Search Results - "D. Pozzi"

Brain mapping across 16 autism mouse models reveals a spectrum of functional connectivity subtypes by Zerbi, V., Pagani, M., Markicevic, M., Matteoli, M., Pozzi, D., Fagiolini, M., Bozzi, Y., Galbusera, A., Scattoni, M. L., Provenzano, G., Banerjee, A., Helmchen, F., Basson, M. A., Ellegood, J., Lerch, J. P., Rudin, M., Gozzi, A., Wenderoth, N.

“…Autism Spectrum Disorder (ASD) is characterized by substantial, yet highly heterogeneous abnormalities in functional brain connectivity. However, the origin…”
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An apolipoprotein-enriched biomolecular corona switches the cellular uptake mechanism and trafficking pathway of lipid nanoparticles by Digiacomo, L, Cardarelli, F, Pozzi, D, Palchetti, S, Digman, M A, Gratton, E, Capriotti, A L, Mahmoudi, M, Caracciolo, G

“…Following exposure to biological milieus (e.g. after systemic administration), nanoparticles (NPs) get covered by an outer biomolecular corona (BC) that…”
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The biomolecular corona of nanoparticles in circulating biological media by Pozzi, D, Caracciolo, G, Digiacomo, L, Colapicchioni, V, Palchetti, S, Capriotti, A L, Cavaliere, C, Zenezini Chiozzi, R, Puglisi, A, Laganà, A

“…When nanoparticles come into contact with biological media, they are covered by a biomolecular 'corona', which confers a new identity to the particles. In all…”
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Nanoparticles-cell association predicted by protein corona fingerprints by Palchetti, S, Digiacomo, L, Pozzi, D, Peruzzi, G, Micarelli, E, Mahmoudi, M, Caracciolo, G

“…In a physiological environment (e.g., blood and interstitial fluids) nanoparticles (NPs) will bind proteins shaping a "protein corona" layer. The long-lived…”
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Clinically approved PEGylated nanoparticles are covered by a protein corona that boosts the uptake by cancer cells by Papi, M, Caputo, D, Palmieri, V, Coppola, R, Palchetti, S, Bugli, F, Martini, C, Digiacomo, L, Pozzi, D, Caracciolo, G

“…Today, liposomes are an advanced technology of drug carriers with a dozen drugs in clinical practice and many more in clinical trials. A bottleneck associated…”
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Mechanistic evaluation of the transfection barriers involved in lipid-mediated gene delivery: Interplay between nanostructure and composition by Pozzi, D., Marchini, C., Cardarelli, F., Salomone, F., Coppola, S., Montani, M., Zabaleta, M. Elexpuru, Digman, M.A., Gratton, E., Colapicchioni, V., Caracciolo, G.

“…Here we present a quantitative mechanism-based investigation aimed at comparing the cell uptake, intracellular trafficking, endosomal escape and final fate of…”
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In vivo protein corona patterns of lipid nanoparticles by Amici, A., Caracciolo, G., Digiacomo, L., Gambini, V., Marchini, C., Tilio, M., Capriotti, A. L., Colapicchioni, V., Matassa, R., Familiari, G., Palchetti, S., Pozzi, D., Mahmoudi, M., Laganà, A.

“…In physiological environments ( e.g. the blood), nanoparticles (NPs) are surrounded by a layer of biomolecules referred to as a ‘protein corona’ (PC). The most…”
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Reduced SNAP-25 increases PSD-95 mobility and impairs spine morphogenesis by Fossati, G, Morini, R, Corradini, I, Antonucci, F, Trepte, P, Edry, E, Sharma, V, Papale, A, Pozzi, D, Defilippi, P, Meier, J C, Brambilla, R, Turco, E, Rosenblum, K, Wanker, E E, Ziv, N E, Menna, E, Matteoli, M

“…Impairment of synaptic function can lead to neuropsychiatric disorders collectively referred to as synaptopathies. The SNARE protein SNAP-25 is implicated in…”
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REST-Dependent Presynaptic Homeostasis Induced by Chronic Neuronal Hyperactivity by Pecoraro-Bisogni, F., Lignani, Gabriele, Contestabile, A., Castroflorio, E., Pozzi, D., Rocchi, A., Prestigio, C., Orlando, M., Valente, P., Massacesi, M., Benfenati, F., Baldelli, Pietro

“…Homeostatic plasticity is a regulatory feedback response in which either synaptic strength or intrinsic excitability can be adjusted up or down to offset…”
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Correction: Brain mapping across 16 autism mouse models reveals a spectrum of functional connectivity subtypes by Zerbi, V., Pagani, M., Markicevic, M., Matteoli, M., Pozzi, D., Fagiolini, M., Bozzi, Y., Galbusera, A., Scattoni, M. L., Provenzano, G., Banerjee, A., Helmchen, F., Basson, M. A., Ellegood, J., Lerch, J. P., Rudin, M., Gozzi, A., Wenderoth, N.

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Improving the accuracy of pancreatic cancer clinical staging by exploitation of nanoparticle-blood interactions: A pilot study by Caputo, D., Cartillone, M., Cascone, C., Pozzi, D., Digiacomo, L., Palchetti, S., Caracciolo, G., Coppola, R.

“…Pancreatic ductal adenocarcinoma (PDAC) early diagnosis is  crucial  and new, cheap and user-friendly techniques for biomarker identification  are  needed…”
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Biophysics and protein corona analysis of Janus cyclodextrin-DNA nanocomplexes. Efficient cellular transfection on cancer cells by Martínez-Negro, M., Caracciolo, G., Palchetti, S., Pozzi, D., Capriotti, A.L., Cavaliere, C., Laganà, A., Ortiz Mellet, C., Benito, J.M., García Fernández, J.M., Aicart, E., Junquera, E.

“…The self-assembling processes underlining the capabilities of facially differentiated (“Janus”) polycationic amphiphilic cyclodextrins (paCDs) as non-viral…”
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Mechanistic Understanding of Gene Delivery Mediated by Highly Efficient Multicomponent Envelope-Type Nanoparticle Systems by Pozzi, D, Marchini, C, Cardarelli, F, Rossetta, A, Colapicchioni, V, Amici, A, Montani, M, Motta, S, Brocca, P, Cantù, L, Caracciolo, G

“…We packaged condensed DNA/protamine particles in multicomponent envelope-type nanoparticle systems (MENS) combining different molar fractions of the cationic…”
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The synaptic split of SNAP-25: Different roles in glutamatergic and GABAergic neurons? by Matteoli, M, Pozzi, D, Grumelli, C, Condliffe, S.B, Frassoni, C, Harkany, T, Verderio, C

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Pilot clinical study of carmustine associated with a lipid nanoemulsion in combination with vincristine and prednisone for the treatment of canine lymphoma by Lucas, S. R. R., Maranhão, R. C., Guerra, J. L., Coelho, B. M. P., Barboza, R., Pozzi, D. H. B.

“…A lipid nanoemulsion (LDE) resembling low‐density lipoprotein can target malignant tumours. In in vivo and clinical studies, association of chemotherapeutic…”
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A proteomics-based methodology to investigate the protein corona effect for targeted drug delivery by Pozzi, D, Caracciolo, G, Capriotti, A L, Cavaliere, C, Piovesana, S, Colapicchioni, V, Palchetti, S, Riccioli, A, Laganà, A

“…Here we introduce a proteomics methodology based on nanoliquid-chromatography tandem mass spectrometry (nanoLC/MS-MS) to investigate the "protein corona effect…”
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Analysis of SNAP-25 immunoreactivity in hippocampal inhibitory neurons during development in culture and in situ by Frassoni, C., Inverardi, F., Coco, S., Ortino, B., Grumelli, C., Pozzi, D., Verderio, C., Matteoli, M.

“…Synaptosomal associated protein of 25 kDa (SNAP-25) is a component of the soluble N-ethylmaleimide-sensitive fusion protein (NSF) attachment protein receptor…”
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Role of temperature-independent lipoplex-cell membrane interactions in the efficiency boost of multicomponent lipoplexes by Marchini, C, Pozzi, D, Montani, M, Alfonsi, C, Amici, A, Candeloro De Sanctis, S, Digman, M A, Sanchez, S, Gratton, E, Amenitsch, H, Fabbretti, A, Gualerzi, C O, Caracciolo, G

“…Multicomponent lipoplexes have recently emerged as especially promising transfection candidates, as they are from 10 to 100 times more efficient than binary…”
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UVB radiation induced effects on cells studied by FTIR spectroscopy by Di Giambattista, Lucia, Grimaldi, P., Gaudenzi, S., Pozzi, D., Grandi, M., Morrone, S., Silvestri, I., Congiu Castellano, A.

“…We have made a preliminary analysis of the results about the effects on tumoral cell line (lymphoid T cell line Jurkat) induced by UVB radiation (dose of…”
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Use of EPR and FTIR to detect biological effects of ultrasound and microbubbles on a fibroblast cell line by Pozzi, D., Fattibene, P., Viscomi, D., Di Giambattista, L., Grimaldi, P., Udroiu, I., Bedini, A., Giliberti, C., Palomba, R., Congiu Castellano, A.

“…Structural and functional effects of exposing murine fibroblasts (NIH 3T3) to therapeutic ultrasound at 1 MHz frequency are described. These bioeffects can be…”
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