Search Results - "Díaz, Ruth Ramos"

Assessment of exposure-response relationship for bevacizumab in patients with metastatic colorectal cancer by Peña-Cabia, Silvia, Royuela Vicente, Ana, Ramos Díaz, Ruth, Gutiérrez Nicolás, Fernando, Peñalver Vera, Ángela, Siso García, Isabel, Hitt Sabag, Ricardo, García Lacalle, Concepción, Peña-Cabia, Ana, Iglesias-Peinado, Irene, García Díaz, Benito, López-Martín, Ana

“…Limited literature is available for bevacizumab exposure-response relationship and there is not a concentration threshold associated with an optimal disease…”
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Imatinib plasma levels in patients with chronic myeloid leukaemia under routine clinical practice conditions by Del Rosario García, Betel, González García, Iris, Viña Romero, María Micaela, González García, Jonathan, Ramos Díaz, Ruth, Mourani Padrón, Ivette, Lakhwani Lakhwani, Sunil, Nazco Casariego, Gloria Julia, Gutiérrez Nicolás, Fernando

“…Introduction The addition of imatinib to the therapeutic arsenal for chronic myeloid leukaemia (CML) has changed the natural course of the disease, in such a…”
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Real-time PCR detection of PIS and PIZ alleles of SERPINA1 gene using SYBR green by Ramos-Díaz, Ruth, Escuela-Escobar, Ainhoa, Díaz-Usera, Ana, Hernández Pérez, José María, González-Carracedo, Mario Andrés, Pérez-Pérez, José Antonio

“…•Alpha-1 antitrypsin deficiency (AATD) remains underdiagnosed.•AATD is mainly caused by PI*Z and PI*S alleles of the SERPINA1 gene.•A novel genotyping test for…”
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Pharmacokinetics of Trastuzumab After Subcutaneous and Intravenous Administration in Obese Patients by González García, Jonathan, Gutiérrez Nicolás, Fernando, Ramos Díaz, Ruth, Nazco Casariego, Gloria Julia, Viña Romero, María Micaela, Llabres Martinez, Matías, Llanos Muñoz, Marta, Batista López, José Norberto, Jiménez Sosa, Alejandro, Ceballos Lenza, Isaac, Cruz Jurado, Josefina

“…Background: Subcutaneous trastuzumab (T-SC) administration does not allow the historical target concentration of 20 µg/mL for efficacy to be reached, from the…”
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Identification of a new defective SERPINA1 allele (PIZla palma) encoding an alpha-1-antitrypsin with altered glycosylation pattern by Hernández-Pérez, José M., Ramos-Díaz, Ruth, Pérez, José A.

“…Alpha-1-antitrypsin (AAT) deficiency is a genetic condition that arises from mutations in the SERPINA1 gene and predisposes to develop pulmonary emphysema and,…”
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Imatinib plasma levels in patients with gastrointestinal stromal tumour under routine clinical practice conditions by Del Rosario García, Betel, Morales Barrios, José Alberto, Jurado, Josefina Cruz, Díaz, Ruth Ramos, Viña Romero, María Micaela, Padrón, Ivette Mourani, Nazco Casariego, Gloria Julia, Nicolás, Fernando Gutiérrez

“…Objectives Imatinib is the first therapeutic option for the treatment of unresectable or metastatic gastrointestinal stromal tumours. Previous studies have…”
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Patient-reported outcomes and digital literacy of patients treated in an oncology day hospital unit by del Rosario García, Betel, Morales Barrios, José Alberto, Viña Romero, María M, Ramos Díaz, Ruth, Nazco Casariego, Gloria J, Jiménez Sosa, Alejandro, Oramas Rodríguez, Juana M, Gutiérrez Nicolás, Fernando

“…Introduction Patient-reported outcomes (PROs) use, via a computer registry, allows patients to report their symptoms enabling the detection of early signs of…”
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Validation of a fast and low-cost alkaline lysis method for gDNA extraction in a pharmacogenetic context by Ramos-Díaz, Ruth, Gutiérrez-Nicolás, Fernando, Nazco-Casariego, Gloria J, González-Perera, Itamar, Pérez-Pérez, José A

“…Purpose Translation of pharmacogenetic findings from the research laboratory to the clinical practice demands simple and efficient procedures. In this sense,…”
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Reducing the degree of colonisation of venous access catheters by continuous passive disinfection by Gutiérrez Nicolás, Fernando, Nazco Casariego, Gloria Julia, Viña Romero, María Micaela, González García, Jonathan, Ramos Diaz, Ruth, Perez Perez, Jose Antonio

“…IntroductionThe advent of Luer-type needleless venous access catheters has been accompanied by a growing number of catheter-related bloodstream infections. Our…”
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Influence of Anthropometric Characteristics in Patients With Her2-Positive Breast Cancer on Initial Plasma Concentrations of Trastuzumab by González García, Jonathan, Gutiérrez Nicolás, Fernando, Nazco Casariego, Gloria Julia, Batista López, José Norberto, Ceballos Lenza, Isaac, Ramos Díaz, Ruth, Llabrés Martínez, Matías

“…Background: Plasma concentrations of trastuzumab <20 µg/mL in patients with gastric cancer are associated with reduced progression-free and overall survival…”
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Anti-drug antibodies anti-trastuzumab in the treatment of breast cancer by Padrón, Ivette Mourani, García, Jonathan González, Díaz, Ruth Ramos, Lenza, Isaac Ceballos, Nicolás, Fernando Gutiérrez

“…Introduction Trastuzumab is a monoclonal antibody which could induce the activation of a humoral immune response generating anti-drug antibodies (ADAs). Such…”
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Extended enzymatic stability of reconstituted lyophilized PEG-asparaginase in vials by Viña-Romero, María M, Ramos Díaz, Ruth, González García, Jónathan, Nazco-Casariego, Gloria, Díaz-Vera, Jésica, Gutiérrez-Nicolás, Fernando

“…Asparaginase (ASNase) use as a tumour-inhibitor drug has changed completely the natural course of paediatric acute lymphoblastic leukaemia (ALL) in such a way…”
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Allelic Frequency of DPYD Genetic Variants in Patients With Cancer in Spain: The PhotoDPYD Study by Miarons, Marta, Manzaneque Gordón, Alba, Riera, Pau, Gutiérrez Nicolás, Fernando

“…Abstract Introduction Identifying polymorphisms in the dihydropyrimidine dehydrogenase (DPYD) gene is gaining importance to be able to predict…”
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5-fluorouracil toxicity in the treatment of colon cancer associated with the genetic polymorphism 2846 A>G (rs67376798) by González-Perera, Itamar, Gutiérrez-Nicolás, Fernando, Nazco-Casariego, Gloria J, Ramos-Díaz, Ruth, Hernández-San Gil, Raquel, Pérez-Pérez, José A, González García, Jonathan, González De La Fuente, Guillermo A

“…Colorectal cancer is the second most common cancer in Europe. Most antineoplastic regimens in first-line treatment involve 5-fluorouracil or oral prodrug…”
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Effect of UGT, SLCO, ABCB and ABCC polymorphisms on irinotecan toxicity by García Gil, Sara, Ramos Díaz, Ruth, Nazco Casariego, Gloria Julia, Llanos Muñoz, Marta, Viña Romero, Maria Micaela, Martín Calero, Braulio, Pérez Pérez, Jose Antonio, Gutiérrez Nicolás, Fernando

“…Evaluate the relationship between the presence of polymorphisms in genes involved in the pharmacodynamics of irinotecan (UGT1A, SLCO1B1, ABCB1 and ABCC2) and…”
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Description of alpha-1-antitrypsin deficiency associated with PIQ0ourém allele in La Palma Island (Spain) and a genotyping assay for its detection by Hernández Pérez, José María, Ramos Díaz, Ruth, Fumero García, Sergio, Pérez Pérez, José Antonio

“…By analysis of a case of discrepancy between serum alpha-1-antitrypsin (AAT) level and genotype for the most common defective alleles associated with AAT…”
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Description of Alpha-1-Antitrypsin Deficiency Associated With PIQ0ourém Allele in La Palma Island (Spain) and a Genotyping Assay for Detection by Hernández Pérez, José María, Ramos Díaz, Ruth, Fumero García, Sergio, Pérez Pérez, José Antonio

“…By analysis of a case of discrepancy between serum alpha-1-antitrypsin (AAT) level and genotype for the most common defective alleles associated with AAT…”
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Description of Alpha-1-Antitrypsin Deficiency Associated With PIQ0 ourém Allele in La Palma Island (Spain) and a Genotyping Assay for Detection by Hernández Pérez, José María, Ramos Díaz, Ruth, Fumero García, Sergio, Pérez Pérez, José Antonio

“…Abstract By analysis of a case of discrepancy between serum alpha-1-antitrypsin (AAT) level and genotype for the most common defective alleles associated with…”
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Descripción de la deficiencia de alfa-1-antitripsina asociada al alelo PIQ0ourém en la isla de La Palma (España) y de un método de genotipado para su detección by Hernández Pérez, José María, Ramos Díaz, Ruth, Fumero García, Sergio, Pérez Pérez, José Antonio

“…Mediante el análisis de un caso de discordancia entre el nivel de alfa-1-antitripsina (AAT) en suero y el genotipo para los alelos deficientes más…”
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Assessment of exposure-response relationship for cetuximab in patients with metastatic colorectal cancer and head and neck cancer by Peña-Cabia, Silvia, Royuela-Vicente, Ana, Ramos-Díaz, Ruth, Gutiérrez-Nicolás, Fernando, García-Díaz, Benito, López-Martín, Ana

“…There is limited scientific evidence on the cetuximab exposure-response relationship and no concentration threshold has been associated with optimal disease…”
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