor interacting protein (RIP1, also called RIPK1) mediates programmed necrosis and, together with its partner, RIP3 (RIPK3),…”
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Surotomycin versus vancomycin in adults with Clostridium difficile infection: primary clinical outcomes from the second pivotal, randomized, double-blind, Phase 3 trial by Daley, P, Louie, T, Lutz, J E, Khanna, S, Stoutenburgh, U, Jin, M, Adedoyin, A, Chesnel, L, Guris, D, Larson, K B, Murata, Y

“…The available treatment options for Clostridium difficile infection (CDI) are limited by high recurrence rates. Surotomycin was a novel bactericidal cyclic…”
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Viral immunity: Basic mechanisms and therapeutic applications—a Keystone Symposia report by Cable, Jennifer, Balachandran, Siddharth, Daley‐Bauer, Lisa P., Rustagi, Arjun, Antony, Ferrin, Frere, Justin J., Strampe, Jamie, Kedzierska, Katherine, Cannon, Judy L., McGargill, Maureen A., Weiskopf, Daniela, Mettelman, Robert C., Niessl, Julia, Thomas, Paul G., Briney, Bryan, Valkenburg, Sophie A., Bloom, Jesse D., Bjorkman, Pamela J., Iketani, Sho, Rappazzo, C. Garrett, Crooks, Chelsea M., Crofts, Kali F., Pöhlmann, Stefan, Krammer, Florian, Sant, Andrea J., Nabel, Gary J., Schultz‐Cherry, Stacey

“…Viruses infect millions of people each year. Both endemic viruses circulating throughout the population as well as novel epidemic and pandemic viruses pose…”
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Cytomegalovirus Impairs Antiviral CD8+ T Cell Immunity by Recruiting Inflammatory Monocytes by Daley-Bauer, Lisa P., Wynn, Grace M., Mocarski, Edward S.

“…Inflammatory monocytes are key early responders to infection that contribute to pathogen-host interactions in diverse ways. Here, we report that the murine…”
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Mesenchymal stromal cells in hematopoietic cell transplantation by Burnham, Andre J., Daley-Bauer, Lisa P., Horwitz, Edwin M.

“…Mesenchymal stromal cells (MSCs) are widely recognized to possess potent immunomodulatory activity, as well as to stimulate repair and regeneration of diseased…”
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Evaluation of the Precision of Kinetic Stem Cell (KSC) Counting for Specific Quantification of Human Mesenchymal Stem Cells in Heterogeneous Tissue Cell Preparations by Chopra, Hitesh, Daley, Michael P, Kumar, Adhya, Sugai, James, Dahlkemper, Alex, Kaigler, Darnell, Sherley, James L

“…Kinetic stem cell (KSC) counting is a recently introduced first technology for quantifying tissue stem cells in vertebrate organ and tissue cell preparations…”
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True grit: programmed necrosis in antiviral host defense, inflammation, and immunogenicity by Mocarski, Edward S, Kaiser, William J, Livingston-Rosanoff, Devon, Upton, Jason W, Daley-Bauer, Lisa P

“…Programmed necrosis mediated by receptor interacting protein kinase (RIP)3 (also called RIPK3) has emerged as an alternate death pathway triggered by TNF…”
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Henoch–Schönlein purpura in the setting of COVID-19 infection: Two pediatrics cases and review of the literature by Zumbro, Caleb, Davidson, Samuel, Daley, William, Camacho, Sandra

“…Henoch–Schönlein purpura (HSP) is the most common systemic vasculitis in children, often following a viral infection. Various types of rashes attributed to…”
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Identification of a mechanochemical checkpoint and negative feedback loop regulating branching morphogenesis by Daley, William P., Gulfo, Kathryn M., Sequeira, Sharon J., Larsen, Melinda

“…Cleft formation is the initial step in submandibular salivary gland (SMG) branching morphogenesis, and may result from localized actomyosin-mediated cellular…”
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Risk of bias and limits of reporting in diagnostic accuracy studies for commercial point-of-care tests for respiratory pathogens by Hughes, J.M., Penney, C., Boyd, S., Daley, P.

“…Commercial point-of-care (POC) diagnostic tests for Group A Streptococcus, Streptococcus pneumoniae, and influenza virus have large potential diagnostic and…”
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RIP3 mediates the embryonic lethality of caspase-8-deficient mice by Kaiser, William J., Upton, Jason W., Long, Alyssa B., Livingston-Rosanoff, Devon, Daley-Bauer, Lisa P., Hakem, Razqallah, Caspary, Tamara, Mocarski, Edward S.

“…Caspase-8 joins RIPK at the death Caspase-8 mediates apoptosis induced by 'death receptors' on the cell's surface. At the same time, it is able to prevent…”
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ROCK1-directed basement membrane positioning coordinates epithelial tissue polarity by Daley, William P, Gervais, Elise M, Centanni, Samuel W, Gulfo, Kathryn M, Nelson, Deirdre A, Larsen, Melinda

“…The basement membrane is crucial for epithelial tissue organization and function. However, the mechanisms by which basement membrane is restricted to the basal…”
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Inhibition of tumorigenesis driven by different Wnt proteins requires blockade of distinct ligand-binding regions by LRP6 antibodies by Ettenberg, Seth A., Charlat, Olga, Daley, Michael P., Liu, Shanming, Vincent, Karen J., Stuart, Darrin D., Schuller, Alwin G., Yuan, Jing, Ospina, Beatriz, Green, John, Yu, Qunyan, Walsh, Renee, Li, Sharon, Schmitz, Rita, Heine, Holger, Bilic, Sanela, Ostrom, Lance, Mosher, Rebecca, Hartlepp, K. Felix, Zhu, Zhenping, Fawell, Stephen, Yao, Yung-Mae, Stover, David, Finan, Peter M., Porter, Jeffery A., Sellers, William R., Klagge, Ingo M., Cong, Feng, Nusse, Roeland

“…Disregulated Wnt/β-catenin signaling has been linked to various human diseases, including cancers. Inhibitors of oncogenic Wnt signaling are likely to have a…”
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Novel tests for diagnosing tuberculous pleural effusion: what works and what does not? by Trajman, A, Pai, M, Dheda, K, van Zyl Smit, R, Zwerling, A. A, Joshi, R, Kalantri, S, Daley, P, Menzies, D

“…Tuberculous pleuritis is a common manifestation of extrapulmonary tuberculosis and is the most common cause of pleural effusion in many countries. Conventional…”
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