Search Results - "D’Atri, Domenico"
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Cell-specific cargo delivery using synthetic bacterial spores
Published in Cell reports (Cambridge) (31-01-2023)“…Delivery of cancer therapeutics to non-specific sites decreases treatment efficacy while increasing toxicity. In ovarian cancer, overexpression of the cell…”
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PLGA Nanoparticles Grafted with Hyaluronic Acid to Improve Site-Specificity and Drug Dose Delivery in Osteoarthritis Nanotherapy
Published in Nanomaterials (Basel, Switzerland) (30-06-2022)“…Nanoparticles (NPs) have a tremendous potential in medicinal applications, and recent studies have pushed the boundaries in nanotherapy, including in…”
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Nano-ghosts: Novel biomimetic nano-vesicles for the delivery of antisense oligonucleotides
Published in Journal of controlled release (10-05-2021)“…Antisense oligonucleotides (ASOs) carry an enormous therapeutic potential in different research areas, however, the lack of appropriate carriers for their…”
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Drug delivery in intervertebral disc degeneration and osteoarthritis: Selecting the optimal platform for the delivery of disease-modifying agents
Published in Journal of controlled release (10-12-2020)“…Osteoarthritis (OA) and intervertebral disc degeneration (IVDD) as major cause of chronic low back pain represent the most common degenerative joint…”
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Nano-Ghosts: Biomimetic membranal vesicles, technology and characterization
Published in Methods (San Diego, Calif.) (01-05-2020)“…•Investigation of Nano-Ghosts manufacturing-process robustness.•Examination of post-production shelf-life through stability and storage studies.•Demonstration…”
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Abstract 1739: Cell-specific cargo delivery using synthetic bacterial spores
Published in Cancer research (Chicago, Ill.) (15-06-2022)“…Abstract The overexpression of the cell surface receptor “HER-2” is a common marker for many breast and ovarian cancers. New treatments for these cancers…”
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Pretreating Mesenchymal Stem Cells with Cancer Conditioned‐Media or Proinflammatory Cytokines Changes the Tumor and Immune Targeting by Nanoghosts Derived from these Cells
Published in Advanced healthcare materials (01-05-2019)“…Nanoghosts (NGs) are nanovesicles reconstructed from the cytoplasmic membranes of mesenchymal stem cells (MSCs). By retaining MSC membranes, the NGs retain the…”
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Anti-HER2 cell specific doxorubicin delivery using synthetic bacterial spores for resistant ovarian cancer treatment
Published in The Journal of immunology (1950) (01-05-2023)“…Abstract Delivery of cancer therapeutics to non-specific sites decreases treatment efficacy while increasing toxicity. In ovarian cancer, overexpression of the…”
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