Search Results - "DA CUNHA, ISABELA WERNECK"
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Prognostic value of PD-L1 expression for surgically treated localized renal cell carcinoma: implications for risk stratification and adjuvant therapies
Published in Therapeutic advances in urology (2019)“…Background: We aimed to evaluate the prognostic role of programmed-death receptor ligand (PD-L1) in a multinational cohort of patients with localized renal…”
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GLUT1 and GLUT3 as potential prognostic markers for Oral Squamous Cell Carcinoma
Published in Molecules (Basel, Switzerland) (01-04-2010)“…We associated clinical-pathological features of 142 OSCC with the expression pattern of GLUT1 and GLUT3 in order to estimate their prognostic value…”
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Let-7 miRNA's Expression Profile and Its Potential Prognostic Role in Uterine Leiomyosarcoma
Published in Cells (Basel, Switzerland) (17-11-2019)“…The family is an important microRNA (miRNA) group that usually exerts functions as a tumor suppressor. We aimed to evaluate the expression profile of , and and…”
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Could miRNA Signatures be Useful for Predicting Uterine Sarcoma and Carcinosarcoma Prognosis and Treatment?
Published in Cancers (06-09-2018)“…Changes in microRNA (miRNA) expression may lead to cancer development and/or contribute to its progression; however, their role in uterine sarcomas is poorly…”
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Mutational Portrait of Lung Adenocarcinoma in Brazilian Patients: Past, Present, and Future of Molecular Profiling in the Clinic
Published in Frontiers in oncology (02-07-2020)“…Objectives: Approximately 60% of lung adenocarcinomas (LAs) carry mutations that can guide treatment with tyrosine-kinase inhibitors (TKI) and other targeted…”
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The Role of Immunohistochemical Analysis as a Tool for the Diagnosis, Prognostic Evaluation and Treatment of Prostate Cancer: A Systematic Review of the Literature
Published in Frontiers in oncology (18-09-2018)“…Prostate cancer (PCa) is a heterogeneous disease that lends itself toward numerous therapeutic options depending on its risk stratification. One of the…”
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Pericytic tumors of the kidney—a clinicopathologic analysis of 17 cases
Published in Human pathology (01-06-2017)“…Summary The pericytic (perivascular myoid cell) family of tumors is a distinctive group of mesenchymal neoplasms encountered in superficial sites and only…”
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External validation of nomogram to predict inguinal lymph node metastasis in patients with penile cancer and clinically negative lymph nodes
Published in International Brazilian Journal of Urology (01-07-2019)“…ABSTRACT Introduction Penile cancer (PC) occurs less frequently in Europe and in the United States than in South America and parts of Africa. Lymph node (LN)…”
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A genomic case study of desmoplastic small round cell tumor: comprehensive analysis reveals insights into potential therapeutic targets and development of a monitoring tool for a rare and aggressive disease
Published in Human genomics (18-11-2016)“…Genome-wide profiling of rare tumors is crucial for improvement of diagnosis, treatment, and, consequently, achieving better outcomes. Desmoplastic small round…”
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10
Epidermal growth factor receptor as an adverse survival predictor in squamous cell carcinoma of the penis
Published in Human pathology (01-03-2017)“…Penile carcinoma (PC) is more frequent in underdeveloped countries, generally is diagnosed at an advanced stage when therapeutic options are restricted, and…”
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High-Resolution Magic-Angle-Spinning NMR in Revealing Hepatoblastoma Hallmarks
Published in Biomedicines (01-12-2022)“…Cancer is one of the leading causes of death in children and adolescents worldwide; among the types of liver cancer, hepatoblastoma (HBL) is the most common in…”
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Loss of 5'-Methylthioadenosine Phosphorylase (MTAP) is Frequent in High-Grade Gliomas; Nevertheless, it is Not Associated with Higher Tumor Aggressiveness
Published in Cells (Basel, Switzerland) (20-02-2020)“…The 5'-methylthioadenosine phosphorylase (MTAP) gene is located in the chromosomal region 9p21. deletion is a frequent event in a wide variety of human…”
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Brazilian Expert Consensus for NTRK Gene Fusion Testing in Solid Tumors
Published in Clinical Pathology (01-01-2023)“…Oncogenic neurotrophic tropomyosin receptor kinase gene fusions occur in less than 1% of common cancers. These mutations have emerged as new biomarkers in…”
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Urological cancer related to familial syndromes
Published in International Brazilian Journal of Urology (01-03-2017)“…Cancer related to hereditary syndromes corresponds to approximately 5-10% of all tumors. Among those from the genitourinary system, many tumors had been…”
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Radical prostatectomy and positive surgical margins: relationship with prostate cancer outcome
Published in International Brazilian Journal of Urology (01-06-2014)“…Positive surgical margins (PSMs) are an adverse factor that may predict a worse outcome in patients submitted to radical prostatectomy (RP). However, not all…”
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Immunohistochemical expression of CD44s in renal cell carcinoma lacks independent prognostic significance
Published in International Brazilian journal of urology (01-08-2012)“…To analyze the immunohistochemical expression of the standard isoform of CD44 (CD44s) adhesion molecule in clear cell renal cell carcinoma (CCRCC) and its…”
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Tubulocystic Carcinoma of the Kidney With Poorly Differentiated Foci: A Frequent Morphologic Pattern of Fumarate Hydratase-deficient Renal Cell Carcinoma
Published in The American journal of surgical pathology (01-11-2016)“…An emerging group of high-grade renal cell carcinomas (RCCs), particularly carcinomas arising in the hereditary leiomyomatosis renal cell carcinoma syndrome…”
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Loss of RKIP expression during the carcinogenic evolution of endometrial cancer
Published in Journal of clinical pathology (01-02-2012)“…Endometrial cancer is one of the most common cancers in women worldwide, but there is a lack of diagnostic markers for early detection of these tumours. The…”
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Bannayan-Riley-Ruvalcaba syndrome with deforming lipomatous hamartomas in infant--case report
Published in Anais brasileiros de dermatología (01-12-2013)“…Bannayan-Riley-Ruvalcaba Syndrome is a rare condition caused by mutations in the PTEN gene. It displays association of multiple lipomas, macrocephaly,…”
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Neuromuscular Choristoma: Report of Five Cases With CTNNB1 Sequencing
Published in Journal of neuropathology and experimental neurology (01-11-2021)“…Abstract Neuromuscular choristoma (NMC) are lesions of the peripheral nervous system characterized by an admixture of skeletal muscle fibers and nerves…”
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