Search Results - "D. Michelson"

Antiplatelet therapies for the treatment of cardiovascular disease by Michelson, Alan D

“…Key Points Antiplatelet therapy has been successful in reducing mortality and morbidity in acute myocardial infarction, which is the most common cause of death…”
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Methods for the Measurement of Platelet Function by Michelson, Alan D., MD

“…This article discusses the advantages and disadvantages of methods for the measurement of platelet function. The focus is on tests that can be used to monitor…”
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Electromagnetic interference shielding effectiveness of hybrid multifunctional Fe3O4/carbon nanofiber composite by Bayat, M., Yang, H., Ko, F.K., Michelson, D., Mei, A.

“…Electromagnetic interference shielding effectiveness (EMI SE) of multifunctional Fe3O4/carbon nanofiber composites in the X-band region (8.2–12.4 GHz) is…”
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Evidence Report: Genetic and metabolic testing on children with global developmental delay Report of the Quality Standards Subcommittee of the American Academy of Neurology and the Practice Committee of the Child Neurology Society by MICHELSON, D. J, SHEVELL, M. I, SHERR, E. H, MOESCHLER, J. B, GROPMAN, A. L, ASHWAL, S

“…To systematically review the evidence concerning the diagnostic yield of genetic and metabolic evaluation of children with global developmental delay or…”
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Mass Cytometry Reveals Distinct Platelet Subtypes in Healthy Subjects and Novel Alterations in Surface Glycoproteins in Glanzmann Thrombasthenia by Blair, Thomas A., Michelson, Alan D., Frelinger, Andrew L.

“…Mass cytometry (MC) uses mass spectrometry to simultaneously detect multiple metal-conjugated antibodies on single cells, thereby enabling the detailed study…”
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Clopidogrel Pharmacokinetics and Pharmacodynamics Vary Widely Despite Exclusion or Control of Polymorphisms ( CYP2C19 , ABCB1 , PON1 ), Noncompliance, Diet, Smoking, Co-Medications (Including Proton Pump Inhibitors), and Pre-Existent Variability in Platelet Function by Frelinger, Andrew L., PhD, Bhatt, Deepak L., MD, MPH, Lee, Ronald D., PhD, Mulford, Darcy J., PhD, Wu, Jingtao, PhD, Nudurupati, Sai, PhD, Nigam, Anu, MS, Lampa, Michael, BS, Brooks, Julie K., MS, Barnard, Marc R., MS, Michelson, Alan D., MD

“…Objectives This study sought to determine whether known genetic, drug, dietary, compliance, and lifestyle factors affecting clopidogrel absorption and…”
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The high-risk hip fracture patient and the palliative care consult: A retrospective study to investigate risks of complications and the utility of a palliative care consult in hip fracture patients undergoing surgical fixation by Schlauch, Adam M., Michelson, James D., Holleran, Amanda, Ames, Elizabeth

“…  Summary We evaluated the utility of a palliative care consult (PCC) in high-risk hip fracture patients. The main result was that a PCC reflects certain risk…”
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A Randomized, 2-Period, Crossover Design Study to Assess the Effects of Dexlansoprazole, Lansoprazole, Esomeprazole, and Omeprazole on the Steady-State Pharmacokinetics and Pharmacodynamics of Clopidogrel in Healthy Volunteers by Frelinger, Andrew L., PhD, Lee, Ronald D., PhD, Mulford, Darcy J., PhD, Wu, Jingtao, PhD, Nudurupati, Sai, PhD, Nigam, Anu, MS, Brooks, Julie K., MS, Bhatt, Deepak L., MD, MPH, Michelson, Alan D., MD

“…Objectives The aim of this study was to assess the effects of different proton pump inhibitors (PPIs) on the steady-state pharmacokinetics and pharmacodynamics…”
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Platelet function testing in cardiovascular diseases by Michelson, Alan D

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Platelet Function Monitoring in Patients With Coronary Artery Disease by Gurbel, Paul A., MD, Becker, Richard C., MD, Mann, Kenneth G., PhD, Steinhubl, Steven R., MD, Michelson, Alan D., MD

“…Platelet Function Monitoring in Patients With Coronary Artery Disease Paul A. Gurbel, Richard C. Becker, Kenneth G. Mann, Steven R. Steinhubl, Alan D…”
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Assessment of whole blood thrombosis in a microfluidic device lined by fixed human endothelium by Jain, Abhishek, van der Meer, Andries D., Papa, Anne-Laure, Barrile, Riccardo, Lai, Angela, Schlechter, Benjamin L., Otieno, Monicah A., Louden, Calvert S., Hamilton, Geraldine A., Michelson, Alan D., Frelinger, Andrew L., Ingber, Donald E.

“…The vascular endothelium and shear stress are critical determinants of physiological hemostasis and platelet function in vivo , yet current diagnostic and…”
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Pharmacodynamic effect and clinical efficacy of clopidogrel and prasugrel with or without a proton-pump inhibitor: an analysis of two randomised trials by O'Donoghue, Michelle L, Dr, Braunwald, Eugene, Prof, Antman, Elliott M, Prof, Murphy, Sabina A, MPH, Bates, Eric R, Prof, Rozenman, Yoseph, Prof, Michelson, Alan D, MD, Hautvast, Raymond W, MD, Ver Lee, Peter N, MD, Close, Sandra L, PhD, Shen, Lei, PhD, Mega, Jessica L, MD, Sabatine, Marc S, MD, Wiviott, Stephen D, MD

“…Summary Background Proton-pump inhibitors (PPIs) are often prescribed in combination with thienopyridines. Conflicting data exist as to whether PPIs diminish…”
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Pharmacodynamic assessment of platelet inhibition by prasugrel vs. clopidogrel in the TRITON-TIMI 38 trial by Michelson, Alan D., Frelinger, Andrew L., Braunwald, Eugene, Downey, William E., Angiolillo, Dominick J., Xenopoulos, Nicholas P., Jakubowski, Joseph A., Li, Youfu, Murphy, Sabina A., Qin, Jie, McCabe, Carolyn H., Antman, Elliott M., Wiviott, Stephen D.

“…Aims To examine the extent of platelet inhibition by prasugrel vs. clopidogrel in a TRITON-TIMI 38 substudy. Methods and results TRITON-TIMI 38 randomized…”
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Thromboprophylaxis for Children Post-Fontan Procedure: Insights From the UNIVERSE Study by McCrindle, Brian W, Michelson, Alan D, Van Bergen, Andrew H, Suzana Horowitz, Estela, Pablo Sandoval, Juan, Justino, Henri, Harris, Kevin C, Jefferies, John L, Miriam Pina, Liza, Peluso, Colleen, Nessel, Kimberly, Lu, Wentao, Li, Jennifer S

“…Background Patients with single-ventricle physiology who undergo the Fontan procedure are at risk for thrombotic events associated with significant morbidity…”
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High serum serotonin in sudden infant death syndrome by Haynes, Robin L., Frelinger, Andrew L., Giles, Emma K., Goldstein, Richard D., Tran, Hoa, Kozakewich, Harry P., Haas, Elisabeth A., Gerrits, Anja J., Mena, Othon J., Trachtenberg, Felicia L., Paterson, David S., Berry, Gerard T., Adeli, Khosrow, Kinney, Hannah C., Michelson, Alan D.

“…Sudden infant death syndrome (SIDS), the leading cause of postneonatal infant mortality, likely comprises heterogeneous disorders with the common phenotype of…”
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Soluble CD40 Ligand in Aspirin-Treated Patients Undergoing Cardiac Catheterization by Gremmel, Thomas, Frelinger, 3rd, Andrew L, Michelson, Alan D

“…Plasma soluble CD40 ligand (sCD40L) is mainly generated by cleavage of CD40L from the surface of activated platelets, and therefore considered a platelet…”
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The aryl hydrocarbon receptor directs hematopoietic progenitor cell expansion and differentiation by Smith, Brenden W., Rozelle, Sarah S., Leung, Amy, Ubellacker, Jessalyn, Parks, Ashley, Nah, Shirley K., French, Deborah, Gadue, Paul, Monti, Stefano, Chui, David H.K., Steinberg, Martin H., Frelinger, Andrew L., Michelson, Alan D., Theberge, Roger, McComb, Mark E., Costello, Catherine E., Kotton, Darrell N., Mostoslavsky, Gustavo, Sherr, David H., Murphy, George J.

“…The evolutionarily conserved aryl hydrocarbon receptor (AhR) has been studied for its role in environmental chemical-induced toxicity. However, recent studies…”
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Advances in antiplatelet therapy by Michelson, Alan D

“…Because of the central role of platelets in cardiovascular atherothrombosis, there is a well-established therapeutic role for antiplatelet therapy that…”
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Circulating monocyte-platelet aggregates are a more sensitive marker of in vivo platelet activation than platelet surface P-selectin : Studies in baboons, human coronary intervention, and human acute myocardial infarction by MICHELSON, Alan D, BARNARD, Marc R, KRUEGER, Lori A, VALERI, C. Robert, FURMAN, Mark I

“…Platelet surface P-selectin is considered the "gold standard" marker of platelet activation. Degranulated, P-selectin-positive platelets, however, aggregate…”
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Dysregulation of platelet serotonin, 14–3–3, and GPIX in sudden infant death syndrome by Frelinger, Andrew L., Haynes, Robin L., Goldstein, Richard D., Berny-Lang, Michelle A., Gerrits, Anja J., Riehs, Molly, Haas, Elisabeth A., Paunovic, Brankica, Mena, Othon J., Campman, Steven C., Milne, Ginger L., Sleeper, Lynn A., Kinney, Hannah C., Michelson, Alan D.

“…Sudden infant death syndrome (SIDS) is the leading cause of post-neonatal infant mortality, but the underlying cause(s) are unclear. A subset of SIDS infants…”
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