Search Results - "D'Souza, Wilissa"

5A apolipoprotein mimetic peptide promotes cholesterol efflux and reduces atherosclerosis in mice by Amar, Marcelo J A, D'Souza, Wilissa, Turner, Scott, Demosky, Stephen, Sviridov, Denis, Stonik, John, Luchoomun, Jayraz, Voogt, Jason, Hellerstein, Marc, Sviridov, Dmitri, Remaley, Alan T

“…Intravenous administration of apolipoprotein (apo) A-I complexed with phospholipid has been shown to rapidly reduce plaque size in both animal models and…”
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An apolipoprotein A-I mimetic peptide designed with a reductionist approach stimulates reverse cholesterol transport and reduces atherosclerosis in mice by Ditiatkovski, Michael, D'Souza, Wilissa, Kesani, Rajitha, Chin-Dusting, Jaye, de Haan, Judy B, Remaley, Alan, Sviridov, Dmitri

“…Apolipoprotein A-I (apoA-I) mimetic peptides are considered a promising novel therapeutic approach to prevent and/or treat atherosclerosis. An apoA-I mimetic…”
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Asymmetry in the Lipid Affinity of Bihelical Amphipathic Peptides by Sethi, Amar A., Stonik, John A., Thomas, Fairwell, Demosky, Steve J., Amar, Marcelo, Neufeld, Edward, Brewer, H. Bryan, Davidson, W. Sean, D'Souza, Wilissa, Sviridov, Dmitri, Remaley, Alan T.

“…ApoA-I contains a tandem array of amphipathic helices with varying lipid affinity, which are critical in its ability to bind and remove lipids from cells by…”
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ABCA12 Regulates ABCA1-Dependent Cholesterol Efflux from Macrophages and the Development of Atherosclerosis by Fu, Ying, Mukhamedova, Nigora, Ip, Sally, D’Souza, Wilissa, Henley, Katya J., DiTommaso, Tia, Kesani, Rajitha, Ditiatkovski, Michael, Jones, Lynelle, Lane, Rachael M., Jennings, Garry, Smyth, Ian M., Kile, Benjamin T., Sviridov, Dmitri

“…ABCA12 is involved in the transport of ceramides in skin, but it may play a wider role in lipid metabolism. We show that, in Abca12-deficient macrophages,…”
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Skeletal muscle insulin resistance associated with cholesterol-induced activation of macrophages is prevented by high density lipoprotein by Carey, Andrew L, Siebel, Andrew L, Reddy-Luthmoodoo, Medini, Natoli, Alaina K, D'Souza, Wilissa, Meikle, Peter J, Sviridov, Dmitri, Drew, Brian G, Kingwell, Bronwyn A

“…Emerging evidence suggests that high density lipoprotein (HDL) may modulate glucose metabolism through multiple mechanisms including pancreatic insulin…”
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Enhancing apolipoprotein A-I-dependent cholesterol efflux elevates cholesterol export from macrophages in vivo by Mukhamedova, Nigora, Escher, Genevieve, D'Souza, Wilissa, Tchoua, Urbain, Grant, Angela, Krozowski, Zigmund, Bukrinsky, Michael, Sviridov, Dmitri

“…Eight proteins potentially involved in cholesterol efflux [ABCA1, ABCG1, CYP27A1, phospholipid transfer protein (PLTP), scavenger receptor type BI (SR-BI),…”
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Global functional knockdown of ATP binding cassette transporter A1 stimulates development of atherosclerosis in apoE K/O mice by Mukhamedova, Nigora, D’Souza, Wilissa, Low, Hann, Kesani, Rajitha, Chimini, Giovanna, Sviridov, Dmitri

“…► Global functional knockdown of ABCA1 increases atherosclerosis. ► ABCA1 knockdown prevents reduction of plasma HDL cholesterol. ► The capacity of plasma to…”
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Impact of freezing on high-density lipoprotein functionality by Rajinda Kekulawala, J., Murphy, Andrew, D’Souza, Wilissa, Wai, Chun, Chin-Dusting, Jaye, Kingwell, Bronwyn, Sviridov, Dmitri, Mukhamedova, Nigora

“…Structural and functional properties of high-density lipoprotein (HDL) after short-term freezing in the presence or absence of 10% sucrose were compared with…”
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Structure/Function Relationships of Apolipoprotein A-I Mimetic Peptides: Implications for Antiatherogenic Activities of High-Density Lipoprotein by DʼSouza, Wilissa, Stonik, John A, Murphy, Andrew, Demosky, Steven J, Sethi, Amar A, Moore, Xiao L, Chin-Dusting, Jaye, Remaley, Alan T, Sviridov, Dmitri

“…RATIONALE:Apolipoprotein (apoA)-I mimetic peptides are a promising type of antiatherosclerosis therapy, but how the structural features of these peptides…”
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The effect of cholesteryl ester transfer protein overexpression and inhibition on reverse cholesterol transport by Tchoua, Urbain, D'Souza, Wilissa, Mukhamedova, Nigora, Blum, Denise, Niesor, Eric, Mizrahi, Jacques, Maugeais, Cyrille, Sviridov, Dmitri

“…Aims Cholesteryl ester transfer protein (CETP) has a well-established role in lipoprotein metabolism, but the effect of its overexpression or inhibition on the…”
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Asymmetry in the Lipid Affinity of Bihelical Amphipathic Peptides: A STRUCTURAL DETERMINANT FOR THE SPECIFICITY OF ABCA1-DEPENDENT CHOLESTEROL EFFLUX BY PEPTIDES by Sethi, Amar A, Stonik, John A, Thomas, Fairwell, Demosky, Steve J, Amar, Marcelo, Neufeld, Edward, Brewer, H. Bryan, Davidson, W. Sean, D'Souza, Wilissa, Sviridov, Dmitri, Remaley, Alan T

“…ApoA-I contains a tandem array of amphipathic helices with varying lipid affinity, which are critical in its ability to bind and remove lipids from cells by…”
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Structure-function relationships of apolipoprotein A-I mimetic peptides: implications for anti-atherogenic activities of high density lipoprotein by D’Souza, Wilissa, Stonik, John A., Murphy, Andrew, Demosky, Steven J., Sethi, Amar A., Moore, Xiao L., Chin-Dusting, Jaye, Remaley, Alan T., Sviridov, Dmitri

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