Search Results - "D’agostini, T."

Association of treatment adherence with real-life VA outcomes in AMD, DME, and BRVO patients by Ehlken, Christoph, Helms, Mandy, Böhringer, Daniel, Agostini, Hansjürgen T, Stahl, Andreas

“…Real-life clinical outcomes of patients treated with anti-VEGF drugs for neovascular age-related macular degeneration (nAMD), diabetic macular edema (DME), or…”
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Gene expression profiling in a mouse model of retinal vein occlusion induced by laser treatment reveals a predominant inflammatory and tissue damage response by Martin, Gottfried, Conrad, David, Cakir, Bertan, Schlunck, Günther, Agostini, Hansjürgen T

“…Retinal vein occlusion (RVO) has been investigated in several laser-induced animal models using pigs, rabbits and rats. However, laser-induced RVO has been…”
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Viral S protein histochemistry reveals few potential SARS-CoV-2 entry sites in human ocular tissues by Martin, Gottfried, Wolf, Julian, Lapp, Thabo, Agostini, Hansjürgen T., Schlunck, Günther, Auw-Hädrich, Claudia, Lange, Clemens A. K.

“…Despite the reported low expression of the primary SARS-CoV-2 receptor ACE2 in distinct ocular tissues, some clinical evidence suggests that SARS-CoV-2 can…”
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Increased expression of angiogenic and inflammatory proteins in the vitreous of patients with ischemic central retinal vein occlusion by Ehlken, Christoph, Grundel, Bastian, Michels, Daniel, Junker, Bernd, Stahl, Andreas, Schlunck, Günther, Hansen, Lutz L, Feltgen, Nicolas, Martin, Gottfried, Agostini, Hansjürgen T, Pielen, Amelie

“…Central retinal vein occlusion (CRVO) is a common disease characterized by a disrupted retinal blood supply and a high risk of subsequent vision loss due to…”
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Methylglyoxal and high glucose inhibit VEGFR2 phosphorylation at specific tyrosine residues by Betting, Fabian, Schlunck, Günther, Agostini, Hansjürgen T., Martin, Gottfried

“…Diabetes is characterized by hyperglycemia and a significant risk of vascular complications. Vascular endothelial growth factor (VEGF) and its main receptor…”
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Simultaneous Rhinoseptoplasty and Orthognathic Surgery: Outcome Analysis of 250 Consecutive Patients Using a Modified Le Fort I Osteotomy by Raffaini, M., Cocconi, R., Spinelli, G., Agostini, T.

“…Background The purpose of the present study was to assess the safety and efficacy of both functional intranasal procedures and cosmetic rhinoplasty combined…”
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A safety review and meta-analyses of bevacizumab and ranibizumab: off-label versus goldstandard by Schmucker, Christine, Ehlken, Christoph, Agostini, Hansjuergen T, Antes, Gerd, Ruecker, Gerta, Lelgemann, Monika, Loke, Yoon K

“…We set out a systemic review to evaluate whether off-label bevacizumab is as safe as licensed ranibizumab, and whether bevacizumab can be justifiably offered…”
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Hyperoxia causes reduced density of retinal astrocytes in the central avascular zone in the mouse model of oxygen-induced retinopathy by Bucher, Felicitas, Stahl, Andreas, Agostini, Hansjürgen T., Martin, Gottfried

“…The mouse model of oxygen-induced retinopathy (OIR) is commonly used to investigate various aspects of the pathogenesis of the retinopathy of prematurity (ROP)…”
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TREATMENT OF NEOVASCULAR AGE-RELATED MACULAR DEGENERATION PATIENTS WITH VASCULAR ENDOTHELIAL GROWTH FACTOR INHIBITORS IN EVERYDAY PRACTICE: Identification of Health Care Constraints in Germany-The PONS Study by Ehlken, Christoph, Wilke, Thomas, Bauer-Steinhusen, Ulrike, Agostini, Hansjürgen T, Hasanbasic, Zoran, Müller, Sabrina

“…The PONS study was conceived to analyze the extent of nonpersistence (NP) and nonadherence (NA) in the treatment of patients with neovascular age-related…”
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Evaluation of reference genes for gene expression analysis by real-time quantitative PCR (qPCR) in three stingless bee species (Hymenoptera: Apidae: Meliponini) by Freitas, Flávia C. P., Depintor, Thiago S., Agostini, Lucas T., Luna-Lucena, Danielle, Nunes, Francis M. F., Bitondi, Márcia M. G., Simões, Zilá L. P., Lourenço, Anete P.

“…Stingless bees are generalist pollinators distributed through the pantropical region. There is growing evidence that their wild populations are experiencing…”
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Arteriovenous crossing in retinal vessels of mice, rats, and pigs by Martin, Gottfried, Wefelmeyer, Kira L, Bucher, Felicitas, Schlunck, Günther, Agostini, Hansjürgen T

“…Retinal vein occlusions (RVOs) are a common disease, but there are no animal models for spontaneous RVO formation. The critical sites of predilection,…”
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Activation of retinal microglia rather than microglial cell density correlates with retinal neovascularization in the mouse model of oxygen-induced retinopathy by Fischer, Franziska, Martin, Gottfried, Agostini, Hansjürgen T

“…Retinal neovascularization has been intensively investigated in the mouse model of oxygen-induced retinopathy (OIR). Here, we studied the contribution of…”
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Levels of VEGF but not VEGF165b are Increased in the Vitreous of Patients With Retinal Vein Occlusion by Ehlken, Christoph, Rennel, Emma S, Michels, Daniel, Grundel, Bastian, Pielen, Amelie, Junker, Bernd, Stahl, Andreas, Hansen, Lutz L, Feltgen, Nicolas, Agostini, Hansjürgen T, Martin, Gottfried

“…Purpose To determine the concentration of the pro-angiogenic vascular endothelial growth factor VEGF165 (VEGF) and the anti-angiogenic VEGF165b in vitreous…”
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Semaphorin 3F forms an anti-angiogenic barrier in outer retina by Buehler, Anima, Sitaras, Nicholas, Favret, Sandra, Bucher, Felicitas, Berger, Stefanie, Pielen, Amelie, Joyal, Jean-Sebastian, Juan, Aimee M., Martin, Gottfried, Schlunck, Guenther, Agostini, Hansjürgen T., Klagsbrun, Michael, Smith, Lois E.H., Sapieha, Przemyslaw, Stahl, Andreas

“…•The outer retina is physiologically avascular.•Sema3F is expressed almost exclusively in photoreceptors and RPE of the outer retina.•Sema3F inhibits sprouting…”
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Closed reduction of the isolated anterior frontal sinus fracture via percutaneous screw placement by Spinelli, G, Lazzeri, D, Arcuri, F, Agostini, T

“…Abstract Fractures of the frontal sinus are a common maxillofacial trauma and constitute 5–15% of all maxillofacial fractures. Conventional surgical approaches…”
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Value of Optical Coherence Tomography Angiography Imaging in Diagnosis and Treatment of Hemangioblastomas in von Hippel-Lindau Disease by Lang, Stefan J, Cakir, Bertan, Evers, Charlotte, Ludwig, Franziska, Lange, Clemens A K, Agostini, Hansjürgen T

“…The introduction of optical coherence tomography angiography (OCTA) provides new insights into the retinal vasculature. The aim of this study was to explore…”
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Potential selection bias in candidates for stereotactic radiotherapy for neovascular AMD by Ehlken, Christoph, Böhringer, Daniel, Agostini, Hansjürgen T., Grundel, Bastian, Stech, Milena

“…Purpose Stereotactic radiotherapy (SRT, IRay) was able to reduce the need for intravitreal injections of anti-VEGF (IVI) in patients with neovascular AMD…”
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Highly potent VEGF-A-antagonistic DARPins as anti-angiogenic agents for topical and intravitreal applications by Stahl, Andreas, Stumpp, Michael T., Schlegel, Anja, Ekawardhani, Savira, Lehrling, Christina, Martin, Gottfried, Gulotti-Georgieva, Maya, Villemagne, Denis, Forrer, Patrik, Agostini, Hansjürgen T., Binz, H. Kaspar

“…The next-generation ophthalmic anti-VEGF therapeutics must aim at being superior to the currently available agents with regard to potency and improved drug…”
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Choroidal neovascularization reduced by targeted drug delivery with cationic liposome-encapsulated paclitaxel or targeted photodynamic therapy with verteporfin encapsulated in cationic liposomes by Gross, Nikolai, Ranjbar, Mahdy, Evers, Charlotte, Hua, Jing, Martin, Gottfried, Schulze, Brita, Michaelis, Uwe, Hansen, Lutz L, Agostini, Hansjürgen T

“…Intravitreal antivascular endothelial growth factor (anti-VEGF) application has revolutionized the treatment of choroidal neovascularization (CNV), a hallmark…”
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Intravitreal bevacizumab (Avastin) versus ranibizumab (Lucentis) for the treatment of age-related macular degeneration: a safety review by Schmucker, Christine, Loke, Yoon K, Ehlken, Christoph, Agostini, Hansjuergen T, Hansen, Lutz L, Antes, Gerd, Lelgemann, Monika

“…To conduct a systematic review in order to compare adverse effects (AE) and the reporting of harm in randomised controlled trials (RCTs) and non-RCTs…”
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