Search Results - "Düzgüneş, N."

Cellular changes, molecular pathways and the immune system following photodynamic treatment by Skupin-Mrugalska, P, Sobotta, L, Kucinska, M, Murias, M, Mielcarek, J, Düzgüneş, N

“…Photodynamic therapy (PDT) is a novel medical technique involving three key components: light, a photosensitizer molecule and molecular oxygen, which are…”
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Cationic liposomes for gene delivery: from biophysics to biological applications by Pedroso de Lima, M C, Neves, S, Filipe, A, Düzgüneş, N, Simões, S

“…The use of an efficient carrier for nucleic acid-based medicines is considered to be a determinant factor for the successful application of gene therapy. The…”
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Gene delivery by negatively charged ternary complexes of DNA, cationic liposomes and transferrin or fusigenic peptides by SIMOES, S, SLEPUSHKIN, V, GASPAR, R, PEDROSO DE LIMA, M. C, DÜZGÜNES, N

“…Potential problems with the use of viral vectors for gene therapy necessitate the development of efficient nonviral vectors. The association of transferrin, or…”
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Mechanisms of gene transfer mediated by lipoplexes associated with targeting ligands or pH-sensitive peptides by SIMOES, S, SLEPUSHKIN, V, PIRES, P, GASPAR, R, PEDROSODELIMA, M. C, DÜZGÜNES, N

“…Association of a targeting ligand such as transferrin, or an endosome disrupting peptide such as GALA, with cationic liposome-DNA complexes ('lipoplexes')…”
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Transferrin lipoplex-mediated suicide gene therapy of oral squamous cell carcinoma in an immunocompetent murine model and mechanisms involved in the antitumoral response by Neves, S, Faneca, H, Bertin, S, Konopka, K, Düzgüneş, N, Pierrefite-Carle, V, Simões, S, Pedroso de Lima, M C

“…Suicide gene therapy has been used for the treatment of a variety of cancers. We reported previously the in vitro efficacy of the Herpes Simplex Virus…”
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Efficient gene transfer by transferrin lipoplexes in the presence of serum by Tros de Ilarduya, C., Düzgüneş, N.

“…Cationic lipids are being used increasingly as reagents for gene delivery both in vitro and in vivo. One of the limitations to the application of cationic…”
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Enhanced gene delivery in vitro and in vivo by improved transferrin-lipoplexes by Tros de Ilarduya, C., Arangoa, M.A., Moreno-Aliaga, M.J., Düzgüneş, N.

“…Cationic liposomes and the complexes they form with DNA (lipoplexes) constitute the most promising alternative to the use of viral vectors for gene therapy…”
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Sterically Stabilized pH-sensitive Liposomes, INTRACELLULAR DELIVERY OF AQUEOUS CONTENTS AND PROLONGED CIRCULATION IN VIVO by Slepushkin, Vladimir A., Simões, Sérgio, Dazin, Paul, Newman, Mary S., Guo, Luke S., de Lima, Maria C. Pedroso, Düzgüneş, Nejat

“…Liposomes that destabilize at mildly acidic pH are efficient tools for delivering water-soluble drugs into the cell cytoplasm. However, their use in vivo is…”
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The Shape Parameter of Liposomes and DNA-Lipid Complexes Determined by Viscometry Utilizing Small Sample Volumes by Sun, Y., Li, X., Düzgüneşν, N., Takaoka, Y., Ohi, S., Hirota, S.

“…A minicapillary viscometer utilizing <0.5 ml of sample at a volume fraction of <0.1% is described. The calculated a/b of DPPC/DPPG multilamellar liposome was…”
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Influence of antifungal polyenes on the adhesion of Candida albicans and Candida glabrata to human epithelial cells in vitro by Dorocka-Bobkowska, B, Konopka, K, Düzgüneş, N

“…Candidal adherence to mucosal surfaces is considered as the first step in the pathogenesis of oral candidiasis. We examined the effect of antifungal polyenes,…”
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Transfection of human macrophages by lipoplexes via the combined use of transferrin and pH-sensitive peptides by Simões, Sergio, Slepushkin, Vladimir, Pretzer, Elizabeth, Dazin, Paul, Gaspar, Rogério, Lima, Maria C. Pedroso, Düzgüneş, Nejat

“…The crucial function of macrophages in a variety of biological processes and pathologies render these cells important targets for gene therapeutic…”
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Transferrin-lipoplexes with protamine-condensed DNA for serum-resistant gene delivery by Tros de Ilarduya, C, Arangoa, M A, Düzgüneş, N

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Efficacies of liposome-encapsulated streptomycin and ciprofloxacin against Mycobacterium avium-M. intracellulare complex infections in human peripheral blood monocyte/macrophages by MAJUMDAR, S, FLASHER, D, FRIEND, D. S, NASSOS, P, YAJKO, D, HADLEY, W. K, DÜZGÜNES, N

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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D-4F, an apoA-1 mimetic, decreases airway hyperresponsiveness, inflammation, and oxidative stress in a murine model of asthma[S] by Nandedkar, S.D., Weihrauch, D., Xu, H., Shi, Y., Feroah, T., Hutchins, W., Rickaby, D.A., Duzgunes, N., Hillery, C.A., Konduri, K.S., Pritchard, Jr.K.A.

“…Asthma is characterized by oxidative stress and inflammation of the airways. Although proinflammatory lipids are involved in asthma, therapies targeting them…”
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Increased receptor-mediated gene delivery to the liver by protamine-enhanced-asialofetuin-lipoplexes by ARANGOA, M. A, DÜZGÜNES, N, TROS DE ILARDUYA, C

“…A novel lipidic vector composed of DOTAP/Chol liposomes, asialofetuin (AF), protamine sulfate and DNA has been developed. The resulting protamine-AF-lipoplexes…”
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Therapy of Mycobacterium avium complex infections in beige mice with streptomycin encapsulated in sterically stabilized liposomes by GANGADHARAM, P. R. J, ASHTEKAR, D. R, FLASHER, D. L, DÜZGÜNES, N

“…Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon…”
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Treatment of intracellular Mycobacterium avium complex infection by free and liposome-encapsulated sparfloxacin by Düzgüneş, N, Flasher, D, Reddy, M V, Luna-Herrera, J, Gangadharam, P R

“…Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon…”
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Cationic porphyrin-mediated photodynamic inactivation of Candida biofilms and the effect of miconazole by Davies, A, Gebremedhin, S, Yee, M, Padilla, R J, Duzgunes, N, Konopka, K, Dorocka-Bobkowska, B

“…The formation of biofilms by Candida and the increasing resistance of Candida species to antifungals contribute to the high recurrence rates of denture…”
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Miconazole activity against Candida biofilms developed on acrylic discs by Gebremedhin, S, Dorocka-Bobkowska, B, Prylinski, M, Konopka, K, Duzgunes, N

“…Oral candidiasis in the form of Candida-associated denture stomatitis (CaDS) is associated with Candida adhesion and biofilm formation on the fitting surface…”
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Gene delivery mediated by cationic liposomes: from biophysical aspects to enhancement of transfection by de Lima, M C, Simões, S, Pires, P, Gaspar, R, Slepushkin, V, Düzgüneş, N

“…Cationic liposomes complexed with DNA have been used extensively as non-viral vectors for the intracellular delivery of reporter or therapeutic genes in…”
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