Search Results - "D’Angelo, Marina"

Assaying endogenous matrix metalloproteinases (MMPs) in acid-etched dentinal cavity walls by Justin KANG, Naomi IZUTANI, Marina D'ANGELO, William BUIS, Yu WANG, Markus BLATZ, Satoshi IMAZATO, Fusun OZER

“…Endogenous dentinal matrix metalloproteinases (MMPs) have been implicated in the auto-degradation of collagen fibrils within resin infiltrated layers of…”
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Joint and bone disease in mucopolysaccharidoses VI and VII : Identification of new therapeutic targets and biomarkers using animal models by SIMONARO, Calogera M, D'ANGELO, Marina, HASKINS, Mark E, SCHUCHMAN, Edward H

“…The mucopolysaccharidoses (MPS) are inherited metabolic disorders resulting from the defective catabolism of glycosaminoglycans. In this report, we find that…”
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Radiographic evaluation of bones and joints in mucopolysaccharidosis I and VII dogs after neonatal gene therapy by Herati, Ramin Sedaghat, Knox, Van W., O’Donnell, Patricia, D’Angelo, Marina, Haskins, Mark E., Ponder, Katherine P.

“…Mucopolysaccharidosis I (MPS I) and MPS VII are due to deficient activity of the glycosaminoglycan-degrading lysosomal enzymes α- l-iduronidase and…”
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F-spondin regulates chondrocyte terminal differentiation and endochondral bone formation by Palmer, Glyn D., Piton, Alejandro H., Thant, Lwin Mon, Oliveira, Serafim M., D'Angelo, Marina, Attur, Mukundan G., Abramson, Steven B., Teixeira, Cristina C.

“…This study examines the role of F‐spondin, an extracellular matrix protein of osteoarthritic cartilage, during chondrocyte maturation in embryonic growth plate…”
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The Osteopetrotic Mutation Toothless (tl) Is a Loss-of-Function Frameshift Mutation in the Rat Csf1 Gene: Evidence of a Crucial Role for CSF-1 in Osteoclastogenesis and Endochondral Ossification by Van Wesenbeeck, Liesbeth, Odgren, Paul R., MacKay, Carole A., D'Angelo, Marina, Safadi, Fayez F., Popoff, Steven N., Van Hul, Wim, Marks, Sandy C.

“…The toothless (tl) mutation in the rat is a naturally occurring, autosomal recessive mutation resulting in a profound deficiency of bone-resorbing osteoclasts…”
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Assaying endogenous matrix metalloproteinases (MMPs) in acid-etched dentinal cavity walls by KANG, Justin, IZUTANI, Naomi, D’ANGELO, Marina, BUIS, William, WANG, Yu, BLATZ, Markus, IMAZATO, Satoshi, OZER, Fusun

“…Endogenous dentinal matrix metalloproteinases (MMPs) have been implicated in the auto-degradation of collagen fibrils within resin infiltrated layers of…”
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Providing a Meaningful Virtual Research Laboratory Experience for Osteopathic Medical Students by D'Angelo, Marina, Hammond, Christine, Mattioli, Patrisia

“…Modern medical education embraces the education of the student beyond patient‐centered preparations, instilling the ability to assess and evaluate many…”
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Mechanism of Glycosaminoglycan-Mediated Bone and Joint Disease: Implications for the Mucopolysaccharidoses and Other Connective Tissue Diseases by Simonaro, Calogera M, D'Angelo, Marina, He, Xingxuan, Eliyahu, Efrat, Shtraizent, Nataly, Haskins, Mark E, Schuchman, Edward H

“…We have previously shown that glycosaminoglycan (GAG) storage in animal models of the mucopolysaccharidoses (MPS) leads to inflammation and apoptosis within…”
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Mechanism of Glycosaminoglycan-Mediated Bone and Joint Disease by Simonaro, Calogera M, D'Angelo, Marina, He, Xingxuan, Eliyahu, Efrat, Shtraizent, Nataly, Haskins, Mark E, Schuchman, Edward H

“…We have previously shown that glycosaminoglycan (GAG) storage in animal models of the mucopolysaccharidoses (MPS) leads to inflammation and apoptosis within…”
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Measuring clinically relevant endpoints in a serum-free, three-dimensional, primary cell culture system of human osteoarthritic articular chondrocytes by Bundens, Grace, Buckley, Andrea, Milton, LaBraya, Behling, Kathryn, Chmielewski, Sarah, Cho, Ellen, Lozano-Torres, Xiomara, Selim, Abdulhafez, Lackman, Richard, George-Weinstein, Mindy, Miller, Lawrence, D’Angelo, Marina

“…Osteoarthritis (OA) is characterized by degeneration of articular cartilage within the joint, inflammation and pain. The purpose of this study was to develop a…”
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Using A Community of Inquiry in the Design of Histology Curriculum for First Year Medical Students by McIntosh, Leslie P., Koch, Douglas, Claeson, Kerin, D'Angelo, Marina

“…Histology faculty in the Doctor of Osteopathy (DO) program at the Philadelphia College of Osteopathic Medicine revised the delivery methodology of first‐year…”
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Chronic Obstructive Pulmonary Diseased Human Lung Fibroblasts Secrete Increased Matrix Metalloproteases ‐12 and ‐8 by Mattioli, Patrisia, Koleoso, Olufela, Otto, Ashley, Saini, Twinkle, Shind, Christine, Baus, Emily, Bhatt, Amy, D'Angelo, Marina

“…According to the American Lung Association, 16.5 million people have Chronic Obstructive Pulmonary Disease (COPD), the third leading cause of death in the…”
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Gelatinase activity in synovial fluid and synovium obtained from healthy and osteoarthritic joints of dogs by Volk, S.W, Kapatkin, A.S, Haskins, M.E, Walton, R.M, D'Angelo, M

“…To determine matrix metalloproteinase (MMP) activity in synovial fluid (SF) obtained from the joints of dogs with degenerative joint disease (DJD) secondary to…”
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Extracellular Matrix Protection Factor Increases Sulfated Proteoglycan Production in Serum‐free, Primary Cultures of Human Osteoarthritic Chondrocytes by Morris, Gregory, Milton, LaBraya, Popper, Hannah, Buckley, Andrea, Mattioli, Patrisia, Behling, Kathryn, Selim, Abdulhafez, D'Angelo, Marina

“…Osteoarthritis (OA) is a common chronic condition which involves the loss of articular cartilage, the cushion between joints that provides a smooth surface for…”
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Authentic Matrix Vesicles Contain Active Metalloproteases (MMP) by D'Angelo, Marina, Billings, Paul C., Pacifici, Maurizio, Leboy, Phoebe S., Kirsch, Thorsten

“…Matrix vesicles (MV) play a key role in the initiation of cartilage mineralization. Although many components in these microstructures have been identified, the…”
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Extracellular Matrix Protection Factor‐1, a Novel Osteoarthritis Therapeutic, Decreases Expression of Interleukin‐1 beta by Primary Cultures of Human Osteoarthritic Chondrocytes by Belogorodsky, Dimitry, Buckley, Andrea Lynn, Milton, LaBraya, Popper, Hannah Ruth, Mattioli, Patrisia, Miller, Lawrence, Behling, Kathryn, Selim, Abdulhafez, D'Angelo, Marina

“…Osteoarthritis (OA) is characterized by an imbalance of cartilage extracellular matrix (ECM) production and degradation, due, in part, to increased cytokine…”
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Serum‐free Culture of Primary Human Gingival Fibroblasts Demonstrates Differences in Collagen Production Between Smokers and Non‐smokers: A System to Measure Effects of Novel Collagenase Inhibitors by Mattioli, Patrisia, Gambardella, Eric, Buckley, Andrea, Ruggieri, Natalino, Seutter, Sara, Green, Kevan, Selim, Abdulhafez, Borghaei, Ruth, D'Angelo, Marina

“…Abstract only Periodontal disease occurs in 50% of the world's population over the age of 30. It is an infectious and inflammatory disease that if left…”
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Serum‐free Cultures of Primary Equine Articular Chondrocytes Demonstrate Differences in Collagen Production And Degradation in Response to Extracellular Matrix Protection Factor (ECPF‐1), A Novel Osteoarthritis Therapeutic by Buckley, Andrea, Gambardella, Eric, Ruggieri, Natalino, Whiteman, Daniel, Goswami, Soumendro, Osadebe, Otitodilichukwu, Mattioli, Patrisia, Gilbertie, Jessica, Selim, Abdulhafez, D'Angelo, Marina

“…Abstract only Reproducible, long term culture of primary, articular chondrocytes has been difficult regardless of mammalian species of origin because articular…”
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Optimizing a Novel, Serum‐Free, Three‐Dimensional Culture System of Primary Human Osteoarthritic Chondrocytes: A Clinically Relevant Platform to Test and Develop Osteoarthritis Therapeutics by Popper, Hannah Ruth, Buckley, Andrea Lynn, Mattioli, Patrisia, Milton, LaBraya, Alsaid, Firas, Miller, Lawrence, Kim, Tae‐Won, Pollard, Mark, Behling, Kathryn, Selim, Abdulhafez, D'Angelo, Marina

“…Osteoarthritis (OA), a progressive and degenerative disease, affects millions of aging adults and results in the loss of cartilage. In healthy joints,…”
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Extracellular Matrix Protection Factor‐2 Reduces Collagen Degradation in Primary Serum‐Free Cultures of Inflamed Human Gingival Fibroblasts by Chmielewski, Sarah, Mattioli, Patrisia, Isaac, Tamika, Buckley, Andrea Lynn, Seutter, Sara, Gambardella, Eric, Green, Kevan, Shamseddin, Seyed, Borghaei, Ruth, Selim, Abdulhafez, D'Angelo, Marina

“…Some form of periodontal disease affects nearly everyone over the age of 30. The hallmarks of periodontal disease include inflammation of the gum tissue…”
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