Search Results - "DABBS, J. E"

Biliary excretion mechanism of CPT-11 and its metabolites in humans : Involvement of primary active transporters by CHU, X.-Y, KATO, Y, SUGIYAMA, Y, UEDA, K, SUZUKI, H, NIINUMA, K, TYSON, C. A, WEIZER, V, DABBS, J. E, FROEHLICH, R, GREEN, C. E

“…After administration of CTP-11, a camptothecin derivative exhibiting a wide spectrum of antitumor activity, dose-limiting gastrointestinal toxicity with great…”
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Oxidative DNA damage induced by potassium bromate in isolated rat renal proximal tubules and renal nuclei by Sai, K, Tyson, C A, Thomas, D W, Dabbs, J E, Hasegawa, R, Kurokawa, Y

“…Oxidative damage caused by potassium bromate (KBrO3), a rat renal carcinogen, was investigated using in vitro preparations of rat renal proximal tubules (RPT)…”
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Effects of soya bean flakes and liquorice root extract on enzyme induction and toxicity in B6C3F1 mice by Mirsalis, J C, Hamilton, C M, Schindler, J E, Green, C E, Dabbs, J E

“…Both soya bean flakes (SBF) and liquorice root extract (LRE) have previously been reported to have anticarcinogenic properties, which have been thought to be…”
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Evaluation of positive controls for the in vitro unscheduled DNA synthesis assay using hepatocytes from induced (Aroclor 1254) and uninduced male cynomolgus monkey by Hamilton, Carol M., Dabbs, Jack E., Cunningham, Glenn D., Vernetti, Lawrence A., Mirsalis, Jon C., Snyder, Ronald D.

“…We have evaluated the use of four different positive control compounds for assessing UDS in monkey hepatocytes and have found three of these,…”
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Primary active transport of organic anions on bile canalicular membrane in humans by Niinuma, K, Kato, Y, Suzuki, H, Tyson, C A, Weizer, V, Dabbs, J E, Froehlich, R, Green, C E, Sugiyama, Y

“…Biliary excretion of several anionic compounds was examined by assessing their ATP-dependent uptake in bile canalicular membrane vesicles (CMV) prepared from…”
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Metabolism and cytotoxicity of acetaminophen in hepatocytes isolated from resistant and susceptible species by Green, C E, Dabbs, J E, Tyson, C A

“…Acetaminophen (APAP) disposition was studied in vitro using hepatocytes isolated from rats, hamsters, rabbits, and dogs, species that vary markedly in…”
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Cytotoxic activity, tumor accumulation, and tissue distribution of ruthenium-103-labeled bleomycin by Stern, P H, Helpern, S E, Hagan, P L, Howell, S B, Dabbs, J E, Gordon, R M

“…Bleomycin (BLM) was labeled with gamma-emitting 103Ru. Yields of 103Ru-labeled BLM as high as 50.6% were attained. 103Ru-labeled BLM was stable in vitro and…”
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Functional integrity of isolated rat hepatocytes prepared by whole liver vs biopsy perfusion by Green, C E, Dabbs, J E, Tyson, C A

“…Isolated rat hepatocytes prepared by a newly developed, versatile biopsy perfusion method (HB cells) were compared with hepatocytes prepared by conventional…”
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The effect of certain variables on the tumor and tissue distribution of tracers V: false carrier effect, II, Fe by Hagan, P L, Halpern, S E, Stern, P H, Gordon, R M, Dabbs, J E

“…The effect of Fe3+ citrate on carrier-free 67Ga and 59Fe kinetics was studied in a Buffalo rat-Morris 7777 hepatoma model. Two mg Fe3+ citrate/Kg were…”
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Designing and Evaluating Quality of Life Technologies: An Interdisciplinary Approach: Quality of Life Technology by SCHULZ, Richard, BEACH, Scott R, TABOLT MATTHEWS, Judith, COURTNEY, Karen L, DE VITO DABBS, Annette J

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Comparison of the toxicity of naphthalene and naphthalene-1,2-dihydrodiol (DIOL) by Billings, R E, Miller, N E, Dabbs, J E, LeValley, S E, Hill, J R, Green, C E

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In vivo and in vitro evidence for in situ activation and selective covalent binding of acetaminophen (APAP) in mouse kidney by Emeigh Hart, S G, Birge, R B, Cartun, R W, Tyson, C A, Dabbs, J E, Nishanian, E V, Wyand, D S, Khairallah, E A, Cohen, S D

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Stress initiated during isolation of rat renal proximal tubules limits in vitro survival by Green, C E, Dabbs, J E, Tyson, C A, Rauckman, E J

“…The effects of oxidative damage were assessed in rat proximal tubule fragments (isolated by collagenase perfusion) by monitoring lactate dehydrogenase release…”
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