Search Results - "D. Menger, Michael"

Life is 3D: Boosting Spheroid Function for Tissue Engineering by Laschke, Matthias W, Menger, Michael D

“…Spheroids provide a 3D environment with intensive cell–cell contacts. As a result of their excellent regenerative properties and rapid progress in their…”
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Prevascularization in tissue engineering: Current concepts and future directions by Laschke, Matthias W., Menger, Michael D.

“…The survival of engineered tissue constructs during the initial phase after their implantation depends on the rapid development of an adequate vascularization…”
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The Hepatic Microcirculation: Mechanistic Contributions and Therapeutic Targets in Liver Injury and Repair by Vollmar, Brigitte, Menger, Michael D

“…Institute for Experimental Surgery, University of Rostock, Rostock; and Institute for Clinical and Experimental Surgery, University of Saarland, Homburg-Saar,…”
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Regulatory Mechanisms of Somatostatin Expression by Ampofo, Emmanuel, Nalbach, Lisa, Menger, Michael D, Laschke, Matthias W

“…Somatostatin is a peptide hormone, which most commonly is produced by endocrine cells and the central nervous system. In mammals, somatostatin originates from…”
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Thermosensitive Hydrogel Based on PEO–PPO–PEO Poloxamers for a Controlled In Situ Release of Recombinant Adeno‐Associated Viral Vectors for Effective Gene Therapy of Cartilage Defects by Madry, Henning, Gao, Liang, Rey‐Rico, Ana, Venkatesan, Jagadeesh K., Müller‐Brandt, Kathrin, Cai, Xiaoyu, Goebel, Lars, Schmitt, Gertrud, Speicher‐Mentges, Susanne, Zurakowski, David, Menger, Michael D., Laschke, Matthias W., Cucchiarini, Magali

“…Advanced biomaterial‐guided delivery of gene vectors is an emerging and highly attractive therapeutic solution for targeted articular cartilage repair,…”
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The gut microbiota: a puppet master in the pathogenesis of endometriosis? by Laschke, Matthias W., MD, PhD, Menger, Michael D., MD

“…Endometriosis is a frequent gynecologic disease with a complex, multifactorial cause. It is characterized by the cyclic estrogen-driven proliferation and…”
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Stimulation of TLR4 Attenuates Alzheimer's Disease-Related Symptoms and Pathology in Tau-Transgenic Mice by Qin, Yiren, Liu, Yang, Hao, Wenlin, Decker, Yann, Tomic, Inge, Menger, Michael D, Liu, Chunfeng, Fassbender, Klaus

“…Alzheimer's disease (AD) is characterized by intracellular neurofibrillary tangles. The primary component, hyperphosphorylated Tau (p-Tau), contributes to…”
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Protein Kinase CK2-A Putative Target for the Therapy of Diabetes Mellitus? by Ampofo, Emmanuel, Nalbach, Lisa, Menger, Michael D, Montenarh, Mathias, Götz, Claudia

“…Since diabetes is a global epidemic, the development of novel therapeutic strategies for the treatment of this disease is of major clinical interest. Diabetes…”
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Lingering Dynamics in Microvascular Blood Flow by Kihm, Alexander, Quint, Stephan, Laschke, Matthias W., Menger, Michael D., John, Thomas, Kaestner, Lars, Wagner, Christian

“…The microvascular networks in the body of vertebrates consist of the smallest vessels such as arterioles, capillaries, and venules. The flow of red blood cells…”
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Replacement in angiogenesis research: Studying mechanisms of blood vessel development by animal-free in vitro, in vivo and in silico approaches by Laschke, Matthias W., Gu, Yuan, Menger, Michael D.

“…Angiogenesis, the development of new blood vessels from pre-existing ones, is an essential process determining numerous physiological and pathological…”
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Nanofat Accelerates and Improves the Vascularization, Lymphatic Drainage and Healing of Full-Thickness Murine Skin Wounds by Limido, Ettore, Weinzierl, Andrea, Ampofo, Emmanuel, Harder, Yves, Menger, Michael D, Laschke, Matthias W

“…The treatment of wounds using the body's own resources is a promising approach to support the physiological regenerative process. To advance this concept, we…”
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Effect of endometriosis on the fecal bacteriota composition of mice during the acute phase of lesion formation by Hantschel, Josefine, Weis, Severin, Schäfer, Karl-Herbert, Menger, Michael D, Kohl, Matthias, Egert, Markus, Laschke, Matthias W

“…Accumulating evidence indicates that there is an interaction between the gut microbiota and endometriotic lesions. The new formation of these lesions is…”
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The Presence of Pre-Existing Endometriotic Lesions Promotes the Growth of New Lesions in the Peritoneal Cavity by Mihai, Ilinca T, Rudzitis-Auth, Jeannette, Menger, Michael D, Laschke, Matthias W

“…Endometriosis is a common gynecological disease which is characterized by endometriotic lesions outside the uterine cavity. In this study, we investigated…”
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Notch signaling controls sprouting angiogenesis of endometriotic lesions by Körbel, Christina, Gerstner, Miriam D., Menger, Michael D., Laschke, Matthias W.

“…Angiogenesis is essential for the engraftment and growth of endometriotic lesions. In this study, we analyzed whether this process is regulated by Notch…”
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Electrochemotherapy with intravenous, intratumoral, or combined administration of bleomycin in the treatment of colorectal hepatic metastases in a rat model by Spiliotis, Antonios E., Holländer, Sebastian, Wagenpfeil, Gudrun, Eisele, Robert, Nika, Spyridon, Mallis Kyriakides, Orestis, Laschke, Matthias W., Menger, Michael D., Glanemann, Matthias, Gäbelein, Gereon

“…Electrochemotherapy (ECT) combines the reversible electroporation (rEP) with intravenous (i.v.) or intratumoral (i.t.) administration of chemotherapeutic…”
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Lower oxygen saturation with higher rates of norepinephrine in bone fractures of polytrauma patients: a pilot study by Koch, Laura, Orth, Marcel, Fink, Tobias, Meiser, Andreas, Volk, Thomas, Menger, Michael D, Laschke, Matthias W, Pastor, Torsten, Knobe, Matthias, Pohlemann, Tim, Ganse, Bergita

“…Keywords: Multiple trauma, Catecholamines, Noradrenaline, Non-union, Fracture healing, Microcirculation, Perfusion, O2C, Injury, Mean arterial pressure…”
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Improvement of islet transplantation by the fusion of islet cells with functional blood vessels by Nalbach, Lisa, Roma, Leticia P, Schmitt, Beate M, Becker, Vivien, Körbel, Christina, Wrublewsky, Selina, Pack, Mandy, Später, Thomas, Metzger, Wolfgang, Menger, Maximilian M, Frueh, Florian S, Götz, Claudia, Lin, Haopeng, Manning Fox, Jocelyn E, MacDonald, Patrick E, Menger, Michael D, Laschke, Matthias W, Ampofo, Emmanuel

“…Pancreatic islet transplantation still represents a promising therapeutic strategy for curative treatment of type 1 diabetes mellitus. However, a limited…”
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Geraniol Suppresses Angiogenesis by Downregulating Vascular Endothelial Growth Factor (VEGF)/VEGFR-2 Signaling by Wittig, Christine, Scheuer, Claudia, Parakenings, Julia, Menger, Michael D, Laschke, Matthias W

“…Geraniol exerts several direct pharmacological effects on tumor cells and, thus, has been suggested as a promising anti-cancer compound. Because…”
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Modulation of Alzheimer's disease brain pathology in mice by gut bacterial depletion: the role of IL-17a by Hao, Wenlin, Luo, Qinghua, Tomic, Inge, Quan, Wenqiang, Hartmann, Tobias, Menger, Michael D, Fassbender, Klaus, Liu, Yang

“…Gut bacteria regulate brain pathology of Alzheimer's disease (AD) patients and animal models; however, the underlying mechanism remains unclear. In this study,…”
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Cancer-associated fibroblasts stimulate primary tumor growth and metastatic spread in an orthotopic prostate cancer xenograft model by Linxweiler, Johannes, Hajili, Turkan, Körbel, Christina, Berchem, Carolina, Zeuschner, Philip, Müller, Andreas, Stöckle, Michael, Menger, Michael D., Junker, Kerstin, Saar, Matthias

“…The unique microenvironment of the prostate plays a crucial role in the development and progression of prostate cancer (PCa). We examined the effects of…”
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