Search Results - "D'Onofrio, Loretta"

Impact of BMI on HER2+ metastatic breast cancer patients treated with pertuzumab and/or trastuzumab emtansine. Real‐world evidence by Krasniqi, Eriseld, Pizzuti, Laura, Barchiesi, Giacomo, Sergi, Domenico, Carpano, Silvia, Botti, Claudio, Kayal, Ramy, Sanguineti, Giuseppe, Marchetti, Paolo, Botticelli, Andrea, Marinelli, Daniele, Gamucci, Teresa, Natoli, Clara, Grassadonia, Antonino, Tinari, Nicola, Tomao, Silverio, Tonini, Giuseppe, Santini, Daniele, Michelotti, Aandrea, Mentuccia, Lucia, Vaccaro, Aangela, Magnolfi, Emanuela, Gelibter, Alain, Magri, Valentina, Cortesi, Enrico, D’Onofrio, Loretta, Cassano, Alessandra, Cazzaniga, Marina, Moscetti, Luca, Fabbri, Agnese, Scinto, Angelo Fedele, Corsi, Domenico, Carbognin, Luisa, Bria, Emilio, La Verde, Nicla, Garufi, Carlo, Di Stefano, Pia, Mirabelli, Rossana, Veltri, Enzo, Paris, Ida, Giotta, Francesco, Lorusso, Vito, Landucci, Elisa, Ficorella, Corrado, Roselli, Mario, Adamo, Vincenzo, Ricciardi, Giuseppina, Russo, Antonio, Valerio, Maria Rosaria, Berardi, Rossana, Pistelli, Mirco, Cannita, Katia, Zamagni, Claudio, Garrone, Ornella, Baldini, Editta, Livi, Lorenzo, Meattini, Icro, Del Medico, Pietro, Generali, Daniele, De Maria, Ruggero, Risi, Emanuela, Ciliberto, Gennaro, Villa, Alice, Sperduti, Isabella, Mazzotta, Marco, Barba, Maddalena, Giordano, Antonio, Vici, Patrizia

“…Body mass index (BMI) is a main indicator of obesity and its association with breast cancer is well established. However, little is known in the metastatic…”
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New molecular insights in tobacco-induced lung cancer by Tonini, Giuseppe, D'Onofrio, Loretta, Dell'Aquila, Emanuela, Pezzuto, Aldo

“…We know that cigarette smoking is a leading preventable cause of carcinogenesis in lung cancer. Cigarette smoke is a mixture of more than 5000 chemical…”
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Classic Kaposi Sarcoma: to treat or not to treat? by Vincenzi, Bruno, D'Onofrio, Loretta, Frezza, Anna Maria, Grasso, Rosario Francesco, Fausti, Valentina, Santini, Daniele, Dei Tos, Angelo Paolo, Tonini, Giuseppe

“…Classic Kaposi Sarcoma (KS) is vascular sarcoma, known to be more common in Mediterranean elderly men and characterized by an indolent clinical behavior. To…”
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Pazopanib and pancreatic toxicity: a case report by Russano, Marco, Vincenzi, Bruno, Venditti, Olga, D'Onofrio, Loretta, Ratta, Raffaele, Guida, Francesco M, Tonini, Giuseppe, Santini, Daniele

“…Pazopanib is an oral multitargeted tyrosine-kinase inhibitor, used as a single agent to treat advanced renal cell carcinoma. Treatment with other…”
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Prognostic Relevance of Objective Response According to EASL Criteria and mRECIST Criteria in Hepatocellular Carcinoma Patients Treated with Loco-Regional Therapies: A Literature-Based Meta-Analysis by Vincenzi, Bruno, Di Maio, Massimo, Silletta, Marianna, D'Onofrio, Loretta, Spoto, Chiara, Piccirillo, Maria Carmela, Daniele, Gennaro, Comito, Francesca, Maci, Eliana, Bronte, Giuseppe, Russo, Antonio, Santini, Daniele, Perrone, Francesco, Tonini, Giuseppe

“…The European Association for the Study of the Liver (EASL) criteria and the modified Response Evaluation Criteria in Solid Tumors (mRECIST) are currently…”
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Triple positive breast cancer: A distinct subtype? by Vici, Patrizia, Pizzuti, Laura, Natoli, Clara, Gamucci, Teresa, Di Lauro, Luigi, Barba, Maddalena, Sergi, Domenico, Botti, Claudio, Michelotti, Andrea, Moscetti, Luca, Mariani, Luciano, Izzo, Fiorentino, D’Onofrio, Loretta, Sperduti, Isabella, Conti, Francesca, Rossi, Valentina, Cassano, Alessandra, Maugeri-Saccà, Marcello, Mottolese, Marcella, Marchetti, Paolo

“…Highlights • HER-2, ER and PgR have a key role in treatment decision making in breast cancer. • Triple positive (TP) tumours exhibit a unique clinical and…”
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Denosumab for cancer-related bone loss by Dell'Aquila, Emanuela, Armento, Grazia, Iuliani, Michele, Simonetti, Sonia, D'Onofrio, Loretta, Zeppola, Tea, Madaudo, Cristina, Russano, Marco, Citarella, Fabrizio, Ribelli, Giulia, Pantano, Francesco, Vincenzi, Bruno, Tonini, Giuseppe, Santini, Daniele

“…Prolonged use of anti-cancer treatments in breast and prostate tumors alters physiological bone turnover leading to adverse skeletal related events, such as…”
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Fasting glucose and body mass index as predictors of activity in breast cancer patients treated with everolimus-exemestane: The EverExt study by Pizzuti, Laura, Marchetti, Paolo, Natoli, Clara, Gamucci, Teresa, Santini, Daniele, Scinto, Angelo Fedele, Iezzi, Laura, Mentuccia, Lucia, D’Onofrio, Loretta, Botticelli, Andrea, Moscetti, Luca, Sperati, Francesca, Botti, Claudio, Ferranti, Francesca, Buglioni, Simonetta, Sanguineti, Giuseppe, Di Filippo, Simona, di Lauro, Luigi, Sergi, Domenico, Catenaro, Teresa, Tomao, Silverio, Giordano, Antonio, Maugeri-Saccà, Marcello, Barba, Maddalena, Vici, Patrizia

“…Evidence on everolimus in breast cancer has placed hyperglycemia among the most common high grade adverse events. Anthropometrics and biomarkers of glucose…”
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A multicenter REtrospective observational study of first-line treatment with PERtuzumab, trastuzumab and taxanes for advanced HER2 positive breast cancer patients. RePer Study by Gamucci, Teresa, Pizzuti, Laura, Natoli, Clara, Mentuccia, Lucia, Sperduti, Isabella, Barba, Maddalena, Sergi, Domenico, Iezzi, Laura, Maugeri-Saccà, Marcello, Vaccaro, Angela, Magnolfi, Emanuela, Gelibter, Alain, Barchiesi, Giacomo, Magri, Valentina, D'Onofrio, Loretta, Cassano, Alessandra, Rossi, Ernesto, Botticelli, Andrea, Moscetti, Luca, Omarini, Claudia, Fabbri, Maria Agnese, Scinto, Angelo Fedele, Corsi, Domenico, Carbognin, Luisa, Mazzotta, Marco, Bria, Emilio, Foglietta, Jennifer, Samaritani, Riccardo, Garufi, Carlo, Mariani, Luciano, Barni, Sandro, Mirabelli, Rosanna, Sarmiento, Roberta, Graziano, Vincenzo, Santini, Daniele, Marchetti, Paolo, Tonini, Giuseppe, Di Lauro, Luigi, Sanguineti, Giuseppe, Paoletti, Giancarlo, Tomao, Silverio, De Maria, Ruggero, Veltri, Enzo, Paris, Ida, Giotta, Francesco, Latorre, Agnese, Giordano, Antonio, Ciliberto, Gennaro, Vici, Patrizia

“…We carried out a retrospective observational study of 264 HER2-positive advanced breast cancer (ABC) patients to explore the efficacy of first-line treatment…”
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Bisphosphonates as anticancer agents in early breast cancer: preclinical and clinical evidence by Santini, Daniele, Stumbo, Luciano, Spoto, Chiara, D'Onofrio, Loretta, Pantano, Francesco, Iuliani, Michele, Fioramonti, Marco, Zoccoli, Alice, Ribelli, Giulia, Virzì, Vladimir, Vincenzi, Bruno, Tonini, Giuseppe

“…Bisphosphonates (BPs) are approved as standard therapy in breast cancer for the treatment of bone metastases, since they were demonstrated to reduce the…”
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Long-term treatment with eribulin in heavily pretreated women with metastatic breast cancer: a case series by Morritti, Maria, Iodice, Giuseppe, Melaccio, Assunta, D'Onofrio, Loretta, Bergnolo, Paola, Boglione, Antonella, Comandone, Alessandro, Molinaro, Peppina, Garigliano, Danula

“…During the last decades, much effort has been made to develop and test treatments for advanced/metastatic breast cancer (MBC) able to prolong survival and…”
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A retrospective multicentric observational study of trastuzumab emtansine in HER2 positive metastatic breast cancer: a real-world experience by Vici, Patrizia, Pizzuti, Laura, Michelotti, Andrea, Sperduti, Isabella, Natoli, Clara, Mentuccia, Lucia, Di Lauro, Luigi, Sergi, Domenico, Marchetti, Paolo, Santini, Daniele, Magnolfi, Emanuela, Iezzi, Laura, Moscetti, Luca, Fabbri, Agnese, Cassano, Alessandra, Grassadonia, Antonino, Omarini, Claudia, Piacentini, Federico, Botticelli, Andrea, Bertolini, Ilaria, Scinto, Angelo Fedele, Zampa, Germano, Mauri, Maria, D'Onofrio, Loretta, Sini, Valentina, Barba, Maddalena, Maugeri-Saccà, Marcello, Rossi, Ernesto, Landucci, Elisabetta, Tomao, Silverio, Alberti, Antonio Maria, Giotta, Francesco, Ficorella, Corrado, Adamo, Vincenzo, Russo, Antonio, Lorusso, Vito, Cannita, Katia, Barni, Sandro, Laudadio, Lucio, Greco, Filippo, Garrone, Ornella, Della Giulia, Marina, Marolla, Paolo, Sanguineti, Giuseppe, Di Cocco, Barbara, Ciliberto, Gennaro, De Maria, Ruggero, Gamucci, Teresa

“…We addressed trastuzumab emtansine (T-DM1) efficacy in HER2+ metastatic breast cancer patients treated in real-world practice, and its activity in…”
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"Triple positive" early breast cancer: an observational multicenter retrospective analysis of outcome by Vici, Patrizia, Pizzuti, Laura, Sperduti, Isabella, Frassoldati, Antonio, Natoli, Clara, Gamucci, Teresa, Tomao, Silverio, Michelotti, Andrea, Moscetti, Luca, Gori, Stefania, Baldini, Editta, Giotta, Francesco, Cassano, Alessandra, Santini, Daniele, Giannarelli, Diana, Di Lauro, Luigi, Corsi, Domenico Cristiano, Marchetti, Paolo, Sini, Valentina, Sergi, Domenico, Barba, Maddalena, Maugeri-Saccà, Marcello, Russillo, Michelangelo, Mentuccia, Lucia, D'Onofrio, Loretta, Iezzi, Laura, Scinto, Angelo Fedele, Da Ros, Lucia, Bertolini, Ilaria, Basile, Maria Luisa, Rossi, Valentina, De Maria, Ruggero, Montemurro, Filippo

“…We recently found that trastuzumab benefit may be lower in a small subset of early breast cancer (BC) patients (pts) with tumors expressing high levels of both…”
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Neoadjuvant treatment of biliary tract cancer: state-of-the-art and new perspectives by Imperatori, Marco, D'Onofrio, Loretta, Marrucci, Eleonora, Pantano, Francesco, Zoccoli, Alice, Tonini, Giuseppe

“…Gall bladder cancer (GBC), and intrahepatic and extrahepatic (perihilar or distal bile duct's) cholangiocarcinomas (CCA) are usually diagnosed in locally…”
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Abstract P5-14-01: Eribulin tolerability and correlation between neuropathy and a set of polymorphisms in metastatic breast cancer patients. Results from the PAINTER (Polymorphism And Incidence of Toxicity in ERibulin treatment) study by La Verde, Nicla, Damia, Giovanna, Garrone, Ornella, D'Onofrio, Loretta, Fabi, Alessandra, Ciccarese, Mariangela, Generali, Daniele, Nunzi, Martina, Poletto, Elena, Pedrazzoli, Paolo, Cretella, Elisabetta, Scandurra, Giuseppa, Meattini, Icro, Bertolini, Alessandro S, Cavanna, Luigi, Romagnoli, Emanuela, Legramandi, Lorenzo, Guffanti, Federica, Rulli, Eliana, Moretti, Anna, Bocci, Barbara, Farina, Gabriella

“…BACKGROUND: Metastatic breast cancer (MBC) is an incurable disease and its treatment focuses mainly on prolonging patients (pts) survival and improving their…”
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Clinical features of male breast cancer and multimodal treatment: a comment to retrospective survey analysis at Italian centers by D'Onofrio, Loretta, Tonini, Giuseppe, Santini, Daniele

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Correlation between NDRG1 gene polymorphism and neuropathy (N) in metastatic breast cancer (MBC) patients (pts) enrolled in the PAINTER study (Polymorphism And INcidence of Toxicity in ERibulin treatment) by La Verde, Nicla Maria, Damia, Giovanna, Garrone, Ornella, D'Onofrio, Loretta, Fabi, Alessandra, Ciccarese, Mariangela, Generali, Daniele Giulio, Nunzi, Martina, Poletto, Elena, Pedrazzoli, Paolo, Cretella, Elisabetta, Scandurra, Giuseppa, Meattini, Icro, Bertolini, Alessandro Stefano, Cavanna, Luigi, Romagnoli, Emanuela, Legramandi, Lorenzo, Guffanti, Federica, Bocci, Barbara, Farina, Gabriella

“…Abstract only 3116 Background: MBC is an incurable disease and therefore treatment focuses mainly on prolonging pts survival and improving quality of life…”
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Distinct HR expression patterns significantly affect the clinical behavior of metastatic HER2+ breast cancer and degree of benefit from novel anti‐HER2 agents in the real world setting by Pizzuti, Laura, Krasniqi, Eriseld, Barchiesi, Giacomo, Della Giulia, Marina, Izzo, Fiorentino, Sanguineti, Giuseppe, Marchetti, Paolo, Mazzotta, Marco, Giusti, Raffaele, Botticelli, Andrea, Gamucci, Teresa, Natoli, Clara, Grassadonia, Antonino, Tinari, Nicola, Iezzi, Laura, Tomao, Silverio, Tomao, Federica, Tonini, Giuseppe, Santini, Daniele, Astone, Antonio, Michelotti, Andrea, De Angelis, Claudia, Mentuccia, Lucia, Vaccaro, Angela, Magnolfi, Emanuela, Gelibter, Alain, Magri, Valentina, Cortesi, Enrico, D'Onofrio, Loretta, Cassano, Alessandra, Rossi, Ernesto, Cazzaniga, Marina, Moscetti, Luca, Omarini, Claudia, Piacentini, Federico, Fabbri, Maria A., Scinto, Angelo F., Corsi, Domenico, Carbognin, Luisa, Bria, Emilio, La Verde, Nicla, Samaritani, Riccardo, Garufi, Carlo, Barni, Sandro, Mirabelli, Rosanna, Sarmiento, Roberta, Veltri, Enzo M., D'Auria, Giuliana, Paris, Ida, Giotta, Francesco, Lorusso, Vito, Cardillo, Franca, Landucci, Elisabetta, Mauri, Maria, Ficorella, Corrado, Roselli, Mario, Adamo, Vincenzo, Ricciardi, Giuseppina R.R., Russo, Antonio, Berardi, Rossana, Pistelli, Mirco, Fiorio, Elena, Cannita, Katia, Sini, Valentina, D'Ostilio, Nicola, Foglietta, Jennifer, Greco, Filippo, Zamagni, Claudio, Garrone, Ornella, Di Cocco, Barbara, Baldini, Editta, Livi, Lorenzo, Desideri, Isacco, Meattini, Icro, Sarobba, Giuseppina, Del Medico, Pietro, De Tursi, Michele, Generali, Daniele, De Maria, Ruggero, Risi, Emanuela, Ciliberto, Gennaro, Sperduti, Isabella, Villa, Alice, Barba, Maddalena, Di Leo, Angelo, Vici, Patrizia

“…We analyzed data from 738 HER2‐positive metastatic breast cancer (mbc) patients treated with pertuzumab‐based regimens and/or T‐DM1 at 45 Italian centers…”
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Efficacy of pertuzumab in combination with trastuzumab and a taxane in first-line treatment for metastatic breast cancer (MBC): A multicenter, retrospective, observational study by Gamucci, Teresa, Mentuccia, Lucia, Sperduti, Isabella, Gelibter, Alain, D'Onofrio, Loretta, Cassano, Alessandra, Iezzi, Laura, Botticelli, Andrea, Pizzuti, Laura, Moscetti, Luca, Barchiesi, Giacomo, Scinto, Fedele, Carbognin, Luisa, Cursano, Maria Concetta, Foglietta, Jennifer, Rossi, Ernesto, Barni, Sandro, Graziano, Vincenzo, Magnolfi, Emanuela, Vici, Patrizia

“…Abstract only e12504 Background: Pertuzumab (P) , Trastuzumab (T) and Docetaxel (D) is standard first-line treatment in patients (pts) with HER2 + metastatic…”
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Moving from the CLEOPATRA study to real life: Results from the G.O.N.O. SUPER trial by Garrone, Ornella, Giarratano, Tommaso, Saggia, Chiara, Bertolini, Ilaria, Beano, Alessandra, Blondeaux, Eva, Riva, Francesca, D'Onofrio, Loretta, Merlini, Laura, Coltelli, Luigi, La Verde, Nicla Maria, Vandone, Anna Maria, Milani, Andrea, Collovà, Elena, Ardito, Raffaele, Airoldi, Mario, De Conciliis, Enrico, Blasi, Livio, Di Maio, Massimo, Merlano, Marco Carlo

“…Abstract only…”
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