Search Results - "D’Errico, Eustachio"
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Dysregulation of MicroRNAs and Target Genes Networks in Peripheral Blood of Patients With Sporadic Amyotrophic Lateral Sclerosis
Published in Frontiers in molecular neuroscience (28-08-2018)“…Amyotrophic lateral sclerosis (ALS) is a progressive and fatal neurodegenerative disease. While genetics and other factors contribute to ALS pathogenesis,…”
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Magnetic resonance metrics to evaluate the effect of therapy in amyotrophic lateral sclerosis: the experience with edaravone
Published in Journal of neurology (01-09-2021)“…Background Edaravone was approved as a new treatment for amyotrophic lateral sclerosis (ALS), although there are different opinions on its effectiveness…”
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Nusinersen safety and effects on motor function in adult spinal muscular atrophy type 2 and 3
Published in Journal of neurology, neurosurgery and psychiatry (01-11-2020)“…ObjectiveTo retrospectively investigate safety and efficacy of nusinersen in a large cohort of adult Italian patients with spinal muscular atrophy…”
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Motor-evoked potentials in amyotrophic lateral sclerosis: potential implications in detecting subclinical UMN involvement in lower motor neuron phenotype
Published in Journal of neurology (01-12-2020)“…Background In amyotrophic lateral sclerosis (ALS), the involvement of lower motor neuron is well defined by electromyography, whereas a reliable marker of…”
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An early Transcriptomic Investigation in Adult Patients with Spinal Muscular Atrophy Under Treatment with Nusinersen
Published in Journal of molecular neuroscience (26-09-2024)“…Spinal muscular atrophy (SMA) is a rare degenerative disorder with loss of motor neurons caused by mutations in the SMN1 gene. Nusinersen, an antisense…”
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Nerve conduction study on the split-hand plus index in Amyotrophic lateral sclerosis: correlations with lower motor neuron impairment
Published in Neurological sciences (01-10-2024)“…Introduction In the arms of patients with Amyotrophic lateral sclerosis (ALS) two peculiar patterns of dissociated muscular atrophy have been described: the…”
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Cerebrospinal Fluid and Clinical Profiles in Adult Type 2–3 Spinal Muscular Atrophy Patients Treated with Nusinersen: An 18-Month Single-Centre Experience
Published in Clinical drug investigation (01-09-2021)“…Background and Objectives Nusinersen was approved as the first disease-modifying therapy in spinal muscular atrophy (SMA). Our aim was to analyse…”
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Nutritional prognostic factors for survival in amyotrophic lateral sclerosis patients undergone percutaneous endoscopic gastrostomy placement
Published in Amyotrophic lateral sclerosis and frontotemporal degeneration (02-10-2019)“…Objective: There are conflicting data on nutritional factors influencing survival in amyotrophic lateral sclerosis (ALS) patients after percutaneous endoscopic…”
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Acoustic Voice Analysis as a Useful Tool to Discriminate Different ALS Phenotypes
Published in Biomedicines (31-08-2023)“…Approximately 80–96% of people with amyotrophic lateral sclerosis (ALS) become unable to speak during the disease progression. Assessing upper and lower motor…”
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Medulla oblongata volume as a promising predictor of survival in amyotrophic lateral sclerosis
Published in NeuroImage clinical (01-01-2022)“…•Brainstem volumes reflect the disease severity expressed as ALSFRS-r (total score and its bulbar and spinal subscores).•Medulla oblongata volume demonstrated…”
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Guillain‐Barré syndrome associated with inappropriate secretion of antidiuretic hormone following SARS‐CoV‐2 infection: A case‐report
Published in Clinical case reports (01-10-2021)“…In a system already preconditioned by previous damage, as results of the cytokine release syndrome complicating the COVID‐19 disease, a small trigger may be…”
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An exploratory study of serum urate levels in patients with amyotrophic lateral sclerosis
Published in Journal of neurology (01-02-2011)“…Urate is a natural antioxidant, and high serum urate levels could be protective against the development of amyotrophic lateral sclerosis (ALS). To determine if…”
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Pseudobulbar affect (PBA) in an incident ALS cohort: results from the Apulia registry (SLAP)
Published in Journal of neurology (01-02-2016)“…The aim of this study is to investigate the frequency and the clinical correlations of pseudobulbar affect (PBA) in a population-based incident cohort of ALS…”
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Adherence to riluzole in patients with amyotrophic lateral sclerosis: an observational study
Published in Neuropsychiatric disease and treatment (01-01-2018)“…Riluzole is the first drug approved to treat amyotrophic lateral sclerosis (ALS). Recently, an oral suspension (OS) of riluzole was made available. Thus, the…”
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Corrigendum: Dysregulation of MicroRNAs and Target Genes Networks in Peripheral Blood of Patients With Sporadic Amyotrophic Lateral Sclerosis
Published in Frontiers in molecular neuroscience (10-01-2019)“…[This corrects the article DOI: 10.3389/fnmol.2018.00288.]…”
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Cortical thinning and clinical heterogeneity in amyotrophic lateral sclerosis
Published in PloS one (20-11-2013)“…Amyotrophic lateral sclerosis (ALS) has heterogeneous clinical features that could be translated into specific patterns of brain atrophy. In the current study…”
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Diagnostic and prognostic power of CSF Tau in amyotrophic lateral sclerosis
Published in Journal of neurology (01-10-2018)“…Background Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease that still lacks reliable diagnostic biomarkers. This study aims to…”
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A Clinical Scale for Rating the Severity of Bulbar Lower Motor Neuron Dysfunction in Amyotrophic Lateral Sclerosis
Published in Biomedicines (01-07-2023)“…Amyotrophic lateral sclerosis (ALS) is characterized by the progressive loss of upper (UMN) and lower motor neurons (LMN) in four different body regions…”
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Mapping lower-limbs muscle vulnerability in patients with ALS: The role of upper and lower motor neurons
Published in Journal of the neurological sciences (15-07-2024)“…Several studies have reported disproportionate wasting of the flexor muscles of the lower limbs (LL) compared to the extensors in patients with amyotrophic…”
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