Search Results - "Döring, Barbara"

Kinetics of the bile acid transporter and hepatitis B virus receptor Na+ /taurocholate cotransporting polypeptide (NTCP) in hepatocytes by König, Alexander, Döring, Barbara, Mohr, Christina, Geipel, Andreas, Geyer, Joachim, Glebe, Dieter

“…Background & Aims The human liver bile acid transporter Na+ /taurocholate cotransporting polypeptide (NTCP) has recently been identified as liver-specific…”
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Characterisation of the hepatitis B virus cross-species transmission pattern via Na+/taurocholate co-transporting polypeptides from 11 New World and Old World primate species by Müller, Simon F, König, Alexander, Döring, Barbara, Glebe, Dieter, Geyer, Joachim

“…The hepatic Na+/taurocholate co-transporting polypeptide (NTCP in man, Ntcp in animals) is the high-affinity receptor for the hepatitis B (HBV) and hepatitis D…”
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Substrate Specificities and Inhibition Pattern of the Solute Carrier Family 10 Members NTCP, ASBT and SOAT by Grosser, Gary, Müller, Simon Franz, Kirstgen, Michael, Döring, Barbara, Geyer, Joachim

“…Three carriers of the solute carrier family SLC10 have been functionally characterized so far. Na + /taurocholate cotransporting polypeptide NTCP is a hepatic…”
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Extrahepatic metabolism at the body's internal-external interfaces by Gundert-Remy, Ursula, Bernauer, Ulrike, Blömeke, Brunhilde, Döring, Barbara, Fabian, Eric, Goebel, Carsten, Hessel, Stefanie, Jäckh, Christine, Lampen, Alfonso, Oesch, Franz, Petzinger, Ernst, Völkel, Wolfgang, Roos, Peter H.

“…Abstract In general, xenobiotic metabolizing enzymes (XMEs) are expressed in lower levels in the extrahepatic tissues than in the liver, making the former less…”
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Transport of the soy isoflavone daidzein and its conjugative metabolites by the carriers SOAT, NTCP, OAT4, and OATP2B1 by Grosser, Gary, Döring, Barbara, Ugele, Bernhard, Geyer, Joachim, Kulling, Sabine E., Soukup, Sebastian T.

“…Soy isoflavones (IF) are phytoestrogens, which interact with estrogen receptors. They are extensively metabolized by glucuronosyltransferases and…”
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Stress-Induced Upregulation of SLC19A3 is Impaired in Biotin-Thiamine-Responsive Basal Ganglia Disease by Schänzer, Anne, Döring, Barbara, Ondrouschek, Michelle, Goos, Sarah, Garvalov, Boyan K., Geyer, Joachim, Acker, Till, Neubauer, Bernd, Hahn, Andreas

“…Biotin‐thiamine‐responsive basal ganglia disease (BTBGD) is a potentially treatable disorder caused by mutations in the SLC19A3 gene, encoding the human…”
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Membrane transporters for sulfated steroids in the human testis--cellular localization, expression pattern and functional analysis by Fietz, Daniela, Bakhaus, Katharina, Wapelhorst, Britta, Grosser, Gary, Günther, Sabine, Alber, Jörg, Döring, Barbara, Kliesch, Sabine, Weidner, Wolfgang, Galuska, Christina E, Hartmann, Michaela F, Wudy, Stefan A, Bergmann, Martin, Geyer, Joachim

“…Sulfated steroid hormones are commonly considered to be biologically inactive metabolites, but may be reactivated by the steroid sulfatase into biologically…”
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Detection of the nt230[del4] MDR1 mutation in dogs by a fluorogenic 5′ nuclease TaqMan allelic discrimination method by Klintzsch, Stefanie, Meerkamp, Kerstin, Döring, Barbara, Geyer, Joachim

“…For detection of the nt230[del4] MDR1 mutation, a 4-bp deletion in the canine MDR1 (ABCB1) gene, a TaqMan allelic discrimination assay was designed that allows…”
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Breed distribution of the nt230(del4) MDR1 mutation in dogs by Gramer, Irina, Leidolf, Regina, Döring, Barbara, Klintzsch, Stefanie, Krämer, Eva-Maria, Yalcin, Ebru, Petzinger, Ernst, Geyer, Joachim

“…A 4-bp deletion mutation associated with multiple drug sensitivity exists in the canine multidrug resistance ( MDR1) gene. This mutation has been detected in…”
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Cloning and Functional Characterization of Human Sodium-dependent Organic Anion Transporter (SLC10A6) by Geyer, Joachim, Döring, Barbara, Meerkamp, Kerstin, Ugele, Bernhard, Bakhiya, Nadiya, Fernandes, Carla F., Godoy, José R., Glatt, Hansruedi, Petzinger, Ernst

“…We have cloned human sodium-dependent organic anion transporter (SOAT) cDNA, which consists of 1502 bp and encodes a 377-amino acid protein. SOAT shows 42%…”
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Molecular and phylogenetic characterization of a novel putative membrane transporter (SLC10A7), conserved in vertebrates and bacteria by Godoy, José R., Fernandes, Carla, Döring, Barbara, Beuerlein, Knut, Petzinger, Ernst, Geyer, Joachim

“…The ‘Solute Carrier Family SLC10’ consists of six annotated members in humans, comprising two bile acid carriers (SLC10A1 and SLC10A2), one steroid sulfate…”
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Phase 0 and phase III transport in various organs: Combined concept of phases in xenobiotic transport and metabolism by Döring, Barbara, Petzinger, Ernst

“…Abstract The historical phasing concept of drug metabolism and elimination was introduced to comprise the two phases of metabolism: phase I metabolism for…”
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Characterisation of the hepatitis B virus cross-species transmission pattern via Na.sup.+/taurocholate co-transporting polypeptides from 11 New World and Old World primate species by Müller, Simon F, König, Alexander, Döring, Barbara, Glebe, Dieter, Geyer, Joachim

“…The hepatic Na.sup.+ /taurocholate co-transporting polypeptide (NTCP in man, Ntcp in animals) is the high-affinity receptor for the hepatitis B (HBV) and…”
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Transport of steroid 3-sulfates and steroid 17-sulfates by the sodium-dependent organic anion transporter SOAT (SLC10A6) by Grosser, Gary, Bennien, Josefine, Sánchez-Guijo, Alberto, Bakhaus, Katharina, Döring, Barbara, Hartmann, Michaela, Wudy, Stefan A., Geyer, Joachim

“…•SOAT transports the 3’-monosulfates 17α-OH-PREGS, androsterone sulfate, and epiandrosterone sulfate.•SOAT transports the 17’-monosulfates…”
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The SLC10 carrier family: transport functions and molecular structure by Döring, Barbara, Lütteke, Thomas, Geyer, Joachim, Petzinger, Ernst

“…The SLC10 family represents seven genes containing 1-12 exons that encode proteins in humans with sequence lengths of 348-477 amino acids. Although termed…”
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Identification of novel inhibitors of the steroid sulfate carrier ‘sodium-dependent organic anion transporter’ SOAT (SLC10A6) by pharmacophore modelling by Grosser, Gary, Baringhaus, Karl-Heinz, Döring, Barbara, Kramer, Werner, Petzinger, Ernst, Geyer, Joachim

“…The sodium-dependent organic anion transporter SOAT specifically transports sulfated steroid hormones and is supposed to play a role in testicular steroid…”
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The novel putative bile acid transporter SLC10A5 is highly expressed in liver and kidney by Fernandes, Carla F., Godoy, José R., Döring, Barbara, Cavalcanti, Marcia C.O., Bergmann, Martin, Petzinger, Ernst, Geyer, Joachim

“…Here we report the identification, cloning, and characterization of SLC10A5, which is a new member of Solute Carrier Family 10 (SLC10), also known as the…”
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Molecular cloning and functional characterization of the bovine ( Bos taurus) organic anion transporting polypeptide Oatp1a2 (Slco1a2) by Geyer, Joachim, Döring, Barbara, Failing, Klaus, Petzinger, Ernst

“…We describe the cloning, functional characterization and tissue localization of a novel membrane transporter of the OATP/Oatp-gene family obtained from liver…”
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The SLC10 Carrier Family by Döring, Barbara, Lütteke, Thomas, Geyer, Joachim, Petzinger, Ernst

“…The SLC10 family represents seven genes containing 1–12 exons that encode proteins in humans with sequence lengths of 348–477 amino acids. Although termed…”
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Factors that contribute to complications during intrahospital transport of the critically ill by Doring, B L, Kerr, M E, Lovasik, D A, Thayer, T

“…Transporting patients from the protective environment of the intensive care (ICU) unit to other areas of the hospital has become increasingly common since high…”
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