Search Results - "DA FONSECA, Anna"

A Narrative Review of the Antitumor Activity of Monoterpenes from Essential Oils: An Update by Machado, Thaíssa Q., da Fonseca, Anna C. C., Duarte, Allana B. S., Robbs, Bruno K., de Sousa, Damião P.

“…Monoterpenes are a group of natural products that have been widely studied due to their therapeutic potential against various pathologies. These compounds are…”
Get full text

Role of lysophosphatidic acid and its receptors in health and disease: novel therapeutic strategies by Geraldo, Luiz Henrique Medeiros, Spohr, Tânia Cristina Leite de Sampaio, Amaral, Rackele Ferreira do, Fonseca, Anna Carolina Carvalho da, Garcia, Celina, Mendes, Fabio de Almeida, Freitas, Catarina, dosSantos, Marcos Fabio, Lima, Flavia Regina Souza

“…Lysophosphatidic acid (LPA) is an abundant bioactive phospholipid, with multiple functions both in development and in pathological conditions. Here, we review…”
Get full text

Molecular Modeling and In Vitro Evaluation of Piplartine Analogs against Oral Squamous Cell Carcinoma by Silva, Rayanne H N, Machado, Thaíssa Q, da Fonseca, Anna Carolina C, Tejera, Eduardo, Perez-Castillo, Yunierkis, Robbs, Bruno K, de Sousa, Damião P

“…Cancer is a principal cause of death in the world, and providing a better quality of life and reducing mortality through effective pharmacological treatment…”
Get full text

Microglia and Macrophages in Malignant Gliomas: Recent Discoveries and Implications for Promising Therapies by Carvalho da Fonseca, Anna Carolina, Badie, Behnam

“…Malignant gliomas are the most common primary brain tumors. Their deadliest manifestation, glioblastoma multiforme (GBM), accounts for 15% of all primary brain…”
Get full text

In-vitro evaluation studies of 7-chloro-4-aminoquinoline Schiff bases and their copper complexes as cholinesterase inhibitors by Zanon, Vanessa S., Lima, Josélia A., Cuya, Teobaldo, Lima, Flavia R.S., da Fonseca, Anna C.C., Gomez, Javier G., Ribeiro, Ronny R., França, Tanos C.C., Vargas, Maria D.

“…Alzheimer's disease (AD) is one of the most common age-related neurodegenerative disorders. Aggregation of amyloid-β peptide into extracellular plaques with…”
Get full text

The impact of microglial activation on blood-brain barrier in brain diseases by da Fonseca, Anna Carolina Carvalho, Matias, Diana, Garcia, Celina, Amaral, Rackele, Geraldo, Luiz Henrique, Freitas, Catarina, Lima, Flavia Regina Souza

“…The blood-brain barrier (BBB), constituted by an extensive network of endothelial cells (ECs) together with neurons and glial cells, including microglia, forms…”
Get full text

RAGE expression in tumor-associated macrophages promotes angiogenesis in glioma by Chen, Xuebo, Zhang, Leying, Zhang, Ian Y, Liang, Junling, Wang, Huaqing, Ouyang, Mao, Wu, Shihua, da Fonseca, Anna Carolina Carvalho, Weng, Lihong, Yamamoto, Yasuhiko, Yamamoto, Hiroshi, Natarajan, Rama, Badie, Behnam

“…Interaction of RAGE (the receptor for advanced glycation endproducts) with its ligands can promote tumor progression, invasion, and angiogenesis. Although…”
Get full text

Geissoschizoline, a promising alkaloid for Alzheimer’s disease: Inhibition of human cholinesterases, anti-inflammatory effects and molecular docking by Lima, Josélia A., R. Costa, Thiago Wilson, da Fonseca, Anna C.C., do Amaral, Rackele F., Nascimento, Maria do Desterro S.B., Santos-Filho, Osvaldo A., de Miranda, Ana Luísa P., Ferreira Neto, Denise Cristian, Lima, Flavia R.S., Hamerski, Lidilhone, Tinoco, Luzineide W.

“…[Display omitted] •Geissoschizoline is a potent inhibitor of both humans AChE and BChE.•Geissoschizoline plays a promising anti-inflammatory role.•It reduces…”
Get full text

Extracellular alpha-synuclein: Sensors, receptors, and responses by Domingues, Renato, Sant’Anna, Ricardo, da Fonseca, Anna Carolina Carvalho, Robbs, Bruno K., Foguel, Debora, Outeiro, Tiago F.

“…Synucleinopathies are a group of progressive neurodegenerative diseases known for the accumulation of insoluble aggregates containing the protein…”
Get full text

The orthotopic xenotransplant of human glioblastoma successfully recapitulates glioblastoma-microenvironment interactions in a non-immunosuppressed mouse model by Garcia, Celina, Dubois, Luiz Gustavo, Xavier, Anna Lenice, Geraldo, Luiz Henrique, da Fonseca, Anna Carolina Carvalho, Correia, Ana Helena, Meirelles, Fernanda, Ventura, Grasiella, Romão, Luciana, Canedo, Nathalie Henriques Silva, de Souza, Jorge Marcondes, de Menezes, João Ricardo Lacerda, Moura-Neto, Vivaldo, Tovar-Moll, Fernanda, Lima, Flavia Regina Souza

“…Glioblastoma (GBM) is the most common primary brain tumor and the most aggressive glial tumor. This tumor is highly heterogeneous, angiogenic, and insensitive…”
Get full text

Pro-Apoptotic Antitumoral Effect of Novel Acridine-Core Naphthoquinone Compounds against Oral Squamous Cell Carcinoma by Zorzanelli, Bruna Costa, Ouverney, Gabriel, Pauli, Fernanda P, da Fonseca, Anna Carolina Carvalho, de Almeida, Elan Cardozo Paes, de Carvalho, Danielle Gonçalves, Possik, Patricia Abrão, Rabelo, Vitor Won-Held, Abreu, Paula Alvarez, Pontes, Bruno, Ferreira, Vitor Francisco, Forezi, Luana da Silva Magalhães, da Silva, Fernando de Carvalho, Robbs, Bruno Kaufmann

“…Oral squamous cell carcinoma (OSCC) is a global public health problem with high incidence and mortality. The chemotherapeutic agents used in the clinic, alone…”
Get full text

Liquid biopsy evaluation of circulating tumor DNA, miRNAs, and cytokines in meningioma patients by Aran, Veronica, Lyra Miranda, Renan, Heringer, Manoela, Carvalho da Fonseca, Anna Carolina, Andreiuolo, Felipe, Chimelli, Leila, Devalle, Sylvie, Niemeyer Filho, Paulo, Moura-Neto, Vivaldo

“…Liquid biopsy is a non-invasive method used to detect cancer and monitor treatment responses by analyzing blood or other bodily fluids for cancer biomarkers…”
Get full text

Chemoselective Synthesis of Mannich Adducts from 1,4-Naphthoquinones and Profile as Autophagic Inducers in Oral Squamous Cell Carcinoma by Borges, Amanda A, de Souza, Michele P, da Fonseca, Anna Carolina C, Wermelinger, Guilherme F, Ribeiro, Ruan C B, Amaral, Adriane A P, de Carvalho, Cláudio José C, Abreu, Lucas S, de Queiroz, Lucas Nicolau, de Almeida, Elan C P, Rabelo, Vitor W, Abreu, Paula A, Pontes, Bruno, Ferreira, Vitor F, da Silva, Fernando de C, Forezi, Luana da S M, Robbs, Bruno K

“…Oral squamous cell carcinoma (OSCC) is a worldwide public health problem, accounting for approximately 90% of all oral cancers, and is the eighth most common…”
Get full text

On the fate of extracellular hemoglobin and heme in brain by Lara, Flavio A, Kahn, Suzana A, Fonseca, Anna CC da, Bahia, Carlomagno P, Pinho, João PC, Graca-Souza, Aurélio V, Houzel, Jean C, de Oliveira, Pedro L, Moura-Neto, Vivaldo, Oliveira, Marcus F

“…Intracerebral hemorrhage (ICH) is a major cause of disability in adults worldwide. The pathophysiology of this syndrome is complex, involving both inflammatory…”
Get full text

Pathophysiology and mechanisms of hearing impairment related to neonatal infection diseases by Capra, Daniela, DosSantos, Marcos F, Sanz, Carolina K, Acosta Filha, Lionete Gall, Nunes, Priscila, Heringer, Manoela, Ximenes-da-Silva, Adriana, Pessoa, Luciana, de Mattos Coelho-Aguiar, Juliana, da Fonseca, Anna Carolina Carvalho, Mendes, Carmelita Bastos, da Rocha, Lanni Sarmento, Devalle, Sylvie, Niemeyer Soares Filho, Paulo, Moura-Neto, Vivaldo

“…The inner ear, the organ of equilibrium and hearing, has an extraordinarily complex and intricate arrangement. It contains highly specialized structures…”
Get full text

Increased expression of stress inducible protein 1 in glioma-associated microglia/macrophages by Carvalho da Fonseca, Anna Carolina, Wang, Huaqing, Fan, Haitao, Chen, Xuebo, Zhang, Ian, Zhang, Leying, Lima, Flavia Regina Souza, Badie, Behnam

“…Abstract Factors released by glioma-associated microglia/macrophages (GAMs) play an important role in the growth and infiltration of tumors. We have previously…”
Get full text

Apoptotic effect of β-pinene on oral squamous cell carcinoma as one of the major compounds from essential oil of medicinal plant Piper rivinoides Kunth by Machado, Thaíssa Queiróz, Felisberto, Jessica Regina Sales, Guimarães, Elsie Franklin, Queiroz, George Azevedo de, Fonseca, Anna Carolina Carvalho da, Ramos, Ygor Jessé, Marques, André Mesquita, Moreira, Davyson de Lima, Robbs, Bruno Kaufmann

“…Oral squamous cell carcinoma (OSCC) is the most common type of head and neck malignancy. Research on essential oils (EOs) has shown important cytotoxic and…”
Get full text

Fouling mitigation in produced water treatment by conjugation of advanced oxidation process and microfiltration by Ferreira, Anna Danielli da Fonseca, Coelho, Déborah Regina Bispo, dos Santos, Rafael Victor Gomes, Nascimento, Kleby Soares, Presciliano, Fabricio de Andrade, da Silva, Felipe Pereira, Campos, Juacyara Carbonelli, da Fonseca, Fabiana Valéria, Borges, Cristiano Piacsek, Weschenfelder, Silvio Edegar

“…This work explored the use of ozonation and photoperoxidation before the microfiltration process to reduce fouling. Produced water was synthesized with salt,…”
Get full text

Glioblastoma: Therapeutic challenges, what lies ahead by Lima, Flavia R.S., Kahn, Suzana Assad, Soletti, Rossana C., Biasoli, Deborah, Alves, Tercia, da Fonseca, Anna Carolina C., Garcia, Celina, Romão, Luciana, Brito, José, Holanda-Afonso, Rosenilde, Faria, Jane, Borges, Helena, Moura-Neto, Vivaldo

“…Glioblastoma (GBM) is one of the most aggressive human cancers. Despite current advances in multimodality therapies, such as surgery, radiotherapy and…”
Get full text

The multiple functions of the co-chaperone stress inducible protein 1 by da Fonseca, Anna Carolina Carvalho, Matias, Diana, Geraldo, Luiz Henrique Medeiros, Leser, Felipe Saceanu, Pagnoncelli, Iohana, Garcia, Celina, do Amaral, Rackele Ferreira, da Rosa, Barbara Gomes, Grimaldi, Izabella, de Camargo Magalhães, Eduardo Sabino, Cóppola-Segovia, Valentín, de Azevedo, Evellyn Mayla, Zanata, Silvio Marques, Lima, Flavia Regina Souza

“…[Display omitted] •STI1 is a co-chaperone involved in the correct client proteins' folding.•Extracellular STI1 is crucial for CNS maintenance and…”
Get full text