Search Results - "D. Schmitt"

Cutoff Finder: a comprehensive and straightforward Web application enabling rapid biomarker cutoff optimization by Budczies, Jan, Klauschen, Frederick, Sinn, Bruno V, Győrffy, Balázs, Schmitt, Wolfgang D, Darb-Esfahani, Silvia, Denkert, Carsten

“…Gene or protein expression data are usually represented by metric or at least ordinal variables. In order to translate a continuous variable into a clinical…”
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A Compendium of Chromatin Contact Maps Reveals Spatially Active Regions in the Human Genome by Schmitt, Anthony D., Hu, Ming, Jung, Inkyung, Xu, Zheng, Qiu, Yunjiang, Tan, Catherine L., Li, Yun, Lin, Shin, Lin, Yiing, Barr, Cathy L., Ren, Bing

“…The three-dimensional configuration of DNA is integral to all nuclear processes in eukaryotes, yet our knowledge of the chromosome architecture is still…”
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Mapping of long-range chromatin interactions by proximity ligation-assisted ChIP-seq by Fang, Rongxin, Yu, Miao, Li, Guoqiang, Chee, Sora, Liu, Tristin, Schmitt, Anthony D, Ren, Bing

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A high-resolution map of the three-dimensional chromatin interactome in human cells by Jin, Fulai, Li, Yan, Dixon, Jesse R., Selvaraj, Siddarth, Ye, Zhen, Lee, Ah Young, Yen, Chia-An, Schmitt, Anthony D., Espinoza, Celso A., Ren, Bing

“…A novel approach to analyse high-depth Hi-C data provides a comprehensive chromatin interaction map at approximately 5–10 kb resolution in human fibroblasts;…”
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Targeted inhibition of glycogen synthase kinase-3 using 9-ING-41 (elraglusib) enhances CD8 T-cell-reactivity against neuroblastoma cells by Markovska, A., Somers, K., Guillaume, J., Melief, J., Mazar, A. P., Schmitt, D. M., Schipper, H. S., Boes, M.

“…The prognosis of patients with high-risk neuroblastoma remains poor, partly due to inadequate immune recognition of the tumor. Neuroblastomas display extremely…”
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Forelimb and hind limb loading patterns during below branch quadrupedal locomotion in the two‐toed sloth by Granatosky, M. C., Schmitt, D.

“…The living sloths are the most suspensory of all extant mammals, and therefore represent ideal models for investigating the effects that suspensory behaviours…”
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Surface Flux Transport Modeling for Solar Cycles 15-21: Effects of Cycle-Dependent Tilt Angles of Sunspot Groups by Cameron, R. H, Jiang, J, Schmitt, D, Schüssler, M

“…We model the surface magnetic field and open flux of the Sun from 1913 to 1986 using a surface flux transport model, which includes the observed cycle-to-cycle…”
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Frictional Stabilities on Induced Earthquake Fault Planes at Fox Creek, Alberta: A Pore Fluid Pressure Dilemma by Shen, L. W., Schmitt, D. R., Schultz, R.

“…Earthquakes induced during hydraulic fracturing operations have occurred in a number of locales. However, in situ studies aimed to discern the triggering…”
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Epidermal growth factor receptor inhibition attenuates liver fibrosis and development of hepatocellular carcinoma by Fuchs, Bryan C., Hoshida, Yujin, Fujii, Tsutomu, Wei, Lan, Yamada, Suguru, Lauwers, Gregory Y., McGinn, Christopher M., DePeralta, Danielle K., Chen, Xintong, Kuroda, Toshihiko, Lanuti, Michael, Schmitt, Anthony D., Gupta, Supriya, Crenshaw, Andrew, Onofrio, Robert, Taylor, Bradley, Winckler, Wendy, Bardeesy, Nabeel, Caravan, Peter, Golub, Todd R., Tanabe, Kenneth K.

“…Hepatocellular carcinoma (HCC) is the most rapidly increasing cause of cancer‐related mortality in the United States. Because of the lack of viable treatment…”
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Common DNA sequence variation influences 3-dimensional conformation of the human genome by Gorkin, David U, Qiu, Yunjiang, Hu, Ming, Fletez-Brant, Kipper, Liu, Tristin, Schmitt, Anthony D, Noor, Amina, Chiou, Joshua, Gaulton, Kyle J, Sebat, Jonathan, Li, Yun, Hansen, Kasper D, Ren, Bing

“…The 3-dimensional (3D) conformation of chromatin inside the nucleus is integral to a variety of nuclear processes including transcriptional regulation, DNA…”
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Efficient orbital imaging based on ultrafast momentum microscopy and sparsity-driven phase retrieval by Jansen, G S M, Keunecke, M, Düvel, M, Möller, C, Schmitt, D, Bennecke, W, Kappert, F J S, Steil, D, Luke, D R, Steil, S, Mathias, S

“…We present energy-resolved photoelectron momentum maps for orbital tomography that have been collected with a novel and efficient time-of-flight momentum…”
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Accumulated Metabolites of Hydroxybutyric Acid Serve as Diagnostic and Prognostic Biomarkers of Ovarian High-Grade Serous Carcinomas by Hilvo, Mika, de Santiago, Ines, Gopalacharyulu, Peddinti, Schmitt, Wolfgang D, Budczies, Jan, Kuhberg, Marc, Dietel, Manfred, Aittokallio, Tero, Markowetz, Florian, Denkert, Carsten, Sehouli, Jalid, Frezza, Christian, Darb-Esfahani, Silvia, Braicu, Elena Ioana

“…Ovarian cancer is a heterogeneous disease of low prevalence, but poor survival. Early diagnosis is critical for survival, but it is often challenging because…”
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A NEW SIMPLE DYNAMO MODEL FOR STELLAR ACTIVITY CYCLE by Yokoi, N., Schmitt, D., Pipin, V., Hamba, F.

“…ABSTRACT A new simple dynamo model for stellar activity cycle is proposed. By considering an inhomogeneous flow effect on turbulence, it is shown that…”
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Risk of capture is modified by hypoxia and interjurisdictional migration of Lake Whitefish (Coregonusclupeaformis) by Kraus, Richard T., Cook, H. Andrew, Sakas, Alexis, MacDougall, Thomas M., Faust, Matthew D., Schmitt, Joseph D., Vandergoot, Christopher S.

“…Interjurisdictional migrations lead to seasonally changing patterns of exploitation risk, emphasizing the importance of spatially explicit approaches to…”
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Toxicological Evaluation of β-Caryophyllene Oil: Subchronic Toxicity in Rats by Schmitt, D., Levy, R., Carroll, B.

“…In a subchronic toxicity study, administration of β-caryophyllene (BCP) oil by oral gavage to Wistar rats at dosages of 0, 150, 450, or 700 mg/kg/d for 90…”
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Mutational Diversity and Therapy Response in Breast Cancer: A Sequencing Analysis in the Neoadjuvant GeparSepto Trial by Loibl, Sibylle, Treue, Denise, Budczies, Jan, Weber, Karsten, Stenzinger, Albrecht, Schmitt, Wolfgang D, Weichert, Wilko, Jank, Paul, Furlanetto, Jenny, Klauschen, Frederick, Karn, Thomas, Pfarr, Nicole, von Minckwitz, Gunter, Möbs, Markus, Jackisch, Christian, Sers, Christine, Schneeweiss, Andreas, Fasching, Peter A, Schem, Christian, Hummel, Michael, van Mackelenbergh, Marion, Nekljudova, Valentina, Untch, Michael, Denkert, Carsten

“…Next-generation sequencing (NGS) can be used for comprehensive investigation of molecular events in breast cancer. We evaluated the relevance of genomic…”
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Independent evolutionary origin of fem paralogous genes and complementary sex determination in hymenopteran insects by Koch, Vasco, Nissen, Inga, Schmitt, Björn D, Beye, Martin

“…The primary signal of sex determination in the honeybee, the complementary sex determiner (csd) gene, evolved from a gene duplication event from an ancestral…”
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Characterization of Hormone Receptor and HER2 Status in Breast Cancer Using Mass Spectrometry Imaging by Gonçalves, Juliana Pereira Lopes, Bollwein, Christine, Noske, Aurelia, Jacob, Anne, Jank, Paul, Loibl, Sibylle, Nekljudova, Valentina, Fasching, Peter A, Karn, Thomas, Marmé, Frederik, Müller, Volkmar, Schem, Christian, Sinn, Bruno Valentin, Stickeler, Elmar, van Mackelenbergh, Marion, Schmitt, Wolfgang D, Denkert, Carsten, Weichert, Wilko, Schwamborn, Kristina

“…Immunohistochemical evaluation of estrogen receptor, progesterone receptor, and human epidermal growth factor receptor-2 status stratify the different subtypes…”
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Coagulation/Flocculation with Moringa oleifera and Membrane Filtration for Dairy Wastewater Treatment by Mateus, G. A. P., Formentini-Schmitt, D. M., Nishi, L., Fagundes-Klen, M. R., Gomes, R. G., Bergamasco, R.

“…The main objective of the present paper is to evaluate the use of Moringa oleifera (MO) as a natural coagulant in coagulation/flocculation/sedimentation (CFS)…”
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Factors contributing to racial differences in gait mechanics differ by sex by Hill, C.N., Reed, W., Schmitt, D., Arent, S.M., Sands, L.P., Queen, R.M.

“…•Racial differences in female gait were explained by Q-angle and ankle strength.•Racial differences in gait were unexplained in males.•Factors contributing to…”
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