Search Results - "D’Aurizio, Romina"

Recombinant human cytomegalovirus (HCMV) RL13 binds human immunoglobulin G Fc by Cortese, Mirko, Calò, Stefano, D'Aurizio, Romina, Lilja, Anders, Pacchiani, Nicola, Merola, Marcello

“…The human cytomegalovirus (HCMV) protein RL13 has recently been described to be present in all primary isolates but rapidly mutated in culture adapted viruses…”
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Nanopore sequencing data analysis: state of the art, applications and challenges by Magi, Alberto, Semeraro, Roberto, Mingrino, Alessandra, Giusti, Betti, D'Aurizio, Romina

“…Abstract The nanopore sequencing process is based on the transit of a DNA molecule through a nanoscopic pore, and since the 90s is considered as one of the…”
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The creation and selection of mutations resistant to a gene drive over multiple generations in the malaria mosquito by Hammond, Andrew M, Kyrou, Kyros, Bruttini, Marco, North, Ace, Galizi, Roberto, Karlsson, Xenia, Kranjc, Nace, Carpi, Francesco M, D'Aurizio, Romina, Crisanti, Andrea, Nolan, Tony

“…Gene drives have enormous potential for the control of insect populations of medical and agricultural relevance. By preferentially biasing their own…”
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Surfome Analysis as a Fast Track to Vaccine Discovery by Doro, Francesco, Liberatori, Sabrina, Rodríguez-Ortega, Manuel J., Rinaudo, Cira D., Rosini, Roberto, Mora, Marirosa, Scarselli, Maria, Altindis, Emrah, D'Aurizio, Romina, Stella, Maria, Margarit, Immaculada, Maione, Domenico, Telford, John L., Norais, Nathalie, Grandi, Guido

“…Safe recombinant vaccines, based on a small number of antigenic proteins, are emerging as the most attractive, cost-effective solution against infectious…”
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A Census of Tandemly Repeated Polymorphic Loci in Genic Regions Through the Comparative Integration of Human Genome Assemblies by Genovese, Loredana M, Geraci, Filippo, Corrado, Lucia, Mangano, Eleonora, D'Aurizio, Romina, Bordoni, Roberta, Severgnini, Marco, Manzini, Giovanni, De Bellis, Gianluca, D'Alfonso, Sandra, Pellegrini, Marco

“…Polymorphic Tandem Repeat (PTR) is a common form of polymorphism in the human genome. A PTR consists in a variation found in an individual (or in a population)…”
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Detection of Genomic Structural Variants from Next-Generation Sequencing Data by Tattini, Lorenzo, D'Aurizio, Romina, Magi, Alberto

“…Structural variants are genomic rearrangements larger than 50 bp accounting for around 1% of the variation among human genomes. They impact on phenotypic…”
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Altered Metabolic Profile and Adipocyte Insulin Resistance Mark Severe Liver Fibrosis in Patients with Chronic Liver Disease by Gaggini, Melania, Carli, Fabrizia, Rosso, Chiara, Younes, Ramy, D'Aurizio, Romina, Bugianesi, Elisabetta, Gastaldelli, Amalia

“…Metabolomics/lipidomics are important tools to identify novel biomarkers associated with liver damage. Patients with chronic liver disease (CLD) and hepatitis…”
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MicroRNA Expression in the Aqueous Humor of Patients with Diabetic Macular Edema by Grieco, Giuseppina Emanuela, Sebastiani, Guido, Eandi, Chiara Maria, Neri, Giovanni, Nigi, Laura, Brusco, Noemi, D'Aurizio, Romina, Posarelli, Matteo, Bacci, Tommaso, Benedetto, Elena De, Fruschelli, Mario, Orlandini, Maurizio, Galvagni, Federico, Dotta, Francesco, Tosi, Gian Marco

“…We identified and compared secreted microRNA (miRNA) expression in aqueous humor (AH) and plasma samples among patients with: type 2 diabetes mellitus (T2D)…”
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Integrative analysis of differentially expressed genes and miRNAs predicts complex T3-mediated protective circuits in a rat model of cardiac ischemia reperfusion by Forini, Francesca, Nicolini, Giuseppina, Kusmic, Claudia, D’Aurizio, Romina, Rizzo, Milena, Baumgart, Mario, Groth, Marco, Doccini, Stefano, Iervasi, Giorgio, Pitto, Letizia

“…Thyroid hormone (T3) dyshomeostasis in the cardiac ischemia-reperfusion (IR) setting negatively impacts on mitochondria function and extracellular matrix…”
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Bridging between Mouse and Human Enhancer-Promoter Long-Range Interactions in Neural Stem Cells, to Understand Enhancer Function in Neurodevelopmental Disease by D’Aurizio, Romina, Catona, Orazio, Pitasi, Mattia, Li, Yang Eric, Ren, Bing, Nicolis, Silvia Kirsten

“…Non-coding variation in complex human disease has been well established by genome-wide association studies, and is thought to involve regulatory elements, such…”
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NRF2 activation by cysteine as a survival mechanism for triple-negative breast cancer cells by Bottoni, Laura, Minetti, Alberto, Realini, Giulia, Pio, Elena, Giustarini, Daniela, Rossi, Ranieri, Rocchio, Chiara, Franci, Lorenzo, Salvini, Laura, Catona, Orazio, D’Aurizio, Romina, Rasa, Mahdi, Giurisato, Emanuele, Neri, Francesco, Orlandini, Maurizio, Chiariello, Mario, Galvagni, Federico

“…Triple-negative breast cancer (TNBC) is a very aggressive and heterogeneous group of tumors. In order to develop effective therapeutic strategies, it is…”
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miR-182-5p is an evolutionarily conserved Tbx5 effector that impacts cardiac development and electrical activity in zebrafish by Guzzolino, Elena, Pellegrino, Mario, Ahuja, Neha, Garrity, Deborah, D’Aurizio, Romina, Groth, Marco, Baumgart, Mario, Hatcher, Cathy J., Mercatanti, Alberto, Evangelista, Monica, Ippolito, Chiara, Tognoni, Elisabetta, Fukuda, Ryuichi, Lionetti, Vincenzo, Pellegrini, Marco, Cremisi, Federico, Pitto, Letizia

“…To dissect the TBX5 regulatory circuit, we focused on microRNAs (miRNAs) that collectively contribute to make TBX5 a pivotal cardiac regulator. We profiled…”
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High-Throughput Identification of miRNA-Target Interactions in Melanoma Using miR-CATCHv2.0 by Marranci, Andrea, D'Aurizio, Romina, Rizzo, Milena, Greene, Catherine M, Poliseno, Laura

“…MicroRNAs (miRNAs) can regulate the expression of potentially every transcript in the cell, and the definition of miRNA-target interactions is crucial to…”
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Slowly progressive autosomal dominant Alport Syndrome due to COL4A3 splicing variant by Daga, Sergio, Loberti, Lorenzo, Rollo, Giulia, Adamo, Loredaria, Colavecchio, Olga Lorenza, Brunelli, Giulia, Zguro, Kristina, Tripodi, Sergio Antonio, Guarnieri, Andrea, Garosi, Guido, D'Aurizio, Romina, Ariani, Francesca, Tita, Rossella, Renieri, Alessandra, Pinto, Anna Maria

“…Alport syndrome is a rare genetic kidney disease caused by variants in the COL4A3/A4/A5 genes. It's characterised by progressive kidney failure, though…”
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Hooked Up from a Distance: Charting Genome-Wide Long-Range Interaction Maps in Neural Cells Chromatin to Identify Novel Candidate Genes for Neurodevelopmental Disorders by Mercurio, Sara, Pozzolini, Giorgia, Baldi, Roberta, Barilà, Sara E, Pitasi, Mattia, Catona, Orazio, D'Aurizio, Romina, Nicolis, Silvia K

“…DNA sequence variants (single nucleotide polymorphisms or variants, SNPs/SNVs; copy number variants, CNVs) associated to neurodevelopmental disorders (NDD) and…”
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Artificial Intelligence Predictive Models of Response to Cytotoxic Chemotherapy Alone or Combined to Targeted Therapy for Metastatic Colorectal Cancer Patients: A Systematic Review and Meta-Analysis by Russo, Valentina, Lallo, Eleonora, Munnia, Armelle, Spedicato, Miriana, Messerini, Luca, D’Aurizio, Romina, Ceroni, Elia Giuseppe, Brunelli, Giulia, Galvano, Antonio, Russo, Antonio, Landini, Ida, Nobili, Stefania, Ceppi, Marcello, Bruzzone, Marco, Cianchi, Fabio, Staderini, Fabio, Roselli, Mario, Riondino, Silvia, Ferroni, Patrizia, Guadagni, Fiorella, Mini, Enrico, Peluso, Marco

“…Tailored treatments for metastatic colorectal cancer (mCRC) have not yet completely evolved due to the variety in response to drugs. Therefore, artificial…”
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The FHP01 DDX3X Helicase Inhibitor Exerts Potent Anti-Tumor Activity In Vivo in Breast Cancer Pre-Clinical Models by Gherardini, Lisa, Inzalaco, Giovanni, Imperatore, Francesco, D’Aurizio, Romina, Franci, Lorenzo, Miragliotta, Vincenzo, Boccuto, Adele, Calandro, Pierpaolo, Andreini, Matteo, Tarditi, Alessia, Chiariello, Mario

“…Inhibition of DDX3X expression or activity reduces proliferation in cells from various tumor tissues, in particular in breast cancer, and its expression often…”
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Heterozygosity for neuronal ceroid lipofuscinosis predisposes to bipolar disorder by Privitera, Flavia, Trusso, Maria A, Valentino, Floriana, Doddato, Gabriella, Fallerini, Chiara, Brunelli, Giulia, D'Aurizio, Romina, Furini, Simone, Goracci, Arianna, Fagiolini, Andrea, Mari, Francesca, Renieri, Alessandra, Ariani, Francesca

“…Bipolar disorder is a heritable chronic mental disorder that causes psychosocial impairment through depressive/manic episodes. Familial transmission of bipolar…”
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Variations of circulating miRNA in paediatric patients with Heart Failure supported with Ventricular Assist Device: a pilot study by Ragusa, Rosetta, Di Molfetta, Arianna, D’Aurizio, Romina, Del Turco, Serena, Cabiati, Manuela, Del Ry, Silvia, Basta, Giuseppina, Pitto, Letizia, Amodeo, Antonio, Trivella, Maria Giovanna, Rizzo, Milena, Caselli, Chiara

“…Circulating miRNAs (c-miRNAs) are promising biomarkers for HF diagnosis and prognosis. There are no studies on HF pediatric patients undergoing…”
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The miR-28-5p Targetome Discovery Identified SREBF2 as One of the Mediators of the miR-28-5p Tumor Suppressor Activity in Prostate Cancer Cells by Fazio, Sofia, Berti, Gabriele, Russo, Francesco, Evangelista, Monica, D'Aurizio, Romina, Mercatanti, Alberto, Pellegrini, Marco, Rizzo, Milena

“…miR-28-5p is downregulated in some tumor tissues in which it has been demonstrated to have tumor suppressor (TS) activity. Here, we demonstrate that miR-28-5p…”
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