Search Results - "Döskaya, Mert"
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In silico discovery of antigenic proteins and epitopes of SARS-CoV-2 for the development of a vaccine or a diagnostic approach for COVID-19
Published in Scientific reports (28-12-2020)“…In the genome of SARS-CoV-2, the 5′-terminus encodes a polyprotein, which is further cleaved into 15 non-structural proteins whereas the 3′ terminus encodes…”
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Genotyping of Enterocytozoon bieneusi isolates detected in stray cats of İzmir, Türkiye
Published in Parasitology research (1987) (01-11-2023)“…The phylum Microsporidia includes obligate intracellular parasites that can infect humans and various animals. To date, 17 different species within the phylum…”
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Development of a novel recombinant ELISA for the detection of Crimean-Congo hemorrhagic fever virus IgG antibodies
Published in Scientific reports (15-03-2021)“…Crimean-Congo hemorrhagic fever (CCHF) is a tick-borne viral infection caused by Crimean-Congo hemorrhagic fever virus (CCHFV). Serological screening of CCHF…”
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Prevalence of toxoplasmosis and genetic characterization of Toxoplasma gondii strains isolated in wild birds of prey and their relation with previously isolated strains from Turkey
Published in PloS one (18-04-2018)“…Toxoplasma gondii is a protozoon parasite that causes congenital toxoplasmosis, as well as other serious clinical presentations, in immune compromised humans…”
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High frequency of knockdown resistance mutations in the para gene of cat flea (Ctenocephalides felis) samples collected from goats
Published in Parasitology research (1987) (01-07-2020)“…Fleas are ectoparasites of mammals and birds. In livestock such as sheep and goat, flea bites cause many clinical signs. Several types of insecticides…”
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Investigation of the role of stray cats for transmission of toxoplasmosis to humans and animals living in İzmir, Turkey
Published in Journal of infection in developing countries (31-01-2021)“…Toxoplasma gondii is a protozoan parasite that has a widespread distribution among mammalians and birds. One of the reasons for the high prevalence may be due…”
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GRA1 protein vaccine confers better immune response compared to codon-optimized GRA1 DNA vaccine
Published in Vaccine (26-02-2007)“…Abstract The present study evaluates immunogenicity and protection potency of a codon-optimized GRA1 DNA vaccine, wild type GRA1 DNA vaccine and an adjuvanted…”
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The biomarker features of miR-145-3p determined via meta-analysis validated by qRT-PCR in metastatic cancer cell lines
Published in Gene (20-08-2019)“…MicroRNAs (miRNAs) play important roles in the cancer biology such as proliferation, differentiation, and apoptosis. The pivotal roles that miRNA expression…”
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Mitotyping of random bred cats and pure breed cats (Turkish Angora and Turkish Van) using non-repetitive mitochondrial DNA control region
Published in Gene (20-01-2024)“…•We aimed to investigate the mitotype diversity in random bred cats and locally recognized pure breeds, namely the Turkish Angora and Turkish Van.•Our analysis…”
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Development of a “Rapid-Crypto Colorimetric LAMP Test” to Detect Cryptosporidiosis in Feces of Newborns Calves
Published in Acta parasitologica (01-03-2024)“…Background Cryptosporidiosis is a disease that causes major intestinal damage in humans and animals. The causative agents of the disease are Cryptosporidium…”
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Immunogenicity and protection efficacy of a COVID-19 DNA vaccine encoding spike protein with D614G mutation and optimization of large-scale DNA vaccine production
Published in Scientific reports (15-06-2024)“…Severe acute respiratory syndrome coronavirus 2 had devastating consequences for human health. Despite the introduction of several vaccines, COVID-19 continues…”
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Molecular characterization of cytidine monophospho-N-acetylneuraminic acid hydroxylase (CMAH) gene and frequency of blood types in stray cats of İzmir, Turkey
Published in BMC genomics (19-04-2021)“…Cytidine monophospho-n-acetylneuraminic acid hydroxylase (CMAH) gene associated with blood groups in cats encodes CMAH enzyme that converts Neu5Ac to Neu5Gc…”
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Molecular prevalence and genotypes of Enterocytozoon bieneusi in cancer patients under chemotherapy in Aegean region of Türkiye
Published in BMC microbiology (26-06-2024)“…Enterocytozoon bieneusi is the most common species found in humans. Although E. bieneusi has been investigated in humans, genotype profile of E. bieneusi is…”
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Molecular prevalence and genetic diversity of Bartonella spp. in stray cats of İzmir, Turkey
Published in Parasites & vectors (29-08-2022)“…Bartonella spp. are vector-borne pathogens that cause zoonotic infections in humans. One of the most well-known of these is cat-scratch disease caused by…”
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Do Toxoplasma gondii apicoplast proteins have antigenic potential? An in silico study
Published in Computational biology and chemistry (01-02-2020)“…[Display omitted] •Apicoplast proteins were first time analyzed to reveal whether its proteins have an antigenic potential.•It was found that 19 apicoplast…”
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Molecular prevalence and subtyping of Cryptosporidium spp. in fecal samples collected from stray cats in İzmir, Turkey
Published in BMC veterinary research (07-03-2022)“…Cryptosporidium spp. are obligate intracellular apicomplexan parasites transmitted to humans and other animals by contaminated water, food, or direct contact…”
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Immunogenicity of a xenogeneic multi-epitope HER2+ breast cancer DNA vaccine targeting the dendritic cell restricted antigen-uptake receptor DEC205
Published in Vaccine (06-04-2022)“…•Developed a novel highly immunogenic multi-epitope HER2 DNA vaccine.•Designed a novel multi-epitope HER2 protein containing 7T and B-cell epitopes.•Used an…”
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Development of a new serotyping ELISA for Toxoplasma gondii type II, type III and Africa 1 lineages using in silico peptide discovery methods, well categorized feline and human outbreak serum samples
Published in BMC infectious diseases (31-01-2022)“…Discovery of new Toxoplasma gondii serotyping epitopes is important due to reports showing the influence of genotype on the severity of toxoplasmosis. In…”
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Computational identification of monkeypox virus epitopes to generate a novel vaccine antigen against Mpox
Published in Biologicals (01-11-2024)“…Monkeypox virus (MPXV) belonging to poxviridae family causes chronic viral disease in various mammals including human and monkeys. Conventional vaccines…”
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Development of multistage recombinant protein vaccine formulations against toxoplasmosis using a new chitosan and porin based adjuvant system
Published in International journal of pharmaceutics (15-10-2022)“…[Display omitted] •Introducing a new particulate adjuvant system based on combination of chitosan and porins (MicroAS and NanoAS) for delivery of multivalent…”
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