Search Results - "D'Souza, Shaina"

The Adjuvant Combination of dmLT and Monophosphoryl Lipid A Activates the Canonical, Nonpyroptotic NLRP3 Inflammasome in Dendritic Cells and Significantly Interacts to Expand Antigen-Specific CD4 T Cells by Bauer, David L, Bachnak, Louay, Limbert, Vanessa M, Horowitz, Rebecca M, Baudier, Robin L, D'Souza, Shaina J, Immethun, Victoria E, Kurtz, Jonathan R, Grant, Samuel B, McLachlan, James B

“…Adjuvants are often essential additions to vaccines that enhance the activation of innate immune cells, leading to more potent and protective T and B cell…”
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Thermal stress responses of Sodalis glossinidius, an indigenous bacterial symbiont of hematophagous tsetse flies by Roma, Jose Santinni, D'Souza, Shaina, Somers, Patrick J, Cabo, Leah F, Farsin, Ruhan, Aksoy, Serap, Runyen-Janecky, Laura J, Weiss, Brian L

“…Tsetse flies (Diptera: Glossinidae) house a taxonomically diverse microbiota that includes environmentally acquired bacteria, maternally transmitted symbiotic…”
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Salmonella Biofilm Formation, Chronic Infection, and Immunity Within the Intestine and Hepatobiliary Tract by Harrell, Jaikin E, Hahn, Mark M, D'Souza, Shaina J, Vasicek, Erin M, Sandala, Jenna L, Gunn, John S, McLachlan, James B

“…Within the species of , there is significant diversity represented among the numerous subspecies and serovars. Collectively, these account for microbes with…”
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IgE-activated mast cells enhance TLR4-mediated antigen-specific CD4+ T cell responses by Phong, Binh L., D’Souza, Shaina J., Baudier, Robin L., Wu, Eric, Immethun, Victoria E., Bauer, David L., McLachlan, James B.

“…Mast cells are potent mediators of allergy and asthma, yet their role in regulating adaptive immunity remains ambiguous. On the surface of mast cells, the…”
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Heme-induced genes facilitate endosymbiont (Sodalis glossinidius) colonization of the tsetse fly (Glossina morsitans) midgut by Runyen-Janecky, Laura J, Scheutzow, Jack D, Farsin, Ruhan, Cabo, Leah F, Wall, Katie E, Kuhn, Katrina M, Amador, Rashel, D'Souza, Shaina J, Vigneron, Aurelien, Weiss, Brian L

“…Tsetse flies (Glossina spp.) feed exclusively on vertebrate blood. After a blood meal, the enteric endosymbiont Sodalis glossinidius is exposed to various…”
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Establishment of isotype-switched, antigen-specific B cells in multiple mucosal tissues using non-mucosal immunization by Prior, John T., Limbert, Vanessa M., Horowitz, Rebecca M., D’Souza, Shaina J., Bachnak, Louay, Godwin, Matthew S., Bauer, David L., Harrell, Jaikin E., Morici, Lisa A., Taylor, Justin J., McLachlan, James B.

“…Although most pathogens infect the human body via mucosal surfaces, very few injectable vaccines can specifically target immune cells to these tissues where…”
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Sexual dimorphism in the antigen-specific T cell response in S. Typhimurium infections within extra-lymphoid tissues by D'Souza, Shaina J, Immethun, Vicki, Godwin, Matthew, McLachlan, James B

“…Differences in susceptibility to and severity of infectious diseases between the sexes are well established. Females often generate a beneficially stronger…”
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Ovariectomy‐Induced Arterial Stiffening is Associated with Downregulation of Tissue Resident Macrophage Markers by Kilanowski‐Doroh, Isabella, Ogola, Benard, McNally, Alexandra, D'Souza, Shaina, Rojo, Michelle, McLachlan, James, Machado, Heather, Lindsey, Sarah

“…Tissue resident macrophages play a major role in the regulation of the extracellular matrix (ECM). The ECM provides an essential scaffold and mechanical…”
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Heme-induced genes facilitate endosymbiont by Cabo, Leah F, Weiss, Brian L, Scheutzow, Jack D, Amador, Rashel, D'Souza, Shaina J, Vigneron, Aurelien, Runyen-Janecky, Laura J, Farsin, Ruhan, Wall, Katie E, Kuhn, Katrina M

“…Tsetse flies (Glossina spp.) feed exclusively on vertebrate blood. After a blood meal, the enteric endosymbiont Sodalis glossinidius is exposed to various…”
Get full text

Heme-induced genes facilitate endosymbiont midgut by Runyen-Janecky, Laura J, Scheutzow, Jack D, Farsin, Ruhan, Cabo, Leah F, Wall, Katie E, Kuhn, Katrina M, Amador, Rashel, D'Souza, Shaina J, Vigneron, Aurelien, Weiss, Brian L

“…Tsetse flies (Glossina spp.) feed exclusively on vertebrate blood. After a blood meal, the enteric endosymbiont Sodalis glossinidius is exposed to various…”
Get full text

Sexual dimorphism in the antigen-specific T cell response in S. Typhimurium infections within extra-lymphoid tissues by D’Souza, Shaina J, Godwin, Matthew, Immethun, Vicki E, Bauer, David L, McLachlan, James B

“…Differences in the immune response between the sexes, particularly in the susceptibility to and severity of infectious diseases, are well established. Females…”
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Mast cell activation enhances the TLR4-mediated antigen-specific CD4 T cell response by D’Souza, Shaina J, Phong, Binh, Immethun, Vicki E, Bauer, David L, McLachlan, James B

“…Mast cells are important immune mediators located at host environment interfaces and are most well-known as the major mediators of allergy and asthma. When…”
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The adjuvant combination of dmLT and MPL-A activates the canonical, non-pyroptotic NLRP3 inflammasome in dendritic cells and significantly interact to expand antigen-specific CD4 T cells by Bauer, David L., Bachnak, Louay, Limbert, Vanessa M., Horowitz, Rebecca M., Baudier, Robin L., D’Souza, Shaina J, Immethun, Victoria E., Kurtz, Jonathan R, Grant, Samuel B., McLachlan, James B.

“…Adjuvants are often essential additions to vaccines that enhance the activation of innate immune cells, leading to more potent and protective T and B cell…”
Get full text