Search Results - "D. Bernlohr"
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Correction to: Partitioning of adipose lipid metabolism by altered expression and function of PPAR isoforms after bariatric surgery
Published in International Journal of Obesity (01-09-2019)“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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Partitioning of adipose lipid metabolism by altered expression and function of PPAR isoforms after bariatric surgery
Published in International Journal of Obesity (01-02-2018)“…Background: Bariatric surgery remains the most effective treatment for reducing adiposity and eliminating type 2 diabetes; however, the mechanism(s)…”
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3
The Mammalian Fatty Acid-binding Protein Multigene Family: Molecular and Genetic Insights into Function
Published in Trends in Endocrinology & Metabolism (01-07-2000)“…Intracellular fatty acid-binding proteins associate with fatty acids and other hydrophobic biomolecules in an internal cavity, providing for solubilization and…”
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Intracellular lipid-binding proteins and their genes
Published in Annual review of nutrition (01-01-1997)“…Intracellular lipid-binding proteins are a family of low-molecular-weight single-chain polypeptides that form 1:1 complexes with fatty acids, retinoids, or…”
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Lipid-binding proteins modulate ligand-dependent trans-activation by peroxisome proliferator-activated receptors and localize to the nucleus as well as the cytoplasm
Published in Journal of lipid research (01-11-2000)“…Peroxisome proliferator-activated receptors (PPARs) are activated by a variety of fatty acids, eicosanoids, and hypolipidemic and insulin-sensitizing drugs…”
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The adipocyte lipid-binding protein at 1.6-A resolution. Crystal structures of the apoprotein and with bound saturated and unsaturated fatty acids
Published in The Journal of biological chemistry (15-04-1993)“…Crystals of the adipocyte lipid-binding protein which diffract to near atomic resolution have been obtained in Na/K phosphate buffer/precipitant system. The…”
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Targeted disruption of the adipocyte lipid-binding protein (aP2 protein) gene impairs fat cell lipolysis and increases cellular fatty acid levels
Published in Journal of lipid research (01-05-1999)“…The availability of mice containing an adipocyte lipid-binding protein (ALBP/aP2) gene disruption allowed for a direct examination of the presumed role of…”
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Identification of a functional peroxisome proliferator-responsive element in the murine fatty acid transport protein gene
Published in The Journal of biological chemistry (12-02-1999)“…Fatty acid transport protein (FATP), a plasma membrane protein implicated in controlling adipocyte transmembrane fatty acid flux, is up-regulated as a…”
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The Fatty Acid Transport Protein (FATP1) Is a Very Long Chain Acyl-CoA Synthetase
Published in The Journal of biological chemistry (17-12-1999)“…The primary sequence of the murine fatty acid transport protein (FATP1) is very similar to the multigene family of very long chain (C20-C26) acyl-CoA…”
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Mouse fatty acid transport protein 4 (FATP4): Characterization of the gene and functional assessment as a very long chain acyl-CoA synthetase
Published in Gene (30-05-2001)“…FATP4 (SLC27A4) is a member of the fatty acid transport protein (FATP) family, a group of evolutionarily conserved proteins that are involved in cellular…”
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11
Interaction of Rat Hormone-Sensitive Lipase with Adipocyte Lipid-Binding Protein
Published in Proceedings of the National Academy of Sciences - PNAS (11-05-1999)“…Hormone-sensitive lipase (HSL) is a cytosolic neutral lipase that functions as the rate-limiting enzyme for the mobilization of free fatty acids in adipose…”
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12
Purification of murine adipocyte lipid-binding protein. Characterization as a fatty acid- and retinoic acid-binding protein
Published in The Journal of biological chemistry (05-10-1988)“…An adipose-specific protein has been purified from murine 3T3-L1 adipocytes to greater than 98% homogeneity. A purification procedure was developed utilizing a…”
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13
Adipocyte lipid-binding protein complexed with arachidonic acid. Titration calorimetry and X-ray crystallographic studies
Published in The Journal of biological chemistry (14-10-1994)“…The association of the adipocyte lipid-binding protein (ALBP) with arachidonic acid (all cis, 20:4 delta 5,8,11,14) and oleic acid (cis, 18:1 delta 9) has been…”
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Characterization of the Functional Interaction of Adipocyte Lipid-binding Protein with Hormone-sensitive Lipase
Published in The Journal of biological chemistry (28-12-2001)“…Hormone-sensitive lipase (HSL) is an intracellular lipase that plays an important role in the hydrolysis of triacylglycerol in adipose tissue. HSL has been…”
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15
Synthesis of phosphotyrosine-containing peptides and their use as substrates for protein tyrosine phosphatases
Published in Biochemistry (Easton) (27-04-1993)“…Prior methods for the chemical synthesis of phosphotyrosine-containing peptides involved the incorporation of fully protected phosphoamino acids into the…”
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X-ray Crystallographic Structures of Adipocyte Lipid-Binding Protein Complexed with Palmitate and Hexadecanesulfonic Acid. Properties of Cavity Binding Sites
Published in Biochemistry (Easton) (01-04-1994)“…Adipocyte lipid-binding protein is a 14.6-kDa polypeptide that is responsible for the intracellular trafficking of fatty acids. Its structure previously has…”
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Crystal structure of recombinant murine adipocyte lipid-binding protein
Published in Biochemistry (Easton) (07-04-1992)“…Adipocyte lipid-binding protein (ALBP) is the adipocyte member of an intracellular hydrophobic ligand-binding protein family. ALBP is phosphorylated by the…”
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18
Evidence for an increase in transcription of specific mRNAs during differentiation of 3T3-L1 preadipocytes
Published in The Journal of biological chemistry (10-05-1985)“…Differentiation of 3T3-L1 preadipocytes in culture is accompanied by alterations in the abundance of several mRNAs and by the appearance of many new…”
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Regulation of fatty acid transporters in mammalian cells
Published in Progress in lipid research (2000)Get full text
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Modulation of ligand binding affinity of the adipocyte lipid-binding protein by selective mutation. Analysis in vitro and in situ
Published in The Journal of biological chemistry (15-04-1993)“…The crystal structure of the adipocyte lipid-binding protein (ALBP) with coordinated fatty acid shows the hydrophobic ligand bound within a water-filled…”
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