Search Results - "D, Sharan"
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DNA methylation analysis of the autistic brain reveals multiple dysregulated biological pathways
Published in Translational psychiatry (02-09-2014)“…Autism spectrum disorders (ASD) are a group of neurodevelopmental conditions characterized by dysfunction in social interaction, communication and stereotypic…”
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Laser interstitial thermal therapy for medically intractable mesial temporal lobe epilepsy
Published in Epilepsia (Copenhagen) (01-02-2016)“…Summary Objective To describe mesial temporal lobe ablated volumes, verbal memory, and surgical outcomes in patients with medically intractable mesial temporal…”
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Direct recordings of grid-like neuronal activity in human spatial navigation
Published in Nature neuroscience (01-09-2013)“…Grid cell activity in the rodent and non-human primate entorhinal cortex is thought to provide spatial location information to the hippocampus for navigation…”
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Closed-loop stimulation of temporal cortex rescues functional networks and improves memory
Published in Nature communications (06-02-2018)“…Memory failures are frustrating and often the result of ineffective encoding. One approach to improving memory outcomes is through direct modulation of brain…”
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Synchronous and asynchronous theta and gamma activity during episodic memory formation
Published in The Journal of neuroscience (02-01-2013)“…To test the hypothesis that neural oscillations synchronize to mediate memory encoding, we analyzed electrocorticographic recordings taken as 68 human…”
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Contribution of left supramarginal and angular gyri to episodic memory encoding: An intracranial EEG study
Published in NeuroImage (Orlando, Fla.) (15-01-2021)“…The role of the left ventral lateral parietal cortex (VPC) in episodic memory is hypothesized to include bottom-up attentional orienting to recalled items,…”
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Human intracranial high-frequency activity maps episodic memory formation in space and time
Published in NeuroImage (Orlando, Fla.) (15-01-2014)“…Noninvasive neuroimaging studies have revealed a network of brain regions that activate during human memory encoding; however, the relative timing of such…”
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Safety and efficacy of peripheral nerve stimulation of the occipital nerves for the management of chronic migraine: long-term results from a randomized, multicenter, double-blinded, controlled study
Published in Cephalalgia (01-04-2015)“…Recent studies evaluated short-term efficacy and safety of peripheral nerve stimulation (PNS) of the occipital nerves for managing chronic migraine. We present…”
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Reactivated Spatial Context Guides Episodic Recall
Published in The Journal of neuroscience (04-03-2020)“…The medial temporal lobe (MTL) is known as the locus of spatial coding and episodic memory, but the interaction between these cognitive domains as well as the…”
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Complications of subdural and depth electrodes in 269 patients undergoing 317 procedures for invasive monitoring in epilepsy
Published in Epilepsia (Copenhagen) (01-10-2016)“…Summary Objective Intracranial monitoring is fundamental to epilepsy surgery, with reported complication rates of 3–17%. We aimed to assess the differences in…”
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Patient Positioning in Spine Surgery: What Spine Surgeons Should Know?
Published in Asian spine journal (01-08-2023)“…Spine surgery has advanced tremendously over the last decade. The number of spine surgeries performed each year has also been increasing constantly…”
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Interictal epileptiform discharges impair word recall in multiple brain areas
Published in Epilepsia (Copenhagen) (01-03-2017)“…Summary Objectives Interictal epileptiform discharges (IEDs) have been linked to memory impairment, but the spatial and temporal dynamics of this relationship…”
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Theta-burst stimulation entrains frequency-specific oscillatory responses
Published in Brain stimulation (01-09-2021)“…Brain stimulation has emerged as a powerful tool in human neuroscience, becoming integral to next-generation psychiatric and neurologic therapeutics…”
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Long-Term Measurement of Impedance in Chronically Implanted Depth and Subdural Electrodes During Responsive Neurostimulation in Humans
Published in Brain stimulation (01-09-2013)“…Abstract Long-term stability of the electrode–tissue interface may be required to maintain optimal neural recording with subdural and deep brain implants and…”
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Deep brain stimulation for Parkinson's disease: Surgical technique and perioperative management
Published in Movement disorders (01-06-2006)“…Deep brain stimulation (DBS) is a widely accepted therapy for medically refractory Parkinson's disease (PD). Both globus pallidus internus (GPi) and…”
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Neurostimulation for the treatment of epilepsy: a review of current surgical interventions
Published in Neuromodulation (Malden, Mass.) (01-01-2013)“…Epilepsy continues to provide challenges to clinicians, as a significant proportion of patients continue to suffer from seizures despite medical and surgical…”
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Patient Comorbidities and Complications After Spinal Surgery: A Societal-Based Cost Analysis
Published in Spine (Philadelphia, Pa. 1976) (20-05-2012)“…Prospective observational study. To determine how patient comorbidities and perioperative complications after spinal surgery affect the health care costs to…”
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Association of Opioid Usage with Spinal Cord Stimulation Outcomes
Published in Pain medicine (Malden, Mass.) (01-04-2018)“…Abstract Study Design Observational study using insurance claims. Objective To quantify opioid usage leading up to spinal cord stimulation (SCS) and the…”
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Thirdhand smoke causes DNA damage in human cells
Published in Mutagenesis (01-07-2013)“…Exposure to thirdhand smoke (THS) is a newly described health risk. Evidence supports its widespread presence in indoor environments. However, its genotoxic…”
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