Search Results - "DʼIncalci, Maurizio"

Immediate Cooling Does Not Prevent the Ex Vivo Hydrolysis of L-Asparagine by Asparaginase by LANVERS-KAMINSKY, Claudia, WESTHOFF, Petra Schulze, D'INCALCI, Maurizio, ZUCCHETTI, Massimo, BOOS, Joachim

“…Monitoring of asparagine (ASN) during asparaginase (ASE) treatment directly links to the antileukemic effect of ASE but is challenging because of ASE-induced…”
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Trabectedin therapy for sarcomas by Casali, Paolo G, Sanfilippo, Roberta, DʼIncalci, Maurizio

“…PURPOSE OF REVIEWThe therapeutic armamentarium of adult soft-tissue sarcomas (STS) has widened in recent years. This was also due to increased consideration of…”
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Cisplatinum and Taxol Induce Different Patterns of p53 Phosphorylation by Damia, Giovanna, Filiberti, Laura, Vikhanskaya, Faina, Carrassa, Laura, Taya, Yoichi, Dincalci, Maurizio, Broggini, Massimo

“…Posttranslational modifications of p53 induced by two widely used anticancer agents, cisplatinum (DDP) and taxol were investigated in two human cancer cell…”
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Inactivation of DNA repair triggers neoantigen generation and impairs tumour growth by Germano, Giovanni, Lamba, Simona, Rospo, Giuseppe, Barault, Ludovic, Magrì, Alessandro, Maione, Federica, Russo, Mariangela, Crisafulli, Giovanni, Bartolini, Alice, Lerda, Giulia, Siravegna, Giulia, Mussolin, Benedetta, Frapolli, Roberta, Montone, Monica, Morano, Federica, de Braud, Filippo, Amirouchene-Angelozzi, Nabil, Marsoni, Silvia, D’Incalci, Maurizio, Orlandi, Armando, Giraudo, Enrico, Sartore-Bianchi, Andrea, Siena, Salvatore, Pietrantonio, Filippo, Di Nicolantonio, Federica, Bardelli, Alberto

“…The inactivation of DNA mismatch repair in cancer cells produces dynamic mutational profiles and generates neoantigens, which result in improved immune…”
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Trabectedin for the treatment of breast cancer by D'Incalci, Maurizio, Zambelli, Alberto

“…Trabectedin is an anti-tumor compound registered in Europe and in several other countries, for the second-line treatment of soft tissue sarcoma (STS) and for…”
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PEGylated Nanoparticles Obtained through Emulsion Polymerization as Paclitaxel Carriers by Colombo, Claudio, Morosi, Lavinia, Bello, Ezia, Ferrari, Raffaele, Licandro, Simonetta Andrea, Lupi, Monica, Ubezio, Paolo, Morbidelli, Massimo, Zucchetti, Massimo, D’Incalci, Maurizio, Moscatelli, Davide, Frapolli, Roberta

“…Polymer nanoparticles (NPs) represent a promising way to deliver poorly water-soluble anticancer drugs without the use of unwanted excipients, whose presence…”
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Combination of trabectedin and irinotecan is highly effective in a human rhabdomyosarcoma xenograft by Riccardi, Anna, Meco, Daniela, Ubezio, Paolo, Mazzarella, Giorgio, Marabese, Mirko, Faircloth, Glynn T, Jimeno, José, DʼIncalci, Maurizio, Riccardi, Riccardo

“…Our objective was to evaluate in vitro and in vivo the effect of the combination of trabectedin (Yondelis, ET-743) and irinotecan (CPT-11) or its major…”
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Abstract 1284: Lurbinectedin reduces tumor-associated macrophages and the production of inflammatory cytokines, chemokines, and angiogenic factors in preclinical models by Allavena, Paola, Belgiovine, Cristina, Liguori, Manuela, Bello, Ezia, Frapolli, Roberta, Galmarini, Carlos M., D’Incalci, Maurizio

“…Abstract Lurbinectedin, currently undergoing clinical evaluation in ovarian, breast and small-cell lung cancer patients, inhibits active transcription. The…”
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MAL gene overexpression as a marker of high-grade serous ovarian carcinoma stem-like cells that predicts chemoresistance and poor prognosis by Zanotti, Laura, Romani, Chiara, Tassone, Laura, Todeschini, Paola, Tassi, Renata Alessandra, Bandiera, Elisabetta, Damia, Giovanna, Ricci, Francesca, Ardighieri, Laura, Calza, Stefano, Marchini, Sergio, Beltrame, Luca, Tognon, Germana, D'Incalci, Maurizio, Pecorelli, Sergio, Sartori, Enrico, Odicino, Franco, Ravaggi, Antonella, Bignotti, Eliana

“…The existence of cancer stem cells (CSCs) within a tumor bulk has been demonstrated for many solid tumors including epithelial ovarian carcinoma (EOC). CSCs…”
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The novel atypical retinoid ST1926 is active in ATRA resistant neuroblastoma cells acting by a different mechanism by Di Francesco, Angela Maria, Meco, Daniela, Torella, Anna Rita, Barone, Giuseppe, D’Incalci, Maurizio, Pisano, Claudio, Carminati, Paolo, Riccardi, Riccardo

“…E-3-(4′-Hydroxy-3′-adamantylbiphenyl-4-yl)acrylic acid (ST1926) is a novel orally available compound belonging to the class of synthetic atypical retinoids…”
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