Search Results - "D'souza, Leonard Clinton"
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Environmental toxicants, oxidative stress and health adversities: interventions of phytochemicals
Published in Journal of pharmacy and pharmacology (20-04-2022)“…Oxidative stress is the most common factor mediating environmental chemical-induced health adversities. Recently, an exponential rise in the use of…”
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Reprogramming of glycolysis by chemical carcinogens during tumor development
Published in Seminars in cancer biology (01-12-2022)“…Indiscriminate usage and mismanagement of chemicals in the agricultural and industrial sectors have contaminated different environmental compartments. Exposure…”
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Toxicity Assessment of Curculigo orchioides Leaf Extract Using Drosophila melanogaster : A Preliminary Study
Published in International journal of environmental research and public health (18-11-2022)“…is used in Indian and Chinese traditional medicinal systems for various health benefits. However, its toxicological effects are mostly unknown. This study…”
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Efficacy of Cannabis and its Constituents in Disease Management: Insights from Clinical Studies
Published in Current medicinal chemistry (2023)“…There is a long history of informal use of Cannabis sativa (commonly called cannabis) for many purposes, including treating various ailments worldwide…”
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Annexin A2 and its downstream IL-6 and HB-EGF as secretory biomarkers in the differential diagnosis of Her-2 negative breast cancer
Published in Annals of clinical biochemistry (01-07-2017)“…Background AnnexinA2 (AnxA2) membrane deposition has a critical role in HB-EGF shedding as well as IL-6 secretion in breast cancer cells. This autocrine cycle…”
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6
Role of Hematopoietic ‘Niche’ in Benzene-Induced Hematopoietic Emergency: Lesson from Drosophila
Published in Free radical biology & medicine (01-11-2023)Get full text
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Environmental Chemical-Induced Reactive Oxygen Species Generation and Immunotoxicity: A Comprehensive Review
Published in Antioxidants & redox signaling (01-04-2024)“…Reactive oxygen species (ROS), the reactive oxygen-carrying chemicals moieties, act as pleiotropic signal transducers to maintain various biological…”
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Hsp27, a potential EcR target, protects nonylphenol-induced cellular and organismal toxicity in Drosophila melanogaster
Published in Environmental pollution (1987) (15-01-2022)“…Deciphering the potential mechanism of chemical-induced toxicity enables us to alleviate the cellular and organismal dysfunction. The environmental presence of…”
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ROS-directed activation of Toll/NF-κB in the hematopoietic niche triggers benzene-induced emergency hematopoiesis
Published in Free radical biology & medicine (20-11-2022)“…Hematopoietic stem cells/progenitor cells (HSC/HPCs) orchestrate the hematopoietic process, effectively regulated by the hematopoietic niche under normal and…”
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Hsp70 overexpression in Drosophila hemocytes attenuates benzene‐induced immune and developmental toxicity via regulating ROS/JNK signaling pathway
Published in Environmental toxicology (01-07-2022)“…Benzene, a ubiquitous environmental chemical, is known to cause immune dysfunction and developmental defects. This study aims to investigate the relation…”
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