Search Results - "DALEMANS, W."

Improved Immunogenicity and Protective Efficacy of a Tuberculosis DNA Vaccine Encoding Ag85 by Protein Boosting by TANGHE, Audrey, D'SOUZA, Sushila, ROSSEELS, Valérie, DENIS, Olivier, OTTENHOFF, Thomas H. M, DALEMANS, Wilfried, WHEELER, Carl, HUYGEN, Kris

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Insect cells as a new substrate for vaccine production by Dalemans, W

“…Vaccine antigens can be expressed in several expression systems, of which expression in eukaryotic cell lines is a well-known example. Whereas for most current…”
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In vitro cellular immune responses to complex and newly defined recombinant antigens of Mycobacterium tuberculosis by AL‐ATTIYAH, R., MUSTAFA, A. S., ABAL, A. T., EL‐SHAMY, A. S. M., DALEMANS, W., SKEIKY, Y. A. W.

“…SUMMARY The immunological diagnosis and development of new antituberculosis vaccines require the characterization of Mycobacterium tuberculosis antigens…”
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Prospects for a better vaccine against tuberculosis by Reed, S.G., Alderson, M.R., Dalemans, W., Lobet, Y., Skeiky, Y.A.W.

“…There have been many new promising approaches to developing human vaccines against tuberculosis (TB). Advances in gene and antigen identification, availability…”
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Intra-pinna anti-tumor vaccination with self-replicating infectious RNA or with DNA encoding a model tumor antigen and a cytokine by SCHIRRMACHER, V, FÖRG, P, DALEMANS, W, CHLICHLIA, K, ZENG, Y, FOURNIER, P, VON HOEGEN, P

“…To optimize polynucleotide vaccinations for protective antitumor immunity we used a self-replicating RNA vaccine in which Semliki Forest virus replicase drives…”
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The cystic fibrosis gene has a "housekeeping"-type promoter and is expressed at low levels in cells of epithelial origin by YOSHIMURA, K, NAKAMURA, H, TRAPNELL, B. C, DALEMANS, W, PAVIRANI, A, LECOCQ, J.-P, CRYSTAL, R. G

“…Evaluation of the expression of the cystic fibrosis (CF) gene in human epithelial cell lines demonstrated active, but low level, transcription of the gene…”
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Expression of the cystic fibrosis transmembrane conductance regulator gene in cells of non-epithelial origin by YOSHIMURA, K, NAKAMURA, H, TRAPNELL, B. C, CHIN-SHYAN CHU, DALEMANS, W. D, PAVIRANI, A, LECOCQ, J.-P, CRYSTAL, R. G

“…Consistent with the fact that the clinical disorder cystic fibrosis (CF) is manifested on epithelial surfaces, active transcription of the CF transmembrane…”
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Localization of the cystic fibrosis transmembrane conductance regulator in airway secretory glands by Jacquot, J, Puchelle, E, Hinnrasky, J, Fuchey, C, Bettinger, C, Spilmont, C, Bonnet, N, Dieterle, A, Dreyer, D, Pavirani, A

“…Cystic fibrosis (CF) is caused by mutations in the gene coding for the CF transmembrane conductance regulator (CFTR). From human normal tracheal submucosal…”
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Differential localization of the cystic fibrosis transmembrane conductance regulator in normal and cystic fibrosis airway epithelium by Puchelle, E, Gaillard, D, Ploton, D, Hinnrasky, J, Fuchey, C, Boutterin, M C, Jacquot, J, Dreyer, D, Pavirani, A, Dalemans, W

“…Deletion of the amino acid residue Phe 508 of the cystic fibrosis transmembrane conductance regulator (CFTR) protein represents the most common mutation…”
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Autocrine mitogen IgEGF cooperates with c-myc or with the Hcs locus during hepatocarcinogenesis in transgenic mice by Tönjes, R R, Löhler, J, O'Sullivan, J F, Kay, G F, Schmidt, G H, Dalemans, W, Pavirani, A, Paul, D

“…Hepatocarcinogenesis is deterministic in transgenic mice expressing in the liver gene construct Alb-DS4 that encodes autocrine growth factor IgEGF (D Stern et…”
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Down-regulation of cystic fibrosis gene mRNA transcript levels and induction of the cystic fibrosis chloride secretory phenotype in epithelial cells by phorbol ester by TRAPNELL, ZEITLIN, P. L, LECOCQ, J.-P, CRYSTAL, R. G, CHIN-SHYAN CHU, YOSHIMURA, K, NAKAMURA, H, GUGGINO, W. B, BARGON, J, BANKS, T. C, DALEMANS, W, PAVIRANI, A

“…To evaluate the hypothesis that phorbol myristate acetate (PMA) might modulate the expression of the cystic fibrosis (CF) gene in epithelial cells, we examined…”
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Variable deletion of exon 9 coding sequences in cystic fibrosis transmembrane conductance regulator gene mRNA transcripts in normal bronchial epithelium by CHIN-SHYAN CHU, TRAPNELL, B. C, GUGGINO, W. B, CRYSTAL, R. G, MURTAGH, J. J, MOSS, J, DALEMANS, W, JALLAT, S, MERCENIER, A, PAVIRANI, A, LECOCQ, J.-P, CUTTING, G. R

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A change in gating mode leading to increased intrinsic Cl‐ channel activity compensates for defective processing in a cystic fibrosis mutant corresponding to a mild form of the disease by Champigny, G., Imler, J.L., Puchelle, E., Dalemans, W., Gribkoff, V., Hinnrasky, J., Dott, K., Barbry, P., Pavirani, A., Lazdunski, M.

“…The effects of the mild cystic fibrosis (CF) mutation P574H were analysed and compared with those of three severe ones (delta I507, delta F508 and R560T)…”
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Characterization of recombinant human factor IX expressed in transgenic mice and in derived trans‐immortalized hepatic cell lines by Jallat, S., Perraud, F., Dalemans, W., Balland, A., Dieterle, A., Faure, T., Meulien, P., Pavirani, A.

“…Transgenic mice were generated in which 5 kb of the 5′ flanking promoter region of the human Factor IX (FIX) gene fused to various FIX constructs (gene,…”
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Protection against homologous influenza challenge by genetic immunization with SFV-RNA encoding Flu-HA by Dalemans, W, Delers, A, Delmelle, C, Denamur, F, Meykens, R, Thiriart, C, Veenstra, S, Francotte, M, Bruck, C, Cohen, J

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Differential Immune Responses and Protective Efficacy Induced by Components of a Tuberculosis Polyprotein Vaccine, Mtb72F, Delivered as Naked DNA or Recombinant Protein by Skeiky, Yasir A. W, Alderson, Mark R, Ovendale, Pamela J, Guderian, Jeffrey A, Brandt, Lise, Dillon, Davin C, Campos-Neto, Antonio, Lobet, Yves, Dalemans, Wilfried, Orme, Ian M, Reed, Steven G

“…Key Ags of Mycobacterium tuberculosis initially identified in the context of host responses in healthy purified protein derivative-positive donors and infected…”
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Protection of macaques against Mycobacterium tuberculosis infection by a subunit vaccine based on a fusion protein of antigen 85B and ESAT-6 by Langermans, Jan A.M., Doherty, T. Mark, Vervenne, Richard A.W., Laan, Tridia van der, Lyashchenko, Konstantin, Greenwald, Rena, Agger, Else Marie, Aagaard, Claus, Weiler, Horst, Soolingen, Dick van, Dalemans, Wilfried, Thomas, Alan W., Andersen, Peter

“…Various new tuberculosis (TB) vaccine candidates in combination with new delivery systems, including subunit vaccines, are currently being evaluated by a…”
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Expression of the cystic fibrosis transmembrane conductance regulator gene can be regulated by protein kinase C by BARGON, J, TRAPNELL, B. C, YOSHIMURA, K, DALEMANS, W, PAVIRANI, A, LECOCQ, J.-P, CRYSTAL, R. G

“…Epithelial cells utilize at least two types of apical Cl- channels, the cAMP-activated cystic fibrosis transmembrane conductance regulator (CFTR) and the…”
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White paper on how to go forward with cell-based advanced therapies in Europe by Erben, Reinhold G, Silva-Lima, Beatriz, Reischl, Ilona, Steinhoff, Gustav, Tiedemann, Gudrun, Dalemans, Wilfried, Vos, Alexander, Janssen, Rob T A, Le Blanc, Katarina, van Osch, Gerjo J V M, Luyten, Frank P

“…The current White paper summarizes the discussions and exchange of experiences during the first European Interdisciplinary Summit on Cell-Based ATMPs held in…”
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The Protective Effect of the Mycobacterium bovis BCG Vaccine Is Increased by Coadministration with the Mycobacterium tuberculosis 72-Kilodalton Fusion Polyprotein Mtb72F in M. tuberculosis-Infected Guinea Pigs by BRANDT, Lise, SKEIKY, Yasir A. W, REED, Steven G, ORME, Ian M, ALDERSON, Mark R, LOBET, Yves, DALEMANS, Wilfried, TURNER, Oliver C, BASARABA, Randall J, IZZO, Angelo A, LASCO, Todd M, CHAPMAN, Philip L

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