Search Results - "DAGANI, F"
-
1
The mitochondrial electron transfer alteration as a factor involved in the brain aging
Published in Neurobiology of aging (01-05-1992)“…The tissutal concentrations of reduced glutathione (GSH) and the contents of some key components in the electron transfer chain (namely ubiquinone, cytochromes…”
Get more information
Journal Article -
2
Abnormal skeletal and cardiac muscle mitochondria induced by zidovudine (AZT) in human muscle in vitro and in an animal model
Published in Laboratory investigation (01-12-1991)“…To examine the mechanism of mitochondrial myocytotoxicity caused by long-term administration of zidovudine (AZT) in human immunodeficiency virus-positive…”
Get more information
Journal Article -
3
Relations between intracellular ions and energy metabolism: a study with monensin in synaptosomes, neurons, and C6 glioma cells
Published in The Journal of neuroscience (01-08-1991)“…Treatment of rat brain synaptosomes with 10 microM monensin stimulated activity of the Na/K pump, which enhanced oxygen consumption and lactate production…”
Get full text
Journal Article -
4
Sequential damage in mitochondrial complexes by peroxidative stress
Published in Neurochemical research (01-12-1991)“…The biochemical characteristics of the electron transfer chain are evaluated in purified non-synaptic ("free") mitochondria from the forebrain of 60-week-old…”
Get full text
Journal Article -
5
No evidence for altered muscle mitochondrial function in Parkinson's disease
Published in Journal of neurology, neurosurgery and psychiatry (01-05-1993)“…Recent reports indicate that reductions in mitochondrial respiratory chain function occur in substantia nigra, platelets, and muscle from patients with…”
Get full text
Journal Article -
6
Effect of aging and acetyl-L-carnitine on energetic and cholinergic metabolism in rat brain regions
Published in Mechanisms of ageing and development (01-01-1989)“…The effect of aging and subchronic treatment with acetyl-L-carnitine (50 mg/kg per day) was studied on mitochondrial bioenergetics and cholinergic metabolism…”
Get more information
Journal Article -
7
Glutamate metabolism, release, and quantal transmission at central excitatory synapses: implications for neural plasticity
Published in Functional neurology (01-07-1992)“…Glutamate is thought to act as a neurotransmitter at several excitatory synapses in the brain. Available knowledge reveals complex intercompartmental dynamics…”
Get more information
Journal Article -
8
Biochemical evaluations in skeletal muscles of primates with MPTP parkinson-like syndrome
Published in Pharmacological research (01-06-1995)“…The toxic effects of the neurotoxin MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) in primates can be exploited for investigating the physiopathology of…”
Get full text
Journal Article -
9
Is the Mg(2+)-ATP-dependent proton pumping activity of the synaptic vesicles a factor involved in the cerebral hypoxia?
Published in Neurochemical research (01-01-1996)“…The changes in the Mg(2+)-dependent V-type ATPase activity and the Mg(2+)-ATP-dependent H+ pumping activity of the synaptic vesicles from the cerebral cortex…”
Get full text
Journal Article -
10
Oxidative metabolism of nonsynaptic mitochondria isolated from rat brain hippocampus: a comparative regional study
Published in Journal of neurochemistry (01-04-1988)“…Nonsynaptic mitochondria isolated from rat brain hippocampus were compared with those obtained by means of the same preparative procedure from cerebral cortex…”
Get more information
Journal Article -
11
Is the Mg2+-ATP-dependent proton pumping activity of the synaptic vesicles a factor involved in the cerebral hypoxia ?
Published in Neurochemical research (1996)Get full text
Conference Proceeding Journal Article -
12
Effects of diltiazem on bioenergetics, K+ gradients, and free cytosolic Ca2+ levels in rat brain synaptosomes submitted to energy metabolism inhibition and depolarization
Published in Journal of neurochemistry (01-11-1989)“…Diltiazem was able to decrease the oxygen consumption rate and lactate production in synaptosomes isolated from rat forebrains, both under control and…”
Get more information
Journal Article -
13
Influence of aging and drug treatment on the bioenergetics of hypoxic brain
Published in Neurochemical research (01-07-1990)“…Synaptosomes isolated from the forebrain of rats of different ages (20, 60 and 100 weeks of age) were incubated in Krebs-Henseleit-Hepes (pH 7.4) buffer, for…”
Get full text
Journal Article -
14
Glutamate and GABA levels in CSF from patients affected by dementia and olivo-ponto-cerebellar atrophy
Published in Acta neurologica Scandinavica (01-06-1992)“…The modifications in the CSF content of glutamate and GABA in patients afflicted with primary degenerative dementia (PDD) and olivo-ponto-cerebellar atrophy…”
Get more information
Journal Article -
15
Free mitochondria and synaptosomes from single rat forebrain. A comparison between two known subfractionation techniques
Published in Journal of neurochemistry (01-08-1985)“…Two published subcellular subfractionation techniques employing Ficoll-sucrose or sucrose-density gradient centrifugation, respectively, are evaluated for…”
Get more information
Journal Article -
16
Phenobarbital and 6-aminonicotinamide effect on cerebral enzymatic activities related to energy metabolism in different rat brain areas
Published in Neurochemical research (1987)“…The effect of phenobarbital (100 mg/kg i.p.) and 6-aminonicotinamide (6AN) (35 mg/kg i.p.) on enzyme activities related to energy transduction was investigated…”
Get full text
Journal Article -
17
Factors involved in the age-related alteration in the efficiency of the brain bioenergetics
Published in Mechanisms of ageing and development (01-11-1990)“…The synaptic energy state may be defined by the redox state of the intramitochondrial NAD-couple (delta Gox-red) and the phosphorylation state of adenine…”
Get more information
Journal Article -
18
Brain enzyme adaptation to mild normobaric intermittent hypoxia
Published in Journal of neuroscience research (1986)“…The adaptation to repeated periods of intermittent normobaric hypoxia (oxygen:nitrogen = 10:90, 12 hr daily for 5 days) of some specific enzymatic activities…”
Get more information
Journal Article -
19
Effect of prolonged and intermittent hypoxia on some cerebral enzymatic activities related to energy transduction
Published in Journal of cerebral blood flow and metabolism (01-12-1984)“…The adaptation to repeated, alternate normobaric hypoxic and normoxic exposures (12 h/day, for 5 days) and to pharmacological treatment was evaluated by…”
Get more information
Journal Article -
20
Effect of Ca2+-homopantothenate and mild hypoxia on some enzyme activities evaluated in subcellular fractions from different rat brain regions
Published in Molecular and chemical neuropathology (01-06-1989)“…The effect of Ca2+-homopantothenate (HOPA) treatment (250 mg/kg for 5 d) has been studied by evaluating the specific activity of enzymes related to: glycolytic…”
Get full text
Journal Article