Search Results - "D'Souza, David P."

Randomized Phase III Noninferiority Study Comparing Two Radiotherapy Fractionation Schedules in Patients With Low-Risk Prostate Cancer by Lee, W Robert, Dignam, James J, Amin, Mahul B, Bruner, Deborah W, Low, Daniel, Swanson, Gregory P, Shah, Amit B, D'Souza, David P, Michalski, Jeff M, Dayes, Ian S, Seaward, Samantha A, Hall, William A, Nguyen, Paul L, Pisansky, Thomas M, Faria, Sergio L, Chen, Yuhchyau, Koontz, Bridget F, Paulus, Rebecca, Sandler, Howard M

“…Conventional radiotherapy (C-RT) treatment schedules for patients with prostate cancer typically require 40 to 45 treatments that take place from > 8 to 9…”
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Exemestane Versus Anastrozole in Postmenopausal Women With Early Breast Cancer: NCIC CTG MA.27—A Randomized Controlled Phase III Trial by GOSS, Paul E, INGLE, James N, D'SOUZA, David P, CHALCHAL, Haji, SPADAFORA, Silvana, STEARNS, Vered, PEREZ, Edith A, LIEDKE, Pedro E. R, LANG, Istvan, ELLIOTT, Catherine, GELMON, Karen A, CHAPMAN, Judy-Anne W, PRITCHARD, Kathleen I, SHEPHERD, Lois E, ELLIS, Matthew J, SLEDGE, George W, BUDD, G. Thomas, RABAGLIO, Manuela, ANSARI, Rafat H, JOHNSON, David B, TOZER, Richard

“…In patients with hormone-dependent postmenopausal breast cancer, standard adjuvant therapy involves 5 years of the nonsteroidal aromatase inhibitors…”
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Image-guided radiation therapy for post-operative gynaecologic cancer: patient set up verification with and without implanted fiducial markers by Murrell, Donna H, Warner, Andrew, Benwell, Quinn, Wells, Wendy, Scott, Danielle, Velker, Vikram, Hajdok, George, D'Souza, David P

“…Intensity modulated radiotherapy (IMRT) is increasingly being used to treat gynaecological malignancies in the postoperative setting. The purpose of this study…”
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Long-Term Report of a Comprehensive Molecular and Genomic Analysis in NRG Oncology/RTOG 0424: A Phase II Study of Radiation and Temozolomide in High-Risk Grade II Glioma by Fleming, Jessica L, Pugh, Stephanie L, Fisher, Barbara J, Lesser, Glenn J, Macdonald, David R, Bell, Erica H, McElroy, Joseph P, Becker, Aline P, Timmers, Cynthia D, Aldape, Kenneth D, Rogers, C Leland, Doyle, Thomas J, Werner-Wasik, Maria, Bahary, Jean-Paul, Yu, Hsiang-Hsuan Michael, D'Souza, David P, Laack, Nadia N, Sneed, Penny K, Kwok, Young, Won, Minhee, Mehta, Minesh P, Chakravarti, Arnab

“…This study sought to determine the prognostic significance of the WHO-defined glioma molecular subgroups along with additional alterations, including promoter…”
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In regards to Da Silva Franca et al.: “Localized prostate cancer with intermediate- or high-risk features treated with combined external beam radiotherapy and iodine-125 seed brachytherapy” (Brachytherapy 2010; 9(4): 307-312) by Patil, Nikhilesh G., MD, D'Souza, David P., MD

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Is Ultrahypofractionated Whole Pelvis Radiation Therapy (WPRT) as Well Tolerated as Conventionally Fractionated WPRT in Patients With Prostate Cancer? Early Results From the HOPE Trial by Mendez, Lucas C., Crook, Juanita, Martell, Kevin, Schaly, Bryan, Hoover, Douglas A., Dhar, Aneesh, Velker, Vikram, Ahmad, Belal, Lock, Michael, Halperin, Ross, Warner, Andrew, Bauman, Glenn S., D'Souza, David P.

“…The aim of this work was to evaluate the acute toxicity and quality-of-life (QOL) impact of ultrahypofractionated whole pelvis radiation therapy (WPRT)…”
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Intensity-Modulated Radiation Therapy Reduces Patient-Reported Chronic Toxicity Compared With Conventional Pelvic Radiation Therapy: Updated Results of a Phase III Trial by Yeung, Anamaria R, Deshmukh, Snehal, Klopp, Ann H, Gil, Karen M, Wenzel, Lari, Westin, Shannon N, Konski, Andre A, Gaffney, David K, Small, Jr, William, Thompson, J Spencer, Doncals, Desiree E, Cantuaria, Guilherme H C, D'Souza, David P, Chang, Amy, Kundapur, Vijayananda, Mohan, Dasarahally S, Haas, Michael L, Kim, Yong Bae, Ferguson, Catherine L, Pugh, Stephanie L, Kachnic, Lisa A, Bruner, Deborah W

“…JCO The purpose of this update was to determine differences in patient-reported chronic toxicity and disease outcomes with intensity-modulated radiation…”
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3D image-guided interstitial brachytherapy for primary vaginal cancer: A multi-institutional experience by Goodman, Christopher D., Mendez, Lucas C., Velker, Vikram, Weiss, Yonatan, Leung, Eric, Louie, Alexander V., Warner, Andrew, Hajdok, George, D'Souza, David P.

“…High dose rate (HDR) interstitial brachytherapy (ISBT) boost is integral for definitive radiation treatment of primary vaginal cancer. Technological advances…”
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Lymphedema in women with breast cancer: characteristics of patients screened for a randomized trial by Dayes, Ian S., Levine, Mark N., Julian, J. A., Pritchard, Kathleen I., D’Souza, David P., Kligman, Lyn, Reise, Donnalue, Wiernikowski, Jennifer A., Bonilla, L., Whelan, T. J.

“…Introduction Accrual rates for a randomized trial of decongestive therapy in breast cancer patients with lymphedema were lower than anticipated. In two…”
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Is prostate brachytherapy a dying art? Trends and variation in the definitive management of prostate cancer in Ontario, Canada by Corkum, Mark T., Morton, Gerard, Louie, Alexander V., Bauman, Glenn S., Mendez, Lucas C., Chin, Joseph, D'Souza, David P., Dinniwell, Robert E., Velker, Vikram M., Saskin, Refik, Warner, Andrew, Rodrigues, George B.

“…•Between 2007-2017, prostate brachytherapy (BT) use increased in Ontario, Canada.•A greater increase in BT boost compared to BT monotherapy was observed.•If…”
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Neighborhood Deprivation and Rurality Associated With Patient-Reported Outcomes and Survival in Men With Prostate Cancer in NRG Oncology RTOG 0415 by Bai, Jinbing, Pugh, Stephanie L., Eldridge, Ronald, Yeager, Katherine A., Zhang, Qi, Lee, W. Robert, Shah, Amit B., Dayes, Ian S., D'Souza, David P., Michalski, Jeff M., Efstathiou, Jason A., Longo, John M., Pisansky, Thomas M., Maier, Jordan M., Faria, Sergio L., Desai, Anand B., Seaward, Samantha A., Sandler, Howard M., Cooley, Mary E., Bruner, Deborah W.

“…Rurality and neighborhood deprivation can contribute to poor patient-reported outcomes, which have not been systematically evaluated in patients with specific…”
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Adjunctive Statistical Standardization of Adjuvant Estrogen Receptor and Progesterone Receptor in Canadian Cancer Trials Group MA.27 Postmenopausal Breast Cancer Trial of Exemestane Versus Anastrozole by Chapman, Judith-Anne W, Bayani, Jane, SenGupta, Sandip, Bartlett, John M S, Piper, Tammy, Quintayo, Mary Anne, Virk, Shakeel, Goss, Paul E, Ingle, James N, Ellis, Matthew J, Sledge, George W, Budd, G Thomas, Rabaglio, Manuela, Ansari, Rafat H, Tozer, Richard, D'Souza, David P, Chalchal, Haji, Spadafora, Silvana, Stearns, Vered, Perez, Edith A, Gelmon, Karen A, Whelan, Timothy J, Elliott, Catherine, Shepherd, Lois E, Chen, Bingshu E, Taylor, Karen J

“…ASCO/College of American Pathologists guidelines recommend reporting estrogen receptor (ER) and progesterone receptor (PgR) as positive with (1%-100%)…”
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Unique properties of a subset of human pluripotent stem cells with high capacity for self-renewal by Lau, Kevin X., Mason, Elizabeth A., Kie, Joshua, De Souza, David P., Kloehn, Joachim, Tull, Dedreia, McConville, Malcolm J., Keniry, Andrew, Beck, Tamara, Blewitt, Marnie E., Ritchie, Matthew E., Naik, Shalin H., Zalcenstein, Daniela, Korn, Othmar, Su, Shian, Romero, Irene Gallego, Spruce, Catrina, Baker, Christopher L., McGarr, Tracy C., Wells, Christine A., Pera, Martin F.

“…Archetypal human pluripotent stem cells (hPSC) are widely considered to be equivalent in developmental status to mouse epiblast stem cells, which correspond to…”
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Image-guided cervix high-dose-rate brachytherapy treatment planning: Does custom computed tomography planning for each insertion provide better conformal avoidance of organs at risk? by Davidson, Melanie T.M, Yuen, Jasper, D'Souza, David P, Batchelar, Deidre L

“…Abstract Purpose Intracavitary high-dose-rate (HDR) brachytherapy (BT) for cervical cancer involves multiple applicator insertions. Our study addresses whether…”
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Circadian and wake-dependent changes in human plasma polar metabolites during prolonged wakefulness: A preliminary analysis by Grant, Leilah K., Ftouni, Suzanne, Nijagal, Brunda, De Souza, David P., Tull, Dedreia, McConville, Malcolm J., Rajaratnam, Shantha M. W., Lockley, Steven W., Anderson, Clare

“…Establishing circadian and wake-dependent changes in the human metabolome are critical for understanding and treating human diseases due to circadian…”
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Quality-adjusted survival in women with gynecologic malignancies receiving IMRT after surgery: A Ppatient Rreported Ooutcome study of NRG oncology's RTOG 1203 by Konski, Andre, Deshmukh, Snehal, Klopp, Ann H., Yeung, Anamaria R., Westin, Shannon N., Thompson, J. Spencer, Doncals, Desiree E., Cantuaria, Guilherme H.C., D'Souza, David P., Chang, Amy, Kundapur, Vijayananda, Mohan, Dasarahally S., Haas, Michael L., Kim, Yong Bae, Ferguson, Catherine L., Pugh, Stephanie L., Kachnic, Lisa A., Bruner, Deborah W.

“…NRG/RTOG 1203 compared 3-D conformal radiotherapy (3D CRT) to intensity-modulated radiotherapy (IMRT) in patients with endometrial or cervical cancer requiring…”
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Feeding an unsalable carrot total-mixed ration altered bacterial amino acid degradation in the rumen of lambs by Forwood, Daniel L., Innes, David J., Parra, Mariano C., Stark, Terra, de Souza, David P., Chaves, Alex V., Meale, Sarah J.

“…The objective of this study was to determine the influence of a total-mixed ration including unsalable carrots at 45% DM on the rumen microbiome; and the…”
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The role of adjuvant therapy in stage IA serous and clear cell uterine cancer: A multi-institutional pooled analysis by Qu, X. Melody, Velker, Vikram M., Leung, Eric, Kwon, Janice S., Elshaikh, Mohamed A., Kong, Iwa, Logie, Natalie A., Mendez, Lucas C., van der Putten, Louis J., Donovan, Elysia K., Munkarah, Adnan R., Wiebe, Ericka M., Parra-Herran, Carlos, Warner, Andrew, Louie, Alexander V., D'Souza, David P.

“…As the optimal adjuvant management of stage IA serous or clear cell endometrial cancer is controversial, a multi-institutional review was conducted with the…”
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Is hypofractionated whole pelvis radiotherapy (WPRT) as well tolerated as conventionally fractionated WPRT in prostate cancer patients? The HOPE trial by Mendez, Lucas C, Arifin, Andrew J, Bauman, Glenn S, Velker, Vikram M, Ahmad, Belal, Lock, Michael, Venkatesan, Varagur M, Sexton, Tracy L, Rodrigues, George B, Chen, Jeff, Schaly, Bryan, Warner, Andrew, D'Souza, David P

“…Patients with high-risk prostate cancer are at increased risk of lymph node metastasis and are thought to benefit from whole pelvis radiotherapy (WPRT). There…”
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Quality-of-Life Outcomes and Toxic Effects Among Patients With Cancers of the Uterus Treated With Stereotactic Pelvic Adjuvant Radiation Therapy: The SPARTACUS Phase 1/2 Nonrandomized Controlled Trial by Leung, Eric, Gladwish, Adam P, Davidson, Melanie, Taggar, Amandeep, Velker, Vikram, Barnes, Elizabeth, Mendez, Lucas, Donovan, Elysia, Gien, Lilian T, Covens, Allan, Vicus, Danielle, Kupets, Rachel, MacKay, Helen, Han, Kathy, Cheung, Patrick, Zhang, Liying, Loblaw, Andrew, D'Souza, David P

“…Adjuvant radiation plays an important role in reducing locoregional recurrence in patients with uterine cancer. Although hypofractionated radiotherapy may…”
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