Search Results - "D’Emanuele, Antony"

Carbon Nanotubes in Cancer Therapy and Drug Delivery by Elhissi, Abdelbary M. A., Ahmed, Waqar, Hassan, Israr Ul, Dhanak, Vinod. R., D'Emanuele, Antony

“…Carbon nanotubes (CNTs) have been introduced recently as a novel carrier system for both small and large therapeutic molecules. CNTs can be functionalized…”
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The use of a dendrimer-propranolol prodrug to bypass efflux transporters and enhance oral bioavailability by D'Emanuele, Antony, Jevprasesphant, Rachaneekorn, Penny, Jeffrey, Attwood, David

“…The aim of the study was to determine the effects on the transport of propranolol across monolayers of the human colon adenocarcinoma cell line, Caco-2, of…”
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Transport of dendrimer nanocarriers through epithelial cells via the transcellular route by Jevprasesphant, Rachaneekorn, Penny, Jeffrey, Attwood, David, D'Emanuele, Antony

“…The mechanism of transport of G3 PAMAM and surface-modified (with lauroyl chains) G3 PAMAM dendrimer nanocarriers across Caco-2 cell monolayers has been…”
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PAMAM dendrimers as aerosol drug nanocarriers for pulmonary delivery via nebulization by Nasr, Maha, Najlah, Mohammad, D’Emanuele, Antony, Elhissi, Abdelbary

“…Polyamidoamine (PAMAM) dendrimers were evaluated as nanocarriers for pulmonary delivery of the model poorly soluble anti-asthma drug beclometasone dipropionate…”
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Extraction and RP-HPLC determination of taxol in rat plasma, cell culture and quality control samples by Tekade, Rakesh Kumar, D'Emanuele, Antony, Elhissi, Abdelbary, Agrawal, Ashish, Jain, Anurekha, Arafat, Basel Tawfiq, Jain, Narendra Kumar

“…A rapid, sensitive, selective and validated reverse phase high-performance liquid chromatography （RP-HPLC） method for the estimation of paclitaxel in…”
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RNAi-combined nano-chemotherapeutics to tackle resistant tumors by Tekade, Rakesh Kumar, Tekade, Muktika, Kesharwani, Prashant, D’Emanuele, Antony

“…•Nanotechnology can protect siRNA against RNAse degradation.•siRNA adopts an alternative pathway to knock genes with high specificity to cure cancer.•An ideal…”
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Surface Modification of PAMAM Dendrimers Modulates the Mechanism of Cellular Internalization by Saovapakhiran, Angkana, D’Emanuele, Antony, Attwood, David, Penny, Jeffrey

“…The aim of this study was to investigate the influence of dendrimer surface properties on cellular internalization and intracellular trafficking in the human…”
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Solubility enhancement of paclitaxel using a linear-dendritic block copolymer by Zhou, Zhengyuan, D’Emanuele, Antony, Attwood, David

“…The solubilising capacities of micelles of a linear-dendritic copolymer (BE-PAMAM), formed by conjugating the poly(butylene oxide) (B)–poly(ethylene oxide) (E)…”
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Delivery of paclitaxel across cellular barriers using a dendrimer-based nanocarrier by Teow, Huey Minn, Zhou, Zhengyuan, Najlah, Mohammad, Yusof, Siti R., Abbott, N. Joan, D’Emanuele, Antony

“…The aim of this study was to investigate the ability of a third-generation (G3) polyamidoamine (PAMAM) dendrimer-based carrier to enhance the permeability of…”
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In Vitro Evaluation of Third Generation PAMAM Dendrimer Conjugates by Najlah, Mohammad, Freeman, Sally, Khoder, Mouhamad, Attwood, David, D'Emanuele, Antony

“…The present study compares the use of high generation G3 and low generation G0 Polyamidoamine (PAMAM) dendrimers as drug carriers of naproxen (NAP), a poorly…”
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In vitro evaluation of dendrimer prodrugs for oral drug delivery by Najlah, Mohammad, Freeman, Sally, Attwood, David, D’Emanuele, Antony

“…Dendrimer-based prodrugs were used to enhance the transepithelial permeability of naproxen, a low solubility model drug. The stability of the…”
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Preparation of core-crosslinked linear-dendritic copolymer micelles with enhanced stability and their application for drug solubilisation by Zhou, Zhengyuan, Forbes, Robert T., D’Emanuele, Antony

“…[Display omitted] In this study we explore the preparation of core-crosslinked micelles of linear-dendritic methoxy-poly(ethylene glycol)…”
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Recent Developments of Nanostructures for the Ocular Delivery of Natural Compounds by Razavi, Malihe Sadat, Ebrahimnejad, Pedram, Fatahi, Yousef, D'Emanuele, Antony, Dinarvand, Rassoul

“…Ocular disorders comprising various diseases of the anterior and posterior segments are considered as the main reasons for blindness. Natural products have…”
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Effect of D-Sorbitol on the Thermal Gelation of Methylcellulose Formulations for Drug Delivery by Itoh, Kunihiko, Hatakeyama, Tomoaki, Kimura, Tomoki, Shimoyama, Tetsuya, Miyazaki, Shozo, D'Emanuele, Antony, Attwood, David

“…The aim of this study was to examine the effect of D-sorbitol on the gelation characteristics of methylcellulose in aqueous solution. The addition of…”
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Synthesis, characterization and stability of dendrimer prodrugs by Najlah, Mohammad, Freeman, Sally, Attwood, David, D’Emanuele, Antony

“…The design, synthesis and characterization of a series of zero generation (G0) PAMAM dendrimer-based prodrugs for the potential enhancement of drug solubility…”
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Crossing cellular barriers using dendrimer nanotechnologies by Najlah, Mohammad, D’Emanuele, Antony

“…Dendrimers represent a class of polymers characterised by their well-defined structure, with a high degree of molecular uniformity and low polydispersity. They…”
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Recent advances in exosome-based nanovehicles as RNA interference therapeutic carriers by Maheshwari, Rahul, Tekade, Muktika, Gondaliya, Piyush, Kalia, Kiran, D'Emanuele, Antony, Tekade, Rakesh Kumar

“…RNA interference (RNAi) therapeutics (siRNA, miRNA, etc.) represent an emerging medicinal remedy for a variety of ailments. However, their low serum stability…”
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Dendrimer–drug interactions by D'Emanuele, Antony, Attwood, David

“…The interaction between drugs and dendrimers is reviewed with particular reference to the entrapment of drugs within the dendrimer architecture and the…”
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Synthesis and Micellization of Linear−Dendritic Copolymers and Their Solubilization Ability for Poorly Water-Soluble Drugs by Zhou, Zhengyuan, D’Emanuele, Antony, Lennon, Kieran, Attwood, David

“…A series of linear−dendritic copolymers were synthesized by conjugating BE block copolymers (B8E41 and B16E42, B = 1,2-butylene oxide and E = ethylene oxide)…”
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Worm-like micelles of triblock copolymer of ethylene oxide and styrene oxide characterised using light scattering and Taylor dispersion analysis by Zhou, Zhengyuan, Chhabria, Vikesh, D'Emanuele, Antony, Forbes, Robert T.

“…[Display omitted] A triblock ESE copolymer (E16S8E16, S = styrene oxide and E = ethylene oxide) was synthesised by sequential oxyanionic copolymerisation of…”
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