Search Results - "Díez-Pérez Adolfo"
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The association between fracture and obesity is site-dependent: A population-based study in postmenopausal women
Published in Journal of bone and mineral research (01-02-2012)“…The association between obesity and fracture is controversial. We investigated the relationship between body mass index (BMI) and fracture at different…”
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Relationship of Weight, Height, and Body Mass Index With Fracture Risk at Different Sites in Postmenopausal Women: The Global Longitudinal Study of Osteoporosis in Women (GLOW)
Published in Journal of bone and mineral research (01-02-2014)“…ABSTRACT Low body mass index (BMI) is a well‐established risk factor for fracture in postmenopausal women. Height and obesity have also been associated with…”
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Microindentation for in vivo measurement of bone tissue material properties in atypical femoral fracture patients and controls
Published in Journal of bone and mineral research (01-01-2013)“…Atypical femoral fractures (AFF) associated with long‐term bisphosphonates (LTB) are a growing concern. Their etiology is unknown, but bone material properties…”
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Ankylosing Spondylitis Is Associated With an Increased Risk of Vertebral and Nonvertebral Clinical Fractures: A Population‐Based Cohort Study
Published in Journal of bone and mineral research (01-08-2014)“…ABSTRACT The objective of this work was to study the associations between ankylosing spondylitis (AS) and clinical vertebral and nonvertebral fractures. Data…”
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The association between fracture site and obesity in men: A population‐Based cohort study
Published in Journal of bone and mineral research (01-08-2013)“…ABSTRACT A site‐dependent association between obesity and fracture has been reported in postmenopausal women. In this study we investigated the relationship…”
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Relationship Between Bone Quantitative Ultrasound and Fractures: A Meta‐Analysis
Published in Journal of bone and mineral research (01-07-2006)“…The relationship between bone QUS and fracture risk was estimated in a systematic review of data from 14 prospective studies of 47,300 individuals and 2350…”
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Increase in Fracture Risk Following Unintentional Weight Loss in Postmenopausal Women: The Global Longitudinal Study of Osteoporosis in Women
Published in Journal of bone and mineral research (01-07-2016)“…ABSTRACT Increased fracture risk has been associated with weight loss in postmenopausal women, but the time course over which this occurs has not been…”
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Assessment of Bone Health in Patients With Type 1 Gaucher Disease Using Impact Microindentation
Published in Journal of bone and mineral research (01-07-2017)“…ABSTRACT Gaucher disease (GD), one of the most common lysosomal disorders (a global population incidence of 1:50,000), is characterized by…”
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Risk Factors for Treatment Failure With Antiosteoporosis Medication: The Global Longitudinal Study of Osteoporosis in Women (GLOW)
Published in Journal of bone and mineral research (01-01-2014)“…ABSTRACT Antiosteoporosis medication (AOM) does not abolish fracture risk, and some individuals experience multiple fractures while on treatment. Therefore,…”
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Functional Assessment of Coding and Regulatory Variants From the DKK1 Locus
Published in JBMR plus (01-12-2020)“…ABSTRACT The DKK1 gene encodes an extracellular inhibitor of the Wnt pathway with an important role in bone tissue development, bone homeostasis, and different…”
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Update on long-term treatment with bisphosphonates for postmenopausal osteoporosis: A systematic review
Published in Bone (New York, N.Y.) (01-01-2014)“…Abstract Introduction Osteoporosis is a progressive skeletal disorder that requires long-term treatment. However, there is little guidance regarding optimal…”
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Effect of IL-1β, PGE2, and TGF-β1 on the expression of OPG and RANKL in normal and osteoporotic primary human osteoblasts
Published in Journal of cellular biochemistry (15-05-2010)“…The RANKL/RANK/OPG pathway is essential for bone remodeling regulation. Many hormones and cytokines are involved in regulating gene expression in most of the…”
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COL1A1 haplotypes and hip fracture
Published in Journal of bone and mineral research (01-04-2012)“…Fragility fractures resulting from low‐trauma events such as a fall from standing height are associated with osteoporosis and are very common in older people,…”
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Effects of teriparatide on hip and upper limb fractures in patients with osteoporosis: A systematic review and meta-analysis
Published in Bone (New York, N.Y.) (01-03-2019)“…In randomized clinical trials (RCTs) with teriparatide, the number of patients with incident hip fractures was small and insufficiently powered to show…”
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Functional relevance of the BMD‐associated polymorphism rs312009: Novel Involvement of RUNX2 in LRP5 transcriptional regulation
Published in Journal of bone and mineral research (01-05-2011)“…LRP5 is an osteoporosis susceptibility gene. Association analyses reveal that individual single‐nucleotide polymorphisms (SNPs) determine variation in bone…”
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Calcium Citrate and Vitamin D in the Treatment of Osteoporosis
Published in Clinical drug investigation (01-05-2011)“…The combination of calcium with vitamin D (vitamin D 3 [colecalciferol]) forms the basis of preventive and therapeutic regimens for osteoporosis. A number of…”
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A Haplotype‐Based Analysis of the LRP5 Gene in Relation to Osteoporosis Phenotypes in Spanish Postmenopausal Women
Published in Journal of bone and mineral research (01-12-2008)“…LRP5 encodes the low‐density lipoprotein receptor‐related protein 5, a transmembrane protein involved in Wnt signaling. LRP5 is an important regulator of…”
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Two New Single‐Nucleotide Polymorphisms in the COL1A1 Upstream Regulatory Region and Their Relationship to Bone Mineral Density
Published in Journal of bone and mineral research (01-03-2002)“…Single‐nucleotide polymorphisms (SNPs) in regulatory regions of candidate genes may determine variability in bone mineral density (BMD) because they may be…”
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Risk factors for a second nonsimultaneous hip fracture in a prospective cohort study
Published in Archives of orthopaedic and trauma surgery (01-10-2022)“…Introduction The risk factors for a second nonsimultaneous hip fracture are unclear, and in general, it is empirically assumed that they are similar to those…”
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Probability of fractures predicted by FRAX® and observed incidence in the Spanish ECOSAP Study cohort
Published in Bone (New York, N.Y.) (01-01-2012)“…Abstract Purpose To assess the ability of the Spanish version of the WHO fracture risk assessment tool (FRAX®) to predict the observed incident fractures in…”
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