Search Results - "D'auria, Maria Valeria"

Natural ligands for nuclear receptors: biology and potential therapeutic applications by D'Auria, Maria Valeria, Sepe, Valentina, Zampella, Angela

“…Nuclear receptors are key regulators of various processes including reproduction, development, and metabolism of xeno- and endobiotics. Research in the last…”
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Bioactive cembrane derivatives from the Indian Ocean soft coral, Sinularia kavarattiensis by Lillsunde, Katja-Emilia, Festa, Carmen, Adel, Harshada, De Marino, Simona, Lombardi, Valter, Tilvi, Supriya, Nawrot, Dorota A, Zampella, Angela, D'Souza, Lisette, D'Auria, Maria Valeria, Tammela, Päivi

“…Marine organisms and their metabolites represent a unique source of potential pharmaceutical substances. In this study, we examined marine-derived substances…”
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Oxygenated polyketides from Plakinastrella mamillaris as a new chemotype of PXR agonists by Festa, Carmen, D'Amore, Claudio, Renga, Barbara, Lauro, Gianluigi, De Marino, Simona, D'Auria, Maria Valeria, Bifulco, Giuseppe, Zampella, Angela, Fiorucci, Stefano

“…Further purification of the apolar extracts of the sponge Plakinastrella mamillaris, afforded a new oxygenated polyketide named gracilioether K, together with…”
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Perthamides C–F, potent human antipsoriatic cyclopeptides by Festa, Carmen, De Marino, Simona, Sepe, Valentina, D’Auria, Maria Valeria, Bifulco, Giuseppe, Andrés, Rosa, Terencio, Maria Carmen, Payá, Miguel, Debitus, Cécile, Zampella, Angela

“…Two new cyclopeptides, perthamides E and F were isolated from the polar extracts of the sponge Theonella swinhoei. The new structures, featuring an…”
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Perthamides C and D, two new potent anti-inflammatory cyclopeptides from a Solomon Lithistid sponge Theonella swinhoei by Festa, Carmen, De Marino, Simona, Sepe, Valentina, Monti, Maria Chiara, Luciano, Paolo, D'Auria, Maria Valeria, Débitus, Cecile, Bucci, Mariarosaria, Vellecco, Valentina, Zampella, Angela

“…Two new metabolites, perthamides C and D, have been isolated from the marine sponge Theonella swinhoei. Their structures were determined by interpretation of…”
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The First Total Synthesis of Solomonsterol B, a Marine Pregnane X Receptor Agonist by Sepe, Valentina, Ummarino, Raffaella, D'Auria, Maria Valeria, Renga, Barbara, Fiorucci, Stefano, Zampella, Angela

“…A concise route to the pregnane X receptor (PXR) agonist solomonsterol B, a natural product isolated from the marine sponge Theonella swinhoei, has been…”
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Solomonsterol A, a marine pregnane-X-receptor agonist, attenuates inflammation and immune dysfunction in a mouse model of arthritis by Mencarelli, Andrea, D'Amore, Claudio, Renga, Barbara, Cipriani, Sabrina, Carino, Adriana, Sepe, Valentina, Perissutti, Elisa, D'Auria, Maria Valeria, Zampella, Angela, Distrutti, Eleonora, Fiorucci, Stefano

“…In the present study we provide evidence that solomonsterol A, a selective pregnane X receptor (PXR) agonist isolated from the marine sponge Theonella…”
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Jaspamides M–P: new tryptophan modified jaspamide derivatives from the sponge Jaspis splendans by Gala, Fulvio, D'Auria, Maria Valeria, De Marino, Simona, Sepe, Valentina, Zollo, Franco, Smith, Charles D., Keller, Staci N., Zampella, Angela

“…Four new jaspamide derivatives with antimicrofilament activity were isolated from the marine sponge Jaspis splendans. Their structures were elucidated by NMR…”
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Marine and semi-synthetic hydroxysteroids as new scaffolds for pregnane X receptor modulation by Sepe, Valentina, Di Leva, Francesco Saverio, D'Amore, Claudio, Festa, Carmen, De Marino, Simona, Renga, Barbara, D'Auria, Maria Valeria, Novellino, Ettore, Limongelli, Vittorio, D'Souza, Lisette, Majik, Mahesh, Zampella, Angela, Fiorucci, Stefano

“…In recent years many sterols with unusual structures and promising biological profiles have been identified from marine sources. Here we report the isolation…”
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Preliminary structure-activity relationship on theonellasterol, a new chemotype of FXR antagonist, from the marine sponge Theonella swinhoei by Sepe, Valentina, Ummarino, Raffaella, D'Auria, Maria Valeria, Taglialatela-Scafati, Orazio, Marino, Simona De, D'Amore, Claudio, Renga, Barbara, Chini, Maria Giovanna, Bifulco, Giuseppe, Nakao, Yoichi, Fusetani, Nobuhiro, Fiorucci, Stefano, Zampella, Angela

“…Using theonellasterol as a novel FXR antagonist hit, we prepared a series of semi-synthetic derivatives in order to gain insight into the structural…”
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Enhanced Molecular Networking Shows Microbacterium sp. V1 as a Factory of Antioxidant Proline-Rich Peptides by Vitale, Giovanni Andrea, Scarpato, Silvia, Mangoni, Alfonso, D'Auria, Maria Valeria, Della Sala, Gerardo, de Pascale, Donatella

“…Two linear proline-rich peptides ( - ), bearing an N-terminal pyroglutamate, were isolated from the marine bacterium sp. V1, associated with the marine sponge…”
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Fatty Acid Synthase as Interacting Anticancer Target of the Terpenoid Myrianthic Acid Disclosed by MS-Based Proteomics Approaches by Capuano, Alessandra, D'Urso, Gilda, Gazzillo, Erica, Lauro, Gianluigi, Chini, Maria Giovanna, D'Auria, Maria Valeria, Ferraro, Maria Grazia, Iazzetti, Federica, Irace, Carlo, Bifulco, Giuseppe, Casapullo, Agostino

“…This research focuses on the target deconvolution of the natural compound myrianthic acid, a triterpenoid characterized by an ursane skeleton isolated from the…”
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Gracilioethers E–J, new oxygenated polyketides from the marine sponge Plakinastrella mamillaris by Festa, Carmen, De Marino, Simona, D'Auria, Maria Valeria, Deharo, Eric, Gonzalez, German, Deyssard, Chloe, Petek, Sylvain, Bifulco, Giuseppe, Zampella, Angela

“…Purification of the apolar extracts of the marine sponge Plakinastrella mamillaris afforded the isolation of six new oxygenated polyketides, gracilioethers…”
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Design, Synthesis, and Biological Evaluation of Potent Dual Agonists of Nuclear and Membrane Bile Acid Receptors by D’Amore, Claudio, Di Leva, Francesco Saverio, Sepe, Valentina, Renga, Barbara, Del Gaudio, Chiara, D’Auria, Maria Valeria, Zampella, Angela, Fiorucci, Stefano, Limongelli, Vittorio

“…Bile acids exert genomic and nongenomic effects by interacting with membrane G-protein-coupled receptors, including the bile acid receptor GP-BAR1, and nuclear…”
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Identification of a Sorbicillinoid-Producing Aspergillus Strain with Antimicrobial Activity Against Staphylococcus aureus: a New Polyextremophilic Marine Fungus from Barents Sea by Corral, Paulina, Esposito, Fortunato Palma, Tedesco, Pietro, Falco, Angela, Tortorella, Emiliana, Tartaglione, Luciana, Festa, Carmen, D’Auria, Maria Valeria, Gnavi, Giorgio, Varese, Giovanna Cristina, de Pascale, Donatella

“…The exploration of poorly studied areas of Earth can highly increase the possibility to discover novel bioactive compounds. In this study, the cultivable…”
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Characterization of a New Mixture of Mono-Rhamnolipids Produced by Pseudomonas gessardii Isolated from Edmonson Point (Antarctica) by Buonocore, Carmine, Tedesco, Pietro, Vitale, Giovanni Andrea, Esposito, Fortunato Palma, Giugliano, Rosa, Monti, Maria Chiara, D'Auria, Maria Valeria, de Pascale, Donatella

“…Rhamnolipids (RLs) are surface-active molecules mainly produced by Antarctica is one of the less explored places on Earth and bioprospecting for novel RL…”
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Molecular Network and Culture Media Variation Reveal a Complex Metabolic Profile in Pantoea cf. eucrina D2 Associated with an Acidified Marine Sponge by Vitale, Giovanni Andrea, Sciarretta, Martina, Cassiano, Chiara, Buonocore, Carmine, Festa, Carmen, Mazzella, Valerio, Núñez Pons, Laura, D'Auria, Maria Valeria, de Pascale, Donatella

“…The Gram-negative D2 was isolated from the marine sponge . Sponges were collected in a shallow volcanic vents system in Ischia island (South Italy), influenced…”
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Discovery that theonellasterol a marine sponge sterol is a highly selective FXR antagonist that protects against liver injury in cholestasis by Renga, Barbara, Mencarelli, Andrea, D'Amore, Claudio, Cipriani, Sabrina, D'Auria, Maria Valeria, Sepe, Valentina, Chini, Maria Giovanna, Monti, Maria Chiara, Bifulco, Giuseppe, Zampella, Angela, Fiorucci, Stefano

“…The farnesoid-x-receptor (FXR) is a bile acid sensor expressed in the liver and gastrointestinal tract. Despite FXR ligands are under investigation for…”
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Heteronemin, a marine sponge terpenoid, targets TDP-43, a key factor in several neurodegenerative disorders by Cassiano, Chiara, Esposito, Roberta, Tosco, Alessandra, Zampella, Angela, D'Auria, Maria Valeria, Riccio, Raffaele, Casapullo, Agostino, Monti, Maria Chiara

“…Trans-activation response DNA-binding protein of 43 kDa (TDP-43), a key factor in several neurodegenerative conditions, was discovered as a novel target of…”
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Phytochemical and Biological Studies of Nepeta asterotricha Rech. f. (Lamiaceae): Isolation of Nepetamoside by Goldansaz, Seyed Mostafa, Festa, Carmen, Pagano, Ester, De Marino, Simona, Finamore, Claudia, Parisi, Olga Alessandra, Borrelli, Francesca, Sonboli, Ali, D'Auria, Maria Valeria

“…The -butanolic extract, from an Iranian specimen of Rech. f. (NABE), displayed anti-inflammatory effects on lipopolysaccharide (LPS)-stimulated J774A.1…”
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