Search Results - "Dávila Saldaña, Blachy J"

Experience with a Reduced Toxicity Allogeneic Transplant Regimen for Non-CGD Primary Immune Deficiencies Requiring Myeloablation by Chandra, Sharat, Chandrakasan, Shanmuganathan, Dávila Saldaña, Blachy J., Bleesing, Jack J., Jordan, Michael B., Kumar, Ashish R., Grimley, Michael S., Krupski, Christa, Davies, Stella M., Khandelwal, Pooja, Marsh, Rebecca A.

“…Purpose A need exists for reduced toxicity conditioning regimens that offer less toxicity while maintaining myeloablation, especially for primary immune…”
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Risk Factors for Symptomatic Pericardial Effusions Posthematopoietic Stem Cell Transplant by Lyons, Kelly, Dham, Niti, Schwartz, Bryanna, Dávila Saldaña, Blachy J.

“…Background. Pericardial effusions are a known complication posthematopoietic stem cell transplant (HSCT), causing significant morbidity. We aimed to evaluate…”
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Thymic Epithelial Cell Alterations and Defective Thymopoiesis Lead to Central and Peripheral Tolerance Perturbation in MHCII Deficiency by Ferrua, Francesca, Bortolomai, Ileana, Fontana, Elena, Di Silvestre, Dario, Rigoni, Rosita, Marcovecchio, Genni Enza, Draghici, Elena, Brambilla, Francesca, Castiello, Maria Carmina, Delfanti, Gloria, Moshous, Despina, Picard, Capucine, Taghon, Tom, Bordon, Victoria, Schulz, Ansgar S, Schuetz, Catharina, Giliani, Silvia, Soresina, Annarosa, Gennery, Andrew R, Signa, Sara, Dávila Saldaña, Blachy J, Delmonte, Ottavia M, Notarangelo, Luigi D, Roifman, Chaim M, Poliani, Pietro Luigi, Uva, Paolo, Mauri, Pier Luigi, Villa, Anna, Bosticardo, Marita

“…Major Histocompatibility Complex (MHC) class II (MHCII) deficiency (MHCII-D), also known as Bare Lymphocyte Syndrome (BLS), is a rare combined immunodeficiency…”
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Hospital survival following pediatric HSCT: changes in complications, ICU therapies and outcomes over 10 years by Olson, Taylor L, Pollack, Murray M, Dávila Saldaña, Blachy J, Patel, Anita K

“…Hematopoietic stem cell transplantation (HSCT) is an increasingly utilized therapy for malignant and non-malignant pediatric diseases. HSCT complications,…”
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Pediatric lymphoproliferative disorders associated with inborn errors of immunity by Cheng, Jinjun, Dávila Saldaña, Blachy J., Chandrakasan, Shanmuganathan, Keller, Michael

“…Both non-malignant and malignant lymphoproliferative disorders (LPD) are commonly seen in patients with inborn errors of immunity (IEI), which may be the…”
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High risk of relapsed disease in patients with NK/T-cell chronic active Epstein-Barr virus disease outside of Asia by Dávila Saldaña, Blachy J., John, Tami, Bonifant, Challice, Buchbinder, David, Chandra, Sharat, Chandrakasan, Shanmuganathan, Chang, Weni, Chen, Leon, Elfassy, Hannah L., Geerlinks, Ashley V., Giller, Roger H., Goyal, Rakesh, Hagin, David, Islam, Shahidul, Mallhi, Kanwaldeep, Miller, Holly K., Owen, William, Pacheco, Martha, Patel, Niraj C., Querfeld, Christiane, Quigg, Troy, Richard, Nameeta, Schiff, Deborah, Shereck, Evan, Stenger, Elizabeth, Jordan, Michael B., Heslop, Helen E., Bollard, Catherine M., Cohen, Jeffrey I.

“…Chronic active Epstein-Barr virus (EBV) disease (CAEBV) is characterized by high levels of EBV predominantly in T and/or natural killer cells with…”
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Activated phosphoinositide 3-kinase δ syndrome in a patient with a former diagnosis of common variable immune deficiency, bronchiectasis, and lymphoproliferative disease by Kannan, Jennifer A., MD, Dávila-Saldaña, Blachy J., MD, Zhang, Kejian, MD, Filipovich, Alexandra H., MD, Kucuk, Zeynep Yesim, MD

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The genetic landscape of severe combined immunodeficiency in the United States and Canada in the current era (2010-2018) by Dvorak, Christopher C., Haddad, Elie, Buckley, Rebecca H., Cowan, Morton J., Logan, Brent, Griffith, Linda M., Kohn, Donald B., Pai, Sung-Yun, Notarangelo, Luigi, Shearer, William, Prockop, Susan, Kapoor, Neena, Heimall, Jennifer, Chaudhury, Sonali, Shyr, David, Chandra, Sharat, Cuvelier, Geoff, Moore, Theodore, Shenoy, Shalini, Goldman, Fred, Smith, Angela R., Sunkersett, Gauri, Vander Lugt, Mark, Caywood, Emi, Quigg, Troy, Torgerson, Troy, Chandrakasan, Shanmuganathan, Craddock, John, Dávila Saldaña, Blachy J., Gillio, Alfred, Shereck, Evan, Aquino, Victor, DeSantes, Kenneth, Knutsen, Alan, Thakar, Monica, Yu, Lolie, Puck, Jennifer M.

“…To the Editor: There has been increased appreciation in recent years that severe combined immunodeficiency (SCID) is not one disease, but rather a collection…”
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HSCT for PID: not just for children by Dávila Saldaña, Blachy J.

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Poor T-cell receptor β repertoire diversity early posttransplant for severe combined immunodeficiency predicts failure of immune reconstitution by Delmonte, Ottavia M., Castagnoli, Riccardo, Yu, Jason, Dvorak, Christopher C., Cowan, Morton J., Dávila Saldaña, Blachy J., De Ravin, Suk See, Mamcarz, Ewelina, Chang, Catherine K., Daley, Stephen R., Griffith, Linda M., Notarangelo, Luigi D., Puck, Jennifer M.

“…Development of a diverse T-cell receptor β (TRB) repertoire is associated with immune recovery following hematopoietic cell transplantation (HCT) for severe…”
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Allogeneic hematopoietic cell transplantation is effective for p47phox chronic granulomatous disease: A  Primary Immune Deficiency Treatment Consortium study by Grunebaum, Eyal, Arnold, Danielle E., Logan, Brent, Parikh, Suhag, Marsh, Rebecca A., Griffith, Linda M., Mallhi, Kanwaldeep, Chellapandian, Deepak, Lim, Stephanie Si, Deal, Christin L., Kapoor, Neena, Murguía-Favela, Luis, Falcone, Emilia Liana, Prasad, Vinod K., Touzot, Fabien, Bleesing, Jack J., Chandrakasan, Shanmuganathan, Heimall, Jennifer R., Bednarski, Jeffrey J., Broglie, Larisa A., Chong, Hey Jin, Kapadia, Malika, Prockop, Susan, Dávila Saldaña, Blachy J., Schaefer, Edo, Bauchat, Andrea L., Teira, Pierre, Chandra, Sharat, Parta, Mark, Cowan, Morton J., Dvorak, Christopher C., Haddad, Elie, Kohn, Donald B., Notarangelo, Luigi D., Pai, Sung-Yun, Puck, Jennifer M., Pulsipher, Michael A., Torgerson, Troy R., Malech, Harry L., Kang, Elizabeth M., Leiding, Jennifer W.

“…P47phox (neutrophil cytosolic factor-1) deficiency is the most common cause of autosomal recessive chronic granulomatous disease (CGD) and is considered to be…”
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Tap water: A possible source of nontuberculous mycobacterial infection in patients with T cell deficiency by Dávila Saldaña, Blachy J., Keller, Michael, Hanisch, Benjamin R., Song, Xiaoyan

“…•Nontuberculous mycobacteria are an infectious threat to patients with lymphopenia.•Tap water is a potential source of infection, both in the community and the…”
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Primary Immunodeficiencies and Hematologic Malignancies: A Diagnostic Approach by Chandra, Sharat, Kalashnikova, Tatiana, Wright, Nicola A M, Dávila Saldaña, Blachy J

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B-cell differentiation and IL-21 response in IL2RG/JAK3 SCID patients after hematopoietic stem cell transplantation by Miggelbrink, Alexandra M., Logan, Brent R., Buckley, Rebecca H., Parrott, Roberta E., Dvorak, Christopher C., Kapoor, Neena, Abdel-Azim, Hisham, Prockop, Susan E., Shyr, David, Decaluwe, Hélène, Hanson, Imelda C., Gillio, Alfred, Dávila Saldaña, Blachy J., Eibel, Hermann, Hopkins, Gregory, Walter, Jolan E., Whangbo, Jennifer S., Kohn, Donald B., Puck, Jennifer M., Cowan, Morton J., Griffith, Linda M., Haddad, Elie, O'Reilly, Richard J., Notarangelo, Luigi D., Pai, Sung-Yun

“…Allogeneic hematopoietic stem cell transplant (HSCT) typically results in donor T-cell engraftment and function in patients with severe combined…”
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Haploidentical bone marrow transplantation in patients with relapsed or refractory severe aplastic anaemia in the USA (BMT CTN 1502): a multicentre, single-arm, phase 2 trial by DeZern, Amy E, Eapen, Mary, Wu, Juan, Talano, Julie-An, Solh, Melhem, Dávila Saldaña, Blachy J, Karanes, Chatchada, Horwitz, Mitchell E, Mallhi, Kanwaldeep, Arai, Sally, Farhadfar, Nosha, Hexner, Elizabeth, Westervelt, Peter, Antin, Joseph H, Deeg, H Joachim, Leifer, Eric, Brodsky, Robert A, Logan, Brent R, Horowitz, Mary M, Jones, Richard J, Pulsipher, Michael A

“…Relapsed severe aplastic anaemia is a marrow failure disorder with high morbidity and mortality. It is often treated with bone marrow transplantation at…”
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Aberrant T-cell exhaustion in severe combined immunodeficiency survivors with poor T-cell reconstitution after transplantation by Labrosse, Roxane, Boufaied, Ines, Bourdin, Benoîte, Gona, Saideep, Randolph, Haley E., Logan, Brent R., Bourbonnais, Sara, Berthe, Chloé, Chan, Wendy, Buckley, Rebecca H., Parrott, Roberta E., Cuvelier, Geoffrey D.E., Kapoor, Neena, Chandra, Sharat, Dávila Saldaña, Blachy J., Eissa, Hesham, Goldman, Fred D., Heimall, Jennifer, O’Reilly, Richard, Chaudhury, Sonali, Kolb, Edward A., Shenoy, Shalini, Griffith, Linda M., Pulsipher, Michael, Kohn, Donald B., Notarangelo, Luigi D., Pai, Sung-Yun, Cowan, Morton J., Dvorak, Christopher C., Haddad, Élie, Puck, Jennifer M., Barreiro, Luis B., Decaluwe, Hélène

“…Severe combined immunodeficiency (SCID) comprises rare inherited disorders of immunity that require definitive treatment through hematopoietic cell…”
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SCID genotype and 6-month posttransplant CD4 count predict survival and immune recovery by Haddad, Elie, Logan, Brent R., Griffith, Linda M., Buckley, Rebecca H., Parrott, Roberta E., Prockop, Susan E., Small, Trudy N., Chaisson, Jessica, Dvorak, Christopher C., Murnane, Megan, Kapoor, Neena, Abdel-Azim, Hisham, Hanson, Imelda C., Martinez, Caridad, Bleesing, Jack J.H., Chandra, Sharat, Smith, Angela R., Cavanaugh, Matthew E., Jyonouchi, Soma, Sullivan, Kathleen E., Burroughs, Lauri, Skoda-Smith, Suzanne, Haight, Ann E., Tumlin, Audrey G., Quigg, Troy C., Taylor, Candace, Dávila Saldaña, Blachy J., Keller, Michael D., Seroogy, Christine M., Desantes, Kenneth B., Petrovic, Aleksandra, Leiding, Jennifer W., Shyr, David C., Decaluwe, Hélène, Teira, Pierre, Gillio, Alfred P., Knutsen, Alan P., Moore, Theodore B., Kletzel, Morris, Craddock, John A., Aquino, Victor, Davis, Jeffrey H., Yu, Lolie C., Cuvelier, Geoffrey D.E., Bednarski, Jeffrey J., Goldman, Frederick D., Kang, Elizabeth M., Shereck, Evan, Porteus, Matthew H., Connelly, James A., Fleisher, Thomas A., Malech, Harry L., Shearer, William T., Szabolcs, Paul, Thakar, Monica S., Vander Lugt, Mark T., Heimall, Jennifer, Yin, Ziyan, Pulsipher, Michael A., Pai, Sung-Yun, Kohn, Donald B., Puck, Jennifer M., Cowan, Morton J., O'Reilly, Richard J., Notarangelo, Luigi D.

“…The Primary Immune Deficiency Treatment Consortium (PIDTC) performed a retrospective analysis of 662 patients with severe combined immunodeficiency (SCID) who…”
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Excellent outcomes following hematopoietic cell transplantation for Wiskott-Aldrich syndrome: a PIDTC report by Burroughs, Lauri M., Petrovic, Aleksandra, Brazauskas, Ruta, Liu, Xuerong, Griffith, Linda M., Ochs, Hans D., Bleesing, Jack J., Edwards, Stephanie, Dvorak, Christopher C., Chaudhury, Sonali, Prockop, Susan E., Quinones, Ralph, Goldman, Frederick D., Quigg, Troy C., Chandrakasan, Shanmuganathan, Smith, Angela R., Parikh, Suhag, Dávila Saldaña, Blachy J., Thakar, Monica S., Phelan, Rachel, Shenoy, Shalini, Forbes, Lisa R., Martinez, Caridad, Chellapandian, Deepak, Shereck, Evan, Miller, Holly K., Kapoor, Neena, Barnum, Jessie L., Chong, Hey, Shyr, David C., Chen, Karin, Abu-Arja, Rolla, Shah, Ami J., Weinacht, Katja G., Moore, Theodore B., Joshi, Avni, DeSantes, Kenneth B., Gillio, Alfred P., Cuvelier, Geoffrey D.E., Keller, Michael D., Rozmus, Jacob, Torgerson, Troy, Pulsipher, Michael A., Haddad, Elie, Sullivan, Kathleen E., Logan, Brent R., Kohn, Donald B., Puck, Jennifer M., Notarangelo, Luigi D., Pai, Sung-Yun, Rawlings, David J., Cowan, Morton J.

“…Wiskott-Aldrich syndrome (WAS) is an X-linked disease caused by mutations in the WAS gene, leading to thrombocytopenia, eczema, recurrent infections,…”
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Antiviral cellular therapy for enhancing T-cell reconstitution before or after hematopoietic stem cell transplantation (ACES): a two-arm, open label phase II interventional trial of pediatric patients with risk factor assessment by Keller, Michael D., Hanley, Patrick J., Chi, Yueh-Yun, Aguayo-Hiraldo, Paibel, Dvorak, Christopher C., Verneris, Michael R., Kohn, Donald B., Pai, Sung-Yun, Dávila Saldaña, Blachy J., Hanisch, Benjamin, Quigg, Troy C., Adams, Roberta H., Dahlberg, Ann, Chandrakasan, Shanmuganathan, Hasan, Hasibul, Malvar, Jemily, Jensen-Wachspress, Mariah A., Lazarski, Christopher A., Sani, Gelina, Idso, John M., Lang, Haili, Chansky, Pamela, McCann, Chase D., Tanna, Jay, Abraham, Allistair A., Webb, Jennifer L., Shibli, Abeer, Keating, Amy K., Satwani, Prakash, Muranski, Pawel, Hall, Erin, Eckrich, Michael J., Shereck, Evan, Miller, Holly, Mamcarz, Ewelina, Agarwal, Rajni, De Oliveira, Satiro N., Vander Lugt, Mark T., Ebens, Christen L., Aquino, Victor M., Bednarski, Jeffrey J., Chu, Julia, Parikh, Suhag, Whangbo, Jennifer, Lionakis, Michail, Zambidis, Elias T., Gourdine, Elizabeth, Bollard, Catherine M., Pulsipher, Michael A.

“…Viral infections remain a major risk in immunocompromised pediatric patients, and virus-specific T cell (VST) therapy has been successful for treatment of…”
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Relevance of lymphocyte proliferation to PHA in severe combined immunodeficiency (SCID) and T cell lymphopenia by Abraham, Roshini S., Basu, Amrita, Heimall, Jennifer R., Dunn, Elizabeth, Yip, Alison, Kapadia, Malika, Kapoor, Neena, Satter, Lisa Forbes, Buckley, Rebecca, O'Reilly, Richard, Cuvelier, Geoffrey D.E., Chandra, Sharat, Bednarski, Jeffrey, Chaudhury, Sonali, Moore, Theodore B., Haines, Hilary, Dávila Saldaña, Blachy J., Chellapandian, Deepakbabu, Rayes, Ahmad, Chen, Karin, Caywood, Emi, Chandrakasan, Shanmuganathan, Lugt, Mark Thomas Vander, Ebens, Christen, Teira, Pierre, Shereck, Evan, Miller, Holly, Aquino, Victor, Eissa, Hesham, Yu, Lolie C., Gillio, Alfred, Madden, Lisa, Knutsen, Alan, Shah, Ami J., DeSantes, Kenneth, Barnum, Jessie, Broglie, Larisa, Joshi, Avni Y., Kleiner, Gary, Dara, Jasmeen, Prockop, Susan, Martinez, Caridad, Mousallem, Talal, Oved, Joseph, Burroughs, Lauri, Marsh, Rebecca, Torgerson, Troy R., Leiding, Jennifer W., Pai, Sung Yun, Kohn, Donald B., Pulsipher, Michael A., Griffith, Linda M., Notarangelo, Luigi D., Cowan, Morton J., Puck, Jennifer, Dvorak, Christopher C., Haddad, Elie

“…Severe combined immunodeficiency (SCID) is characterized by a severe deficiency in T cell numbers. We analyzed data collected (n = 307) for PHA-based T cell…”
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