Search Results - "DAHLIN, S"

PAGA: graph abstraction reconciles clustering with trajectory inference through a topology preserving map of single cells by Wolf, F Alexander, Hamey, Fiona K, Plass, Mireya, Solana, Jordi, Dahlin, Joakim S, Göttgens, Berthold, Rajewsky, Nikolaus, Simon, Lukas, Theis, Fabian J

“…Single-cell RNA-seq quantifies biological heterogeneity across both discrete cell types and continuous cell transitions. Partition-based graph abstraction…”
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A single-cell hematopoietic landscape resolves 8 lineage trajectories and defects in Kit mutant mice by Dahlin, Joakim S., Hamey, Fiona K., Pijuan-Sala, Blanca, Shepherd, Mairi, Lau, Winnie W.Y., Nestorowa, Sonia, Weinreb, Caleb, Wolock, Samuel, Hannah, Rebecca, Diamanti, Evangelia, Kent, David G., Göttgens, Berthold, Wilson, Nicola K.

“…Hematopoietic stem and progenitor cells (HSPCs) maintain the adult blood system, and their dysregulation causes a multitude of diseases. However, the…”
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A single-cell map of vascular and tissue lymphocytes identifies proliferative TCF-1+ human innate lymphoid cells by Gao, Yu, Alisjahbana, Arlisa, Boey, Daryl Zhong Hao, Mohammad, Imran, Sleiers, Natalie, Dahlin, Joakim S., Willinger, Tim

“…Innate lymphoid cells (ILCs) play important roles in tissue homeostasis and host defense, but the proliferative properties and migratory behavior of especially…”
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Single‐cell molecular profiling provides a high‐resolution map of basophil and mast cell development by Hamey, Fiona K., Lau, Winnie W.Y., Kucinski, Iwo, Wang, Xiaonan, Diamanti, Evangelia, Wilson, Nicola K., Göttgens, Berthold, Dahlin, Joakim S.

“…Background Basophils and mast cells contribute to the development of allergic reactions. Whereas these mature effector cells are extensively studied, the…”
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Systemic mastocytosis: dying or survivin by Dahlin, Joakim S., Nilsson, Gunnar

“…In this issue of Blood , Greiner et al 1 demonstrate that aberrant mast cells in systemic mastocytosis with the KIT D816V mutation release tumor necrosis…”
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The ingenious mast cell: Contemporary insights into mast cell behavior and function by Dahlin, Joakim S., Maurer, Marcus, Metcalfe, Dean D., Pejler, Gunnar, Sagi‐Eisenberg, Ronit, Nilsson, Gunnar

“…Mast cells are (in)famous for their role in allergic diseases, but the physiological and pathophysiological roles of this ingenious cell are still not fully…”
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Distinguishing Mast Cell Progenitors from Mature Mast Cells in Mice by Dahlin, Joakim S, Ding, Zhoujie, Hallgren, Jenny

“…Mast cells originate from the bone marrow and develop into c-kit(+) FcɛRI(+) cells. Both mast cell progenitors (MCp) and mature mast cells express these cell…”
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N₂ fixation, N transfer, and yield in grassland communities including a deep-rooted legume or non-legume species by Frankow-Lindberg, B. E., Dahlin, A. S.

“…Background and aims Legumes are important components of grassland mixtures due to their ability to sustain high yields with moderate nitrogen inputs. This…”
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Committed mast cell progenitors in mouse blood differ in maturity between Th1 and Th2 strains by Dahlin, J. S., Heyman, B., Hallgren, J.

“…Mast cell progenitors (MCp) leave the bone marrow and migrate to peripheral tissues where they mature. Although the existence of committed MCp in adult mouse…”
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New insights into the origin of mast cells by Nilsson, Gunnar, Dahlin, Joakim S.

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Charting hematopoiesis in the single-cell omics era by Boey, Daryl, Nilsson, Gunnar, Dahlin, Joakim S.

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Immunoprofiling Reveals Novel Mast Cell Receptors and the Continuous Nature of Human Lung Mast Cell Heterogeneity by Rönnberg, Elin, Boey, Daryl Zhong Hao, Ravindran, Avinash, Säfholm, Jesper, Orre, Ann-Charlotte, Al-Ameri, Mamdoh, Adner, Mikael, Dahlén, Sven-Erik, Dahlin, Joakim S, Nilsson, Gunnar

“…Immunohistochemical analysis of granule-associated proteases has revealed that human lung mast cells constitute a heterogeneous population of cells, with…”
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Localization-Specific Expression of CCR1 and CCR5 by Mast Cell Progenitors by Salomonsson, Maya, Dahlin, Joakim S, Ungerstedt, Johanna, Hallgren, Jenny

“…Mast cells are powerful immune cells found predominately in barrier tissues. They play an important role in immune surveillance and act as effector cells in…”
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Maternal tobacco use and extremely premature birth – a population‐based cohort study by Dahlin, S, Gunnerbeck, A, Wikström, A‐K, Cnattingius, S, Edstedt Bonamy, A‐K

“…Objective To study the associations of maternal tobacco use (smoking or use of snuff) and risk of extremely preterm birth, and if tobacco cessation before…”
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Deciphering the differentiation trajectory from hematopoietic stem cells to mast cells by Grootens, Jennine, Ungerstedt, Johanna S., Nilsson, Gunnar, Dahlin, Joakim S.

“…Hematopoietic stem cells differentiate into all types of blood cells, including peripheral tissue-resident mast cells. The early mast cell differentiation…”
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Analysis of human lung mast cells by single cell RNA sequencing by Rönnberg, Elin, Ravindran, Avinash, Mazzurana, Luca, Gong, Yitao, Säfholm, Jesper, Lorent, Julie, Dethlefsen, Olga, Orre, Ann-Charlotte, Al-Ameri, Mamdoh, Adner, Mikael, Dahlén, Sven-Erik, Dahlin, Joakim S, Mjösberg, Jenny, Nilsson, Gunnar

“…Mast cells are tissue-resident cells playing major roles in homeostasis and disease conditions. Lung mast cells are particularly important in airway…”
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An Optimized Protocol for the Isolation and Functional Analysis of Human Lung Mast Cells by Ravindran, Avinash, Rönnberg, Elin, Dahlin, Joakim S, Mazzurana, Luca, Säfholm, Jesper, Orre, Ann-Charlotte, Al-Ameri, Mamdoh, Peachell, Peter, Adner, Mikael, Dahlén, Sven-Erik, Mjösberg, Jenny, Nilsson, Gunnar

“…Mast cells are tissue-resident inflammatory cells defined by their high granularity and surface expression of the high-affinity IgE receptor, FcεRI, and…”
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Proteomic and transcriptomic screening demonstrates increased mast cell–derived CCL23 in systemic mastocytosis by Söderlund, Stina, Boey, Daryl, van Midden, Wouter, Kjellander, Matilda, Ax, Kajsa, Qian, Hong, Dahlin, Joakim S., Ungerstedt, Johanna

“…[Display omitted] Systemic mastocytosis (SM) is a heterogeneous group of mast cell–driven diseases diagnosed by bone marrow sampling. However, there are a…”
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KIT signaling is dispensable for human mast cell progenitor development by Dahlin, Joakim S., Ekoff, Maria, Grootens, Jennine, Löf, Liza, Amini, Rose-Marie, Hagberg, Hans, Ungerstedt, Johanna S., Olsson-Strömberg, Ulla, Nilsson, Gunnar

“…Human hematopoietic progenitors are generally assumed to require stem cell factor (SCF) and KIT signaling during differentiation for the formation of mast…”
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CD11c+ cells are required for antigen-induced increase of mast cells in the lung by Dahlin, Joakim S, Feinstein, Ricardo, Cui, Yue, Heyman, Birgitta, Hallgren, Jenny

“…Patients with allergic asthma have more lung mast cells, which likely worsens the symptoms. In experimental asthma, CD11c(+) cells have to be present during…”
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