Search Results - "D. D. Sakaeva"

Targeted next-generation sequencing of 21 candidate genes in hereditary ovarian cancer patients from the Republic of Bashkortostan by Prokofyeva, D S, Mingazheva, E T, Valova, Ya V, Sakaeva, D D, Faishanova, R R, Nurgalieva, A Kh, Valiev, R R, Bogdanova, N, Dörk, T, Khusnutdinova, E K

“…About 5-10% of all ovarian cancer cases show familial clustering, and some 15-25% of familial ovarian cancer cases are mediated by high-penetrance mutations in…”
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CLINICAL CASE OF SUCCESFUL APPLICATION OF KADSYLA APPLICATION IN METASTATIC HER2 POSITIVE BREAST CANCER by Sakaeva, D. D.

“…A clinical case of trastuzumab emtansine in therapy line 4 in patient with metastatic HER2positive breast cancer is provided. After 10  courses of targeted…”
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Off-Label Drug Use in Oncology by Karabina, E. V., Sakaeva, D. D., Lipatov, O. N.

“…The off-label use of medicines is a routine clinical practice of oncology, especially in malignant-tumour patients with no treatment alternatives left when…”
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Prospects of application of inhibitors of PD-1/PD-L1 checkpoints in malignant tumors of the stomach and esophagogastric junction by Sakaeva, D. D., Melnikova, A. A.

“…Malignant tumors of the stomach and esophagogastric junction in advanced stages progress quite aggressively, and the prospects for treatment of these patients…”
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ALGORITHMS FOR MANAGEMENT OF PATIENTS WITH ADVERSE EVENTS ON THERAPY WITH TYROSINE KINASE INHIBITORS EGFR by D. D. SAKAEVA

“…The tyrosine kinase inhibitors (TKIs) of the epidermal receptor growth factor (EGFR) such as gefitinib, erlotinib and afatinib, are the standard first-line…”
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Lynch syndrome as a manifestation of hereditary ovarian cancer: a case report of treatment of a patient with platinum-sensitive recurrent ovarian cancer by R. R. Faiskhanova, D. D. Sakaeva

“…When we talk about hereditary ovarian cancer, we usually mean BRCA – associated cancer. Detection of hereditary ovarian cancer is important for the prevention…”
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A randomized, placebo-controlled phase 2 study of ganitumab or conatumumab in combination with FOLFIRI for second-line treatment of mutant KRAS metastatic colorectal cancer by Cohn, A.L., Tabernero, J., Maurel, J., Nowara, E., Sastre, J., Chuah, B.Y.S., Kopp, M.V., Sakaeva, D.D., Mitchell, E.P., Dubey, S., Suzuki, S., Hei, Y.-J., Galimi, F., McCaffery, I., Pan, Y., Loberg, R., Cottrell, S., Choo, S.-P.

“…Targeted agents presently available for mutant KRAS metastatic colorectal cancer (mCRC) are bevacizumab and aflibercept. We evaluated the efficacy and safety…”
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Anemia and iron deficiency in cancer patients: the role of intravenous iron supplements (a literature review) by Sakaeva, Dina D.

“…Anemia in patients with malignancies is a common disorder that has a markedly negative impact on quality of life and overall prognosis. The pathogenesis of…”
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Randomised phase III trial of vinflunine plus capecitabine versus capecitabine alone in patients with advanced breast cancer previously treated with an anthracycline and resistant to taxane by Martin, M., Campone, M., Bondarenko, I., Sakaeva, D., Krishnamurthy, S., Roman, L., Lebedeva, L., Vedovato, J.-C., Aapro, M.

“…Capecitabine is an approved standard therapy for anthracycline- and taxane-pretreated locally advanced or metastatic breast cancer (BC). Vinflunine has…”
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Resolution on the results of Advisory Board “Searching the effective methods of testing and treating patients with NSCLC caused by NTRK gene fusions by Artamonova, E. V., Breder, V. V., Vladimirova, L. Yu, Demidova, I. A., Imyanitov, E. N., Laktionov, К. К., Matrosova, M. P., Orlov, S. V., Rodionov, E. О., Sakaeva, D. D., Sekacheva, M. I., Smolin, A. V., Fadeeva, N. V., Filipenko, M. L.

“…The Advisory Board was held on December 24, 2021. The molecular genetic research lead specialists and national lead oncologists discussed issues of diagnosis…”
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Heterozygous mutation in fanconi anemia genes associated with hereditary breast cancer by Gordiev, M., Brovkina, O., Shigapova, L.H., Shagimardanova, E., Enikeev, R.F., Nikitin, A., Petkau, V., Aksarin, A., Ovchinnikova, E., Sakaeva, D.

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Specific Myocardial Lesion in a Patient with Diffuse Large B-Cell Lymphoma (a Case Report) by Sakaeva, D. D., Raevskaya, T. V., Valiakhmetova, Ch. Kh, Iskhakova, A. I.

“…Introduction. Myocardial lymphoma is one of the rarest lesion localizations among all the lymphoproliferative diseases. Regardless of the current lack of…”
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BREAST CANCER IN MEN IN THE REPUBLIC OF BASHKORTOSTAN by Sakaeva, D. D., Atnabaev, R. D., Ruchkin, V. V.

“…Breast cancer in men is 100 times less common than in women. The principles of treatment of breast cancer in men are still based on knowledge obtained during…”
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Multilineal treatment strategy of HER2-positive metastatic breast cancer (clinical case) by Nasretdinov, A.   F., Pushkarev, A.   V., Lipatov, O.  N. , Sultanbaeva, N.   I., Musin, Sh.   I., Menshikov, K.   V., Izmailov, A.   A., Pushkarev, V.   A., Galeev, M.   G., Muginov, R.   R., Valiakhmedov, R.   B., Sakaeva, D.   D., Sultanbaev, A.   V.

“…Descripton of metastatic HER2-positive breast cancer clinical case is introduced, multilineal strategy basing on clinical situation and disease features is…”
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STUDY OF THE ROLE OF MOLECULAR BIOLOGICAL MARKER FOR CLINICAL APPLICATION IN ONCOLOGY by Ch. Кh. Valiakhmetova, A. A. Garaishina, D. D. Sakaeva

“…This  article  analyzes   the   possibility  of   practical   application  of   the   most-studied molecular  biological markers  in the diagnosis and…”
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THE RESULTS OF CHEMORADIATION FOR CERVICAL CANCER USING FTORAFUR by D. D. Sakaeva, F. F. Mufazalov, A. A. Sultanbaev

“…The results of clinical and experimental studies  of the effectiveness of radiotherapy in combination with cisplatin and Ftorafur in the comparative analysis…”
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Immunofluorescent Assay of De Novo Vimentin Expression in Ovarian Cancer Tissues: Surgical Specimens vs Paraffin Embedded Tissue Blocks by Bogush, T. A., Basharina, A. A., Bogush, E. A., Grishanina, A. N., Sakaeva, D. M., Kirsanov, V. Yu, Davydov, M. M., Kosorukov, V. S.

“…The results of epithelial-mesenchymal transition analysis in serous ovarian cancer by the developed method of double immunofluorescent staining and flow…”
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Targeted therapy of brain metastases in patients with ALK-positive non-small cell lung cancer: A review by Sakaeva, Dina D., Bulavina, Irina S.

“…The data of recent years indicate the steady increase in the frequency of incidence of brain metastases in many localizations of malignant tumors. Non-small…”
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The immunosuppressive microenvironment of malignant gliomas by Borisov, K E, Sakaeva, D D

“…The dogma of the central nervous system (CNS) as an immune-privileged site has been substantially revised in recent years. CNS is an immunocompetent organ and…”
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The search for new candidate genes involved in ovarian cancer pathogenesis by exome sequencing by Prokofyeva, D. S., Mingajeva, E. T., Bogdanova, N. V., Faiskhanova, R. R., Sakaeva, D. D., Dörk, T., Khusnutdinova, E. K.

“…Ovarian cancer is one of the most insidious of tumors among gynecological cancers in the world. BRCA1 and BRCA2 mutations are associated with high risk of…”
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