Search Results - "Döcke, W D"

Characterization of ZK 245186, a novel, selective glucocorticoid receptor agonist for the topical treatment of inflammatory skin diseases by Schäcke, H, Zollner, TM, Döcke, WD, Rehwinkel, H, Jaroch, S, Skuballa, W, Neuhaus, R, May, E, Zügel, U, Asadullah, K

“…Background and purpose:  Glucocorticoids are highly effective in the therapy of inflammatory diseases. Their value, however, is limited by side effects. The…”
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Interleukin-10 receptor-1 expression in monocyte-derived antigen-presenting cell populations: dendritic cells partially escape from IL-10's inhibitory mechanisms by von Lanzenauer, S H, Wolk, K, Höflich, C, Kunz, S, Grünberg, B H, Döcke, W-D, Reineke, U, Asadullah, K, Sterry, W, Volk, H-D, Sabat, R

“…Interleukin (IL)-10 is an important immunoregulatory cytokine that mediates its effects via a transmembrane receptor complex consisting of two different…”
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Subclinical activation of latent cytomegalovirus (CMV) infection and anti-CMV immune response in patients with atopic dermatitis by Döcke, W.-D., Kiessling, C., Worm, M., Friedrich, M., Pruss, A., Weitz, M., Prösch, S., Kern, F., Volk, H-D., Sterry, W., Asadullah, K.

“…Summary Background Microbiological infections are considered to be of pathophysiological importance in atopic dermatitis (AD). As yet, no information is…”
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Mechanisms of endotoxin tolerance in patients with alcoholic liver cirrhosis: role of interleukin 10, interleukin 1 receptor antagonist, and soluble tumour necrosis factor receptors as well as effector cell desensitisation by von Baehr, V, Döcke, W-D, Plauth, M, Liebenthal, C, Küpferling, S, Lochs, H, Baumgarten, R, Volk, H-D

“…BACKGROUND In patients with alcoholic liver cirrhosis, endotoxaemia is a frequent finding. Unknown mechanisms, however, prevent typical clinical symptoms of…”
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Interleukin-10 in cutaneous disorders : implications for its pathophysiological importance and therapeutic use by ASADULLAH, K, SABAT, R, WIESE, A, DÖCKE, W.-D, VOLK, H.-D, STERRY, W

“…With its antiinflammatory and immunosuppressive properties interleukin-10 (IL-10) plays a dominant role in several immune reactions including regulatory…”
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IL-15 and IL-16 overexpression in cutaneous T-cell lymphomas: stage-dependent increase in mycosis fungoides progression by Asadullah, K., Haeußler-Quade, A., Gellrich, S., Hanneken, S., Hansen-Hagge, T. E., Döcke, W.-D., Volk, H.-D., Sterry, W.

“…: Cytokines are of major importance for the pathogenesis of cutaneous T‐cell lymphomas (CTCL). Recent data suggested that IL‐15 and IL‐16 are survival/growth…”
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Massive elevation of procalcitonin plasma levels in the absence of infection in kidney transplant patients treated with pan-T-cell antibodies by SABAT, Robert, HÖFLICH, Conny, DÖCKE, Wolf-Dietrich, OPPERT, Michael, KERN, Florian, WINDRICH, Bettina, ROSENBERGER, Christian, KADEN, Jürgen, VOLK, Hans-Dieter, REINKE, Petra

“…To determine the value of procalcitonin (PCT) monitoring in transplant patients receiving pan-T-cell antibody therapy. Retrospective clinical study. A…”
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Erratum: Interleukin-10 receptor-1 expression in monocyte-derived antigen-presenting cell populations: dendritic cells partially escape from IL-10's inhibitory mechanisms by von Haehling, S, Wolk, K, Höflich, C, Kunz, S, Grünberg, B H, Döcke, W-D, Reineke, U, Asadullah, K, Sterry, W, Volk, H-D, Sabat, R

“…Correction to: Genes and Immunity (2015) 16, 8–14; doi:10.1038/gene.2014.69; published online 4 December 2014 Following the publication of this paper, the…”
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Interleukin-10 receptor-1 expression in monocyte-derived antigen-presenting cell populations: dendritic cells partially escape from IL-10's inhibitory mechanisms by von Haehling, S, Wolk, K, Höflich, C, Kunz, S, Grünberg, B H, Döcke, W-D, Reineke, U, Asadullah, K, Sterry, W, Volk, H-D, Sabat, R

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Very low monocytic HLA-DR expression indicates high risk of infection--immunomonitoring for patients after neurosurgery and patients during high dose steroid therapy by Asadullah, K, Woiciechowsky, C, Döcke, W D, Egerer, K, Kox, W J, Vogel, S, Sterry, W, Volk, H D

“…In patients with disturbed immunoreactivity caused by trauma or immunosuppressive therapy infections are still a severe problem. To determine whether…”
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IL-10 is a key cytokine in psoriasis. Proof of principle by IL-10 therapy: a new therapeutic approach by Asadullah, K, Sterry, W, Stephanek, K, Jasulaitis, D, Leupold, M, Audring, H, Volk, H D, Döcke, W D

“…Overexpression of proinflammatory, type 1 cytokines has been demonstrated in psoriasis and is believed to be of pathophysiological importance. IL-10 is a type…”
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Long-term interleukin-10 presence induces the development of a novel, monocyte-derived cell type by Schoenbein, C, Docke, W.-D, Wolk, K, Belbe, G, Hoflich, C, Jung, M, Grutz, G, Sterry, W, Volk, H.-D, Asadullah, K, Sabat, R

“…Interleukin (IL)-10 is one of the most crucial immunoregulatory cytokines. Its short-term effects have been analysed extensively, but little is known about its…”
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Hemodynamic effects of Immunoadsorption and subsequent immunoglobulin substitution in dilated cardiomyopathy three-month results from a randomized study by FELIX, S. B, STAUDT, A, WALLUKAT, G, STANGL, K, BAUMANN, G, DÖRFFEL, W. V, STANGL, V, MERKEL, K, POHL, M, DOCKE, W. D, MORGERA, S, NEUMAYER, H. H, WERNECKE, K. D

“…The objective of our study was to assess the hemodynamic effects of immunoadsorption (IA) and subsequent immunoglobulin G (IgG) substitution in comparison with…”
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Effect of granulocyte colony-stimulating factor treatment on ex vivo blood cytokine response in human volunteers by HARTUNG, T, DÖCKE, W.-D, GANTNER, F, KRIEGER, G, SAUER, A, STEVENS, P, VOLK, H.-D, WENDEL, A

“…We explored the ex vivo alteration in the cytokine release of stimulated blood taken from healthy volunteers treated subcutaneously with 480 micrograms…”
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Cytomegalovirus reactivation and tumour necrosis factor by Döcke, W D, Prösch, S, Fietze, E, Kimel, V, Zuckermann, H, Klug, C, Syrbe, U, Krüger, D H, von Baehr, R, Volk, H D

“…Tumour necrosis factor-alpha (TNF) stimulates cytomegalovirus (CMV) activity in a transfected human monocytic cell line. We assessed whether this finding is…”
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Flow cytometric characterization of lesional T cells in psoriasis : intracellular cytokine and surface antigen expression indicates an activated, memory/effector type 1 immunophenotype by FRIEDRICH, M, KRAMMIG, S, HENZE, M, DOCKE, W. D, STERRY, W, ASADULLAH, K

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Cytomegalovirus infection and common variable immunodeficiency by Döcke, W D, Simon, H U, Fietze, E, Prösch, S, Diener, C, Reinke, P, Stein, H, Volk, H D

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Monocyte deactivation--rationale for a new therapeutic strategy in sepsis by Volk, H D, Reinke, P, Krausch, D, Zuckermann, H, Asadullah, K, Müller, J M, Döcke, W D, Kox, W J

“…Inflammatory cells, in particular monocytes/macrophages, release pro-inflammatory mediators in response to several infectious and non-infectious stimuli. The…”
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Mechanisms of brain-mediated systemic anti-inflammatory syndrome causing immunodepression by WOICIECHOWSKY, C, SCHÖNING, B, LANKSCH, W. R, VOLK, H.-D, DÖCKE, W.-D

“…Overwhelming inflammatory immune response can result in systemic inflammation and septic shock. To prevent excessive and deleterious action of proinflammatory…”
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Induction of long-term survival of rat skin allografts by a novel, highly efficient anti-CD4 monoclonal antibody by Lehmann, M, Sternkopf, F, Metz, F, Brock, J, Döcke, W D, Plantikow, A, Kuttler, B, Hahn, H J, Ringel, B, Volk, H D

“…The new monoclonal antirat CD4 antibody RIB 5/2, which detects another epitope than those covered by W3/25 and MRC OX35, was tested for its immunosuppressive…”
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