Search Results - "Díaz‐Mochón, Juan J."

Number of Nanoparticles per Cell through a Spectrophotometric Method - A key parameter to Assess Nanoparticle-based Cellular Assays by Unciti-Broceta, Juan D., Cano-Cortés, Victoria, Altea-Manzano, Patricia, Pernagallo, Salvatore, Díaz-Mochón, Juan J., Sánchez-Martín, Rosario M.

“…Engineered nanoparticles (eNPs) for biological and biomedical applications are produced from functionalised nanoparticles (NPs) after undergoing multiple…”
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Synthesis and screening of 6‐alkoxy purine analogs as cell type‐selective apoptotic inducers in Jurkat cells by Lorente‐Macías, Álvaro, Iañez, Inmaculada, Jiménez‐López, M. Carmen, Benítez‐Quesada, Manuel, Torres‐Rusillo, Sara, Díaz‐Mochón, Juan J., Molina, Ignacio J., Pineda de las Infantas, María J.

“…Purines are ubiquitous structures in cell biology involved in a multitude of cellular processes, because of which substituted purines and analogs are…”
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Microarray platforms for enzymatic and cell-based assays by Díaz-Mochón, Juan J, Tourniaire, Guilhem, Bradley, Mark

“…This tutorial review introduces the uninitiated to the world of microarrays (or so-called chips) and covers a number of basic concepts such as substrates and…”
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DatAC: A visual analytics platform to explore climate and air quality indicators associated with the COVID-19 pandemic in Spain by Martorell-Marugán, Jordi, Villatoro-García, Juan Antonio, García-Moreno, Adrián, López-Domínguez, Raúl, Requena, Francisco, Merelo, Juan Julián, Lacasaña, Marina, de Dios Luna, Juan, Díaz-Mochón, Juan J., Lorente, Jose A., Carmona-Sáez, Pedro

“…The coronavirus disease 2019 (COVID-19) pandemic has caused an unprecedented global health crisis, with several countries imposing lockdowns to control the…”
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Amplification-free profiling of microRNA-122 biomarker in DILI patient serums, using the luminex MAGPIX system by Marín-Romero, Antonio, Tabraue-Chávez, Mavys, Dear, James W., Sánchez-Martín, Rosario M., Ilyine, Hugh, Guardia-Monteagudo, Juan J., Fara, Mario A., López-Delgado, Francisco J., Díaz-Mochón, Juan J., Pernagallo, Salvatore

“…Dynamic chemical labelling is a single-base specific method to enable detection and quantification of micro-Ribonucleic Acids in biological fluids without…”
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A PCR-free technology to detect and quantify microRNAs directly from human plasma by Marín-Romero, Antonio, Robles-Remacho, Agustín, Tabraue-Chávez, Mavys, López-Longarela, Bárbara, Sánchez-Martín, Rosario M, Guardia-Monteagudo, Juan J, Fara, Mario A, López-Delgado, Francisco J, Pernagallo, Salvatore, Díaz-Mochón, Juan J

“…A novel sensitive, specific and rapid method for the detection and quantification of microRNAs without requiring extraction from their biological sources is…”
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Liquid biopsy beyond of cancer: Circulating pulmonary cells as biomarkers of COPD aggressivity by Romero-Palacios, Pedro J., Alcázar-Navarrete, Bernardino, Díaz Mochón, Juan J., de Miguel-Pérez, Diego, López Hidalgo, Javier L., Garrido-Navas, María del Carmen, Quero Valenzuela, Florencio, Lorente, José Antonio, Serrano, María José

“…Pulmonary parenchymal destruction is consequence of Chronic Obstructive Pulmonary Disease (COPD), which results in degradation of the extracellular matrix and…”
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Poly(ethylmethacrylate-co-diethylaminoethyl acrylate) coating improves endothelial re-population, bio-mechanical and anti-thrombogenic properties of decellularized carotid arteries for blood vessel replacement by López-Ruiz, Elena, Venkateswaran, Seshasailam, Perán, Macarena, Jiménez, Gema, Pernagallo, Salvatore, Díaz-Mochón, Juan J., Tura-Ceide, Olga, Arrebola, Francisco, Melchor, Juan, Soto, Juan, Rus, Guillermo, Real, Pedro J., Diaz-Ricart, María, Conde-González, Antonio, Bradley, Mark, Marchal, Juan A.

“…Decellularized vascular scaffolds are promising materials for vessel replacements. However, despite the natural origin of decellularized vessels, issues such…”
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Dual colour, microarray-based, analysis of 10,000 protease substrates by Díaz-Mochón, Juan J, Bialy, Laurent, Bradley, Mark

“…A 10,000 member PNA-encoded library of FRET based peptides was synthesised for global analysis of protease cleavage specificity; analysis was achieved using a…”
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A 10,000 Member PNA-Encoded Peptide Library for Profiling Tyrosine Kinases by Pouchain, Delphine, Díaz-Mochón, Juan J, Bialy, Laurent, Bradley, Mark

“…A 10,000 member peptide nucleic acid (PNA) encoded peptide library was prepared, treated with the Abelson tyrosine kinase (Abl), and decoded using a DNA…”
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Regioselective One-Pot Synthesis of 9-Alkyl-6-chloropyrido[3,2-e][1,2,4]triazolo[4,3-a]pyrazines. Reactivity of Aliphatic and Aromatic Hydrazides by Unciti-Broceta, Asier, Pineda-de-las-Infantas, Maria J, Díaz-Mochón, Juan J, Romagnoli, Romeo, Baraldi, Pier G, Gallo, Miguel A, Espinosa, Antonio

“…The one-pot synthesis of new 9-alkyl-6-chloropyrido[3,2-e][1,2,4]triazolo[4,3-a]pyrazines has been achieved. Hydrazides regioselectively reacted as…”
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Direct Detection of miR-122 in Hepatotoxicity Using Dynamic Chemical Labeling Overcomes Stability and isomiR Challenges by López-Longarela, Barbara, Morrison, Emma E, Tranter, John D, Chahman-Vos, Lianne, Léonard, Jean-François, Gautier, Jean-Charles, Laurent, Sébastien, Lartigau, Aude, Boitier, Eric, Sautier, Lucile, Carmona-Saez, Pedro, Martorell-Marugan, Jordi, Mellanby, Richard J, Pernagallo, Salvatore, Ilyine, Hugh, Rissin, David M, Duffy, David C, Dear, James W, Díaz-Mochón, Juan J

“…Circulating microRNAs are biomarkers reported to be stable and translational across species. MicroRNA-122 (miR-122) is a hepatocyte-specific microRNA biomarker…”
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Catalytic and Electron Conducting Carbon Nanotube–Reinforced Lysozyme Crystals by Contreras‐Montoya, Rafael, Escolano, Guillermo, Roy, Subhasish, Lopez‐Lopez, Modesto T., Delgado‐López, Jose M., Cuerva, Juan M., Díaz‐Mochón, Juan J., Ashkenasy, Nurit, Gavira, José A., Álvarez de Cienfuegos, Luis

“…Novel reinforced cross‐linked lysozyme crystals containing homogeneous dispersions of single‐walled carbon nanotubes bundles (SWCNTs) are produced and…”
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New Platform for the Direct Profiling of microRNAs in Biofluids by Detassis, Simone, Grasso, Margherita, Tabraue-Chávez, Mavys, Marín-Romero, Antonio, López-Longarela, Bárbara, Ilyine, Hugh, Ress, Cristina, Ceriani, Silvia, Erspan, Mirko, Maglione, Alfredo, Díaz-Mochón, Juan J, Pernagallo, Salvatore, Denti, Michela A

“…Circulating microRNAs have been identified as potential biomarkers for early detection, prognosis, and prediction of several diseases. Their use in clinical…”
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Polymerase-free measurement of microRNA-122 with single base specificity using single molecule arrays: Detection of drug-induced liver injury by Rissin, David M, López-Longarela, Barbara, Pernagallo, Salvatore, Ilyine, Hugh, Vliegenthart, A D Bastiaan, Dear, James W, Díaz-Mochón, Juan J, Duffy, David C

“…We have developed a single probe method for detecting microRNA from human serum using single molecule arrays, with sequence specificity down to a single base,…”
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Insulin Crystals Grown in Short-Peptide Supramolecular Hydrogels Show Enhanced Thermal Stability and Slower Release Profile by Contreras-Montoya, Rafael, Arredondo-Amador, María, Escolano-Casado, Guillermo, Mañas-Torres, Mari C, González, Mercedes, Conejero-Muriel, Mayte, Bhatia, Vaibhav, Díaz-Mochón, Juan J, Martínez-Augustin, Olga, de Medina, Fermín Sánchez, Lopez-Lopez, Modesto T, Conejero-Lara, Francisco, Gavira, José A, de Cienfuegos, Luis Álvarez

“…Protein therapeutics have a major role in medicine in that they are used to treat diverse pathologies. Their three-dimensional structures not only offer higher…”
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Study of antitumor activity in breast cell lines using silver nanoparticles produced by yeast by Ortega, Francisco G, Fernández-Baldo, Martín A, Fernández, Jorge G, Serrano, María J, Sanz, María I, Diaz-Mochón, Juan J, Lorente, José A, Raba, Julio

“…In the present article, we describe a study of antitumor activity in breast cell lines using silver nanoparticles (Ag NPs) synthesized by a microbiological…”
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miR-122 direct detection in human serum by time-gated fluorescence imaging by Garcia-Fernandez, Emilio, Gonzalez-Garcia, M Carmen, Pernagallo, Salvatore, Ruedas-Rama, Maria J, Fara, Mario A, López-Delgado, Francisco J, Dear, James W, Ilyine, Hugh, Ress, Cristina, Díaz-Mochón, Juan J, Orte, Angel

“…A simple method for direct detection of microRNAs (miRs) in human serum without the use of polymerase amplification is presented, achieving low miR-122…”
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Influence of the chirality of short peptide supramolecular hydrogels in protein crystallogenesis by Conejero-Muriel, Mayte, Gavira, José A, Pineda-Molina, Estela, Belsom, Adam, Bradley, Mark, Moral, Mónica, García-López Durán, Juan de Dios, Luque González, Angélica, Díaz-Mochón, Juan J, Contreras-Montoya, Rafael, Martínez-Peragón, Ángela, Cuerva, Juan M, Álvarez de Cienfuegos, Luis

“…For the first time the influence of the chirality of the gel fibers in protein crystallogenesis has been studied. Enantiomeric hydrogels 1 and 2 were tested…”
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DNA Analysis by Dynamic Chemistry by Bowler, Frank R, Diaz-Mochon, Juan J, Swift, Michael D, Bradley, Mark

“…Finding flaws: An enzyme‐free method of DNA analysis raises the possibility of analyzing single‐nucleotide polymorphism, indel, and abasic sites using mass…”
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