Search Results - "D’Avolio, Antonio"

Development and validation of a UHPLC-MS/MS method for quantification of the prodrug remdesivir and its metabolite GS-441524: a tool for clinical pharmacokinetics of SARS-CoV-2/COVID-19 and Ebola virus disease by Avataneo, Valeria, de Nicolò, Amedeo, Cusato, Jessica, Antonucci, Miriam, Manca, Alessandra, Palermiti, Alice, Waitt, Catriona, Walimbwa, Stephen, Lamorde, Mohammed, di Perri, Giovanni, D’Avolio, Antonio

“…Abstract Background Remdesivir has received significant attention for its potential application in the treatment of COVID-19, caused by SARS-CoV-2. Remdesivir…”
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LC-MS application for therapeutic drug monitoring in alternative matrices by Avataneo, Valeria, D’Avolio, Antonio, Cusato, Jessica, Cantù, Marco, De Nicolò, Amedeo

“…•Last five years literature about LC–MS has been checked for this review.•Newest technologies and devices have been deeply described and discussed.•The most…”
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Coronavirus disease 2019 and first-trimester spontaneous abortion: a case-control study of 225 pregnant patients by Cosma, Stefano, Carosso, Andrea R., Cusato, Jessica, Borella, Fulvio, Carosso, Marco, Bovetti, Marialuisa, Filippini, Claudia, D’Avolio, Antonio, Ghisetti, Valeria, Di Perri, Giovanni, Benedetto, Chiara

“…The disease caused by the severe acute respiratory syndrome coronavirus 2 was named coronavirus disease 2019 and classified as a global public health…”
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Mineralocorticoid Receptor Antagonist Effect on Aldosterone to Renin Ratio in Patients With Primary Aldosteronism by Pecori, Alessio, Buffolo, Fabrizio, Burrello, Jacopo, Mengozzi, Giulio, Rumbolo, Francesca, Avataneo, Valeria, D’Avolio, Antonio, Rabbia, Franco, Bertello, Chiara, Veglio, Franco, Mulatero, Paolo, Monticone, Silvia

“…Abstract Context Although current international guidelines recommend to avoid mineralocortcoid receptor antagonists in patients undergoing screening test for…”
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Pharmacokinetics and pharmacogenetics of high-dosage tedizolid for disseminated nocardiosis in a lung transplant patient by Corcione, Silvia, Vita, Davide, De Nicolò, Amedeo, Scabini, Silvia, Mornese Pinna, Simone, Cusato, Jessica, Mangiapia, Mauro, D'Avolio, Antonio, De Rosa, Francesco Giuseppe

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Efficacy and safety of a single switch from etanercept originator to etanercept biosimilar in a cohort of inflammatory arthritis by Ditto, Maria Chiara, Parisi, Simone, Priora, Marta, Sanna, Silvia, Peroni, Clara Lisa, Laganà, Angela, D’Avolio, Antonio, Fusaro, Enrico

“…AntiTNF-α biosimilars are broadly available for the treatment of inflammatory arthritis. There are a lot of data concerning the maintenance of clinical…”
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Development and validation of UHPLC–MS/MS methods for the quantification of colistin in plasma and dried plasma spots by Cangemi, Giuliana, Barco, Sebastiano, Castagnola, Elio, Tripodi, Gino, Favata, Fabio, D’Avolio, Antonio

“…[Display omitted] •A new method to quantify colistin A and B in dried plasma spots (DPS) is reported.•The method was compared to a standard method to quantify…”
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Comparative Performance Assessment of Novel Fluorescence Immunoassay POCTs for Measuring Circulating Levels of Vitamin-D by Palermiti, Alice, Manca, Alessandra, Mastrantonio, Fabrizio, Maiese, Domenico, Curatolo, Aurora, Antonucci, Miriam, Simiele, Marco, De Nicolò, Amedeo, D'Avolio, Antonio

“…Vitamin D (Vit D) is a fat-soluble molecule acting like a hormone, and it is involved in several biological mechanisms such as gene expression, calcium…”
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Pharmacokinetics and Safety of Twice-daily Ritonavir-boosted Atazanavir With Rifampicin by Gausi, Kamunkhwala, Mugerwa, Henry, Siccardi, Marco, Montanha, Maiara Camotti, Lamorde, Mohammed, Wiesner, Lubbe, D’Avolio, Antonio, McIlleron, Helen, Wilkins, Edmund, De Nicolò, Amedeo, Maartens, Gary, Khoo, Saye, Kityo, Cissy, Denti, Paolo, Waitt, Catriona

“…Abstract Background Critical drug-drug interactions (DDI) and hepatotoxicity complicate concurrent use of rifampicin and protease inhibitors. We investigated…”
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A 30-years review on pharmacokinetics of antibiotics: is the right time for pharmacogenetics? by Baietto, Lorena, Corcione, Silvia, Pacini, Giovanni, Perri, Giovanni Di, D'Avolio, Antonio, De Rosa, Francesco Giuseppe

“…Drug bioavailability may vary greatly amongst individuals, affecting both efficacy and toxicity: in humans, genetic variations account for a relevant…”
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A UHPLC–MS/MS method for the quantification of direct antiviral agents simeprevir, daclatasvir, ledipasvir, sofosbuvir/GS-331007, dasabuvir, ombitasvir and paritaprevir, together with ritonavir, in human plasma by Ariaudo, Alessandra, Favata, Fabio, De Nicolò, Amedeo, Simiele, Marco, Paglietti, Luca, Boglione, Lucio, Cardellino, Chiara Simona, Carcieri, Chiara, Di Perri, Giovanni, D’Avolio, Antonio

“…[Display omitted] •First UHPLC–MS/MS method to quantify all current anti-HCV direct acting antivirals.•Full validation according to FDA guidelines.•High…”
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Older Age is Associated with Higher Dolutegravir Exposure in Plasma and Cerebrospinal Fluid of People Living with HIV by Calcagno, Andrea, Moltó, José, Borghetti, Alberto, Gervasoni, Cristina, Milesi, Maurizio, Valle, Marta, Avataneo, Valeria, Alcantarini, Chiara, Pla-Junca, Francesc, Trunfio, Mattia, D’Avolio, Antonio, Di Giambenedetto, Simona, Cattaneo, Dario, Di Perri, Giovanni, Bonora, Stefano

“…Background People living with human immunodeficiency virus are ageing under combination antiretroviral treatments but data on drug exposure in serum and…”
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A simple high performance liquid chromatography–mass spectrometry method for Therapeutic Drug Monitoring of isavuconazole and four other antifungal drugs in human plasma samples by Fatiguso, Giovanna, Favata, Fabio, Zedda, Ilaria, De Nicolò, Amedeo, Cusato, Jessica, Avataneo, Valeria, Di Perri, Giovanni, D’Avolio, Antonio

“…Overlaid chromatograms showing the retention times of Fluconazole (FLU), Voriconazole (VRC), Posaconazole (PSC), Isavuconazole (ISC), Itraconazole (ITC) and…”
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Development and validation of a HPLC-UV method for the quantification of antiepileptic drugs in dried plasma spots by Baldelli, Sara, Cattaneo, Dario, Giodini, Luciana, Baietto, Lorena, Di Perri, Giovanni, D'Avolio, Antonio, Clementi, Emilio

“…Therapeutic drug monitoring (TDM) of antiepileptic drugs is widely used in clinical practice to optimise therapy, but it is limited by technical problems and…”
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The Effect of Rifampicin on Darunavir, Ritonavir, and Dolutegravir Exposure within Peripheral Blood Mononuclear Cells: a Dose Escalation Study by De Nicolò, Amedeo, Calcagno, Andrea, Motta, Ilaria, De Vivo, Elisa, D'Avolio, Antonio, Di Perri, Giovanni, Wiesner, Lubbe, Ebrahim, Isma-Eel, Maartens, Gary, Orrell, Catherine, McIlleron, Helen

“…Ritonavir-boosted darunavir (DRV/r) and dolutegravir (DTG) are affected by induction of metabolizing enzymes and efflux transporters caused by rifampicin…”
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Stability Study of Fosfomycin in Elastomeric Pumps at 4 °C and 34 °C: Technical Bases for a Continuous Infusion Use for Outpatient Parenteral Antibiotic Therapy by Manca, Alessandra, Palermiti, Alice, Mula, Jacopo, Cusato, Jessica, Maiese, Domenico, Simiele, Marco, De Nicolò, Amedeo, D’Avolio, Antonio

“…Background: Fosfomycin acts against aerobic Gram−/+ bacteria by blocking the synthesis of peptidoglycan. Its use has been currently re-evaluated for…”
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An open-label, randomized, single intravenous dosing study to investigate the effect of fixed-dose combinations of tenofovir/lamivudine or atazanavir/ritonavir on the pharmacokinetics of remdesivir in Ugandan healthy volunteers (RemTLAR) by Walimbwa, Stephen I, Kaboggoza, Julian P, Waitt, Catriona, Byakika-Kibwika, Pauline, D'Avolio, Antonio, Lamorde, Mohammed

“…Remdesivir is a novel broad-spectrum antiviral therapeutic with activity against several viruses that cause emerging infectious diseases. The purpose of this…”
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Possible Impact of Vitamin D Status and Supplementation on SARS-CoV-2 Infection Risk and COVID-19 Symptoms in a Cohort of Patients with Inflammatory Bowel Disease by De Nicolò, Amedeo, Cusato, Jessica, Bezzio, Cristina, Saibeni, Simone, Vernero, Marta, Disabato, Michela, Caviglia, Gian Paolo, Ianniello, Alice, Manca, Alessandra, D'Avolio, Antonio, Ribaldone, Davide Giuseppe

“…The coronavirus disease (COVID-19) pandemic represents a global health challenge, particularly considering concomitant diseases. Patients with inflammatory…”
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LC-MS/MS-Based Quantification of 9 Antiepileptic Drugs From a Dried Sample Spot Device by DʼUrso, Annachiara, Cangemi, Giuliana, Barco, Sebastiano, Striano, Pasquale, DʼAvolio, Antonio, de Grazia, Ugo

“…Therapeutic drug monitoring (TDM) of antiepileptic drugs (AEDs) is commonly performed on plasma or serum. The use of dried plasma spots (DPSs) could represent…”
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Lack of concordance between EMIT assay and LC-MS/MS for Therapeutic Drug Monitoring of Mycophenolic Acid: Potential increased risk for graft rejection? by De Nicolò, Amedeo, Ianniello, Alice, Benagli, Cinzia, Della Bruna, Roberto, Keller, Franco, Antonucci, Miriam, D’Avolio, Antonio, Cantù, Marco

“…[Display omitted] •Analysis of concordance between EMIT and LC–MS/MS for TDM of Mycophenolic Acid.•Accuracy of LC–MS/MS method was tested by proficiency and…”
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