Search Results - "D, Lofrumento"

An aqueous olive leaf extract (OLE) ameliorates parameters of oxidative stress associated with lipid accumulation and induces lipophagy in human hepatic cells by S, Tacconi, S, Longo, F, Guerra, C, Moliteni, M, Friuli, A, Romano, S, Gaetani, V M, Paradiso, G, Difonzo, F, Caponio, D, Lofrumento, D, Vergara, C, Bucci, L, Dini, A M, Giudetti

“…Fatty liver is a disease characterized by a buildup of lipids in the liver, often resulting from excessive consumption of high-fat-containing foods. Fatty…”
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Downstream activation of NF‐κB in the EDA‐A1/EDAR signalling in Sjögren's syndrome and its regulation by the ubiquitin‐editing enzyme A20 by Sisto, M., Barca, A., Lofrumento, D. D., Lisi, S.

“…Summary Sjögren's syndrome (SS) is an autoimmune disease and the second most common chronic systemic rheumatic disorder. Prevalence of primary SS in the…”
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Uterine Wound Healing: A Complex Process Mediated by Proteins and Peptides by Lofrumento, Dario D, Di Nardo, Maria A, De Falco, Marianna, Di Lieto, Andrea

“…Wound healing is the process by which a complex cascade of biochemical events is responsible of the repair the damage. In vivo, studies in humans and mice…”
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Downstream activation of NF-[kappa]B in the EDA-A1/EDAR signalling in Sjögren's syndrome and its regulation by the ubiquitin-editing enzyme A20 by Sisto, M, Barca, A, Lofrumento, D D, Lisi, S

“…Summary Sjögren's syndrome (SS) is an autoimmune disease and the second most common chronic systemic rheumatic disorder. Prevalence of primary SS in the…”
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Increased hexosamine biosynthetic pathway flux dedifferentiates INS-1E cells and murine islets by an extracellular signal-regulated kinase (ERK)1/2-mediated signal transmission pathway by Lombardi, A., Ulianich, L., Treglia, A. S., Nigro, C., Parrillo, L., Lofrumento, D. D., Nicolardi, G., Garbi, C., Beguinot, F., Miele, C., Di Jeso, B.

“…Aims/hypothesis Beta cell failure is caused by loss of cell mass, mostly by apoptosis, but also by simple dysfunction (decline of glucose-stimulated insulin…”
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Sjögren’s syndrome pathological neovascularization is regulated by VEGF-A-stimulated TACE-dependent crosstalk between VEGFR2 and NF-κB by Sisto, M, Lisi, S, Lofrumento, D D, D'Amore, M, Frassanito, M A, Ribatti, D

“…We explore the involvement of tumor necrosis factor α (TNF-α)-converting enzyme (TACE) in vascular endothelial growth factor (VEGF) and its receptor 2 (VEGFR2)…”
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Neuroprotective effects of resveratrol in an MPTP mouse model of Parkinson's-like disease: possible role of SOCS-1 in reducing pro-inflammatory responses by Lofrumento, Dario D, Nicolardi, Giuseppe, Cianciulli, Antonia, De Nuccio, Francesco, La Pesa, Velia, Carofiglio, Vito, Dragone, Teresa, Calvello, Rosa, Panaro, Maria A

“…In the present study we used a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced Parkinson's disease (PD) mouse model to analyze resveratrol…”
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Rituximab‐mediated Raf kinase inhibitor protein induction modulates NF‐κB in Sjögren syndrome by Sisto, Margherita, Lisi, Sabrina, D'Amore, Massimo, Lofrumento, Dario D.

“…Summary Primary Sjögren syndrome (pSS) is an autoimmune disorder characterized by an epithelial injury surrounded by dense lymphocytic infiltrates. The…”
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Nitric oxide production by macrophages of dogs vaccinated with killed Leishmania infantum promastigotes by Panaro, M.A., Acquafredda, A., Lisi, S., Lofrumento, D.D., Mitolo, V., Sisto, M., Fasanella, A., Trotta, T., Bertani, F., Consenti, B., Brandonisio, O.

“…Human visceral leishmaniosis is endemic in Southern Italy, where the dog is the main reservoir of viscerotropic strains of Leishmania infantum. The release of…”
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Transient Covalent Interactions of Newly Synthesized Thyroglobulin with Oxidoreductases of the Endoplasmic Reticulum by Di Jeso, Bruno, Morishita, Yoshiaki, Treglia, Antonella S., Lofrumento, Dario D., Nicolardi, Giuseppe, Beguinot, Francesco, Kellogg, Aaron P., Arvan, Peter

“…Newly synthesized thyroglobulin (Tg), the thyroid prohormone, forms detectable high molecular weight mixed disulfide adducts: until now, only Tg “adduct B” was…”
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Saponins from Tribulus terrestris L. protect human keratinocytes from UVB-induced damage by Sisto, Margherita, Lisi, Sabrina, D’Amore, Massimo, Lucro, Raffaella De, Carati, Davide, Castellana, Donatello, Pesa, Velia La, Zuccarello, Vincenzo, Lofrumento, Dario D.

“…► The photoprotective role of Tribulus terrestris L. was studied upon UVB irradiation. ► In squamous cell carcinomas Tribulus determine an enhanced apoptotic…”
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TNF blocker drugs modulate human TNF-α-converting enzyme pro-domain shedding induced by autoantibodies by Sisto, Margherita, Lisi, Sabrina, Lofrumento, Dario D, Caprio, Simone, Mitolo, Vincenzo, D’Amore, Massimo

“…Abstract Novel biologic therapies targeted against specific components of the immune system, including blockade of TNF-α have revolutionized therapeutic…”
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Sjogren's syndrome pathological neovascularization is regulated by VEGF-A-stimulated TACE-dependent crosstalk between VEGFR2 and NF-[kappa]B by Sisto, M, Lisi, S, Lofrumento, D D, D'amore, M, Frassanito, M A, Ribatti, D

“…We explore the involvement of tumor necrosis factor α (TNF-α)-converting enzyme (TACE) in vascular endothelial growth factor (VEGF) and its receptor 2 (VEGFR2)…”
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Cell fate following ER stress: just a matter of "quo ante" recovery or death? by Treglia, A S, Turco, S, Ulianich, L, Ausiello, P, Lofrumento, D D, Nicolardi, G, Miele, C, Garbi, C, Beguinot, F, Di Jeso, B

“…The endoplasmic reticulum (ER) is a complex and multifunctional organelle. It is the intracellular compartment of protein folding, a complex task, both…”
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Inducible nitric oxide synthase and nitric oxide production in Leishmania infantum-infected human macrophages stimulated with interferon-γ and bacterial lipopolysaccharide by PANARO, M. A, ACQUAFREDDA, A, LISI, S, LOFRUMENTO, D. D, TROTTA, T, SATALINO, R, SACCIA, M, MITOLO, V, BRANDONISIO, O

“…Nitric oxide produced by an inducible nitric oxide synthase constitutes one of the main microbicidal mechanisms of murine macrophages and its importance is now…”
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Expression of TLR4 and CD14 in the Central Nervous System (CNS) in a MPTP Mouse Model of Parkinson's-Like Disease by Panaro, Maria Antonietta, Lofrumento, Dario Domenico, Saponaro, Concetta, De Nuccio, Francesco, Cianciulli, Antonia, Mitolo, Vincenzo, Nicolardi, Giuseppe

“…Systemic infections are often associated with neurodegenerative processes in many diseases of the central nervous system (CNS), including Parkinson's disease…”
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Induction of TNF-alpha-converting enzyme-ectodomain shedding by pathogenic autoantibodies by Sisto, Margherita, Lisi, Sabrina, Lofrumento, Dario Domenico, Frassanito, Maria Antonia, Cucci, Liana, D'Amore, Simona, Mitolo, Vincenzo, D'Amore, Massimo

“…The release of the soluble form of tumor necrosis factor (TNF)-alpha from the plasma membrane occurs through the activation of the secretase tumor necrosis…”
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Fibulin-6 expression and anoikis in human salivary gland epithelial cells: implications in Sjogren's syndrome by Sisto, Margherita, D'Amore, Massimo, Lofrumento, Dario Domenico, Scagliusi, Pasquale, D’Amore, Simona, Mitolo, Vincenzo, Lisi, Sabrina

“…Important changes in acinar and ductal morphology and function, together with pronounced extracellular matrix (ECM) remodelling, are detectable in the labial…”
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Modulation between aerobic and anaerobic metabolism in the mutant cell line CdtR-Q by Lofrumento, D D, Panaro, M A, Mitolo, V

“…It has recently been shown that the cell line Don Q obtained by mutagenesis of wild type Chinese hamster lung fibroblasts (Don wt), presents a point mutation…”
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Rituximab-mediated Raf kinase inhibitor protein induction modulates NF-[kappa]B in Sjögren syndrome by Sisto, Margherita, Lisi, Sabrina, D'Amore, Massimo, Lofrumento, Dario D

“…Summary Primary Sjögren syndrome (pSS) is an autoimmune disorder characterized by an epithelial injury surrounded by dense lymphocytic infiltrates. The…”
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