Search Results - "D. R. Welch"

Breast cancer metastasis suppressor-1 promoter methylation in cell-free DNA provides prognostic information in non-small cell lung cancer by Balgkouranidou, I, Chimonidou, M, Milaki, G, Tsarouxa, E G, Kakolyris, S, Welch, D R, Georgoulias, V, Lianidou, E S

“…Background: Breast-cancer metastasis suppressor 1 ( BRMS1 ) gene encodes for a predominantly nuclear protein that differentially regulates the expression of…”
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Prognostic significance of BRMS1 expression in human melanoma and its role in tumor angiogenesis by Li, J, Cheng, Y, Tai, D, Martinka, M, Welch, D R, Li, G

“…Breast cancer metastasis suppressor 1 (BRMS1) has been reported to suppress metastasis without significantly affecting tumorigenicity in breast cancer and…”
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Magnetized particle transport in multi-MA accelerators by Bennett, N., Welch, D. R., Laity, G., Rose, D. V., Cuneo, M. E.

“…Kinetic simulations of Sandia National Laboratories’Z machine are conducted to understand particle transport in the highly magnetized environment of a multi-MA…”
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Fast hybrid particle-in-cell technique for pulsed-power accelerators by Welch, D. R., Bennett, N., Genoni, T. C., Thoma, C., Rose, D. V.

“…Hybrid-implicit particle-in-cell (PIC) algorithms permit the simulation of complex problems involving both kinetic and fluid plasma regimes over large spatial…”
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Electrode plasma formation and melt in Z -pinch accelerators by Bennett, N., Welch, D. R., Cochrane, K., Leung, K., Thoma, C., Cuneo, M. E., Frye-Mason, G.

“…Recent studies of power flow and particle transport in multi-MA pulsed-power accelerators demonstrate that electrode plasmas may reduce accelerator efficiency…”
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Computational analysis of current-loss mechanisms in a post-hole convolute driven by magnetically insulated transmission lines by Rose, D. V., Madrid, E. A., Welch, D. R., Clark, R. E., Mostrom, C. B., Stygar, W. A., Cuneo, M. E.

“…Numerical simulations of a vacuum post-hole convolute driven by magnetically insulated vacuum transmission lines (MITLs) are used to study current losses due…”
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Three-dimensional time-domain particle-in-cell calculations of impedances and centroid deflections in a linear-accelerator cell by Thoma, C., Welch, D. R., Russell, A. M., Clark, R. E., Rose, D. V., Stygar, W. A., Kelsall, B. J.

“…In linear induction accelerators, high-brightness electron beams are accelerated by voltages applied at gaps at discrete locations along the accelerator. At…”
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Dynamics of the super pinch electron beam and fusion energy perspective by Welch, D. R., Rose, D. V., Novikov, D. V., Weller, M. E., Esaulov, A. A., Miley, G. H.

“…The characterization of a high current, relativistic electron beam, designated the Super Pinch electron beam, has been performed using compact pulsed-power…”
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Current transport and loss mechanisms in the Z accelerator by Bennett, N., Welch, D. R., Jennings, C. A., Yu, E., Hess, M. H., Hutsel, B. T., Laity, G., Moore, J. K., Rose, D. V., Peterson, K., Cuneo, M. E.

“…A challenge for the TW-class accelerators drivingZ-pinch experiments, such as Sandia National Laboratories’Zmachine, is to efficiently couple power from…”
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Drift compression of an intense neutralized ion beam by ROY, P. K, YU, S. S, WALDRON, W. L, WELCH, D. R, THOMA, C, SEFKOW, A. B, GILSON, E. P, EFTHIMION, P. C, DAVIDSON, R. C, HENESTROZA, E, ANDERS, A, BIENIOSEK, F. M, COLEMAN, J, EYLON, S, GREENWAY, W. G, LEITNER, M, LOGAN, B. G

“…Longitudinal compression of a velocity-tailored, intense neutralized beam at 300 keV, 25 mA has been demonstrated. The compression takes place in a 1-2 m drift…”
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Transmission-line-circuit model of an 85-TW, 25-MA pulsed-power accelerator by Hutsel, B. T., Corcoran, P. A., Cuneo, M. E., Gomez, M. R., Hess, M. H., Hinshelwood, D. D., Jennings, C. A., Laity, G. R., Lamppa, D. C., McBride, R. D., Moore, J. K., Myers, A., Rose, D. V., Slutz, S. A., Stygar, W. A., Waisman, E. M., Welch, D. R., Whitney, B. A.

“…We have developed a physics-based transmission-line-circuit model of the Z pulsed-power accelerator. The 33-m-diameter Z machine generates a peak electrical…”
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Numerical simulations of enhanced ion current losses in the inner magnetically insulated transmission line of the Z accelerator by Rose, D. V., Waisman, E. M., Desjarlais, M. P., Cuneo, M. E., Hutsel, B. T., Welch, D. R., Bennett, N., Laity, G. R.

“…Two-dimensional electromagnetic (EM) particle-in-cell (PIC) simulations of a radial magnetically-insulated-transmission-line are presented and compared to the…”
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Simulation of heating-compressed fast-ignition cores by petawatt laser-generated electrons by CAMPBELL, R. B, KODAMA, R, MEHLHORN, T. A, TANAKA, K. A, WELCH, D. R

“…We report on unique particle-in-cell simulations to understand the relativistic electron beam thermalization and subsequent heating of highly compressed…”
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Adaptive particle management in a particle-in-cell code by Welch, D.R., Genoni, T.C., Clark, R.E., Rose, D.V.

“…In particle-based plasma simulation, when dealing with source terms such as ionization, emission from boundaries, etc., the total number of particles can grow,…”
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Steady-state modeling of current loss in a post-hole convolute driven by high power magnetically insulated transmission lines by Madrid, E. A., Rose, D. V., Welch, D. R., Clark, R. E., Mostrom, C. B., Stygar, W. A., Cuneo, M. E., Gomez, M. R., Hughes, T. P., Pointon, T. D., Seidel, D. B.

“…Quasiequilibrium power flow in two radial magnetically insulated transmission lines (MITLs) coupled to a vacuum post-hole convolute is studied at 50  TW–200 …”
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Three-dimensional electromagnetic model of the pulsed-power Z -pinch accelerator by Rose, D. V., Welch, D. R., Madrid, E. A., Miller, C. L., Clark, R. E., Stygar, W. A., Savage, M. E., Rochau, G. A., Bailey, J. E., Nash, T. J., Sceiford, M. E., Struve, K. W., Corcoran, P. A., Whitney, B. A.

“…A three-dimensional, fully electromagnetic model of the principal pulsed-power components of the 26-MA ZR accelerator [D. H. McDaniel et al., in Proceedings of…”
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Functional evidence for a novel human breast carcinoma metastasis suppressor, BRMS1, encoded at chromosome 11q13 by JABED SERAJ, M, SAMANT, R. S, VERDERAME, M. F, WELCH, D. R

“…We previously showed that introduction of a normal, neomycin-tagged human chromosome 11 reduces the metastatic capacity of MDA-MB-435 (435) human breast…”
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C16 laminin peptide increases angiotropic extravascular migration of human melanoma cells in a shell-less chick chorioallantoic membrane assay by Lugassy, C., Kleinman, H.K., Vernon, S.E., Welch, D.R., Barnhill, R.L.

“…Summary Background  As distinct from intravascular dissemination, extravascular migratory metastasis (EVMM) has been described as a potential additional…”
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Suppression of metastasis in human breast carcinoma MDA-MB-435 cells after transfection with the metastasis suppressor gene, KiSS-1 by LEE, J.-H, WELCH, D. R

“…Based on the observation that chromosome 1q deletions are not infrequent in late-stage human breast carcinomas, we tested whether the recently discovered human…”
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KiSS-1, a Novel Human Malignant Melanoma Metastasis-Suppressor Gene by Lee, Jeong-Hyung, Miele, Mary E., Hicks, Deana J., Phillips, Karen K., Trent, Jeffery M., Weissman, Bernard E., Welch, Danny R.

“…Background Microcell-mediated transfer of chromosome 6 into human C8161 and MelJuSo melanoma cells suppresses their ability to metastasize by at least 95%…”
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