Search Results - "Długosz, A"

Osteogenic differentiation of human adipose-derived stem cells in 3D conditions - comparison of spheroids and polystyrene scaffolds by Rumiński, S, Kalaszczyńska, I, Długosz, A, Lewandowska-Szumieł, M

“…Expansion and differentiation of adipose-derived stem cells (ADSCs) in vitro are routinely performed in two-dimensional (2D) environments. The study hypothesis…”
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The Lack of Influence of Homozygous Long Allele of the 5-HTTLPR Gene on the Severity of Alcohol Craving During 6 Weeks of Rehab Hospitalisation in Comparison to Not Homozygous and Homozygous Short Alleles - Preliminary Report by Czarnecki, Damian, Ziółkowski, Marcin, Chodkiewicz, Jan, Gorzkiewicz, Marta, Waszkiewicz, Napoleon, Długosz, Anna, Budzyński, Jacek, Junkiert-Czarnecka, Anna, Kułak-Bejda, Agnieszka

“…The aim of this study was to assess changes in the severity of alcohol craving according to allelic variants of the 5-HTTLPR gene polymorphism during…”
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Genomic Analysis of Smoothened Inhibitor Resistance in Basal Cell Carcinoma by Sharpe, Hayley J., Pau, Gregoire, Dijkgraaf, Gerrit J., Basset-Seguin, Nicole, Modrusan, Zora, Januario, Thomas, Tsui, Vickie, Durham, Alison B., Dlugosz, Andrzej A., Haverty, Peter M., Bourgon, Richard, Tang, Jean Y., Sarin, Kavita Y., Dirix, Luc, Fisher, David C., Rudin, Charles M., Sofen, Howard, Migden, Michael R., Yauch, Robert L., de Sauvage, Frederic J.

“…Smoothened (SMO) inhibitors are under clinical investigation for the treatment of several cancers. Vismodegib is approved for the treatment of locally advanced…”
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Obesity accelerates hair thinning by stem cell-centric converging mechanisms by Morinaga, Hironobu, Mohri, Yasuaki, Grachtchouk, Marina, Asakawa, Kyosuke, Matsumura, Hiroyuki, Oshima, Motohiko, Takayama, Naoya, Kato, Tomoki, Nishimori, Yuriko, Sorimachi, Yuriko, Takubo, Keiyo, Suganami, Takayoshi, Iwama, Atsushi, Iwakura, Yoichiro, Dlugosz, Andrzej A., Nishimura, Emi K.

“…Obesity is a worldwide epidemic that predisposes individuals to many age-associated diseases, but its exact effects on organ dysfunction are largely unknown 1…”
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Basal Cell Carcinoma Preferentially Arises from Stem Cells within Hair Follicle and Mechanosensory Niches by Peterson, Shelby C., Eberl, Markus, Vagnozzi, Alicia N., Belkadi, Abdelmadjid, Veniaminova, Natalia A., Verhaegen, Monique E., Bichakjian, Christopher K., Ward, Nicole L., Dlugosz, Andrzej A., Wong, Sunny Y.

“…Basal cell carcinoma (BCC) is characterized by frequent loss of PTCH1, leading to constitutive activation of the Hedgehog pathway. Although the requirement for…”
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Cancer-Associated Fibroblasts Promote Aggressive Gastric Cancer Phenotypes via Heat Shock Factor 1-Mediated Secretion of Extracellular Vesicles by Grunberg, Nil, Pevsner-Fischer, Meirav, Goshen-Lago, Tal, Diment, Judith, Stein, Yaniv, Lavon, Hagar, Mayer, Shimrit, Levi-Galibov, Oshrat, Friedman, Gil, Ofir-Birin, Yifat, Syu, Li-Jyun, Migliore, Cristina, Shimoni, Eyal, Stemmer, Salomon M, Brenner, Baruch, Dlugosz, Andrzej A, Lyden, David, Regev-Rudzki, Neta, Ben-Aharon, Irit, Scherz-Shouval, Ruth

“…Gastric cancer is the third most lethal cancer worldwide, and evaluation of the genomic status of gastric cancer cells has not translated into effective…”
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Keratin 17 promotes epithelial proliferation and tumor growth by polarizing the immune response in skin by Coulombe, Pierre A, DePianto, Daryle, Kerns, Michelle L, Dlugosz, Andrzej A

“…Basaloid skin tumors, including basal cell carcinoma (BCC) and basaloid follicular hamartoma, are associated with aberrant Hedgehog (Hh) signaling and, in the…”
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Lipid peroxidation stimulated by Solvesso, Bawanol and methanol, and its counteraction by antioxidants in human placental mitochondria by Długosz, A, Piotrowska, D

“…The influence of some solvents used in the paint and lacquer industry, Solvesso 100, 150 and Bawanol, on the process of lipid peroxidation was evaluated. The…”
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Dual and opposing roles of primary cilia in medulloblastoma development by Alvarez-Buylla, Arturo, Han, Young-Goo, Kim, Hong Joo, Dlugosz, Andrzej A, Ellison, David W, Gilbertson, Richard J

“…Recent work has shown that primary cilia are essential for Hedgehog (Hh) signaling during mammalian development. It is also known that aberrant Hh signaling…”
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Primary cilia can both mediate and suppress Hedgehog pathway-dependent tumorigenesis by Reiter, Jeremy F, Wong, Sunny Y, Seol, Allen D, So, Po-Lin, Ermilov, Alexandre N, Bichakjian, Christopher K, Epstein, Ervin H, Dlugosz, Andrzej A

“…Primary cilia are present on most mammalian cells and are implicated in transducing Hedgehog (Hh) signals during development; however, the prevalence of cilia…”
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Increased Prevalence of Rare Sucrase-isomaltase Pathogenic Variants in Irritable Bowel Syndrome Patients by Garcia-Etxebarria, Koldo, Zheng, Tenghao, Bonfiglio, Ferdinando, Bujanda, Luis, Dlugosz, Aldona, Lindberg, Greger, Schmidt, Peter T., Karling, Pontus, Ohlsson, Bodil, Simren, Magnus, Walter, Susanna, Nardone, Gerardo, Cuomo, Rosario, Usai-Satta, Paolo, Galeazzi, Francesca, Neri, Matteo, Portincasa, Piero, Bellini, Massimo, Barbara, Giovanni, Jonkers, Daisy, Eswaran, Shanti, Chey, William D., Kashyap, Purna, Chang, Lin, Mayer, Emeran A., Wouters, Mira M., Boeckxstaens, Guy, Camilleri, Michael, Franke, Andre, D’Amato, Mauro

“…Patients with irritable bowel syndrome (IBS) often associate their symptoms to certain foods. In congenital sucrase-isomaltase deficiency (CSID), recessive…”
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Maintenance of Taste Organs Is Strictly Dependent on Epithelial Hedgehog/GLI Signaling by Ermilov, Alexandre N, Kumari, Archana, Li, Libo, Joiner, Ariell M, Grachtchouk, Marina A, Allen, Benjamin L, Dlugosz, Andrzej A, Mistretta, Charlotte M

“…For homeostasis, lingual taste papilla organs require regulation of epithelial cell survival and renewal, with sustained innervation and stromal interactions…”
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Preliminary Evaluation of the Diagnostic Usefulness of Uroplakin 2 with an Assessment of the Antioxidant Potential of Patients with Bladder Cancer by Dembowski, J., Małkiewicz, B., Długosz, A., Szymańska, B., Matuszewski, M., Piwowar, Agnieszka

“…Background. Urothelial carcinoma is the most common type of bladder cancer (BC). It makes up more than 90% of all bladder cancers. Uroplakins are…”
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Uroplakin IIIa Is a Marker in Bladder Cancer but Seems Not to Reflect Chemical Carcinogenesis by Zdrojowy, Romuald, Dembowski, J., Matuszewski, M., Szymańska, B., Długosz, A.

“…Background. Uroplakins are glycoproteins investigated as potential markers of urothelial carcinoma. However, their role in chemical carcinogenesis is…”
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Hedgehog/Ras interactions regulate early stages of pancreatic cancer by Pasca di Magliano, Marina, Sekine, Shigeki, Ermilov, Alexandre, Ferris, Jenny, Dlugosz, Andrzej A, Hebrok, Matthias

“…Pancreatic ductal adenocarcinoma (PDA) constitutes a lethal disease that affects >30,000 people annually in the United States. Deregulation of Hedgehog…”
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Multiple Shh signaling centers participate in fungiform papilla and taste bud formation and maintenance by Liu, Hong Xiang, Ermilov, Alexandre, Grachtchouk, Marina, Li, Libo, Gumucio, Deborah L., Dlugosz, Andrzej A., Mistretta, Charalotte M.

“…The adult fungiform taste papilla is a complex of specialized cell types residing in the stratified squamous tongue epithelium. This unique sensory organ…”
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Niche-Specific Factors Dynamically Regulate Sebaceous Gland Stem Cells in the Skin by Veniaminova, Natalia A., Grachtchouk, Marina, Doane, Owen J., Peterson, Jamie K., Quigley, David A., Lull, Madison V., Pyrozhenko, Daryna V., Nair, Raji R., Patrick, Matthew T., Balmain, Allan, Dlugosz, Andrzej A., Tsoi, Lam C., Wong, Sunny Y.

“…Oil-secreting sebaceous glands (SGs) are critical for proper skin function; however, it remains unclear how different factors act together to modulate SG stem…”
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Increased serum levels of lipopolysaccharide and antiflagellin antibodies in patients with diarrhea‐predominant irritable bowel syndrome by Dlugosz, A., Nowak, P., D'Amato, M., Mohammadian Kermani, G., Nyström, J., Abdurahman, S., Lindberg, G.

“…Background Innate immune responses to conserved microbial products such as lipopolysaccharide (LPS) and flagellin are likely important in microbial–host…”
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Distinct mechanisms for sebaceous gland self-renewal and regeneration provide durability in response to injury by Veniaminova, Natalia A., Jia, Yunlong Y., Hartigan, Adrien M., Huyge, Thomas J., Tsai, Shih-Ying, Grachtchouk, Marina, Nakagawa, Seitaro, Dlugosz, Andrzej A., Atwood, Scott X., Wong, Sunny Y.

“…Sebaceous glands (SGs) release oils that protect our skin, but how these glands respond to injury has not been previously examined. Here, we report that SGs…”
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Next generation sequencing of Cytokeratin 20-negative Merkel cell carcinoma reveals ultraviolet-signature mutations and recurrent TP53 and RB1 inactivation by Harms, Paul W, Collie, Angela M B, Hovelson, Daniel H, Cani, Andi K, Verhaegen, Monique E, Patel, Rajiv M, Fullen, Douglas R, Omata, Kei, Dlugosz, Andrzej A, Tomlins, Scott A, Billings, Steven D

“…Merkel cell carcinoma is a rare but highly aggressive cutaneous neuroendocrine carcinoma. Cytokeratin 20 (CK20) is expressed in ~95% of Merkel cell carcinomas…”
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