Search Results - "Díaz Gil, J"

Liver growth factor treatment reverses emphysema previously established in a cigarette smoke exposure mouse model by Pérez-Rial, Sandra, Del Puerto-Nevado, Laura, Girón-Martínez, Alvaro, Terrón-Expósito, Raúl, Díaz-Gil, Juan J, González-Mangado, Nicolás, Peces-Barba, Germán

“…Chronic obstructive pulmonary disease (COPD) is an inflammatory lung disease largely associated with cigarette smoke exposure (CSE) and characterized by…”
Get more information

Effect of liver growth factor on both testicular regeneration and recovery of spermatogenesis in busulfan-treated mice by Pérez-Crespo, Miriam, Pericuesta, Eva, Pérez-Cerezales, Serafín, Arenas, Maria I, Lobo, Maria V T, Díaz-Gil, Juan J, Gutierrez-Adan, Alfonso

“…Some adult stem cells persist in adult tissue; however, we do not know how to stimulate stem cells in adults to heal injuries. Liver growth factor (LGF) is a…”
Get full text

Short-term treatment of spontaneously hypertensive rats with liver growth factor reduces carotid artery fibrosis, improves vascular function, and lowers blood pressure by SOMOZA, Beatriz, ABDERRAHIM, Fatima, GONZALEZ, José M, CONDE, M. Victoria, ARRIBAS, Silvia M, STARCHER, Barry, REGADERA, Javier, FERNANDEZ-ALFONSO, Maria S, DIAZ-GIL, Juan J, GONZALEZ, M. Carmen

“…Liver growth factor (LGF), a mitogen for liver cells, reduces fibrosis in a rat model of cirrhosis. The present study assesses the possible vascular…”
Get full text

Liver growth factor treatment reverses vascular and plasmatic oxidative stress in spontaneously hypertensive rats by Condezo-Hoyos, Luis, Arribas, Silvia M, Abderrahim, Fátima, Somoza, Beatriz, Gil-Ortega, Marta, Díaz-Gil, Juan J, Conde, M Victoria, Susin, Cristina, González, M Carmen

“…BACKGROUND:Liver growth factor (LGF) is an albumin–bilirubin complex with antioxidant actions in vitro. In spontaneously hypertensive rats (SHRs), short LGF…”
Get full text

A metabolomic approach shows sphingosine 1-phosphate and lysophospholipids as mediators of the therapeutic effect of liver growth factor in emphysema by Navarrete, A., Rupérez, F.J., Mendes, T.O., Pérez-Rial, S., Girón-Martínez, A., Terrón-Expósito, R., Díaz-Gil, J.J., Peces-Barba, G., Barbas, C., García, A.

“…[Display omitted] •Metabolomics study with plasma from mice exposed to tobacco smoke in an emphysema model.•Liver growth factor could be useful to promote lung…”
Get full text

Antioxidant activity of liver growth factor, a bilirubin covalently bound to albumin by Condezo-Hoyos, Luis, Abderrahim, Fatima, Conde, M. Victoria, Susín, Cristina, Díaz-Gil, Juan J., González, M. Carmen, Arribas, Silvia M.

“…We previously reported that treatment of spontaneously hypertensive rats (SHR) with liver growth factor (LGF), an albumin–bilirubin complex with a covalent…”
Get full text

Improvement in liver fibrosis, functionality and hemodynamics in CCl4-cirrhotic rats after injection of the Liver Growth Factor by DIAZ-GIL, J. J, MUNOZ, J, ALBILLOS, A, RUA, C, MACHIN, C, GARCIA-CANERO, R, CERECEDA, R. M, GUIJARRO, M. C, TRILLA, C, ESCARTIN, P

Get full text

Liver growth factor induces testicular regeneration in EDS-treated rats and increases protein levels of class B scavenger receptors by Lobo, M V T, Arenas, M I, Huerta, L, Sacristán, S, Pérez-Crespo, M, Gutiérrez-Adán, A, Díaz-Gil, J J, Lasunción, M A, Martín-Hidalgo, A

“…The aim of the present work was to determine the effects of liver growth factor (LGF) on the regeneration process of rat testes after chemical castration…”
Get more information

Liver growth factor antifibrotic activity in vivo is associated with a decrease in activation of hepatic stellate cells by Díaz-Gil, Juan J, García-Monzón, Carmelo, Rúa, Carmen, Martín-Sanz, Paloma, Cereceda, Rosa M, Miquilena-Colina, María E, Machín, Celia, Fernández-Martínez, Amalia, García-Cañero, Rafael

“…The antifibrotic activity of Liver Growth Factor (LGF), a liver mitogen, was previously demonstrated in several models of rat liver fibrosis and even in…”
Get full text

Sex-dependent effect of liver growth factor on atherosclerotic lesions and fatty liver disease in apolipoprotein E knockout mice by Surra, Joaquín C, Guillén, Natalia, Barranquero, Cristina, Arbonés-Mainar, José M, Navarro, María A, Gascón, Sonia, Arnal, Carmen, Godino, Javier, Guzmán, Mario A, Díaz-Gil, Juan J, Osada, Jesús

“…Since the hepatic mitogen, liver growth factor (LGF), improves vascular structure and function in a hypertensive rat model and exhibits antioxidant activity,…”
Get full text

The anti-fibrotic effect of liver growth factor is associated with decreased intrahepatic levels of matrix metalloproteinases 2 and 9 and transforming growth factor beta 1 in bile duct-ligated rats by Díaz-Gil, Juan J, García-Monzón, Carmelo, Rúa, Carmen, Martín-Sanz, Paloma, Cereceda, Rosa M, Miquilena-Colina, María E, Machín, Celia, Fernández-Martínez, Amalia, García-Cañero, Rarael

“…Liver growth factor (LGF), a mitogen for liver cells, behaves as an anti-fibrotic agent even in extrahepatic sites, but its mechanistic basis is unknown. We…”
Get full text

Liver growth factor as a tissue regenerating factor in neurodegenerative diseases by Gonzalo-Gobernado, Rafael, Calatrava-Ferreras, Lucia, Perucho, Juan, Reimers, Diana, Casarejos, MarIa J, Herranz, Antonio S, Jimenez-Escrig, Adriano, Diaz-Gil, Juan J, Bazan, Eulalia

“…Liver growth factor (LGF) is a hepatic mitogen purified by our group in 1986. In the following years we demonstrated its activity both in "in vivo" and "in…”
Get more information

Liver growth factor treatment restores cell-extracellular matrix balance in resistance arteries and improves left ventricular hypertrophy in SHR by Conde, M Victoria, Gonzalez, M Carmen, Quintana-Villamandos, Begoña, Abderrahim, Fatima, Briones, Ana M, Condezo-Hoyos, Luis, Regadera, Javier, Susin, Cristina, Gomez de Diego, Jose J, Delgado-Baeza, Emilio, Diaz-Gil, Juan J, Arribas, Silvia M

“…Liver growth factor (LGF) is an endogenous albumin-bilirubin complex with antihypertensive effects in spontaneously hypertensive rats (SHR). We assessed the…”
Get more information

Identification of biliprotein as a liver growth factor by Díaz-Gil, J J, Sánchez, G, Trilla, C, Escartín, P

“…We determined the concentration of biliprotein in plasma of rats at different times after partial hepatectomy. From the same plasma samples, we purified a…”
Get more information

The mitogenic activity of the liver growth factor is mediated by tumor necrosis factor alpha in rat liver by Dı́az-Gil, Juan J, Majano, Pedro L, López-Cabrera, Manuel, Sánchez-López, Vicente, Rúa, Carmen, Machı́n, Celia, Trilla, Carolina, Garcı́a-Cañero, Rafael, Moreno-Otero, Ricardo

“…Background/Aims: Liver growth factor (LGF) is a hepatic mitogen, however, the hepatic stimulation pathway remains to be characterized. The aim of this study…”
Get full text

Liver DNA synthesis promoter activity detected in human plasma from subjects with hepatitis by Díaz-Gil, J J, Sánchez, G, Santamaría, L, Trilla, C, Esteban, P, Escartín, P

“…A liver DNA synthesis promoter activity was detected in human plasma from subjects with hepatitis. The assay procedure consisted of intraperitoneal injection…”
Get more information

Na +:H + exchange inhibition induces intracellular acidosis and differentially impairs cell growth and viability of human and rat hepatocarcinoma cells by Garcı́a-Cañero, R., Trilla, C., Pérez de Diego, J., Dı́az-Gil, J.J., Cobo, J.M.

“…Amiloride and its more potent analog, hexamethylene amiloride (HMA), inhibits Na +:H + exchange and decreases intracellular pH in a concentration-dependent way…”
Get full text

Identification of a liver growth factor as an albumin-bilirubin complex by Díaz-Gil, J J, Gavilanes, J G, Sánchez, G, García-Cañero, R, García-Segura, J M, Santamaría, L, Trilla, C, Escartín, P

“…We have reported the purification and characterization of a protein that behaves as a liver growth factor, showing activity either in vivo or in vitro…”
Get full text

Purification of a liver DNA-synthesis promoter from plasma of partially hepatectomized rats by Díaz-Gil, J J, Escartín, P, García-Cañero, R, Trilla, C, Veloso, J J, Sánchez, G, Moreno-Caparrós, A, Enrique de Salamanca, C, Lozano, R, Gavilanes, J G

“…A protein was isolated from plasma of partially (70%) hepatectomized rats that, injected in mice, increases the uptake of [3H]thymidine by liver DNA by…”
Get full text

Serum and cerebrospinal fluid antibodies against myelin basic protein and their IgG subclass distribution in multiple sclerosis by García-Merino, A, Persson, M A, Ernerudh, J, Díaz-Gil, J J, Olsson, T

“…IgG class antibodies reactive with myelin basic protein (MBP) were determined by enzyme-linked immunosorbent assay (ELISA) in serum and cerebrospinal fluid…”
Get full text