Search Results - "D’Urzo, Annalisa"

Molecular Basis for Structural Heterogeneity of an Intrinsically Disordered Protein Bound to a Partner by Combined ESI-IM-MS and Modeling by D’Urzo, Annalisa, Konijnenberg, Albert, Rossetti, Giulia, Habchi, Johnny, Li, Jinyu, Carloni, Paolo, Sobott, Frank, Longhi, Sonia, Grandori, Rita

“…Intrinsically disordered proteins (IDPs) form biologically active complexes that can retain a high degree of conformational disorder, escaping structural…”
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The conformational response to Zn(II) and Ni(II) binding of Sporosarcina pasteurii UreG, an intrinsically disordered GTPase by D’Urzo, Annalisa, Santambrogio, Carlo, Grandori, Rita, Ciurli, Stefano, Zambelli, Barbara

“…Urease is an essential Ni(II) enzyme involved in the nitrogen metabolism of bacteria, plants and fungi. Ni(II) delivery into the enzyme active site requires…”
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Application of an ESI-QTOF method for the detailed characterization of GSK-3β inhibitors by De Simone, Angela, Fiori, Jessica, Naldi, Marina, D’Urzo, Annalisa, Tumiatti, Vincenzo, Milelli, Andrea, Andrisano, Vincenza

“…[Display omitted] •Determination of GSK-3β activity and inhibition by monitoring GSM phosphorylation by ESI-MS.•Identification of a structural modification on…”
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Direct determination of GSK-3β activity and inhibition by UHPLC-UV–vis diode arrays detector (DAD) by D’Urzo, Annalisa, De Simone, Angela, Fiori, Jessica, Naldi, Marina, Milelli, Andrea, Andrisano, Vincenza

“…[Display omitted] •A new and very fast liquid chromatographic analysis for the direct determination of GSK 3β activity and inhibition has been developed and…”
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Site-specific quantification of lysine acetylation in the N-terminal tail of histone H4 using a double-labelling, targeted UHPLC MS/MS approach by D’Urzo, Annalisa, Boichenko, Alexander P., van den Bosch, Thea, Hermans, Jos, Dekker, Frank, Andrisano, Vincenza, Bischoff, Rainer

“…We developed a targeted liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for the site-specific quantification of lysine acetylation in the…”
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Characterization of the Genome of the Dairy Lactobacillus helveticus Bacteriophage ΦAQ113 by ZAGO, Miriam, SCALTRITI, Erika, FELSANI, Armando, D'URZO, Annalisa, MOLES, Anna, CLAUDE, Jean-Baptiste, GRANDORI, Rita, RAMONI, Roberto, GIRAFFA, Giorgio, ROSSETTI, Lia, GUFFANTI, Alessandro, ARMIENTO, Angelarita, FORNASARI, Maria Emanuela, GROLLI, Stefano, CARMINATI, Domenico, BRINI, Elena, PAVAN, Paolo

“…Classifications Services AEM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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An Efficient Method for Vault Nanoparticle Conjugation with Finely Adjustable Amounts of Antibodies and Small Molecules by Tomaino, Giulia, Pantaleoni, Camilla, D'Urzo, Annalisa, Santambrogio, Carlo, Testa, Filippo, Ciprandi, Matilde, Cotugno, Davide, Frascotti, Gianni, Vanoni, Marco, Tortora, Paolo

“…Vaults are eukaryotic ribonucleoproteins consisting of 78 copies of the major vault protein (MVP), which assemble into a nanoparticle with an about 60 nm…”
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Catalytic competence of the Ras–GEF domain of hSos1 requires intra-REM domain interactions mediated by Phenylalanine 577 by Sacco, Elena, Metalli, David, Busti, Stefano, Fantinato, Sonia, D’Urzo, Annalisa, Mapelli, Valeria, Alberghina, Lilia, Vanoni, Marco

“…The Ras-specific guanine nucleotide exchange region of hSos1 consists of two consecutive domains: the catalytic core (residues 742–1024) contains all residues…”
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HspB8 interacts with BAG3 in a “native‐like” conformation forming a complex that displays chaperone‐like activity by Sciandrone, Barbara, Ami, Diletta, D'Urzo, Annalisa, Angeli, Elena, Relini, Annalisa, Vanoni, Marco, Natalello, Antonino, Regonesi, Maria Elena

“…The HspB8‐BAG3 complex plays an important role in the protein quality control acting alone or within multi‐components complexes. To clarify the mechanism…”
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Interactions of ataxin-3 with its molecular partners in the protein machinery that sorts protein aggregates to the aggresome by Bonanomi, Marcella, Mazzucchelli, Serena, D’Urzo, Annalisa, Nardini, Marco, Konarev, Petr V., Invernizzi, Gaetano, Svergun, Dmitri I., Vanoni, Marco, Regonesi, Maria Elena, Tortora, Paolo

“…Ataxin-3 (AT3) is the protein that triggers the inherited neurodegenerative disorder spinocerebellar ataxia type 3 when its polyglutamine (polyQ) stretch close…”
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Selective cytotoxicity of a bicyclic Ras inhibitor in cancer cells expressing K-RasG13D by Palmioli, Alessandro, Sacco, Elena, Airoldi, Cristina, Di Nicolantonio, Federica, D’Urzo, Annalisa, Shirasawa, Senji, Sasazuki, Takehiko, Di Domizio, Alessandro, De Gioia, Luca, Martegani, Enzo, Bardelli, Alberto, Peri, Francesco, Vanoni, Marco

“…Mutation of RAS genes is a critical event in the pathogenesis of different human tumors and in some developmental disorders. Here we present an…”
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Proteomic and biochemical analyses unveil tight interaction of ataxin-3 with tubulin by Mazzucchelli, Serena, De Palma, Antonella, Riva, Matteo, D’Urzo, Annalisa, Pozzi, Chiara, Pastori, Valentina, Comelli, Francesca, Fusi, Paola, Vanoni, Marco, Tortora, Paolo, Mauri, Pierluigi, Regonesi, Maria Elena

“…Ataxin-3 consists of an N-terminal globular Josephin domain and an unstructured C-terminal region containing a stretch of consecutive glutamines that triggers…”
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Targeting protein aggregation using a cocoa-bean shell extract to reduce α-synuclein toxicity in models of Parkinson's disease by Tripodi, Farida, Lambiase, Alessia, Moukham, Hind, Spandri, Giorgia, Brioschi, Maura, Falletta, Ermelinda, D'Urzo, Annalisa, Vai, Marina, Abbiati, Francesco, Pagliari, Stefania, Salvo, Andrea, Spano, Mattia, Campone, Luca, Labra, Massimo, Coccetti, Paola

“…Neurodegenerative diseases are among the major challenges in modern medicine, due to the progressive aging of the world population. Among these, Parkinson's…”
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Extracting structural information from charge-state distributions of intrinsically disordered proteins by non-denaturing electrospray-ionization mass spectrometry by Testa, Lorenzo, Brocca, Stefania, Santambrogio, Carlo, D'Urzo, Annalisa, Habchi, Johnny, Longhi, Sonia, Uversky, Vladimir N, Grandori, Rita

“…Intrinsically disordered proteins (IDPs) exert key biological functions but tend to escape identification and characterization due to their high structural…”
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Selective cytotoxicity of a bicyclic Ras inhibitor in cancer cells expressing K-Ras(G13D) by Palmioli, Alessandro, Sacco, Elena, Airoldi, Cristina, Di Nicolantonio, Federica, D'Urzo, Annalisa, Shirasawa, Senji, Sasazuki, Takehiko, Di Domizio, Alessandro, De Gioia, Luca, Martegani, Enzo, Bardelli, Alberto, Peri, Francesco, Vanoni, Marco

“…Mutation of RAS genes is a critical event in the pathogenesis of different human tumors and in some developmental disorders. Here we present an…”
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Characterization of the genome of the dairy Lactobacillus helveticus bacteriophage {Phi}AQ113 by Zago, Miriam, Scaltriti, Erika, Rossetti, Lia, Guffanti, Alessandro, Armiento, Angelarita, Fornasari, Maria Emanuela, Grolli, Stefano, Carminati, Domenico, Brini, Elena, Pavan, Paolo, Felsani, Armando, D'Urzo, Annalisa, Moles, Anna, Claude, Jean-Baptiste, Grandori, Rita, Ramoni, Roberto, Giraffa, Giorgio

“…The complete genomic sequence of the dairy Lactobacillus helveticus bacteriophage ΦAQ113 was determined. Phage ΦAQ113 is a Myoviridae bacteriophage with an…”
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Glucose-Derived Ras Pathway Inhibitors: Evidence of Ras-Ligand Binding and Ras-GEF (Cdc25) Interaction Inhibition by Airoldi, Cristina, Palmioli, Alessandro, D'Urzo, Annalisa, Colombo, Sonia, Vanoni, Marco, Martegani, Enzo, Peri, Francesco

“…Too complex to change. New glucose‐derived phenylhydroxylamines inhibit nucleotide exchange on human Ras. NMR and SPR experiments indicated that the Ras–GEF…”
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