Search Results - "D’Alfonso, R."

Molecular analysis based on mtLSU-rRNA and DHPS sequences of Pneumocystis jirovecii from immunocompromised and immunocompetent patients in Italy by Dimonte, S., Berrilli, F., D’Orazi, C., D’Alfonso, R., Placco, F., Bordi, E., Perno, C.F., Di Cave, D.

“…• We analyze the rate mutations of Pneumocystis at mtLSU and DHPS loci. • No differences in mtLSU genotypes frequences among the different types of patients…”
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Intratumoral Delivery of Immunotherapy-Act Locally, Think Globally by Aznar, M Angela, Tinari, Nicola, Rullán, Antonio J, Sánchez-Paulete, Alfonso R, Rodriguez-Ruiz, María E, Melero, Ignacio

“…Immune mechanisms have evolved to cope with local entry of microbes acting in a confined fashion but eventually inducing systemic immune memory. Indeed, in…”
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Social determinants associated with Giardia duodenalis infection in southern Côte d’Ivoire by Berrilli, F., Di Cave, D., N’Guessan, R., Kaboré, Y., Giangaspero, A., Sorge, R. P., D’Alfonso, R.

“…The purpose of this investigation was to analyze the association between different social determinants of health at the local scale and Giardia duodenalis…”
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COVID-19 Pathogenesis and Clinical Manifestations by Hernandez Acosta, R. Alfonso, Esquer Garrigos, Zerelda, Marcelin, Jasmine R., Vijayvargiya, Prakhar

“…In this review, we summarize the current knowledge about the virology, the host-pathogen interactions and pathogenesis of coronavirus disease 2019 in humans…”
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Cancer Immunotherapy with Immunomodulatory Anti-CD137 and Anti-PD-1 Monoclonal Antibodies Requires BATF3-Dependent Dendritic Cells by Sánchez-Paulete, Alfonso R, Cueto, Francisco J, Martínez-López, María, Labiano, Sara, Morales-Kastresana, Aizea, Rodríguez-Ruiz, María E, Jure-Kunkel, Maria, Azpilikueta, Arantza, Aznar, M Angela, Quetglas, José I, Sancho, David, Melero, Ignacio

“…Weak and ineffective antitumor cytotoxic T lymphocyte (CTL) responses can be rescued by immunomodulatory mAbs targeting PD-1 or CD137. Using Batf3(-/-) mice,…”
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Intratumor Adoptive Transfer of IL-12 mRNA Transiently Engineered Antitumor CD8+ T Cells by Etxeberria, Iñaki, Bolaños, Elixabet, Quetglas, Jose I., Gros, Alena, Villanueva, Alberto, Palomero, Jara, Sánchez-Paulete, Alfonso R., Piulats, Jose María, Matias-Guiu, Xavier, Olivera, Irene, Ochoa, Maria C., Labiano, Sara, Garasa, Saray, Rodriguez, Inmaculada, Vidal, August, Mancheño, Uxua, Hervás-Stubbs, Sandra, Azpilikueta, Arantza, Otano, Itziar, Aznar, M. Angela, Sanmamed, Miguel F., Inogés, Susana, Berraondo, Pedro, Teijeira, Álvaro, Melero, Ignacio

“…Retroviral gene transfer of interleukin-12 (IL-12) into T cells markedly enhances antitumor efficacy upon adoptive transfer but has clinically shown…”
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Probing left-handed heavy neutral leptons in the Vector Scotogenic Model by Paulo Areyuna, C., Zamora-Saa, Jilberto, Zerwekh, Alfonso R.

“…A bstract In this work, we consider an extension to the Standard Model composed by a Massive Vector Doublet under SU(2) L and a Left-handed Heavy Neutral…”
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Navigating Democracy’s Fragile Boundary: Lessons from Plato on Political Leadership by Vergaray, Alfonso R.

“…This article presents a case that former President of the United States Donald Trump was a tyrant-like leader in the mold of the tyrant in Plato’s Republic…”
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Deciphering CD137 (4‐1BB) signaling in T‐cell costimulation for translation into successful cancer immunotherapy by Sanchez‐Paulete, Alfonso R., Labiano, Sara, Rodriguez‐Ruiz, Maria E., Azpilikueta, Arantza, Etxeberria, Iñaki, Bolaños, Elixabet, Lang, Valérie, Rodriguez, Manuel, Aznar, M. Angela, Jure‐Kunkel, Maria, Melero, Ignacio

“…CD137 (4‐1BB, TNF‐receptor superfamily 9) is a surface glycoprotein of the TNFR family which can be induced on a variety of leukocyte subsets. On T and NK…”
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Prevalence of chronic endometritis in repeated unexplained implantation failure and the IVF success rate after antibiotic therapy by Cicinelli, Ettore, Matteo, Maria, Tinelli, Raffaele, Lepera, Achiropita, Alfonso, Raffaello, Indraccolo, Ugo, Marrocchella, Sonia, Greco, Pantaleo, Resta, Leonardo

“…STUDY QUESTION What is the prevalence of chronic endometritis (CE) in women with repeated unexplained implantation failure (RIF) at IVF, and how does…”
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Intratumoral Immunotherapy with XCL1 and sFlt3L Encoded in Recombinant Semliki Forest Virus-Derived Vectors Fosters Dendritic Cell-Mediated T-cell Cross-Priming by Sánchez-Paulete, Alfonso R, Teijeira, Álvaro, Quetglas, José I, Rodríguez-Ruiz, María E, Sánchez-Arráez, Álvaro, Labiano, Sara, Etxeberria, Iñaki, Azpilikueta, Arantza, Bolaños, Elixabet, Ballesteros-Briones, María Cristina, Casares, Noelia, Quezada, Sergio A, Berraondo, Pedro, Sancho, David, Smerdou, Cristian, Melero, Ignacio

“…: Multiple lines of evidence indicate a critical role of antigen cross-presentation by conventional BATF3-dependent type 1 classical dendritic cells (cDC1) in…”
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Contaminated land in Colombia: A critical review of current status and future approach for the management of contaminated sites by Arias Espana, Victor Andres, Rodriguez Pinilla, Alfonso R., Bardos, Paul, Naidu, Ravi

“…Environmental contaminants can have negative effects on human health and land, air and water resources. Consequently, there have been significant advances in…”
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Repurposing the yellow fever vaccine for intratumoral immunotherapy by Aznar, Maria Angela, Molina, Carmen, Teijeira, Alvaro, Rodriguez, Inmaculada, Azpilikueta, Arantza, Garasa, Saray, Sanchez‐Paulete, Alfonso R, Cordeiro, Luna, Etxeberria, Iñaki, Alvarez, Maite, Rius‐Rocabert, Sergio, Nistal‐Villan, Estanislao, Berraondo, Pedro, Melero, Ignacio

“…Live 17D is widely used as a prophylactic vaccine strain for yellow fever virus that induces potent neutralizing humoral and cellular immunity against the…”
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Targeting Macrophages with CAR T Cells Delays Solid Tumor Progression and Enhances Antitumor Immunity by Sánchez-Paulete, Alfonso R, Mateus-Tique, Jaime, Mollaoglu, Gurkan, Nielsen, Sebastian R, Marks, Adam, Lakshmi, Ashwitha, Khan, Jalal A, Wilk, C Matthias, Pia, Luisanna, Baccarini, Alessia, Merad, Miriam, Brown, Brian D

“…Tumor-associated macrophages (TAM) are one of the most abundant cell types in many solid tumors and typically exert protumor effects. This has led to an…”
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Mitochondrial Morphological and Functional Reprogramming Following CD137 (4-1BB) Costimulation by Teijeira, Alvaro, Labiano, Sara, Garasa, Saray, Etxeberria, Iñaki, Santamaría, Eva, Rouzaut, Ana, Enamorado, Michel, Azpilikueta, Arantza, Inoges, Susana, Bolaños, Elixabet, Aznar, Maria Angela, Sánchez-Paulete, Alfonso R, Sancho, David, Melero, Ignacio

“…T and NK lymphocytes express CD137 (4-1BB), a costimulatory receptor of the TNFR family whose function is exploitable for cancer immunotherapy. Mitochondria…”
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Abscopal Effects of Radiotherapy Are Enhanced by Combined Immunostimulatory mAbs and Are Dependent on CD8 T Cells and Crosspriming by Rodriguez-Ruiz, María E, Rodriguez, Inmaculada, Garasa, Saray, Barbes, Benigno, Solorzano, Jose Luis, Perez-Gracia, Jose Luis, Labiano, Sara, Sanmamed, Miguel F, Azpilikueta, Arantza, Bolaños, Elixabet, Sanchez-Paulete, Alfonso R, Aznar, M Angela, Rouzaut, Ana, Schalper, Kurt A, Jure-Kunkel, Maria, Melero, Ignacio

“…Preclinical and clinical evidence indicate that the proimmune effects of radiotherapy can be synergistically augmented with immunostimulatory mAbs to act both…”
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A new formalism for reference dosimetry of small and nonstandard fields by Alfonso, R., Andreo, P., Capote, R., Huq, M. Saiful, Kilby, W., Kjäll, P., Mackie, T. R., Palmans, H., Rosser, K., Seuntjens, J., Ullrich, W., Vatnitsky, S.

“…The use of small fields in radiotherapy techniques has increased substantially, in particular in stereotactic treatments and large uniform or nonuniform fields…”
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Computational Investigation of FeS2 Surfaces and Prediction of Effects of Sulfur Environment on Stabilities by Alfonso, Dominic R

“…Density functional theory calculations were employed to investigate the (001), (210), (111), and (110) surfaces of FeS2. The surface free energies were…”
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Predicted Chance That Global Warming Will Temporarily Exceed 1.5 °C by Smith, D. M., Scaife, A. A., Hawkins, E., Bilbao, R., Boer, G. J., Caian, M., Caron, L.‐P., Danabasoglu, G., Delworth, T., Doblas‐Reyes, F. J., Doescher, R., Dunstone, N. J., Eade, R., Hermanson, L., Ishii, M., Kharin, V., Kimoto, M., Koenigk, T., Kushnir, Y., Matei, D., Meehl, G. A., Menegoz, M., Merryfield, W. J., Mochizuki, T., Müller, W. A., Pohlmann, H., Power, S., Rixen, M., Sospedra‐Alfonso, R., Tuma, M., Wyser, K., Yang, X., Yeager, S.

“…The Paris Agreement calls for efforts to limit anthropogenic global warming to less than 1.5 °C above preindustrial levels. However, natural internal…”
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The axigluon, a four-site model and the top quark forward–backward asymmetry at the Tevatron by Zerwekh, Alfonso R.

“…Very recently, it has been shown by other authors that the CDF measurement of the top quark forward–backward asymmetry can be explained by means of a heavy and…”
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