Search Results - "D'souza, Anishka"

Overview, Diagnosis, and Perioperative Systemic Therapy of Upper Tract Urothelial Carcinoma by Kolawa, Adam, D’Souza, Anishka, Tulpule, Varsha

“…Upper tract urothelial carcinoma comprises 5–10% of all urothelial carcinoma cases. This disease tends to have a more aggressive course than its lower urinary…”
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Overcoming endocrine resistance in metastatic hormone receptor-positive breast cancer by D'Souza, Anishka, Spicer, Darcy, Lu, Janice

“…Endocrine therapy has historically formed the basis of treatment of metastatic hormone receptor-positive breast cancer. The development of endocrine resistance…”
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Bladder cancer: from a therapeutic wilderness to so many options; a guide to practice in a changing landscape by D’souza, Anishka A., Tulpule, Varsha, Zang, Peter D., Quinn, David I.

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Disease characterization in liquid biopsy from HER2-mutated, non-amplified metastatic breast cancer patients treated with neratinib by Shishido, Stephanie N., Masson, Rahul, Xu, Liya, Welter, Lisa, Prabakar, Rishvanth Kaliappan, D’ Souza, Anishka, Spicer, Darcy, Kang, Irene, Jayachandran, Priya, Hicks, James, Lu, Janice, Kuhn, Peter

“…Metastatic breast cancer (mBC) patients have a high risk of progression and face poor prognosis overall, with about one third (34%) surviving five years or…”
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Comprehensive Systematic Review of Biomarkers in Metastatic Renal Cell Carcinoma: Predictors, Prognostics, and Therapeutic Monitoring by Dani, Komal A, Rich, Joseph M, Kumar, Sean S, Cen, Harmony, Duddalwar, Vinay A, D’Souza, Anishka

“…Background: Challenges remain in determining the most effective treatment strategies and identifying patients who would benefit from adjuvant or neoadjuvant…”
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Gemcitabine and cisplatin plus nivolumab as organ-sparing treatment for muscle-invasive bladder cancer: a phase 2 trial by Galsky, Matthew D., Daneshmand, Siamak, Izadmehr, Sudeh, Gonzalez-Kozlova, Edgar, Chan, Kevin G., Lewis, Sara, Achkar, Bassam El, Dorff, Tanya B., Cetnar, Jeremy Paul, Neil, Brock O., D’Souza, Anishka, Mamtani, Ronac, Kyriakopoulos, Christos, Jun, Tomi, Gogerly-Moragoda, Mahalya, Brody, Rachel, Xie, Hui, Nie, Kai, Kelly, Geoffrey, Horowitz, Amir, Kinoshita, Yayoi, Ellis, Ethan, Nose, Yohei, Ioannou, Giorgio, Cabal, Rafael, Del Valle, Diane M., Haines, G. Kenneth, Wang, Li, Mouw, Kent W., Samstein, Robert M., Mehrazin, Reza, Bhardwaj, Nina, Yu, Menggang, Zhao, Qianqian, Kim-Schulze, Seunghee, Sebra, Robert, Zhu, Jun, Gnjatic, Sacha, Sfakianos, John, Pal, Sumanta K.

“…Cystectomy is a standard treatment for muscle-invasive bladder cancer (MIBC), but it is life-altering. We initiated a phase 2 study in which patients with MIBC…”
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Neratinib in patients with HER2-mutant, metastatic cervical cancer: Findings from the phase 2 SUMMIT basket trial by Oaknin, Ana, Friedman, Claire F., Roman, Lynda D., D'Souza, Anishka, Brana, Irene, Bidard, François-Clement, Goldman, Jonathan, Alvarez, Edwin A., Boni, Valentina, ElNaggar, Adam C., Passalacqua, Rodolfo, Do, Khanh T.M., Santin, Alessandro D., Keyvanjah, Kiana, Xu, Feng, Eli, Lisa D., Lalani, Alshad S., Bryce, Richard P., Hyman, David M., Meric-Bernstam, Funda, Solit, David B., Monk, Bradley J.

“…Somatic HER2 mutations occur in ~5% of cervical cancers and are considered oncogenic and associated with poor prognosis. Neratinib, an irreversible pan-HER…”
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SETD2 Deficiency Confers Sensitivity to Dual Inhibition of DNA Methylation and PARP in Kidney Cancer by Zhou, Xinyi, Sekino, Yohei, Li, Hong-Tao, Fu, Guanghou, Yang, Zhi, Zhao, Shuqing, Gujar, Hemant, Zu, Xiongbing, Weisenberger, Daniel J, Gill, Inderbir S, Tulpule, Varsha, D'souza, Anishka, Quinn, David I, Han, Bo, Liang, Gangning

“…SETD2 deficiency alters the epigenetic landscape by causing depletion of H3K36me3 and plays an important role in diverse forms of cancer, most notably in…”
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Author Correction: Gemcitabine and cisplatin plus nivolumab as organ-sparing treatment for muscle-invasive bladder cancer: a phase 2 trial by Galsky, Matthew D., Daneshmand, Siamak, Izadmehr, Sudeh, Gonzalez-Kozlova, Edgar, Chan, Kevin G., Lewis, Sara, Achkar, Bassam El, Dorff, Tanya B., Cetnar, Jeremy Paul, Neil, Brock O., D’Souza, Anishka, Mamtani, Ronac, Kyriakopoulos, Christos, Jun, Tomi, Gogerly-Moragoda, Mahalya, Brody, Rachel, Xie, Hui, Nie, Kai, Kelly, Geoffrey, Horowitz, Amir, Kinoshita, Yayoi, Ellis, Ethan, Nose, Yohei, Ioannou, Giorgio, Cabal, Rafael, Del Valle, Diane M., Haines, G. Kenneth, Wang, Li, Mouw, Kent W., Samstein, Robert M., Mehrazin, Reza, Bhardwaj, Nina, Yu, Menggang, Zhao, Qianqian, Kim-Schulze, Seunghee, Sebra, Robert, Zhu, Jun, Gnjatic, Sacha, Sfakianos, John, Pal, Sumanta K.

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Secondary Germline Finding in Liquid Biopsy of a Deceased Patient; Case Report and Review of the Literature by Veyseh, Maedah, Ricker, Charite, Espenschied, Carin, Raymond, Victoria, D'Souza, Anishka, Barzi, Afsaneh

“…Liquid biopsies are increasingly used in the care of patients with advanced cancers. These tests are used to find mutations and other genomic alterations,…”
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Once Upon a Time…. Simple, Sensible Management of Venous Access for Chemotherapy Delivery in Germ Cell Tumors by Ozgun, Guliz, Haney, LaTrice, Kern, Sean, King, Jennifer, D'Souza, Anishka, Tandstad, Torgrim, Nappi, Lucia, Kollmannsberger, Christian, Nichols, Craig R

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Driver mutations associated with signatures of platinum sensitivity in germ cell tumors by Sawa, Yun Cheng, Jia, Liwei, Krause, Harris, Meagher, Margaret, Millard, Frederick, Elliott, Andrew, Lafin, John T., Jamieson, Christina, Antonarakis, Emmanuel S., D’Souza, Anishka, Giannikou, Krinio, Amatruda, James F., Daneshmand, Siamak, McKay, Rana R., Oberley, Matthew, Nabhan, Chadi, Bagrodia, Aditya

“…We sought to evaluate the genomic and transcriptomic landscapes in primary and metastatic germ cell tumors (GCTs; N  = 138) to uncover factors that drive…”
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Chemoradiation for Management of Locally Recurrent or Residual Bladder Cancer: A Case Series and Review of the Literature by Ballas, Leslie, Wei, Oren, Daneshmand, Siamak, Schuckman, Anne, Djaladat, Hooman, Aron, Monish, D’Souza, Anishka, Quinn, David, Dorff, Tanya B.

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What Comes After Immuno-Oncology Therapy for Kidney Cancer? by Zahoor, Haris, Duddalwar, Vinay, D’Souza, Anishka, Merseburger, Axel S., Quinn, David I.

“… The treatment landscape of advanced renal cell carcinoma (RCC) is rapidly evolving. Immune checkpoint inhibitors (ICI) have now become the preferred first…”
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Surviving Testicular Cancer: The Role of the Contralateral Testicle by D'souza, Anishka, Van Veldhuizen, Peter, Fung, Chunkit

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Belzutifan plus cabozantinib for patients with advanced clear cell renal cell carcinoma previously treated with immunotherapy: an open-label, single-arm, phase 2 study by Choueiri, Toni K, McDermott, David F, Merchan, Jaime, Bauer, Todd M, Figlin, Robert, Heath, Elisabeth I, Michaelson, M Dror, Arrowsmith, Edward, D'Souza, Anishka, Zhao, Song, Roy, Ananya, Perini, Rodolfo, Vickery, Donna, Tykodi, Scott S

“…Few treatment options are available for patients with advanced renal cell carcinoma who have received previous anti-PD-1-based or anti-PD-L1-based…”
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Incidence patterns of germ cell tumors in males and females from the surveillance, epidemiology, and end result nine registries (SEER9) from 1975-2016 by Barakzai, Syem Khan, Brunette, Laurie L., Ihenacho, Ugonna, Chen, Irene, D'Souza, Anishka, Cortessis, Victoria

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MP01-16 MOLECULAR DRIVERS OF ORGANOTROPISM AND CISPLATIN RESISTANCE IN GERM CELL TUMORS by Meagher, Margaret F., Sawa, Yun Cheng, Jia, Liwei, Millard, Frederick, Krause, Harris, Farrell, Alex, Elliott, Andrew, Lafin, John, Jamieson, Christina, Antonarakis, Emmanuel, D'Souza, Anishka, Giannikou, Krinio, Amatruda, James, Daneshmand, Siamak, McKay, Rana, Oberly, Matthew, Nabhan, Chadi, Bagrodia, Aditya

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Excess intermediate risk nonseminoma and regional lymph node metastases at presentation in patients with Hispanic germ cell tumor by Kolawa, Adam, Iyengar, Siddharth, Tiu-lim, Justin Wayne Wong, Arizpe, Angel, Pan, Elizabeth, Chen, Irene, Frost, Stefani, Daneshmand, Siamak, Schuckman, Anne K., Djaladat, Hooman, Quinn, David I., Tulpule, Varsha, Hu, James S., Cortessis, Victoria K., D'souza, Anishka

“…502 Background: Testicular germ cell tumors (TGCTs) is the leading solid-organ malignancy of adolescent/young adult males. Incidence is rising in all…”
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Phase Ib trial of erdafitinib (E) combined with enfortumab vedotin (EV) following platinum and PD-1/L1 inhibitors for metastatic urothelial carcinoma (mUC) with FGFR2/3 genetic alterations (GAs) by Jain, Rohit K., Heiligh, Jazlyn, Kim, Youngchul, Piekarz, Richard, Pelosof, Lorraine Cheryl, Yang, Yuanquan (Aaron), D'souza, Anishka, Wong, Risa Liang, Graham, Laura, Gupta, Sumati, Park, Anna, Synold, Timothy W., Sonpavde, Guru P.

“…625 Background: Erdafitinib (E) is a treatment option in mUCpatients with somatic FGFR2/3 GAs after progression on platinum-based chemotherapy (PBC)…”
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