Search Results - "DAL MONTE, M"
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Mitigation of human iris angiogenesis through uPAR/LRP‐1 interaction antagonism in an organotypic ex vivo model
Published in The FASEB journal (15-03-2024)“…Rubeosis Iridis (RI) is characterized by an increase in neovascularization and inflammation factors in the iris. During angiogenesis, the urokinase plasminogen…”
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2
An imbalance in autophagy contributes to retinal damage in a rat model of oxygen‐induced retinopathy
Published in Journal of cellular and molecular medicine (01-11-2021)“…In retinopathy of prematurity (ROP), the abnormal retinal neovascularization is often accompanied by retinal neuronal dysfunction. Here, a rat model of…”
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The Urokinase Receptor-Derived Peptide UPARANT Mitigates Angiogenesis in a Mouse Model of Laser-Induced Choroidal Neovascularization
Published in Investigative ophthalmology & visual science (01-05-2016)“…A mouse model of age-related macular degeneration (AMD) was used to investigate the anti-angiogenic and anti-inflammatory role of UPARANT in laser-induced…”
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Gaining insight on mitigation of rubeosis iridis by UPARANT in a mouse model associated with proliferative retinopathy
Published in Journal of molecular medicine (Berlin, Germany) (01-11-2020)“…Proliferative retinopathies (PR) lead to an increase in neovascularization and inflammation factors, at times culminating in pathologic rubeosis iridis (RI)…”
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UPARANT is an effective antiangiogenic agent in a mouse model of rubeosis iridis
Published in Journal of molecular medicine (Berlin, Germany) (01-09-2019)“…Puncture-induced iris neovascularization (rubeosis iridis; RI) in mice is associated with upregulation of extracellular matrix (ECM) degradation and…”
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Nebivolol acts as a beta3‐adrenergic receptor agonist in a mouse model of oxygen‐induced retinopathy
Published in Acta ophthalmologica (Oxford, England) (01-09-2017)“…Purpose Nebivolol is a β1‐adrenergic receptor (AR) antagonist with vasodilatory properties. Nebivolol, but not the β1‐AR antagonist atenolol, has been found to…”
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Pyrroloquinoline quinone drives ATP synthesis in vitro and in vivo and provides retinal ganglion cell neuroprotection
Published in Acta neuropathologica communications (08-09-2023)“…Abstract Retinal ganglion cells are highly metabolically active requiring strictly regulated metabolism and functional mitochondria to keep ATP levels in…”
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Functionalized magnetic nanoparticles as a novel strategy for the treatment of diabetic retinopathy
Published in Acta ophthalmologica (Oxford, England) (01-09-2017)“…Purpose Neuroprotection‐based strategies may be exploited to treat diabetic retinopathy (DR). Our aim is to establish a method for magnetic nanoparticle…”
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Neural degeneration mechanisms in diabetic retinopathy: The role of apoptosis and autophagy
Published in Acta ophthalmologica (Oxford, England) (01-09-2017)“…Purpose That neuronal injury plays a major role in diabetic retinopathy (DR) is gaining increasing recognition. In particular, we have recently shown, using an…”
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Neurokinin 1 receptor expression and substance p physiological actions are developmentally regulated in the rabbit retina
Published in Neuroscience (2004)“…We investigated the expression of the substance P (SP) receptor (the neurokinin 1 receptor, NK1 receptor) and SP functional effects in developing rabbit…”
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Efficacy of a Fatty Acids Dietary Supplement in a Polyethylene Glycol-Induced Mouse Model of Retinal Degeneration
Published in Nutrients (29-09-2017)“…Current knowledge of the benefits of nutrition supplements for eye pathologies is based largely on the use of appropriate animal models, together with defined…”
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Autophagy Involvement in the Postnatal Development of the Rat Retina
Published in Cells (Basel, Switzerland) (01-01-2021)“…During retinal development, a physiologic hypoxia stimulates endothelial cell proliferation. The hypoxic milieu warrants retina vascularization and promotes…”
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Neuroprotection as a therapeutic target in diabetic retinopathy: a basic approach
Published in Acta ophthalmologica (Oxford, England) (01-10-2015)“…Purpose To test the hypothesis that protecting retinal neurons from apoptosis elicited by diabetic stress may prevent the increase of vascular endothelial…”
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Propranolol concentrations after oral administration in term and preterm neonates
Published in The journal of maternal-fetal & neonatal medicine (01-05-2013)“…Abstract Objective: While propranolol pharmacokinetics has been extensively studied in adults, this study reports the first evaluation of propranolol…”
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Expression of neuropeptides and their receptors in the developing retina of mammals
Published in Histology and histopathology (01-10-2003)“…The present review examines various aspects of the developmental expression of neuropeptides and of their receptors in mammalian retinas, emphasizing their…”
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Functional aspects of the somatostatinergic system in the retina and the potential therapeutic role of somatostatin in retinal disease
Published in Histology and histopathology (01-04-2005)“…The somatostatinergic system of the retina has been investigated in a variety of studies. A considerable amount of experimental evidence is available…”
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Influence of genotype on physico-mechanical characteristics of goat and sheep leather
Published in Small ruminant research (01-11-2007)“…Increasing attention to the quality of skins has been paid by the goat and sheep production industries in Brazil, since the skin might represent a great…”
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Expression of substance P, neurokinin 1 receptors (NK1) and neurokinin 3 receptors in the developing mouse retina and in the retina of NK1 knockout mice
Published in Neuroscience (2006)“…To complete a series of studies on the expression of substance P and neurokinin receptors in mammalian retinas, we investigated the occurrence of these…”
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Physiological Thiols as Promoters of Glutathione Oxidation and Modifying Agents in Protein S-Thiolation
Published in Archives of biochemistry and biophysics (15-01-2002)“…Glutathione is one of the most relevant antioxidants present in cells. It exerts its scavenging action through the involvement of efficient and ubiquitous…”
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Thiol/Disulfide Interconversion in Bovine Lens Aldose Reductase Induced by Intermediates of Glutathione Turnover
Published in Biochemistry (Easton) (09-10-2001)“…The effectiveness of cysteine and cysteinylglycine to act as protein thiolating agents was investigated using bovine lens aldose reductase (ALR2) as the…”
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